Physical and chemical research microsheres obtained by plasma methods based on technogenic waste

In this paper, we present the results of research based on microspheres of ash waste of Ekibastuz GRES-1 obtained by the plasma method. Held XRF and IR spectral analyzes of the resulting microspheres. When comparing the infrared spectra of the feedstock, and the resulting microspheres based ASW plasma method, a shift of the fundamental absorption bands in the shortwave frequency range (absorption band at 1062.12 cm-1)

Videodisk TED Bildplatte

Methodology for preserving the audiovisual program repertoire heritage og the TED videodisk system, first industrial marketspace

Use of high-resolution mass spectrometry for veterinary drug multi-residue analysis

National and international food and feed safety authorities are shifting from routine-to risk-based monitoring. Risk-based monitoring requires flexibility in the scope of analytes, matrices, and sampling. Also, risk-based monitoring implies a desire for retrospective analysis using different scope(s) to follow trends, identify new food safety threats, and monitor the effectiveness of policy interventions. The current availability of sensitive and accurate high-resolution mass spectrometry (HRMS) fits within this approach. This writing reviews the applicability of HRMS techniques for food control laboratories in the analysis of veterinary medicinal products and hormones in food, using HRMS and legislative background. Different HRMS measurement and data evaluation strategies are identified and discussed. Among them, routine screening and confirmation, suspect screening, semi-untargeted analysis (common mass pattern search), metabolite and degradation product identification, profiling for deviating samples, physiological markers or treatments, and identification of unknowns can be found. The food safety competent authorities could shift from methods with predefined scope to real risk-based monitoring by implementing HRMS for routine food and feed analysis

Towards the Development of (Certified) Reference Materials for Effective Veterinary Drug Residue Testing in Food-producing Animals

Reliable analysis of veterinary drug residues in animal-derived foodstuffs represents an important measure to ensure consumer protection. European Legislation addresses this issue, for instance by defining maximum residue level, specifying sampling and monitoring plans, and stipulating performance and validation criteria for analytical methods. Certified reference materials (CRMs) constitute an important tool for method validation and method performance verification. This article addresses the current status of legislation, describes characteristics of analytical methods in veterinary drug residue testing and then focuses on the challenges and considerations towards the development of new (certified) reference materials in this fieldJRC.D.2-Reference material

Age related changes in cell stiffness of tendon stem/progenitor cells and a rejuvenating effect of ROCK-inhibition

Tendon stem/progenitor cells (TSPC) are potential targets for regenerative medicine and the treatment of tendon injuries. The frequency of such injuries increases in elderly patients while the proportion of functional TSPCs in tendon tissue decreases, protracting tendon repair. Using atomic force microscopy (AFM), we show that cell stiffness and size increase in TSPCs isolated from elderly patients (A-TSPC) compared to TSPCs from younger patients (Y-TSPC). Additionally, two-photon excited fluorescence (TPEF) microscopy revealed a denser, well-structured actin cytoskeleton in A-TSPC, which correlates with the augmented cell stiffness. Treating A-TSPC with ROCK-inhibitor, reverses these age-related changes, and has rejuvenating effect on cell morphology and stiffness. We assume that cellular stiffness is a suitable marker for cell aging and ROCK a potential target for therapeutic applications of cell rejuvenation. (C) 2019 The Authors. Published by Elsevier Inc