Representing dispositions

Dispositions and tendencies feature significantly in the biomedical domain and therefore in representations of knowledge of that domain. They are not only important for specific applications like an infectious disease ontology, but also as part of a general strategy for modelling knowledge about molecular interactions. But the task of representing dispositions in some formal ontological systems is fraught with several problems, which are partly due to the fact that Description Logics can only deal well with binary relations. The paper will discuss some of the results of the philosophical debate about dispositions, in order to see whether the formal relations needed to represent dispositions can be broken down to binary relations. Finally, we will discuss problems arising from the possibility of the absence of realizations, of multi-track or multi-trigger dispositions and offer suggestions on how to deal with them

A Late Pleistocene Wetland Setting in the Arid Jurf ed Darawish Region in Central Jordan

Current conditions in the southern Levant are hyperarid, and local communities rely on fossil subsurface water resources. The timing of more favourable wetter periods and also their spatial characteristics are not yet well constrained. To improve our understanding of past climate and environmental conditions in the deserts of the southern Levant, sedimentary sections including artefact-bearing beds from Jurf ed Darawish on the Central Jordanian Plateau were investigated using sedimentological and micropalaeontological analyses and OSL dating. Grain-size analysis and structures of the clayey-silty sediments show that they mainly represent reworked loess deposits. The OSL ages suggest that these fine-grained sediments were accumulated during Marine Isotope Stages (MIS) 5-3. Recorded ostracod valves (mostly Potamocypris, Ilyocypris and Pseudocandona), remains of aquatic and terrestrial gastropod shells, and charophyte gyrogonites and stem encrustations indicate that an in-stream wetland existed at the location of Jurf ed Darawish during MIS 5-4 which was replaced by a vegetated alluvial plain in MIS 3. The prevailing aggradational setting was replaced by an erosional setting sometime after 30 ka. Abundant artefacts, distributed over a vertical range of up to 40 cm in a bed covered by a sedimentary sequence of 12-m thickness, provide evidence for the presence of humans in the region during a relatively long period from ca. 85 to 65 ka. The reconstruction of an in-stream wetland at Jurf ed Darawish, and the presence of humans at the site and in other desert regions of the Jordanian Plateau, the Wadi Arava/Araba, and the Negev and the Nefud deserts, show that the regional climate in the late MIS 5 and MIS 4 was significantly wetter than today and provided favourable conditions for humans in the Southern Levant and the northwestern Arabian Peninsula

Host taxon-derived Sarcoptes mite in European wild animals revealed by microsatellite markers

Ten markers specific to Sarcoptes mites were used in applying microsatellite genotyping to individual Sarcoptes mites collected in three European countries from 15 wild mammal populations belonging to 10 host species. The results showed that geographical separation had real biological significance for the definition of mite sub-populations, and that the degree of genetic exchange occurring between mites from different localities was apparently related to the geographical distance between locations. Wild host-derived mite populations were found to be clustered into three main groups: herbivore-, carnivore- and omnivore-derived Sarcoptes populations, with the omnivore-derived group located halfway between the herbivore- and carnivore-derived Sarcoptes populations. The separation between these three mite groups was better supported than the geographical separations; nevertheless, a kind of sub-clustering was detected within each of these three groups that separates mite populations into their geographical localities (countries). The lack of gene flow between Sarcoptes populations may have improved parasitic adaptations and led to what we refer to as a host-taxon-derived (carnivore host-, herbivore host- and omnivore host-derived) Sarcoptes mite found on European wild animals. Our results demonstrate that Sarcoptes is not a single panmictic population, even within each geographical location. This finding will have important ramifications for the study of the genetic structure of populations, life cycles, diagnosis and the monitoring protocols of the ubiquitous Sarcoptes mite, and could thus contribute to a better understanding of its associated epidemiology, which is of pivotal interest for wildlife biological conservation. © 2010 Elsevier Ltd. All rights reserved.Peer Reviewe

Representing dispositions

Abstract Dispositions and tendencies feature significantly in the biomedical domain and therefore in representations of knowledge of that domain. They are not only important for specific applications like an infectious disease ontology, but also as part of a general strategy for modelling knowledge about molecular interactions. But the task of representing dispositions in some formal ontological systems is fraught with several problems, which are partly due to the fact that Description Logics can only deal well with binary relations. The paper will discuss some of the results of the philosophical debate about dispositions, in order to see whether the formal relations needed to represent dispositions can be broken down to binary relations. Finally, we will discuss problems arising from the possibility of the absence of realizations, of multi-track or multi-trigger dispositions and offer suggestions on how to deal with them.</p

The sequence of modules in the curriculum.

<p>It follows the stepwise layout of the GoodOD guideline and the increasing complexity of the contents. Modules 10–13 and 15–16 were used in the intervention (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0061425#pone-0061425-t001" target="_blank">Table 1</a>).</p

Intervention and data collection of the study.

<p>The intervention of the study consisted of the differential training of the students in certain content areas: students in group A received training in modules 10, 12 and 15 and no training in modules 11, 13 and 16, and <i>vice versa</i> for students in group B. Training sessions were kept balanced with regard to instructor, length, difficulty and instructional format. Data were collected in the form of ontology development exercises which were distributed evenly over all content areas with two exercises per training module.</p