The First Amendment and Content Restrictions in State Film Incentive Programs

In recent years, many states have offered incentive programs to lure film production and its associated economic benefits—increased jobs, spending, and tourism—to their states. Several of these programs have restrictions that deny incentives based on a film’s content. For example, Texas denies film incentives to projects that have “inappropriate content” or portray “Texas or Texans in a negative way.” This article concludes that these restrictions do not violate the First Amendment. Two key considerations factor into this conclusion: First, in granting subsidies, the government may apply criteria that would be impermissible in a regulatory context. Second, the denial of a subsidy is not the same as the infringement of a right

News Reporting on Trump\u27s COVID-19 Treatments: Should Broadcasters Have to Disclose their Being Potentially Dangerous?

During the early months of the COVID-19 pandemic in 2020, President Trump touted a number of treatments that many medical professionals considered dangerous. These treatments include hydroxychloroquine and disinfectants, which if misused could cause a patient’s death. This prompted Free Press to file an emergency petition with the FCC, arguing that broadcasters who report on Trump’s claims about these treatments without highlighting their dangers could be in violation of the Commission’s broadcast hoax rule. Free Press also requested the FCC require that broadcasters include disclaimers when reporting on such claims. This article examines whether the broadcast hoax rule has been violated here, and whether such disclaimers should be required. The preferred approach under the First Amendment is to leave it to the marketplace of ideas to ascertain the truth of Trump’s statements. This article ultimately concludes that the broadcast hoax rule is a poor fit for this case and that requiring disclaimers could chill broadcast coverage of the COVID-19 pandemic, leaving the public less informed about this important public health issue. Counterspeech, or providing accurate information to help counteract false statements, is the preferable approach here

Stepping Up: Burden Sharing by NATO\u27s Newest Members

This book examines the burden sharing behavior of new NATO members. It makes the argument that new NATO members are burden sharing at a greater rate than older NATO members. It also suggests that NATO’s expansion did not lead to greater free-riding behavior in NATO, contrary to the predictions of the collective action literature. This analysis reveals that new NATO members have demonstrated the willingness to contribute to NATO missions, but are often constrained by their limited capabilities. This argument is supported using case studies, interviews with key NATO officials, and quantitative analysis of NATO defense expenditures and troop contributions.https://press.armywarcollege.edu/monographs/1939/thumbnail.jp

The Relevance of the European Union and the North Atlantic Treaty Organization for the United States in the 21st Century

The “America First” approach to foreign policy seems to call into question the value of institutions like the North Atlantic Treaty Organization (NATO) and the European Union (EU). However, in a more competitive and uncertain strategic environment, NATO and the EU remain vital to promoting U.S. interests.https://press.armywarcollege.edu/monographs/1391/thumbnail.jp

Improved AIRS/AMSU Surface and Atmospheric Soundings Under Partial Cloud Cover Using an AIRS Only Cloud Clearing Approach

AIRS was launched on EOS Aqua on May 4,2002, together with AMSU-A and HSB, to form a next generation polar orbiting infrared and microwave atmospheric sounding system. This paper describes the latest scientific advances made in the AIRS Science Team Version 5.0 retrieval algorithm. Starting in early 2007, the Goddard DAAC will use this algorithm to analyze near real time AIRS/AMSU observations. These products are then made available to the scientific community for research purposes. The products include twice daily measurements of the Earth's three dimensional global temperature, water vapor, and ozone distribution as well as cloud cover. In addition, accurate twice daily measurements of the earth's land and ocean temperatures are derived and reported. Scientists use this important set of observations for two major uses. They provide important information for climate studies of global and regional variability and trends of different aspects of the earth's atmosphere. They also provide information for researchers to improve the skill of weather forecasting. A very important new product of the AIRS Version 5 algorithm is accurate case-by-case error estimates of the retrieved products. This heightens their utility for use in both weather and climate applications. These error estimates are also used directly for quality control of the retrieved products

The triad of Iron deficiency anemia, hepatosplenomegaly and growth retardation with normal serum zinc levels in a 14‑year‑old boy

A triad of iron deficiency anemia, hepatosplenomegaly and growth retardation occurring in tandem with zinc deficiency has been reported in the past as components of either Prasad’s syndrome or hypopituitarism. There are no documented cases of such triad occurring in the presence of normal serum zinc levels. We report a case of a 14‑year‑old boy who presented with iron deficiency anemia, hepatosplenomegaly, geophagia and growth retardation with pubertal delay. Investigations ruled out hypopituitarism and coeliac disease. The patient improved dramatically and attained puberty within 15 months of intense nutritional intervention. In conclusion, iron deficiency anemia occurring in the triad without zinc deficiency as seen in this case report has not been reported before; this calls for more research to be able to explain the findings.Key words: Growth retardation, hepatosplenomegaly, iron deficiency anemia, serum zin

THE INFLUENCE OF SPEED ON PATELLOFEMORAL JOINT KINETICS IN RECREATIONAL RUNNERS

This study aimed to determine the influence of running speed on patellofemoral joint (PFJ) kinetics. Twenty recreational runners ran on an instrumented treadmill at four running speeds with simultaneous 3D motion capture. A musculoskeletal model derived peak and cumulative (per 1km of continuous running) PFJ force and stress for each speed. Peak PFJ force and stress significantly increased with faster speeds. In contrast, cumulative PFJ measures decreased with faster speeds. Running at faster speeds increases the magnitude of peak PFJ kinetics but conversely results in less accumulated force over a set distance. Clinicians and coaches should be aware of the relatively high PFJ cumulative force and stress associated with slow running (~2.5 m/s) and consider moderate-speed interval running as part of overuse knee injury prevention and management plans

The Influence of Redcap in Improving the Quality of Data in Sickle Cell Medical Research Program: The Case of Sickle Cell Program at Muhimbili National Hospital

The study examined the influence of REDCap in improving the quality of data in sickle cell medical research program. The study used descriptive research design whereas both qualitative and quantitative approaches were used where a cross-sectional design was employed to collect information at one time in particular point. A total of 52 questionnaires with closed-ended questions were distributed. Primary data were collected through survey and in-depth interviews. Data were analyzed by using SPSS which simplified process of data analysis; the program identified the position of the variables and multiple regression analysis. The study found that there is effectiveness of REDCap in improving the quality of data in sickle cell medical research program in the sense that REDCap has effectively facilitated the collection of all necessary variables and essential information for research purposes. The study concluded that REDCap plays a significant role in improving the overall data quality in the context of sickle cell medical research programs. The study suggests that stringent quality control procedures should be implemented to ensure the accuracy and reliability of data input into the REDCap system. This recommendation underscores the importance of maintaining high standards in data management processes to enhance the credibility and validity of research outcomes in the field of sickle cell medical research.&nbsp

O-GIcNAc Transerase May Affect the Activity of Succinate Dehydrogenase

Undergraduate Basi

Reactive Chlorine Species Reversibly Inhibit DnaB Protein Splicing in Mycobacteria

Intervening proteins, or inteins, are mobile genetic elements that are translated within host polypeptides and removed at the protein level by splicing. In protein splicing, a self-mediated reaction removes the intein, leaving a peptide bond in place. While protein splicing can proceed in the absence of external cofactors, several examples of conditional protein splicing (CPS) have emerged. In CPS, the rate and accuracy of splicing are highly dependent on environmental conditions. Because the activity of the intein-containing host protein is compromised prior to splicing and inteins are highly abundant in the microbial world, CPS represents an emerging form of posttranslational regulation that is potentially widespread in microbes. Reactive chlorine species (RCS) are highly potent oxidants encountered by bacteria in a variety of natural environments, including within cells of the mammalian innate immune system. Here, we demonstrate that two naturally occurring RCS, namely, hypochlorous acid (the active compound in bleach) and N-chlorotaurine, can reversibly block splicing of DnaB inteins from Mycobacterium leprae and Mycobacterium smegmatis in vitro. Further, using a reporter that monitors DnaB intein activity within M. smegmatis, we show that DnaB protein splicing is inhibited by RCS in the native host. DnaB, an essential replicative helicase, is the most common intein-housing protein in bacteria. These results add to the growing list of environmental conditions that are relevant to the survival of the intein-containing host and influence protein splicing, as well as suggesting a novel mycobacterial response to RCS. We propose a model in which DnaB splicing, and therefore replication, is paused when these mycobacteria encounter RCS