2,803 research outputs found
Data handling methods and target detection results for multibeam and sidescan data collected as part of the search for SwissAir Flight 111
The crash of SwissAir Flight 111, off Nova Scotia in September 1998, triggered one of the largest seabed search surveys in Canadian history. The primary search tools used were sidescan sonars (both conventional and focussed types) and multibeam sonars. The processed search data needed to be distributed on a daily basis to other elements of the fleet for precise location of divers and other optical seabed search instruments (including laser linescan and ROV video). As a result of the glacial history of the region, many natural targets, similar in gross nature to aircraft debris were present. These included widespread linear bedrock outcrop patterns together with near ubiquitous glacial erratic boulders. Because of the severely broken-up nature of the remaining aircraft debris, sidescan imaging alone was often insufficient to unambiguously identify targets. The complementary attributes of higher resolution, but poorly located, sidescan imagery together with slightly lower resolution, but excellently navigated multibeam sonar proved to be one of critical factors in the success of the search. It proved necessary to rely heavily on the regional context of the seabed (provided by the multibeam sonar bathymetry and backscatter imagery) to separate natural geomorphic targets from anomalous anthropogenic debris. In order to confidently prove or disprove a potential target, the interpreter required simultaneous access to the full resolution sidescan data in the geographic context of the multibeam framework. Specific software tools had to be adapted or developed shipboard to provide this capability. Whilst developed specifically for this application, these survey tools can provide improved processing speed and confidence as part of more general mine hunting, hydrographic, engineering or scientific surveys
The Local Effects of Cosmological Variations in Physical 'Constants' and Scalar Fields I. Spherically Symmetric Spacetimes
We apply the method of matched asymptotic expansions to analyse whether
cosmological variations in physical `constants' and scalar fields are
detectable, locally, on the surface of local gravitationally bound systems such
as planets and stars, or inside virialised systems like galaxies and clusters.
We assume spherical symmetry and derive a sufficient condition for the local
time variation of the scalar fields that drive varying constants to track the
cosmological one. We calculate a number of specific examples in detail by
matching the Schwarzschild spacetime to spherically symmetric inhomogeneous
Tolman-Bondi metrics in an intermediate region by rigorously construction
matched asymptotic expansions on cosmological and local astronomical scales
which overlap in an intermediate domain. We conclude that, independent of the
details of the scalar-field theory describing the varying `constant', the
condition for cosmological variations to be measured locally is almost always
satisfied in physically realistic situations. The proof of this statement
provides a rigorous justification for using terrestrial experiments and solar
system observations to constrain or detect any cosmological time variations in
the traditional `constants' of Nature.Comment: 30 pages, 3 figures; corrected typo
An analysis of likes and dislikes for history and geography of 3360 sixth grade children
Thesis (Ed.M.)--Boston Universit
Identification of a novel retroviral gene unique to human immunodeficiency virus type 2 and simian immunodeficiency virus SIVMAC
Human and simian immunodeficiency-associated retroviruses are extraordinarily complex, containing at least five genes, tat, art, sor, R, and 3' orf, in addition to the structural genes gag, pol, and env. Recently, nucleotide sequence analysis of human immunodeficiency virus type 2 (HIV-2) and simian immunodeficiency virus SIVMAC revealed the existence of still another open reading frame, termed X, which is highly conserved between these two viruses but absent from HIV-1. In this report, we demonstrate for the first time that the X open reading frame represents a functional retroviral gene in both HIV-2 and SIVMAC and that it encodes a virion-associated protein of 14 and 12 kilodaltons, respectively. We also describe the production of recombinant TrpE/X fusion proteins in Escherichia coli and show that sera from some HIV-2-infected individuals specifically recognize these proteins
Observation of bosonic coalescence of photon pairs
Quantum theory predicts that two indistinguishable photons incident on a
beam-splitter interferometer stick together as they exit the device (the pair
emerges randomly from one port or the other). We use a special
photon-number-resolving energy detector for a direct loophole-free observation
of this quantum-interference phenomenon. Simultaneous measurements from two
such detectors, one at each beam-splitter output port, confirm the absence of
cross-coincidences.Comment: 4 pages, 2 figures, submitted to Phys. Rev. Let
International Space Station Common Cabin Air Assembly Condensing Heat Exchanger Hydrophilic Coating Operation, Recovery, and Lessons Learned
The ability to control the temperature and humidity of an environment or habitat is critical for human survival. These factors are important to maintaining human health and comfort, as well as maintaining mechanical and electrical equipment in good working order to support the human and to accomplish mission objectives. The temperature and humidity of the International Space Station (ISS) United States On-orbit Segment (USOS) cabin air is controlled by the Common Cabin Air Assembly (CCAA). The CCAA consists of a fan, a condensing heat exchanger (CHX), an air/water separator, temperature and liquid sensors, and electrical controlling hardware and software. The CHX is the primary component responsible for control of temperature and humidity. The CCAA CHX contains a chemical coating that was developed to be hydrophilic and thus attract water from the humid influent air. This attraction forms the basis for water removal and therefore cabin humidity control. However, there have been several instances of CHX coatings becoming hydrophobic and repelling water. When this behavior is observed in an operational CHX in the ISS segments, the unit s ability to remove moisture from the air is compromised and the result is liquid water carryover into downstream ducting and systems. This water carryover can have detrimental effects on the ISS cabin atmosphere quality and on the health of downstream hardware. If the water carryover is severe and widespread, this behavior can result in an inability to maintain humidity levels in the USOS. This paper will describe the operation of the five CCAAs within the USOS, the potential causes of the hydrophobic condition, and the impacts of the resulting water carryover to downstream systems. It will describe the history of this behavior and the actual observed impacts to the ISS USOS. Information on mitigation steps to protect the health of future CHX hydrophilic coatings as well as remediation and recovery of the full heat exchanger will be discussed
Astro-WISE: Chaining to the Universe
The recent explosion of recorded digital data and its processed derivatives
threatens to overwhelm researchers when analysing their experimental data or
when looking up data items in archives and file systems. While current hardware
developments allow to acquire, process and store 100s of terabytes of data at
the cost of a modern sports car, the software systems to handle these data are
lagging behind. This general problem is recognized and addressed by various
scientific communities, e.g., DATAGRID/EGEE federates compute and storage power
over the high-energy physical community, while the astronomical community is
building an Internet geared Virtual Observatory, connecting archival data.
These large projects either focus on a specific distribution aspect or aim to
connect many sub-communities and have a relatively long trajectory for setting
standards and a common layer. Here, we report "first light" of a very different
solution to the problem initiated by a smaller astronomical IT community. It
provides the abstract "scientific information layer" which integrates
distributed scientific analysis with distributed processing and federated
archiving and publishing. By designing new abstractions and mixing in old ones,
a Science Information System with fully scalable cornerstones has been
achieved, transforming data systems into knowledge systems. This break-through
is facilitated by the full end-to-end linking of all dependent data items,
which allows full backward chaining from the observer/researcher to the
experiment. Key is the notion that information is intrinsic in nature and thus
is the data acquired by a scientific experiment. The new abstraction is that
software systems guide the user to that intrinsic information by forcing full
backward and forward chaining in the data modelling.Comment: To be published in ADASS XVI ASP Conference Series, 2006, R. Shaw, F.
Hill and D. Bell, ed
Continental-scale assessment of genetic diversity and population structure in quaking aspen (Populus tremuloides)
Aim: Quaking aspen (Populus tremuloides) has the largest natural distribution of any tree native to North America. The primary objectives of this study were to characterize range-wide genetic diversity and genetic structuring in quaking aspen, and to assess the influence of glacial history and rear-edge dynamics.
Location: North America.
Methods: Using a sample set representing the full longitudinal and latitudinal extent of the speciesâ distribution, we examined geographical patterns of genetic diversity and structuring using 8 nuclear microsatellite loci in 794 individuals from 30 sampling sites.
Results: Two major genetic clusters were identified across the range: a southwestern cluster and a northern cluster. The south-western cluster, which included two subclusters, was bounded approximately by the Continental Divide to the east and the southern extent of the ice sheet at the Last Glacial Maximum to the north. Subclusters were not detected in the northern cluster, despite its continent-wide distribution. Genetic distance was significantly correlated with geographical distance in the south-western but not the northern cluster, and allelic richness was significantly lower in south-western sampling sites compared with northern sampling sites. Population structuring was low overall, but elevated in the south-western cluster.
Main conclusions: Aspen populations in the south-western portion of the range are consistent with expectations for a historically stable edge, with low within-population diversity, significant geographical population structuring, and little evidence of northward expansion. Structuring within the southwestern cluster may result from distinct gene pools separated during the Pleistocene and reunited following glacial retreat, similar to patterns found in other forest tree species in the western USA. In aspen, populations in the southwestern portion of the species range are thought to be at particularly high risk of mortality with climate change. Our findings suggest that these same populations may be disproportionately valuable in terms of both evolutionary potential and conservation value
âMaybe I Made Up the Whole Thingâ: Placebos and Patientsâ Experiences in a Randomized Controlled Trial
Patients in the placebo arms of randomized controlled trials (RCT) often experience positive changes from baseline. While multiple theories concerning such âplacebo effectsâ exist, peculiarly, none has been informed by actual interviews of patients undergoing placebo treatment. Here, we report on a qualitative study (n = 27) embedded within a RCT (n = 262) in patients with irritable bowel syndrome. Besides identical placebo acupuncture treatment in the RCT, the qualitative study patients also received an additional set of interviews at the beginning, midpoint, and end of the trial. Interviews of the 12 qualitative subjects who underwent and completed placebo treatment were transcribed. We found that patients (1) were persistently concerned with whether they were receiving placebo or genuine treatment; (2) almost never endorsed âexpectationâ of improvement but spoke of âhopeâ instead and frequently reported despair; (3) almost all reported improvement ranging from dramatic psychosocial changes to unambiguous, progressive symptom improvement to tentative impressions of benefit; and (4) often worried whether their improvement was due to normal fluctuations or placebo effects. The placebo treatment was a problematic perturbation that provided an opportunity to reconstruct the experiences of the fluctuations of their illness and how it disrupted their everyday life. Immersion in this RCT was a co-mingling of enactment, embodiment and interpretation involving ritual performance and evocative symbols, shifts in bodily sensations, symptoms, mood, daily life behaviors, and social interactions, all accompanied by self-scrutiny and re-appraisal. The placebo effect involved a spectrum of factors and any single theory of placeboâe.g. expectancy, hope, conditioning, anxiety reduction, report bias, symbolic work, narrative and embodimentâprovides an inadequate model to explain its salubrious benefits
Hematopoietic stem and progenitor cells are present in healthy gingiva tissue
Hematopoietic stem cells reside in the bone marrow, where they generate the effector cells that drive immune responses. However, in response to inflammation, some hematopoietic stem and progenitor cells (HSPCs) are recruited to tissue sites and undergo extramedullary hematopoiesis. Contrasting with this paradigm, here we show residence and differentiation of HSPCs in healthy gingiva, a key oral barrier in the absence of overt inflammation. We initially defined a population of gingiva monocytes that could be locally maintained; we subsequently identified not only monocyte progenitors but also diverse HSPCs within the gingiva that could give rise to multiple myeloid lineages. Gingiva HSPCs possessed similar differentiation potentials, reconstitution capabilities, and heterogeneity to bone marrow HSPCs. However, gingival HSPCs responded differently to inflammatory insults, responding to oral but not systemic inflammation. Combined, we highlight a novel pathway of myeloid cell development at a healthy barrier, defining a gingiva-specific HSPC network that supports generation of a proportion of the innate immune cells that police this barrier
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