Multiple View Geometry Transformers for 3D Human Pose Estimation

In this work, we aim to improve the 3D reasoning ability of Transformers in multi-view 3D human pose estimation. Recent works have focused on end-to-end learning-based transformer designs, which struggle to resolve geometric information accurately, particularly during occlusion. Instead, we propose a novel hybrid model, MVGFormer, which has a series of geometric and appearance modules organized in an iterative manner. The geometry modules are learning-free and handle all viewpoint-dependent 3D tasks geometrically which notably improves the model's generalization ability. The appearance modules are learnable and are dedicated to estimating 2D poses from image signals end-to-end which enables them to achieve accurate estimates even when occlusion occurs, leading to a model that is both accurate and generalizable to new cameras and geometries. We evaluate our approach for both in-domain and out-of-domain settings, where our model consistently outperforms state-of-the-art methods, and especially does so by a significant margin in the out-of-domain setting. We will release the code and models: https://github.com/XunshanMan/MVGFormer.Comment: 14 pages, 8 figure

Investigation on Combination of Airflow Disturbance and Sprinkler Irrigation for Horticultural Crop Frost Protection

Frost tends to be detrimental to the growth and development of horticultural crops, leading to yield or quality reduction with sizable economic losses. Therefore, it is very important to develop frost protection technology for horticultural crops. In this study, the development of frost protection technology is reviewed, and the research of mechanized frost protection technology in recent years is analyzed. In view of the poor frost protection effect of some single mechanized frost protection technology, the combination frost protection technology is put forward. The combination frost protection technology with airflow disturbance and sprinkler irrigation is discussed and analyzed

Reliability and External Validity of AMSTAR in Assessing Quality of TCM Systematic Reviews

Objective. The aim of this study is to measure the reliability and external validity of AMSTAR by applying it to a sample of TCM systematic reviews. Study Design and Methods. We tested the agreement, reliability, construct validity, and feasibility of AMSTAR through comparisons with OQAQ. Statistical analyses were performed by using SPSS 13.0. Results. A random of sample with 41 TCM systematic reviews was selected from a database. The interrater agreement of the individual items of AMSTAR was moderate with a mean kappa of 0.50 (95% CI: 0.26, 0.73). The ICC for AMSTAR against OQAQ (total score of 9 items, excluding item 10) was 0.87 (95% CI: 0.76, 0.93). Conclusions. Although there is room for improvement on few items, the new tool is reliable, valid, and easy to use for methodological quality assessment of systematic reviews on TCM

Meet-in-the-Middle Attacks Revisited: Key-recovery, Collision, and Preimage Attacks

At EUROCRYPT 2021, Bao et al. proposed an automatic method for systematically exploring the configuration space of meet-in-the-middle (MITM) preimage attacks. We further extend it into a constraint-based framework for finding exploitable MITM characteristics in the context of key-recovery and collision attacks by taking the subtle peculiarities of both scenarios into account. Moreover, to perform attacks based on MITM characteristics with nonlinear constrained neutral words, which have not been seen before, we present a procedure for deriving the solution spaces of neutral words without solving the corresponding nonlinear equations or increasing the overall time complexities of the attack. We apply our method to concrete symmetric-key primitives, including SKINNY, ForkSkinny, Romulus, Saturnin, Grostl, Whirlpool, and hashing modes with AES-256. As a result, we identify the first 23-round key-recovery attack on SKINNY-$n$-$3n$ and the first 24-round key-recovery attack on ForkSkinny-$n$-$3n$ in the single-key model. Moreover, improved (pseudo) preimage or collision attacks on round-reduced Whirlpool, Grostl, and hashing modes with AES-256 are obtained. In particular, employing the new representation of the AES key schedule due to Leurent and Pernot (EUROCRYPT 2021), we identify the first preimage attack on 10-round AES-256 hashing

Non-targeted Metabolomics Analysis of Metabolic Differences among Liuyang Douchi Fermented by Different Strains

In order to investigate the metabolic differences among Liuyang Douchi fermented by different starter cultures, the contents of total acid and amino nitrogen in Douchi fermented naturally and by using Aspergillus flavus 7214 (AF 7214), A. flavus 7622 (AF 7622), their mixture (AF 7214 + AF 7622) or A. orzyae were determined, and the difference in metabolites among these fermentation strategies was explored by liquid chromatography-mass spectrometry (LC-MS). The results showed that among the five Douchi samples, Douchi fermented by AF 7214 had the highest contents of total acid (3.52%) and amino nitrogen (1.47 g/100 g). The results of partial least squares discriminant analysis (PLS-DA) indicated that significant differences in metabolites were observed among the Douchi samples, and the composition of metabolites in Douchi fermented by AF 7622 showed the smallest difference from that in naturally fermented Douchi. Further analysis revealed that the differential metabolites between Douchi fermented naturally and by using starter cultures were mainly involved in amino acid metabolic pathways, especially arginine biosynthesis. A total of 62 key differential metabolites among the five samples were identified using variable importance in the projection (VIP) greater than 1.5 and P < 0.05 as criteria, including 26 amino acids and their derivatives such as L-lysine, L-serine and 2-methylserine, which indicated that enhanced fermentation showed the most notable influence on the metabolism of amino acids. This study has provided a new understanding of the formation of metabolites during the enhanced fermentation of Liuyang Douchi

Ancient introgression drives adaptation to cooler and drier mountain habitats in a cypress species complex

Funding: This work was supported by the National Natural Science Foundation of China (grant numbers 31590821, 31622015, 31370261), the National Basic Research Program of China (grant number 2014CB954100), Sichuan Provincial Department of Science and Technology (grant number 2015JQ0018) and Sichuan University (Fundamental Research Funds for the Central Universities, SCU2019D013, SCU 2018D006)Introgression may act as an important source of new genetic variation to facilitate the adaptation of organisms to new environments, yet how introgression might enable tree species to adapt to higher latitudes and elevations remains unclear. Applying whole-transcriptome sequencing and population genetic analyses, we present an example of ancient introgression from a cypress species (Cupressus gigantea) that occurs at higher latitude and elevation on the Qinghai-Tibet Plateau into a related species (C. duclouxiana), which has likely aided the latter species to extend its range by colonizing cooler and drier mountain habitats during postglacial periods. We show that 16 introgressed candidate adaptive loci could have played pivotal roles in response to diverse stresses experienced in a high-elevation environment. Our findings provide new insights into the evolutionary history of Qinghai-Tibet Plateau plants and the importance of introgression in the adaptation of species to climate change.Publisher PDFPeer reviewe

National incidence of traumatic fractures in China: a retrospective survey of 512 187 individuals

Background Traumatic fractures place a substantial burden on health-care systems worldwide. Although detailed information about incidence, distribution, and risk factors for traumatic fractures is vital for planning and prevention, in China, national data are unavailable. We aimed to do an up-to-date national survey on the population-weighted incidence of traumatic fractures in China. Methods The China National Fracture Study (CNFS) was a retrospective epidemiological study that recruited a nationally representative sample from eight provinces, 24 urban cities, and 24 rural counties in China using stratified random sampling and the probability proportional to size method. All eligible household members who had lived in their current residence for 6 months or longer were personally interviewed by trained research teams about traumatic fractures of the trunk, arms, or legs (not including the skull, sternum, and ribs) that had occurred in 2014. Telephone surveys were used for participants who were non-contactable after repeated visits. Fracture cases were verified by clinical records, medical history, and radiographs by orthopaedic surgeons and radiologists. We estimated incidence rates for traumatic fractures for the overall population and for subgroups by age and sex, as well as by demographic factors such as ethnic origin, occupation, geographical region, and residency category. We also studied potential associations between fractures and various factors of interest, such as age, ethnic origin, education, smoking, alcohol drinking, sleep time per day, and history of previous fracture. Data were weighted during statistical analysis to ascertain the national incidence rate. This study is registered with the Chinese Clinical Trial Registry, number ChiCTR-EPR-15005878. Findings Between Jan 19, 2015, and May 16, 2015, 535 836 individuals were selected and invited to participate in the study. Questionnaires from 23 649 (4%) individuals were excluded due to missing items, insufficient responses, or logical errors. Following exclusions, 512 187 (96%) individuals participated in the CNFS, consisting of 259 649 (51%) boys and men and 252 538 (49%) girls and women. Of these individuals, 1763 individuals had experienced traumatic fractures during 2014 (n=1833). The population-weighted incidence rate of traumatic fractures of the trunk, arms, or legs was 3·21 (95% CI 2·83–3·59) per 1000 population in 2014 (3·65, 3·12–4·18 in men and 2·75, 2·46–3·04 in women). For all ages, sleeping less than 7 h per day was identified as a risk factor for traumatic fractures. We identified previous fracture history as a risk factor for adults aged 15 years and older. Alcohol consumption incurred a risk effect for men aged 15 years and older and women aged 15–64 years. Interpretation Our results provide detailed information about fracture incidence, distribution, and risk factors, which can now be used as an up-to-date clinical evidence base for national health-care planning and preventive efforts in China and elsewhere. Specific public health policies that focus on decreasing alcohol consumption, prohibiting drunk driving, promoting smoking cessation, and encouraging individuals to obtain sufficient sleep and maintain a healthy bodyweight should be urgently implemented to help reduce the risk of traumatic fractures

The histone demethylase UTX regulates the lineage-specific epigenetic program of invariant natural killer T cells

Invariant natural killer T cells (iNKT cells) are innate-like lymphocytes that protect against infection, autoimmune disease and cancer. However, little is known about the epigenetic regulation of iNKT cell development. Here we found that the H3K27me3 histone demethylase UTX was an essential cell-intrinsic factor that controlled an iNKT-cell lineage-specific gene-expression program and epigenetic landscape in a demethylase-Activity-dependent manner. UTX-deficient iNKT cells exhibited impaired expression of iNKT cell signature genes due to a decrease in activation-Associated H3K4me3 marks and an increase in repressive H3K27me3 marks within the promoters occupied by UTX. We found that JunB regulated iNKT cell development and that the expression of genes that were targets of both JunB and the iNKT cell master transcription factor PLZF was UTX dependent. We identified iNKT cell super-enhancers and demonstrated that UTX-mediated regulation of super-enhancer accessibility was a key mechanism for commitment to the iNKT cell lineage. Our findings reveal how UTX regulates the development of iNKT cells through multiple epigenetic mechanisms