Fast and accurate simulations of transmission-line metamaterials using transmission-matrix method

Recently, two-dimensional (2D) periodically L and C loaded transmission-line (TL) networks have been applied to represent metamaterials. The commercial Agilent's Advanced Design System (ADS) is a commonly-used tool to simulate the TL metamaterials. However, it takes a lot of time to set up the TL network and perform numerical simulations using ADS, making the metamaterial analysis inefficient, especially for large-scale TL networks. In this paper, we propose transmission-matrix method (TMM) to simulate and analyze the TL-network metamaterials efficiently. Compared to the ADS commercial software, TMM provides nearly the same simulation results for the same networks. However, the model-process and simulation time has been greatly reduced. The proposed TMM can serve as an efficient tool to study the TL-network metamaterials.Comment: 15 pages, 13 figure

Age differences in search during self-regulated learning

While search is increasingly becoming a more central process in learning with the rise of electronic environments, little is known about how learners determine the points at which decide to move from one text to another. The current study aimed at examining how learners studying a domain in a multitext environment regulate their effort among multiple sources. Specifically, the goal was to understand the principles governing when learners discontinue reading about one topic to explore another in that domain. By manipulating the amount of new information and conceptual overlap across texts within a topic, we created three types of text environments to generate different trajectories of two cues to perceived learning, new information (measured by rating of perceived new information) and encoding fluency (measured by ratings of reading ease). We report a series of five studies (in Mechanical Turk and the lab; N=180), showing that learners leave one topic for another when perceived learning decreases. The dominant cue to gauge perceived learning was the perceived amount of new information, while encoding fluency became more important when the study time was limited or among the older adults with poorer verbal ability. Interestingly, older adults were able to take differential advantages of conceptual overlap across texts for learning the text in which was high in the amount of new information. The study extended theories in animal foraging and metacognition, and established a novel paradigm to better investigate adult learning in the wild

Using Wastewater-Based Epidemiology to Study Chlamydia Occurrence on a College Campus

Chlamydia is a sexually transmitted disease caused by Chlamydia trachomatis, commonly affecting sexually active college-aged adults. Presently, opportunistic testing, self-testing, and information campaigns are methods to screen vulnerable populations and raise awareness about chlamydia. Chlamydia remains underdiagnosed and undertested due to a lack of participation by individuals who may have been exposed to it. Wastewater-based epidemiology is a rising biomonitoring tool that detects the presence of disease- and drug-specific biomarkers in a community\u27s wastewater. In this study, wastewater-based epidemiology was used to detect the presence of C. trachomatis on the University of Central Florida campus. Wastewater samples were collected from two locations on campus from January 2022 to December 2022. The samples were pasteurized and filtered. DNA was extracted from the filters and was subsequently quantified using qPCR. C. trachomatis was detected at both sites of the UCF campus, with peaks corresponding to periods of the academic semester at which students arrived on campus or had fewer academic responsibilities. It was concluded that wastewater-based epidemiology provided a low-cost and non-invasive tool to notify the public of potential chlamydia outbreaks and encourage testing. Exploration in wastewater-based epidemiology should continue in research of C. trachomatis detection

Can Message-Tailoring Based on Regulatory Fit Theory Improve the Efficacy of Persuasive Physical Activity Systems?

© 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).Background: Many behaviour-change technologies have been designed to help people with a sedentary lifestyle to become more physically active. However, challenges exist in designing systems that work effectively. One of the key challenges is that many of those technologies do not account for differences in individuals’ psychological characteristics. To address that problem, tailoring the communication between a system and its users has been proposed and examined. Although in the research related to public health education, message tailoring has been studied extensively as a technique to communicate health information and to educate people, its use in the design of behaviour-change technologies has not been adequately investigated. Objective: The goal of this study was to explore the impact of message tailoring, when tailoring was grounded in Higgins’ Regulatory Fit Theory, and messages were constructed to promote physical activity. Method: An email intervention was designed and developed that sent participants daily health messages for 14 consecutive days. There were three categories of messages: reminders, promotion-, and prevention-messages. The effect of the messages on behaviour was compared between those who received messages that fitted their self-regulatory orientation, versus those who received non-fitted messages. Results: Participants who received promotion- or prevention-messages walked for longer periods of time, compared to those who received reminders in the control group. When comparing the first two groups, promotion-message-recipients on average walked more than those who received prevention-messages. In other words, promotion messages acted more persuasively than prevention-messages and reminders. Contrary to our hypothesis, those individuals who received messages that fitted their self-regulatory orientation did not walk more than those who received non-fitted messages. Conclusions: The efficacy of Higgins’ Regulatory Fit Theory in the design of tailored health messages was examined. This study did not find support for the use of that theory in guiding the design of persuasive health messages that promote physical activity. Therefore, more research is necessary to investigate the effectiveness of tailoring strategies.This research was funded by NSERC Discovery, grant number 132995

Memory and comprehension for health information among older adults: distinguishing the effects of domain-general and domain-specific knowledge

While there is evidence that knowledge influences understanding of health information, less is known about the processing mechanisms underlying this effect and its impact on memory. We used the moving window paradigm to examine how older adults varying in domain-general crystallised ability (verbal ability) and health knowledge allocate attention to understand health and domain-general texts. Participants (n = 107, age: 60-88 years) read and recalled single sentences about hypertension and about non-health topics. Mixed-effects modelling of word-by-word reading times suggested that domain-general crystallised ability increased conceptual integration regardless of text domain, while health knowledge selectively increased resource allocation to conceptual integration at clause boundaries in health texts. These patterns of attentional allocation were related to subsequent recall performance. Although older adults with lower levels of crystallised ability were less likely to engage in integrative processing, when they did, this strategy had a compensatory effect in improving recall. These findings suggest that semantic integration during reading is an important comprehension process that supports the construction of the memory representation and is engendered by knowledge. Implications of the findings for theories of text processing and memory as well as for designing patient education materials are discussed

Waveguide-plasmon polaritons enhance transverse magneto-optical Kerr effect

Magneto-optical effects in ferrimagnetic or ferromagnetic materials are usually too weak for potential applications. The transverse magneto-optical Kerr effect (TMOKE) in ferromagnetic films is typically on the order of 0.1%. Here, we demonstrate experimentally the enhancement of TMOKE due to the interaction of particle plasmons in gold nanowires with a photonic waveguide consisting of magneto- optical material, where hybrid waveguide-plasmon polaritons are excited. We achieve a large TMOKE that modulates the transmitted light intensity by 1.5%, accompanied by high transparency of the system. Our concept may lead to novel devices of miniaturized photonic circuits and switches, which are controllable by an external magnetic field

Exploring the role of teams and technology in patients' medication decision making

The final publication is available at Elsevier via https://doi.org/10.1016/j.japh.2018.12.010. © 2019. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/We know little about how electronic health records (EHRs) should be designed to help patients, pharmacists, and physicians participate in interprofessional shared decision making. We used a qualitative approach to understand better how patients make decisions with their health care team, how this information influences decision making about their medications, and finally, how this process can be improved through the use of EHRs.Canadian Institutes of Health Researc

Physician and Pharmacist Medication Decision-Making in the Time of Electronic Health Records: Mixed-Methods Study

©Kathryn Mercer, Catherine Burns, Lisa Guirguis, Jessie Chin, Maman Joyce Dogba, Lisa Dolovich, Line Guénette, Laurie Jenkins, France Légaré, Annette McKinnon, Josephine McMurray, Khrystine Waked, Kelly A Grindrod. Originally published in JMIR Human Factors (http://humanfactors.jmir.org), 25.09.2018. This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Human Factors, is properly cited. The complete bibliographic information, a link to the original publication on http://humanfactors.jmir.org, as well as this copyright and license information must be included.Background: Primary care needs to be patient-centered, integrated, and interprofessional to help patients with complex needs manage the burden of medication-related problems. Considering the growing problem of polypharmacy, increasing attention has been paid to how and when medication-related decisions should be coordinated across multidisciplinary care teams. Improved knowledge on how integrated electronic health records (EHRs) can support interprofessional shared decision-making for medication therapy management is necessary to continue improving patient care. Objective: The objective of our study was to examine how physicians and pharmacists understand and communicate patient-focused medication information with each other and how this knowledge can influence the design of EHRs. Methods: This study is part of a broader cross-Canada study between patients and health care providers around how medication-related decisions are made and communicated. We visited community pharmacies, team-based primary care clinics, and independent-practice family physician clinics throughout Ontario, Nova Scotia, Alberta, and Quebec. Research assistants conducted semistructured interviews with physicians and pharmacists. A modified version of the Multidisciplinary Framework Method was used to analyze the data. Results: We collected data from 19 pharmacies and 9 medical clinics and identified 6 main themes from 34 health care professionals. First, Interprofessional Shared Decision-Making was not occurring and clinicians made decisions based on their understanding of the patient. Physicians and pharmacists reported indirect Communication, incomplete Information specifically missing insight into indication and adherence, and misaligned Processes of Care that were further compounded by EHRs that are not designed to facilitate collaboration. Scope of Practice examined professional and workplace boundaries for pharmacists and physicians that were internally and externally imposed. Physicians decided on the degree of the Physician-Pharmacist Relationship, often predicated by colocation. Conclusions: We observed limited communication and collaboration between primary care providers and pharmacists when managing medications. Pharmacists were missing key information around reason for use, and physicians required accurate information around adherence. EHRs are a potential tool to help clinicians communicate information to resolve this issue. EHRs need to be designed to facilitate interprofessional medication management so that pharmacists and physicians can move beyond task-based work toward a collaborative approach

Host Gene Expression Profiling of Dengue Virus Infection in Cell Lines and Patients

Dengue is the most prevalent mosquito-born viral disease affecting humans, yet there is, at present, no drug treatment for the disease nor are there any validated host targets for therapeutic intervention. Using microarray technology to monitor the response of virtually every human gene, we aimed to identify the ways in which humans interact with dengue virus during infection in order to discover new therapeutic targets that could be exploited to control viral replication. From the activated genes, we identified three pathways common to in vitro and in vivo infection; the NF-κB initiated immune pathway, the type I interferon pathway, and the ubiquitin proteasome pathway. We next found that inhibiting the ubiquitin proteasome pathway, or activating the type I interferon pathway, resulted in significant inhibition of viral replication. However, inhibiting the NF-κB initiated immune pathway had no effect on viral replication. We suggest that drugs that target the ubiquitin proteasome pathway may prove effective at killing the dengue virus, and, if used therapeutically, improve clinical outcome in dengue disease