8,347 research outputs found

    Observation of surface charge screening and Fermi level pinning on a synthetic, boron-doped diamond

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    Spectroscopic current-voltage (I-V) curves taken with a scanning tunneling microscope on a synthetic, boron-doped diamond single crystal indicate that the diamond, boiled in acid and baked to 500 °C in vacuum, does not exhibit ideal Schottky characteristics. These I-V curves taken in ultrahigh vacuum do not fit the traditional theory of thermionic emission; however, the deviation from ideal can be accounted for by charge screening at the diamond surface. At ambient pressure, the I-V curves have a sharp threshold voltage at 1.7 eV above the valence band edge indicating pinning of the Fermi energy. This measurement is in excellent agreement with the 1/3 band gap rule of Mead and Spitzer [Phys. Rev. 134, A713 (1964)]

    Alternatives for Measuring Hazardous Waste Reduction

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    PTI Project number 233U-4913FRHWRIC Project Number 89006

    Optimal Control of Spreading Biological Invasions: For How Long Should We Apply the Brake?

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    Identifying the optimal switching point between different invasive alien species (IAS) management policies is a very complex task and policy makers are in need of modelling tools to assist them. In this paper we develop an optimal control bioeconomic model to estimate the type of optimal policy and switching point of control efforts against a spreading IAS. We apply the models to the case study of Colorado potato beetle in the UK. The results demonstrate that eradication is optimal for small initial sizes of invasion at discovery. High capacity of the agency to reduce spread velocity for several years leads to smaller total overall costs of invasion and makes eradication optimal for larger sizes of initial invasion. In many cases, it is optimal to switch from control to acceptance within the time horizon. The switching point depends on the capacity of the agency, initial size of invasion, spread velocity of the IAS and the ratio of unit cost of damage and removal. We encourage the integration of the dispersal patterns of the invader and the geometry of the invasion in the theoretical development of the economics of IAS invasion management.barrier zone, biosecurity, dynamic optimization, eradication, Leptinotarsa decemlineata, pest risk analysis, reaction-diffusion., Risk and Uncertainty, Q1, Q28, Q57,

    Blunted Cystine–Glutamate Antiporter Function in the Nucleus Accumbens Promotes Cocaine-induced Drug Seeking

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    Repeated cocaine alters glutamate neurotransmission, in part, by reducing cystine–glutamate exchange via system xc−, which maintains glutamate levels and receptor stimulation in the extrasynaptic compartment. In the present study, we undertook two approaches to determine the significance of plasticity involving system xc−. First, we examined whether the cysteine prodrug N-acetylcysteine attenuates cocaine-primed reinstatement by targeting system xc−. Rats were trained to self-administer cocaine (1 mg/kg/200 μl, i.v.) under extended access conditions (6 h/day). After extinction training, cocaine (10 mg/kg, i.p.) primed reinstatement was assessed in rats pretreated with N-acetylcysteine (0–60 mg/kg, i.p.) in the presence or absence of the system xc− inhibitor (S)-4-carboxyphenylglycine (CPG; 0.5 μM; infused into the nucleus accumbens). N-acetylcysteine attenuated cocaine-primed reinstatement, and this effect was reversed by co-administration of CPG. Secondly, we examined whether reduced system xc− activity is necessary for cocaine-primed reinstatement. To do this, we administered N-acetylcysteine (0 or 90 mg/kg, i.p.) prior to 12 daily self-administration sessions (1 mg/kg/200 μl, i.v.; 6 h/day) since this procedure has previously been shown to prevent reduced activity of system xc−. On the reinstatement test day, we then acutely impaired system xc− in some of the rats by infusing CPG (0.5 μM) into the nucleus accumbens. Rats that had received N-acetylcysteine prior to daily self-administration sessions exhibited diminished cocaine-primed reinstatement; this effect was reversed by infusing the cystine–glutamate exchange inhibitor CPG into the nucleus accumbens. Collectively these data establish system xc− in the nucleus accumbens as a key mechanism contributing to cocaine-primed reinstatement

    Physically separating printed circuit boards with a resilient, conductive contact

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    A multi-board module provides high density electronic packaging in which multiple printed circuit boards are stacked. Electrical power, or signals, are conducted between the boards through a resilient contact. One end of the contact is located at a via in the lower circuit board and soldered to a pad near the via. The top surface of the contact rests against a via of the facing printed circuit board

    Anatomy of the binary black hole recoil: A multipolar analysis

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    We present a multipolar analysis of the gravitational recoil computed in recent numerical simulations of binary black hole (BH) coalescence, for both unequal masses and non-zero, non-precessing spins. We show that multipole moments up to and including l=4 are sufficient to accurately reproduce the final recoil velocity (within ~2%) and that only a few dominant modes contribute significantly to it (within ~5%). We describe how the relative amplitudes, and more importantly, the relative phases, of these few modes control the way in which the recoil builds up throughout the inspiral, merger, and ringdown phases. We also find that the numerical results can be reproduced by an ``effective Newtonian'' formula for the multipole moments obtained by replacing the radial separation in the Newtonian formulae with an effective radius computed from the numerical data. Beyond the merger, the numerical results are reproduced by a superposition of three Kerr quasi-normal modes (QNMs). Analytic formulae, obtained by expressing the multipole moments in terms of the fundamental QNMs of a Kerr BH, are able to explain the onset and amount of ``anti-kick'' for each of the simulations. Lastly, we apply this multipolar analysis to help explain the remarkable difference between the amplitudes of planar and non-planar kicks for equal-mass spinning black holes.Comment: 28 pages, 20 figures, submitted to PRD; v2: minor revisions from referee repor

    Repeated \u3cem\u3eN\u3c/em\u3e-Acetylcysteine Administration Alters Plasticity-Dependent Effects of Cocaine

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    Cocaine produces a persistent reduction in cystine–glutamate exchange via system xc− in the nucleus accumbens that may contribute to pathological glutamate signaling linked to addiction. System xc− influences glutamate neurotransmission by maintaining basal, extracellular glutamate in the nucleus accumbens, which, in turn, shapes synaptic activity by stimulating group II metabotropic glutamate autoreceptors. In the present study, we tested the hypothesis that a long-term reduction in system xc− activity is part of the plasticity produced by repeated cocaine that results in the establishment of compulsive drug seeking. To test this, the cysteine prodrug N-acetylcysteine was administered before daily cocaine to determine the impact of increased cystine–glutamate exchange on the development of plasticity-dependent cocaine seeking. Although N-acetylcysteine administered before cocaine did not alter the acute effects of cocaine on self-administration or locomotor activity, it prevented behaviors produced by repeated cocaine including escalation of drug intake, behavioral sensitization, and cocaine-primed reinstatement. Because sensitization or reinstatement was not evident even 2–3 weeks after the last injection of N-acetylcysteine, we examined whether N-acetylcysteine administered before daily cocaine also prevented the persistent reduction in system xc− activity produced by repeated cocaine. Interestingly, N-acetylcysteine pretreatment prevented cocaine-induced changes in [35S]cystine transport via system xc−, basal glutamate, and cocaine-evoked glutamate in the nucleus accumbens when assessed at least 3 weeks after the last N-acetylcysteine pretreatment. These findings indicate that N-acetylcysteine selectively alters plasticity-dependent behaviors and that normal system xc− activity prevents pathological changes in extracellular glutamate that may be necessary for compulsive drug seeking

    Notes on Euclidean Wilson loops and Riemann Theta functions

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    The AdS/CFT correspondence relates Wilson loops in N=4 SYM theory to minimal area surfaces in AdS5 space. In this paper we consider the case of Euclidean flat Wilson loops which are related to minimal area surfaces in Euclidean AdS3 space. Using known mathematical results for such minimal area surfaces we describe an infinite parameter family of analytic solutions for closed Wilson loops. The solutions are given in terms of Riemann theta functions and the validity of the equations of motion is proven based on the trisecant identity. The world-sheet has the topology of a disk and the renormalized area is written as a finite, one-dimensional contour integral over the world-sheet boundary. An example is discussed in detail with plots of the corresponding surfaces. Further, for each Wilson loops we explicitly construct a one parameter family of deformations that preserve the area. The parameter is the so called spectral parameter. Finally, for genus three we find a map between these Wilson loops and closed curves inside the Riemann surface.Comment: 35 pages, 7 figures, pdflatex. V2: References added. Typos corrected. Some points clarifie

    Modeling kicks from the merger of generic black-hole binaries

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    Recent numerical relativistic results demonstrate that the merger of comparable-mass spinning black holes has a maximum ``recoil kick'' of up to \sim 4000 \kms. However the scaling of these recoil velocities with mass ratio is poorly understood. We present new runs showing that the maximum possible kick perpendicular to the orbital plane does not scale as η2\sim\eta^2 (where η\eta is the symmetric mass ratio), as previously proposed, but is more consistent with η3\sim\eta^3, at least for systems with low orbital precession. We discuss the effect of this dependence on galactic ejection scenarios and retention of intermediate-mass black holes in globular clusters.Comment: 5 pages, 1 figure, 3 tables. Version published in Astrophys. J. Let
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