Effective Geothermal Utilisation close to the surface by the TT-Geothermal Radial Drilling (GRD-)Method

In the late 1970-Years, Tracto-Technik developped a very effective radial-shaped percussion system for a geothermal heating, the ECOtherm-System, which was very well accepted by customers. Nowadays, a radial-shaped drilling system, operating some decameters below the surface, was developped by Tracto-Technik, which offers the chance of a very effective drilling for the use of geothermal energy. The main advantage of this development is the reduction of drilling costs by new constructions and new handling possibilities. Drilling processes like the rod connecting or the drill-hole enlargement were solved in other ways as usual, by very time-shortening and effective ways, which are presented in the paper. The new TT-Geothermal radial drilling methods need only a very small but highly effective drilling unit, which reduces the operational drilling cost in a enormous way. All operational drilling steps are reduced to less than a half time as usual. By these GRD-methods, the use of surface-close geothermal energy is simplified and less expansive

Application-aware scheduling for VoIP in Wireless Mesh Networks

Wireless Mesh Networks (WMNs) are seen as a means to provide last mile connections in Next Generation Networks (NGNs). Because of their auto configuration capabilities and the low deployment cost WMNs are considered to be an efficient solution for the support of multiple voice, video and data services in NGNs. This paper looks at the optimal provision of resources in WMNs for Voice over IP (VoIP) traffic, which has strict performance requirements in terms of delay, jitter and packet loss. In WMNs, because of the challenges introduced by wireless multi hop transmissions and limited resources, providing performance quality for VoIP comparable to the voice quality in the traditional circuit switched networks is a major challenge. This paper analyses different scheduling mechanisms for TDMA based access control in mesh networks as specified in the IEEE 802.16 2004 WiMAX standard. The performance of the VoIP applications when different scheduling mechanisms are deployed is analysed on a variety of topologies using ns 2 simulation and mathematical analysis. The paper concludes that on demand scheduling of VoIP traffic typically deployed in 802.11 based WMNs is not able to provide the required VoIP quality in realistic mesh WiMAX network scenarios and is therefore not optimal from a network operator’s point of view. Instead, it is shown, that continuous scheduling is much better suited to serve VoIP traffic. The paper then proposes a new VoIP aware resource coordination scheme and shows, through simulation, that the new scheme is scalable and provides good quality for VoIP service in a wide range of network scenarios. The results shown in the paper prove that the new scheme is resilient to increasing hop count, increasing number of simultaneous VoIP sessions and the background traffic load in the network. Compared to other resource coordination schemes the VoIP aware scheduler significantly increases the number of supported calls

Enhanced spin-orbit coupling in core/shell nanowires

The spin-orbit coupling (SOC) in semiconductors is strongly influenced by structural asymmetries, as prominently observed in bulk crystal structures that lack inversion symmetry. Here, we study an additional effect on the SOC: the asymmetry induced by the large interface area between a nanowire core and its surrounding shell. Our experiments on purely wurtzite GaAs/AlGaAs core/shell nanowires demonstrate optical spin injection into a single free-standing nanowire and determine the effective electron g-factor of the hexagonal GaAs wurtzite phase. The spin relaxation is highly anisotropic in time-resolved micro-photoluminescence measurements on single nanowires, showing a significant increase of spin relaxation in external magnetic fields. This behavior is counterintuitive compared to bulk wurtzite crystals. We present a model for the observed electron spin dynamics highlighting the dominant role of the interface-induced SOC in these core/shell nanowires. This enhanced SOC may represent an interesting tuning parameter for the implementation of spin-orbitronic concepts in semiconductor-based structures

Identification and characterization of Iporin as a novel interaction partner for rab1

BACKGROUND: The small GTPase rab1a and its isoform rab1b are essential regulating components in the vesicle transport between the ER and the Golgi apparatus. Rab1 is thought to act as a molecular switch and can change between an active GTP-bound and an inactive GDP-bound conformation. To elucidate the function of rab1, several approaches have been established to isolate effector proteins, which interact with the activated conformation of rab1. To date p115, GM130, golgin-84 and MICAL have been identified as direct interacting partners. Together with rab1, these molecules are components of a protein complex, which mediates and regulates intracellular vesicle transport. RESULTS: Here, we report the characterization of Iporin, which is similar to KIAA0375 as a novel rab1-interacting protein. It was initially identified by yeast two-hybrid screening experiments with the active mutant of rab1b (rab1b Q67R) as bait. Iporin contains a SH3 domain and two polyproline stretches, which are known to play a role in protein/protein interactions. In addition, Iporin encloses a RUN domain, which seems to be a major part of the rab1binding domain (R1BD). Iporin is ubiquitously expressed and immunofluorescence staining displays a cytosolic punctual distribution. Interestingly, we also show that Iporin interacts with another rab1 interacting partner, the GM130 protein. CONCLUSION: Our results demonstrate that Iporin is a potential new interacting partner of rab1. Iporin is different from already identified rab1 interacting proteins concerning protein structure and cellular localization. We conclude that Iporin might function as a link between the targeting of ER derived vesicles, triggered by the rab1 GTPase and a signaling pathway regulated by molecules containing SH3 and/or poly-proline regions. The characterization of this novel intermolecular relation could help to elucidate how vesicles find their way from ER to the Golgi apparatus

The DNA binding parvulin Par17 is targeted to the mitochondrial matrix by a recently evolved prepeptide uniquely present in Hominidae

<p>Abstract</p> <p>Background</p> <p>The parvulin-type peptidyl prolyl <it>cis/trans </it>isomerase Par14 is highly conserved in all metazoans. The recently identified parvulin Par17 contains an additional N-terminal domain whose occurrence and function was the focus of the present study.</p> <p>Results</p> <p>Based on the observation that the human genome encodes Par17, but bovine and rodent genomes do not, Par17 exon sequences from 10 different primate species were cloned and sequenced. Par17 is encoded in the genomes of Hominidae species including humans, but is absent from other mammalian species. In contrast to Par14, endogenous Par17 was found in mitochondrial and membrane fractions of human cell lysates. Fluorescence of EGFP fusions of Par17, but not Par14, co-localized with mitochondrial staining. Par14 and Par17 associated with isolated human, rat and yeast mitochondria at low salt concentrations, but only the Par17 mitochondrial association was resistant to higher salt concentrations. Par17 was imported into mitochondria in a time and membrane potential-dependent manner, where it reached the mitochondrial matrix. Moreover, Par17 was shown to bind to double-stranded DNA under physiological salt conditions.</p> <p>Conclusion</p> <p>Taken together, the DNA binding parvulin Par17 is targeted to the mitochondrial matrix by the most recently evolved mitochondrial prepeptide known to date, thus adding a novel protein constituent to the mitochondrial proteome of Hominidae.</p

Транспортный комплекс в экономике России и его реформирование (на примере ООО ТЦП - Томский центр перевозок)

В данной работе была затронута тема о специфике работы транспортной логистики, проанализированы данные компании ООО "ТЦП", выявлены основные проблемы и проведена аналитика деятельности компанииIn this work, the topic of the specifics of the transport logistics analyzed the data of the company LLC TSP identified the main problems and carried out Analytics of the compan

Annoyance due to air pollution in Europe

Background Annoyance due to air pollution is a subjective score of air quality, which has been incorporated into the National Environmental monitoring of some countries. The objectives of this study are to describe the variations in annoyance due to air pollution in Europe and its individual and environmental determinants. Methods This study took place in the context of the European Community Respiratory Health Survey II (ECRHS II) that was conducted during 1999-2001. It included 25 centres in 12 countries and 7867 randomly selected adults from the general population. Annoyance due to air pollution was self-reported on an 11-point scale. Annual mean mass concentration of fine particles (PM2.5) and its sulphur (S) content were measured in 21 centres as a surrogate of urban air pollution. Results Forty-three per cent of participants reported moderate annoyance (1-5 on the scale) and 14% high annoyance (≥6) with large differences across centres (2-40% of high annoyance). Participants in the Northern European countries reported less annoyance. Female gender, nocturnal dyspnoea, phlegm and rhinitis, self-reported car and heavy vehicle traffic in front of the home, high education, non-smoking and exposure to environmental tobacco smoke were associated with higher annoyance levels. At the centre level, adjusted means of annoyance scores were moderately associated with sulphur urban levels (slope 1.43 μg m−3, standard error 0.40, r = 0.61). Conclusions Annoyance due to air pollution is frequent in Europe. Individuals' annoyance may be a useful measure of perceived ambient quality and could be considered a complementary tool for health surveillanc