5 research outputs found
Impact of opioid-free analgesia on pain severity and patient satisfaction after discharge from surgery: multispecialty, prospective cohort study in 25 countries
- Author
- Aamir Faiqa Binte
- Aamir Syed Roohan
- Ababneh Adnan
- Abbal Muhammad Anas
- Abbas Ahmed M
- Abbas Mostafa
- Abd-Albain Montasir A
- Abdalei Abdulwahab
- Abdalla Ahmed
- Abdalla Ahmed Yassir
- Abdalla Mohamed Galal Ali
- Abdalla Zainab
- Abdallah Mohamed M
- Abdalmahmoud Noon Ezzeldien
- Abdalsadeg Rowa
- Abdelaal Ahmed M
- Abdelbagi Alnazeer Y
- Abdelbaky Mostafa
- Abdelbaset Doaa
- AbdElbaset Esraa
- Abdelbast Menhag
- Abdelfatah Mohammed Abdelnasser
- Abdelgawad Samia
- Abdelhamid Mohamed M
- Abdeljaber Mahmoud
- Abdelkhalig Mubarak
- Abdelmaksoud Mohamed
- Abdelmeguid Rana
- Abdelmelek Dhia Errahmane
- Abdelnaeam Samah
- Abdelnasser Mohammad K
- Abdelrahim Najwa
- Abdelrahman Amira
- Abdelrahman Ayman
- Abdelsalam Hebatalla
- Abdelsamed Enas Abdelbaset
- Abdelwahab Khaled
- Abdoun Meriem
- Abdulali Fatima
- Abdulaziz Mohamed
- Abdulla Dheba Almukhtar
- Abdullah Bahiyah
- Abdullah Bahiyah
- Abdullah Walaa
- Abdullahi Habiba Ibrahim
- Abdulrahman Ahmed
- Abdulrasheed Lubabatu
- Abdulwahed Eman
- Abdulwahed Eman
- Abeysirigunawardana Dewmi
- Abidin Muhammad Fihmi Zainal
- Abiola Olukayode
- Abiyere Henry
- Abodina Ahmed Mohammed
- Aboelela Reham
- AboElfarh Hadeer Elsaeed
- Aboudlal Husein
- AbouHiekal Osama
- Aboulfotouh Ahmed
- Abozid Anwaar
- Abubaker Noora
- Abubaker Noora
- Abufanas Asma
- Abughanima Mahmoud
- Abuhashem Shehab
- Abulafia Daniel
- Abushaala Fatima
- Abushanab Khaled
- AbuShawareb Issa
- Abuuqteish Hamza
- Abuzaho Amany
- Achem Arome
- Adam Eithar
- Adam Mohammed
- Adam Mohammed A
- Addalla Mohamed
- Addley Jordan
- Adeleye Gbadebo
- Adeniyi Adebayo
- Adewole Nathaniel
- Adeyemo Olabisi
- Adeyeye Ademola
- Adeyeye Ademola
- Adly Michael
- Adnan Siti Nasyirah Nisya
- Ads Adel Mohamed
- Ads Alaa Mohamed
- Adze Joel Amwe
- Afeikhena Ehis
- Agida Teddy
- Agilla Hamza
- Agnew Emilie
- Agu Joy Onyekachi
- Ahmad Zatul Akmar
- Ahmed Abdalla
- Ahmed Ahmed
- Ahmed Ahmed
- Ahmed Alaaaldeen
- Ahmed Entisar
- Ahmed Habeeba
- Ahmed Hatem
- Ahmed Reem
- Ahmed Rehab
- Ahmed Rihab
- Ahmed Rogia Ahmed Abdalla
- Ahmed Ruaa
- Ahmed Sharwany
- Ahmed Uzair
- Ahmed Wahiba
- Ahmeed Sultan
- Airede Lydia Regina
- Aitchison Lori
- Ajredini Mirac
- Ajulo Adeshina A
- Akaba Godwin
- Akasha Mazin
- Akbar Maha Ghulam
- Akbuz Seyma Orcan
- Akdere Hakan
- Akın Bilge
- Akkaya Ege Nur
- Akpamgbo Chukwunonso Nnamdi
- Akwaisah Ayoub
- Al Hammoud Amr
- Al Rawashdeh Toka
- Al-Baw Mahmoud
- Al-Dahdouh Mosheer
- Al-Haek Safa’
- Al-Hazaimeh Mo'ath
- Al-issawi Dima
- Al-Issawi Subhi
- Al-jammal Maryam
- Al-Juaifari Maytham A
- Al-Mwajeh Tesneem
- Al-Omary Sohaib
- Al-Quossi Mohammed
- Al-Shambaty Yasir Babkir Ali
- Al-Shami Qotadah
- Al-Smirat Heba
- Al-Tahayneh Sief-Addeen
- Al-Touny Aiman
- Al-Touny Shimaa
- Al-zawaydeh Alia
- Alaa Ali
- Alabed Ebtihal
- Alagelli Fatma
- Alagoz Ahmet Can
- Alameen Hind
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- Alaqoubi Retaj
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- Alariby Fatima
- Alatefi Dawood
- Alathameen Nassar
- Albakosh Bashir Abobaker
- Albanopoulos Konstantinos
- Albarhomy Osama
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- Alboon Mosab
- Alboridy Muneera
- Alboueishi Asraa Ali
- Aldeges Marwan
- Aldreawi Mohammed
- Alflite Asil Omar Saleh
- Alfrijat Tamam
- Alfrjani Tariq
- Algabbasi Salima
- Algatanesh Nassib
- Alhadad Qamrah
- Alhaddad Hoda Salem
- Alhaleem Ayah
- Alhaleeq Saif
- Alharam Abtisam
- Alhashimi Abdulhadi Mohammed Alhadi
- Alhassan Monzer
- Alhudhairy Sara
- Ali Ahmed
- Ali Aml
- Ali Doua
- Ali Eithar M
- Ali Iqra Fatima Munawar
- Ali Maab
- Ali Manal
- Ali Muhammad
- Ali Radwa
- Ali Rawan Alsheikh
- Ali Rzan Ali Hamedelneel
- Ali Shehroz
- Aliosin Oleg
- Aljamal Mohammad
- Aljamal Sarah
- Alkaraja Layth
- Alkaseek Akram
- Alkazali Mustafa
- Alkchr Hayat Ben Hasan Mohamed A A
- Alkhatib Abed Alazeez
- Allam Shereen
- Almahroush Marin
- Almakki Doha Mohammed Ahmed
- Alnajjar Lara
- Alnajjar Majjd
- Alnatsheh Wesam
- Alnour Ammar
- Alomar Rabiaa
- Alomari Yazan
- Alqaarh Aya
- Alragig Zahra
- Alrifae Ghaliya Mohamed H
- Alrosan Risan
- Alsagoff Sharifah Nor Amirah Syed Abdul Latiff
- Alsaid Hamza
- Alsaify Esmat
- Alsaih Sawsan
- Alsari Najah
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- Alshawadfy Abdelrhman
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- Alsheik Ahmad
- Alsori Mohamed
- Alsoudani Ali
- Altabbaa Hashem
- Altahir Mohamed
- Altair Mawadda
- Altaweel Ahmad
- Altughar Bushra
- Alvarez Matias
- Alvarez-Lozada Luis Adrian
- Alvarez-Lozada Luis Adrian
- Alwahaib Anas
- Alwash Mohammed
- Alzarga Ali
- Alzarouq Ebtisam
- Alzarroug Amal
- Alzghoul Bader
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- Amarasekara Mishka
- Amary Marwa
- Ametov Amet
- Amin Mostafa K
- Aminu Bashiru
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- Ammar Ahmed Siddique
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- Lee Christine
- Lee Jennifer
- Lee Jouyee
- Lee Melissa
- Leeson Hilary
- Legge-Wilkinson Hannah
- Lemdaoui Naoual
- Lemhaishi Alzahra
- Leow San-Hui Anita
- Lescheid Jonathan
- Leung Edmund
- Lew Chen
- Li Andrea
- Li Andy
- Li Damon
- Li Jiting
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- Lightfoot Nicholas
- Lim Janice
- Lim Jennifer
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- Liu David
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- Liu Gordon
- Liu Gordon
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- Maged Bassant Maged
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- Palaniappan Ramanathan Rm
- Pang Siyuan
- Pantoja Maria Alejandra Nanez
- Papanikolaou Evangelos
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- Park Melissa
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- Patel Diya
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- Patil Aditya
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- Paul Rohit
- Pearce Liam
- Pegorer Amanda Gonzalez
- Pehlivan Dilan
- Peker Joshua
- Penneru Sai Harshitha
- Pereira Ashley
- Pesce Antonio
- Peters Luke
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- Pham Andrew
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- Pilgrim Charles
- Pillai Anil Kumar Sree Kumar
- Pockney Peter
- Pockney Peter
- Podder Nayanika
- Polat Süleyman
- Polo Samantha
- Pothukuchi Prasanna
- Pottier Mark
- Pozzi Isabella
- Prasad Shaamnil
- Prasad Shalvin
- Prinsloo Duron
- Proud David
- Qattawi Taima’
- Qazi Arisha
- Qian Gemma
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- Quadros Dwain
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- Quinlan Liam
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- Rae Hamish
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- Rais Mounira
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- Rajesh Krishnankutty
- Raji Hadijat Olaide
- Ramadan Mohamed
- Ramadan Mohamed F
- Ramlee Afiq Aizat
- Ramphal Shanay
- Rashed Osama Fathy Ali Ali
- Rasheed Ayat
- Raslan Bassma
- Rasslan Esraa
- Rathnayake Athulya
- Ratnayake Milidu
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- Raubenheimer Kyle
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- Rauf Abdul
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- Razmi Akeedh
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- Rehfisch Peter
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- Rosello-Añon Alejandro
- Roshdy Mo'men
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- Rusli Siti Mayuha
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- Saad Mahmoud M
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- Sabuncu Kubilay
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- Salameh Alaa Eddin
- Salawu Adedayo
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- Saleh Sara Ahmed
- Salem Ebrahim
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- Saliaris Konstantinos
- Salih Alaa A
- Salihu Makama Baje
- Sallam Abdelaziz
- Samalavicius Narimantas
- Sami Wesam
- Sammour Tarik
- Sampatha-Waduge Tharushi
- Sanad Aly
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- Sanguesa Maria Jose
- Sani Samuel Ali
- Sanli Ahmet Necati
- Sanz-Romera Jorge
- Sara Rachel
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- Sarafi Aikaterini
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- Sarih Monira
- Sarwar Albash
- Sathasivam Vinogi
- Sathiyaseelan Avinash
- Sawaftah Khaled
- Sayed Ahmed M
- Sayed Mohamed Al
- Sayed Yasmeen
- Saylar Alparslan
- Saylar Alparslan
- Sánchez Luis Antonio Heredia
- Schizas Dimitrios
- Segaran Sharrada
- Seldon Alexandra
- Selim Kamar
- Selim Osama
- Seneviratne Dharani
- Sengupta Shomik
- Senthilrajan Rahavi
- Seow Warren
- Shaaban Abdelrahman
- Shaban Aya
- Shaban Walid
- Shabaneh Amin
- Shafaat Amna
- Shagroun Esra
- Shah Jainil
- Shah Jainil
- Shahat Mohammed A
- Shaheen Nourhan
- Shahin Mahmoud
- Shalaby Mostafa
- Shalalfeh Sa'ed
- Shaltout Asmaa S
- Shamshoon Kerollos
- Shanag Hadeel
- Shanahan James
- Shang Mengge
- Shannaq Rabab
- Shaqran Osama Al
- Sharma Sonakshi
- Sharp James
- Shaw Haylee
- Shaw Henry
- Shehab Ali Fahmy
- Shehahda Sireen
- Shehata Mena
- Shen Yijia
- Sherif Yara
- Sheriff Arfaan
- Shetwan Sundes
- Shipa Ahmed
- Shiru Mariam Motunrayo
- Shrestha Pallavi
- Shuaibu Ibrahim Shaphat
- Shui Amanda
- Sibic Osman
- Sierra Oscar Alonso Verduzco
- Silem Yousra Othman Reham
- Silva Yannick De
- Silverii Julia
- Simiona Levi
- Simonetti Marta
- Singer David
- Singh Abhinav
- Singh Gopal
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- Singh Madhavi
- Singh Ramnik
- Singh Surya
- Singh Surya
- Singhal Megan
- Sinha Akansha
- Siribaddana Venesa
- Sivakumar Gananadha
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- Sivasuthan Goutham
- Sivrikaya Ramazan Kemal
- Skalidou Smaragda
- Skoufias Spyridon
- Slavec Mark
- Smadi Rayyan
- Smith Corinne
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- Smith Quintin
- Smitham Peter
- Snider Ruth
- Sobhy George
- Soek Jenny
- Sofian Ahmad Anuar
- Soh Isabel
- Soh Jien Yen
- Soh Qi Rui
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- Sok Rumnea
- Sokmen Selman
- Solagbade Remi Sanyaolu
- Solanki Krisha
- Solar Caitlin Del
- Soliman Keroles
- Soliman Mahmoud Ayman
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- Soltan Hatem
- Songden Zumnan
- Soni Akshay
- Soula Enas
- Soytas Mustafa
- Sriranjan Roshni
- Sritharan Mithra
- Srivastava Shambhavi
- Standish Lucy
- Stavratis Fotios
- Stevens Sean
- Stewart Peter
- Stokes Andrew
- Struthers Jamie
- Studd Rod
- Sulaiman Bilal
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- Suliman Merna Ezz
- Sun Kexin
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- Surkitt Amy
- Suttor Sean
- Swalem Aisha
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- Syed Saifulla
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- Tabak Elif Zeynep
- Taha Hala Abdelhalim Mohamed
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- Tahir Farah
- Tahir Izza
- Taingson Mathew Chum
- Talaat Omnia
- Talavera Elena
- Taman Mohamed
- Tan Kevin
- Tan Sarah
- Tan Sarah
- Tan Suqi
- Tan Wen Po Jonathan
- Tandogan Yusuf Iskender
- Tang Howard
- Tang Patrick
- Tang-Ieam Pattarapan
- Tao Steve
- Tarek Yousef
- Tariq
- Tarmidi Jazmina
- Tasi Zoya
- Taşcı Muhammed Enes
- Taufiq Maliha
- Tay Kai Yun Jodene
- Taylor Emily
- Taylor Isobel
- Teema Eman
- Telci Hatice
- Temerik Abdallah Rashad
- Teng Cherilyn
- Tepe Mustafa Deniz
- Tepe Mustafa Deniz
- Terrosu Giovanni
- Theophilus Mary
- Thompson Nasya
- Thornton-Hume David
- Tiffany Lea
- Ting Clarissa
- Tiras Hale Nur
- Titan Ashley
- Toft Alexandra
- Traina Francesco
- Tran Anthony
- Tran Quang
- Tran Tam
- Tran Will
- Trotta Georgina
- Tsakiridis Ioannis
- Tsakiridis Nikolaos
- Tsourouflis Gerasimos
- Tsui Sonia Ching Ting
- Tu Hien
- Tun Than
- Tung Melody
- Tuzuner Filiz
- Tynan Dominic
- Ugool Mahmoud
- Uğurlu Mustafa Ümit
- Ukrani Ronika Devi
- Ukwuoma Ohia Ernest
- Ulkucu Attila
- Uludag Server Sezgin
- Ulusahin Mehmet
- umar Abubakar
- Umar Gabi Ibrahim
- Uprak Tevfik Kıvılcım
- Ureña Violeta
- Usman Liman Haruna
- Uyanık Mustafa Safa
- Uzair Ahmad
- Uzel Kadir
- Vadioaloo Dinesh Kumar
- Valaroutsou Olga Maria
- Valverde-Vazquez Rocio
- Vance Lucille
- Vanguardia Kristina
- Vanguardia Maria Kristina
- Vanzuylekom Katie
- Varesano Marco
- Varghese Chris
- Varghese Chris
- Velenciuc Natalia
- Vermeulen Wikus
- Vidanagama Sasini
- Vimalan Vineeth
- Virani Sehar Salim
- Vollenhoven Beverley
- Vong Crystal
- Vrakopoulou Gavriella Zoi
- Vu Jennifer
- Vu Jennifer
- Waaka Nicholas
- Wadhwa Sanya
- Wagaarachchi Prabhath
- Waheed Ayesha Akbar
- Waldin Lucy
- Walsh Eamon
- Walters Chris
- Wang Bill
- Wang Christine
- Wang Erica
- Wang Grace
- Wang Katie
- Wang Nicole Qiwen
- Wang Pengnan
- Wang Qiwen
- Wang Shelley
- Wang Yantong
- Wang Zixuan
- Waqar Usama
- Waraich Abdullah
- Ward Jack
- Wardeh Salah Abu
- Wasim Tayyiba
- Watson David
- Watson David
- Wedatalla Mansour
- Weeda Lewis
- Wells Cameron
- Wells Cameron
- Wells Cameron
- Wells Oliver
- Werenski Hope
- Wijayaratne Rivindu
- Wijetunga Asanka
- Williams Brittany
- Williams Peter
- Wilson Thomas
- Windsor John
- Windsor John
- Winthrop Lily
- Withanage Indrajith
- Wong James
- Wong Jason
- Wong Kenneth
- Wong King Ho
- Wong Patrick
- Wong Samantha
- Woodbridge Christian
- Wright Deborah
- Wright Deborah
- Wright Deborah
- Wu Alan
- Wu Alan
- Wu Chun-Yen
- Wu Hongyi
- Wycliff Daniel
- Xiao Haotian
- Xie Maria
- Xu Cindy
- Xu William
- Xu William
- Xu William
- Yaghmour Jamal
- Yahya Bilal Shuaibu
- Yahya Rawad
- Yang Wah
- Yao Michelle
- Yao Sunny
- Yao Sunny
- Yasar Meltem
- Yasir Ruaa
- Yassin Mohamed
- Yavuz Dogancan
- Yavuz Ikranur
- Yaytokgil Muhammet
- Yazgan Yasemin
- Yee Su-Ann
- Yeung Justin
- Yeung Kar Long
- Yew Anthea
- Yi Kevin
- Yiannakopoulos Christos
- Yildirim Yasemin
- Yildiz Ahmet
- Yıldız Berkay
- Yilmaz Hakan
- Yin Chonghao
- Ying Geoffrey
- Yodkitydomying Chatnapa
- Yong Nathania
- Yoon Si Woo
- You Ha Seong
- Young Simon
- Young Stevie
- Younus Khadijah
- Yousif Fatima Imad
- Yousri Mohamed
- Youssef Ahmed A
- Youssef Arkan
- Yu Hoi Hang
- Yu Victor
- Yuan Grace
- Yue Bosco
- Yue Tiffany
- Yunos Mohamed Haseef Mohamed
- Yusuf Stephen
- Yuzgec Ayse Nilufer
- Zachomitros Fotios
- Zaed Moahmed
- Zafar Fatima
- Zaghloul Ahmed
- Zaheer Adil
- Zaidi Faseeh
- Zain Ahmad
- Zakaria Ahmed
- Zakaria Andee Dzulkarnaen
- Zakaria Mohd Zaim
- Zalloum Jihad
- Zamanbandhon Bushra
- Zambon Mattia
- Zapsalis Konstantinos
- Zargar Kamran
- Zarzour Mohamed A
- Zeng Raymond
- Zeng Raymond
- Zengin Kagan
- Zertuche Juventino Tadeo Guerrero
- Zhang Caitlin
- Zhang Edward
- Zhang Shane
- Zhang Yichi
- Zhao Hailin
- Zheng Helen
- Zhou Karen
- Zhou Yida
- Ziergiebel Felix
- Zou Peishan
- Zuylekom Kate Van
- Zuylekom Katie Van
- Zwain Yasir Adnan
- Zyul'korneeva Sof'ya
- Aladna Abdallah
- Aljoumaa Abdullah
- Nawfal Hamdi
- Niazi Ammar
- Publication venue
- Publication date
- 01/01/2024
- Field of study
Background: Balancing opioid stewardship and the need for adequate analgesia following discharge after surgery is challenging. This study aimed to compare the outcomes for patients discharged with opioid versus opioid-free analgesia after common surgical procedures.Methods: This international, multicentre, prospective cohort study collected data from patients undergoing common acute and elective general surgical, urological, gynaecological, and orthopaedic procedures. The primary outcomes were patient-reported time in severe pain measured on a numerical analogue scale from 0 to 100% and patient-reported satisfaction with pain relief during the first week following discharge. Data were collected by in-hospital chart review and patient telephone interview 1 week after discharge.Results: The study recruited 4273 patients from 144 centres in 25 countries; 1311 patients (30.7%) were prescribed opioid analgesia at discharge. Patients reported being in severe pain for 10 (i.q.r. 1-30)% of the first week after discharge and rated satisfaction with analgesia as 90 (i.q.r. 80-100) of 100. After adjustment for confounders, opioid analgesia on discharge was independently associated with increased pain severity (risk ratio 1.52, 95% c.i. 1.31 to 1.76; P < 0.001) and re-presentation to healthcare providers owing to side-effects of medication (OR 2.38, 95% c.i. 1.36 to 4.17; P = 0.004), but not with satisfaction with analgesia (beta coefficient 0.92, 95% c.i. -1.52 to 3.36; P = 0.468) compared with opioid-free analgesia. Although opioid prescribing varied greatly between high-income and low- and middle-income countries, patient-reported outcomes did not.Conclusion: Opioid analgesia prescription on surgical discharge is associated with a higher risk of re-presentation owing to side-effects of medication and increased patient-reported pain, but not with changes in patient-reported satisfaction. Opioid-free discharge analgesia should be adopted routinely
Older Adults' Out-of-home Activities in a Super-aged High-rise, High-density Neighborhood: A Qualitative Study
- Publication venue
- 'Informa UK Limited'
- Publication date
- 10/04/2023
- Field of study
Journal of Aging and Environment371100-12
Using Walk-Along Interviews to Identify Environmental Factors Influencing Older Adults’ Out-of-Home Behaviors in a High-Rise, High-Density Neighborhood
- Author
- Publication venue
- 'MDPI AG'
- Publication date
- Field of study
Malaysia and Singapore 1990-1993
- Author
- Abraham Susan
- Ahmad Shahnon
- Alice Pillay
- Aljafri Syed Adam
- Aljafri Syed Adam
- Alwi Syed
- Alwi Syed
- Ambrase Aban
- Amin Fadzilah
- Anderson Joan
- Angeline Teo
- Annie Greet
- Anwar Ridhwan
- Awang Usman
- Awang Usman
- Azhari Che Husna
- Azizah Kassim
- Baratham Gopal
- Ben Joned
- Ben Joned Salleh
- Bloodworth Dennis
- Bonnivier Kalifa
- Brazil David
- Caddy Florence
- Cameron Ming
- Chan Joon Yee
- Chan Joon Yee
- Chan Leslie
- Chan Meng Yin
- Checkets Susanna
- Chee Soon Lian
- Cheung Phei
- Chew Shirley
- Chiang Michael
- Chin Edna
- Chin Woon Ping
- Christopher Holmes
- Chua Amy
- Chuah Guat
- Dale Spender
- de Cruz Gerald
- de Cruz Gerald
- De Souza Dudley
- Delia Paul
- Donald Jimmy
- Dorothy Colmer
- E.N. Dorall
- Eddie Khoo
- Edward Dorrall
- Elizabeth Chong
- Eng Wee
- Ezekiel Nissim
- Fauconnier Henri
- Fernandez Shalini
- Fernando Lloyd
- Fernando Lloyd
- Fuhrmann-Lim David
- Fuhrmann-Lim Gary
- Fung Jojo M.
- Gan Teik Chee
- Gaudart Hyacinth
- Gaudart Hyacinth
- Gay Jenny
- Goh Sin
- Goh Sin Tub
- Gopal Baratham A.
- Hamilton-Shimmen Wilfred
- Harry Aveling
- Hassan Noordin
- Hassan Noordin
- Heng Siok
- Heng Siok Tian
- Hew M.K.
- Hickling Hugh
- Hicks Bonny
- Ho Liyen
- Hui Joshua
- Imogen Smith
- Ismail Ghazally
- Ismail Mohamad
- Ismail Siti Zainon
- Jacqueline Lo
- Jacqueline Lo
- Jayapal Maya
- Jeyam Leonard
- Johan Jaffar
- Johari Mohamed
- Joseph Jeyakumar
- Julie Chatterjee
- Kahar Baharuddin
- Kamaluddin Latif
- Karmakar Basanti
- Kasinathan K Ganesan
- Kee Thuan
- Kee Thuan Chye
- Kemala
- Keppel Henry
- Keppel Henry
- Keris Mas
- Khoo Catherine
- Khoo Jonathan
- Kiat Xavier
- Killingley Siew-Yue
- King Victor T.
- Koh Buck Song
- Koh Buck Song
- Koh Buck Song
- Koh Buck Song
- Koh Buck Song
- Koh Buck Song
- Koh Tai
- Koh Buck Song
- Koh Tien
- Kon Stella
- Kuo Pao
- Lau Shirley
- Lau Siew Mei
- Le Goh Jimmie
- Lee
- Lee Tzu Pheng
- Lee Charlie
- Lee Douglas
- Lee Johann S
- Lee John Joo-For
- Lee Jonathan
- Lee Kok Liang
- Lee Russell
- Lee Tzu Pheng
- LeGoh Jimmie
- Leo David
- Lewis G.E.D.
- Liao San China
- Lim Chee Seng
- Lim Chee Seng
- Lim Chee Seng
- Lim Suchen
- Lim Yin Foong
- Lim Catherine
- Lim Catherine
- Lim Christine Suchen
- Lim Swee
- Lim Thean
- Lisa Chua
- Lloyd Fernando
- Loh Chieu
- Louis Marie Gerrina
- Lumholtz Carl
- Maniam K.S.
- Maniam K.S.
- Maniam K.S.
- Maniam K.S.
- Margaret Yong
- Margaret Yong
- Margaret Yong
- Margaret Yong
- McNeely Jeffery
- Michael Lim
- Moey Nicky
- Mohd Taib
- Mohidin Latiff
- Moo Z.Y.
- Ong Henry
- Ong Ivy Ai Bee
- Orville
- Ovidia Yu
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Empagliflozin in Patients with Chronic Kidney Disease
- Author
- Aamir Navivala
- Abdulwahab Arbi
- Abegail Hernandez Pena
- Abraham Hanburry
- Adedolapo Adeleke
- Adeera Levin
- Adil Hazara
- Adline Ghazi
- Agnes Masengu
- Ahmad Tuffaha
- Ahmed Awad
- Ahmed Ghanem
- Ai Fukasawa
- Aik Kheng Lee
- Aiko Terakawa
- Aiko Tomita
- Aiko Yamada
- Ailsa Geddes
- Airi Sato
- Akane Katanosaka
- Akane Yamamoto
- Akihiro Fujimoto
- Akihiro Katayama
- Akihito Tanaka
- Akiko Fujita
- Akiko Hashimoto
- Akiko Ishiguro
- Akiko Omata
- Akimasa Asai
- Akinwande Akinfolarin
- Akio Kanazawa
- Akiyo Nishiyama
- Akiyo Tanabe
- Alastair Rankin
- Alastair Woodman
- Albert Hing
- Albert Power
- Alberto Rosati
- Aldo P Maggioni
- Aldo Peixoto
- Aleksandra Murawska
- Alessandro D'Amelio
- Alex Aguilera
- Alex Baxter
- Alex Howson
- Alexa Wonnacott
- Alexander Hadley
- Alexander Hodakowski
- Alexander Paliege
- Alexis Africano
- Alexis Stevenson
- Alfio Giuffrida
- Alfred K Cheung
- Alia Hasan
- Alia Zubaidah Bahtar
- Alice Aitken
- Alice Guerini
- Aliseiya Garza
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- Alison Jenkins
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- Allen Young
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- Amanda Axler
- Amanda Davis
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- Amber Hurst
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- Amin Oomatia
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- Sina Rolfsmeier
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- Siti Nabilah Mohamad Zaini
- Smeeta Sinha
- Smita Gunda
- Sodai Kubota
- Sofia Dayi
- Sonja Grotjahn
- Sonoka Yamamoto
- Soo Kun Lim
- Soon Yi Sor
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- Sri Yarlagadda
- Sridhar Ramanaidu
- Srinivasan Beddhu
- Stacey-Ann Villaruel
- Stacie Hitchcock
- Stacy Gillham
- Staplin Natalie
- Stefan Degenhardt
- Stefan Haack
- Stefan Hantel
- Stefanie Jones
- Stefanie Kuhn
- Stephan Matthias
- Stephanie Bolton
- Stephanie Estcourt
- Stephanie Evans
- Stephanie Martinez
- Stephanie Rosenberg
- Stephanie Watson
- Stephanie Whittaker
- Stephany Topping
- Stephen Aronoff
- Steubl Dominik
- Steven Nagelberg
- Stevens Will
- Stewart Moffat
- Subash Somalanka
- Subha Clarke
- Subrata Debnath
- Sucharit Joshi
- Sue Ann Lee
- Sue Hewins
- SueAnn Squyres
- Sui Phin Kon
- Sunil Bhandari
- Sunita Bavanandan
- Suresh Ramadoss
- Suria Junus
- Susan Haskett
- Susan Hurley
- Susan McLaughlin
- Susannah Pajak
- Susanne Bodine
- Susanne Brenner
- Susumu Nakatani
- Suzannah Dorey
- Sybille Merscher
- Tabbatha Duck
- Tabinda Dugal
- Tadahiro Tomita
- Taeko Uchida
- Tai Meng Chen
- Takahiro Ishikawa
- Takahiro Kato
- Takahiro Matsunaga
- Takahiro Yamano
- Takako Kuramae
- Takako Ozawa
- Takanori Hyo
- Takashi Funayama
- Takashi Kadowaki
- Takashi Kobayashi
- Takashi Udagawa
- Takatoshi Otani
- Takayuki Katsuno
- Takehiko Wada
- Takehiro Sugiyama
- Takeshi Kurose
- Takeshi Miyatsuka
- Takeshi Ogihara
- Takuji Ishimoto
- Takuma Kojo
- Takuya Haraguchi
- Takuya Yokoyama
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- Tamara Isakova
- Tammi Glider
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- The EMPA-KIDNEY Collaborative Group: Colin Baigent
- Theresa McCarthy
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- Tomohito Izumi
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- Tomoko Hisatake
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- Tomoko Takahashi
- Tomoko Takai
- Tomonori Hasegawa
- Tomoya Mita
- Torsten Schramm
- Toru Ikeda
- Toshiki Kano
- Toshimasa Yamauchi
- Toshiya Yamamoto
- Toshiyuki Komiya
- Toyoyoshi Uchida
- Tracey Cummins
- Tracy Fuller
- Tracy Spinola
- Trevor Greene
- Tricia Young
- Tristan Daniels
- Tsukasa Iwakura
- Tuttle Katherine R
- Tze Jian Ng
- Ulla Ludwig
- Ulrike Giebeln-Hudnell
- Ulrike Schmidt
- Urs Benck
- Ursula Hohenstatt
- Usah Lilavivat
- Vahid Mahabadi
- Vanessa Rivers
- Verlaine Stewart-Ray
- Veronica Poma
- Veronica Yousif
- Vesta Lai
- Vicki Adell
- Vicki Brindle
- Vicki Dodds
- Vicki Donley
- Vickie Jones
- Victoria Carnall
- Victoria Gonce
- Vimal Derebail
- Vinay Varad
- Vittorio Ortalda
- Vivian Yiu
- Vladimir Cejka
- Volker Schettler
- Volker Vielhauer
- Wael Eid
- Wagdy Basily
- Wakako Isari
- Wallendszus Karl
- Waltraud Kmietschak
- Wan Ahmad Faizal Alaidin Razali
- Wan Hazlina Wan Mohamad
- Wanner Christoph
- Waqar Ayub
- Waseem Karsan
- Wasim Deeb
- Wasim Hanif
- Wataru Ogawa
- Wei Wang
- Wei Wei
- Weijing Bian
- Weiping Hou
- Weixin Kong
- Wen Jiun Liu
- Wen Liu
- Wendy Arriaga
- Wiebke Kaluza-Schilling
- Will Stevens
- William Durham
- William G Herrington
- William G Herrington
- William Hodge
- William Petchey
- Wolf-Adam Seeger
- Wolfgang Seeger
- Wuhanbilige Hundei
- Xavier Rossello
- Xia Song
- Xiangcheng Xiao
- Xiaojing Jiao
- Xiaojue Li
- Xiaoliang Wang
- Xinzhou Zhang
- Xiumei Hu
- Xuejiao Liu
- Xueying Wang
- Yan Li
- Yanmei Xu
- Yanping Wang
- YanRu Qiao
- Yanwu Yu
- Yanyun Xie
- Yao Weng
- Yao Yao
- Yasemin Kavak
- Yasuhiko Furukawa
- Yasuhiko Ito
- Yasuhiko Kanaguchi
- Yasuhiro Suzuki
- Yasushi Iwaita
- Ye Mun Low
- Yee Yan Lee
- Yew Fong Liew
- Yi Loon Tye
- Yik Hong Wong
- Yik Shen Lim
- Ying Hu
- Ying Jiang
- Ying Kuan
- Ying Lu
- Yinghua Chen
- Yohei Ejima
- Yoko Inukai
- Yolanda Miller
- Yong Chieh Chan
- Yonghong Bu
- Yoshiaki Morishita
- Yoshie Shibata
- Yoshifumi Tamura
- Yoshihiko Yamasaki
- Yoshihisa Wada
- Yoshikazu Tamori
- Yoshiki Suzuki
- Yoshimitsu Yamasaki
- Yoshinari Yasuda
- Yoshinori Osaki
- Yoshiro Kato
- Yoshiyuki Hamamoto
- Yosuke Hirakawa
- Yosuke Nakagawa
- Youcef Mostefai
- Young Lee-Barkey
- Yu An
- Yu Chen
- Yu Chen Ong
- Yu Yamanouchi
- Yuana Mohd Yusoff
- Yuichiro Munakata
- Yuji Oe
- Yuka Sato
- Yuka Ueda
- Yukari Miura
- Yuki Fujita
- Yuki Fukao
- Yuki Omori
- Yukihiro Shimizu
- Yukihiro Yamaji
- Yukiko Nakayama
- Yukiko Toyonaga
- Yukiko Wakita
- Yuko Katsuda
- Yuko Makita
- Yuko Okada
- Yuko Orimo
- Yumi Osawa
- Yushi Hirota
- Yusuke Suzuki
- Yutaka Kamimura
- Yuya Nishida
- Yvette Webley
- Yvonne Ehrl
- Yvonne Jackson
- Zabrina Lozon
- Zaid Azhari
- Zaiha Harun
- Zainab Sheriff
- Zanaida Cooper
- Zay Htet
- Zhang Duan Tham
- Zhi-Hong Liu
- Zhirui Zhao
- Zhu Doreen
- Zhuo Tang
- Zohreh Forghani
- Zuber Patel
- Publication venue
- 'Massachusetts Medical Society'
- Publication date
- 01/01/2023
- Field of study
Background The effects of empagliflozin in patients with chronic kidney disease who are at risk for disease progression are not well understood. The EMPA-KIDNEY trial was designed to assess the effects of treatment with empagliflozin in a broad range of such patients. Methods We enrolled patients with chronic kidney disease who had an estimated glomerular filtration rate (eGFR) of at least 20 but less than 45 ml per minute per 1.73 m(2) of body-surface area, or who had an eGFR of at least 45 but less than 90 ml per minute per 1.73 m(2) with a urinary albumin-to-creatinine ratio (with albumin measured in milligrams and creatinine measured in grams) of at least 200. Patients were randomly assigned to receive empagliflozin (10 mg once daily) or matching placebo. The primary outcome was a composite of progression of kidney disease (defined as end-stage kidney disease, a sustained decrease in eGFR to < 10 ml per minute per 1.73 m(2), a sustained decrease in eGFR of & GE;40% from baseline, or death from renal causes) or death from cardiovascular causes. Results A total of 6609 patients underwent randomization. During a median of 2.0 years of follow-up, progression of kidney disease or death from cardiovascular causes occurred in 432 of 3304 patients (13.1%) in the empagliflozin group and in 558 of 3305 patients (16.9%) in the placebo group (hazard ratio, 0.72; 95% confidence interval [CI], 0.64 to 0.82; P < 0.001). Results were consistent among patients with or without diabetes and across subgroups defined according to eGFR ranges. The rate of hospitalization from any cause was lower in the empagliflozin group than in the placebo group (hazard ratio, 0.86; 95% CI, 0.78 to 0.95; P=0.003), but there were no significant between-group differences with respect to the composite outcome of hospitalization for heart failure or death from cardiovascular causes (which occurred in 4.0% in the empagliflozin group and 4.6% in the placebo group) or death from any cause (in 4.5% and 5.1%, respectively). The rates of serious adverse events were similar in the two groups. Conclusions Among a wide range of patients with chronic kidney disease who were at risk for disease progression, empagliflozin therapy led to a lower risk of progression of kidney disease or death from cardiovascular causes than placebo