SoK: Security Evaluation of SBox-Based Block Ciphers

Cryptanalysis of block ciphers is an active and important research area with an extensive volume of literature. For this work, we focus on SBox-based ciphers, as they are widely used and cover a large class of block ciphers. While there have been prior works that have consolidated attacks on block ciphers, they usually focus on describing and listing the attacks. Moreover, the methods for evaluating a cipher\u27s security are often ad hoc, differing from cipher to cipher, as attacks and evaluation techniques are developed along the way. As such, we aim to organise the attack literature, as well as the work on security evaluation. In this work, we present a systematization of cryptanalysis of SBox-based block ciphers focusing on three main areas: (1) Evaluation of block ciphers against standard cryptanalytic attacks; (2) Organisation and relationships between various attacks; (3) Comparison of the evaluation and attacks on existing ciphers

Adventures in Supersingularland

In this paper, we study isogeny graphs of supersingular elliptic curves. Supersingular isogeny graphs were introduced as a hard problem into cryptography by Charles, Goren, and Lauter for the construction of cryptographic hash functions [CGL06]. These are large expander graphs, and the hard problem is to find an efficient algorithm for routing, or path-finding, between two vertices of the graph. We consider four aspects of supersingular isogeny graphs, study each thoroughly and, where appropriate, discuss how they relate to one another. First, we consider two related graphs that help us understand the structure: the `spine' $\mathcal{S}$, which is the subgraph of $\mathcal{G}_\ell(\overline{\mathbb{F}_p})$ given by the $j$-invariants in $\mathbb{F}_p$, and the graph $\mathcal{G}_\ell(\mathbb{F}_p)$, in which both curves and isogenies must be defined over $\mathbb{F}_p$. We show how to pass from the latter to the former. The graph $\mathcal{S}$ is relevant for cryptanalysis because routing between vertices in $\mathbb{F}_p$ is easier than in the full isogeny graph. The $\mathbb{F}_p$-vertices are typically assumed to be randomly distributed in the graph, which is far from true. We provide an analysis of the distances of connected components of $\mathcal{S}$. Next, we study the involution on $\mathcal{G}_\ell(\overline{\mathbb{F}_p})$ that is given by the Frobenius of $\mathbb{F}_p$ and give heuristics on how often shortest paths between two conjugate $j$-invariants are preserved by this involution (mirror paths). We also study the related question of what proportion of conjugate $j$-invariants are $\ell$-isogenous for $\ell = 2,3$. We conclude with experimental data on the diameters of supersingular isogeny graphs when $\ell = 2$ and compare this with previous results on diameters of LPS graphs and random Ramanujan graphs.Comment: 46 pages. Comments welcom

On the dynamics of the adenylate energy system: homeorhesis vs homeostasis.

Biochemical energy is the fundamental element that maintains both the adequate turnover of the biomolecular structures and the functional metabolic viability of unicellular organisms. The levels of ATP, ADP and AMP reflect roughly the energetic status of the cell, and a precise ratio relating them was proposed by Atkinson as the adenylate energy charge (AEC). Under growth-phase conditions, cells maintain the AEC within narrow physiological values, despite extremely large fluctuations in the adenine nucleotides concentration. Intensive experimental studies have shown that these AEC values are preserved in a wide variety of organisms, both eukaryotes and prokaryotes. Here, to understand some of the functional elements involved in the cellular energy status, we present a computational model conformed by some key essential parts of the adenylate energy system. Specifically, we have considered (I) the main synthesis process of ATP from ADP, (II) the main catalyzed phosphotransfer reaction for interconversion of ATP, ADP and AMP, (III) the enzymatic hydrolysis of ATP yielding ADP, and (IV) the enzymatic hydrolysis of ATP providing AMP. This leads to a dynamic metabolic model (with the form of a delayed differential system) in which the enzymatic rate equations and all the physiological kinetic parameters have been explicitly considered and experimentally tested in vitro. Our central hypothesis is that cells are characterized by changing energy dynamics (homeorhesis). The results show that the AEC presents stable transitions between steady states and periodic oscillations and, in agreement with experimental data these oscillations range within the narrow AEC window. Furthermore, the model shows sustained oscillations in the Gibbs free energy and in the total nucleotide pool. The present study provides a step forward towards the understanding of the fundamental principles and quantitative laws governing the adenylate energy system, which is a fundamental element for unveiling the dynamics of cellular life

Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

Play for Change: Primary School for Children with Impairments

Within the architecture of education, there is a lack of attention to the needs of children with disability. Globally, one in every ten children have a disability and there are approximately 90,000 aged 0-14 children living in households who have at least one disability in New Zealand. The cohort is one of the most marginalised and excluded group from the society, resulting in an inability to participate in classes leading to fewer opportunities to develop skills, experience and confidence. School designs are designed for children without disability, and many children with disabilities find that classrooms and outdoor environments are ill-suited for their health needs, resulting in low attendance rates, poor peer engagement and limited educational success. This thesis explores the role of architecture in facilitating the education of children with disabilities. Working from research-led design through to design-led research, it examines architecture as an educational tool. Examining classroom spaces, outdoor play and outdoor learning environment for children with disabilities, it questions the purpose of education. In addition, the research aims to desensitise the perceived architectural barriers within primary school that restricts participation for children with disabilities. The architectural design knowledge aims to improve design approaches for inclusivity in school, pedagogy and outdoor play environments. By addressing this issue, it could potentially create more positive and optimistic views and from the wider community, greater disability awareness

Validation of the Test of Memory Malingering in a Dementia Population in Singapore

Bachelor'sBachelor of Social Sciences (Honours

Applying Frederick Herzberg's motivator-hygiene theory to tourism.

This paper attempts to employ Frederick Herzberg's motivator-hygiene theory to evaluate Singapore tourism environment

Designing Schools for Children with Impairments: The Powers of Architecture

© 2019 Common Ground Research Networks, Jacqueline McIntosh, Bruno Marques, Joelle Lim, All Rights Reserved. Education is an important foundation of society yet children with impairments have limited opportunities for participation in school activities. There is a lack of functionality in the design of school spaces and outdoor play areas for children with impairments, arguably as there are insufficient performance guidelines that target the body condition of children with impairments. Architectural barriers that prevent a child's participation in school can decrease their quality of life, often resulting in the further deterioration of their health. This research explores existing knowledge across disciplines aimed at promoting and facilitating impaired children's physical and mental resilience and well-being in a school environment. The research method involves systematic evaluation of the current school design knowledge surrounding the creation of learning environments that target children with impairments and proposes a set of performance-based design criteria. It finds that there is a lack of health research examining the usefulness of classroom and play spaces for children with impairments, which prohibit an ideal learning environment for children with multiple impairments. In addition, it finds a demand for greater integration of outdoor play with education, which in turn can make participation within schools more enjoyable

Normative Data on Serum and Plasma Tryptophan and Kynurenine Concentrations from 8089 Individuals Across 120 Studies: A Systematic Review and Meta-Analysis

In this systematic review and meta-analysis, a normative dataset is generated from the published literature on the kynurenine pathway in control participants extracted from case-control and methodological validation studies. Study characteristics were mapped, and studies were evaluated in terms of analytical rigour and methodological validation. Meta-analyses of variance between types of instruments, sample matrices and metabolites were conducted. Regression analyses were applied to determine the relationship between metabolite, sample matrix, biological sex, participant age and study age. The grand mean concentrations of tryptophan in the serum and plasma were 60.52 ± 15.38 μM and 51.45 ± 10.47 μM, respectively. The grand mean concentrations of kynurenine in the serum and plasma were 1.96 ± 0.51 μM and 1.82 ± 0.54 μM, respectively. Regional differences in metabolite concentrations were observed across America, Asia, Australia, Europe and the Middle East. Of the total variance within the data, mode of detection (MOD) accounted for up to 2.96%, sample matrix up to 3.23%, and their interaction explained up to 1.53%; the latter of which was determined to be negligible. This review was intended to inform future empirical research and method development studies and successfully synthesised pilot data. The pilot data reported in this study will inform future precision medicine initiatives aimed at targeting the kynurenine pathway by improving the availability and quality of normative data