199 research outputs found

    NFL Players\u27 Perceptions of Female Athletic Trainers

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    Please enjoy Volume 7, Issue 1 of the JSMAHS. In this issue, you will find Professional, Graduate, and Undergraduate research abstracts, and case reports. Thank you for viewing this 7th Annual OATA Special Edition

    Struggling readers: Who they are, why they struggle, what helps them read, and the school librarian's role

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    A review of the literature indicates that very few researchers mention the school library or librarian when talking about how to help struggling readers. This research shows that in order to make the transition from struggling to successful readers, students need interesting and culturally relevant texts, individual solutions, and adult support. The school librarian can aid struggling readers by developing the school library collection, collaborating with all teachers to tailor the instruction of these students, and creating library programs that foster literacy and an environment of support

    Predicting Older Drivers\u27 Difficulties Using the Roadwise Review

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    There has been a substantial growth in research attempting to predict accidents and performance in older drivers. The Roadwise Review and the substantively identical Driver Health Inventory have been reported to provide a valid and cost-effective means of assessing crash risk in older communitydwelling adults. We administered the DHI to a community-dwelling sample of older (45 - 85 years) drivers. We also asked them to report on the difficulties they experienced while driving and on the frequency and type of crashes and moving violations the experienced in the previous two years. Results indicated on several of the tests there are substantial floor or ceiling effects, as well as barriers to usability and acceptance. Low inter-test correlations are consistent with the notion that different capacities are being indexed with the DHI. However, generally there were only low correlations between DHI performance and self-reported difficulties in driving, accidents or moving violations. While the DHI and Roadwise Review may well be valuable in providing older drivers with information on skills related to driving performance, in its current form it does not appear to be a useful tool in licensure or the prediction of driver risk

    Glycine max and Glycine soja are capable of cold acclimation

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    Soybean has been considered a cold intolerant species; based largely upon seed germination and soil emergent evaluations. This study reports a distinct acquisition of cold tolerance, in seedlings, following short acclimation periods. Diversity in cold responses was assessed in eight cultivars of Glycine max and six accessions of G. soja. All varieties of soybean significantly increased in freezing tolerance following acclimation. This study indicates soybean seedlings are indeed capable of sensing cold and acquiring cold tolerance. Germination rates after cold imbibition were negatively correlated with maturity group, but positively correlated with cold acclimation potential in G. soja. Seed fatty acid composition was varied between the species, with Glycine soja accessions containing about 2-times more linolenic acid (18:3) than G. max. Furthermore, high levels of linoleic acid (18:2) in seeds were positively correlated with germination rates following cold imbibition in G. soja only. We suggest that domestication has not impacted the overall ability of soybean to cold acclimate at the seedling stage and that there is little variation within the domesticated species for ability to cold acclimate. Thus, this brief comparative study reduces the enthusiasm for the “wild” species as an additional source of genetic diversity for cold tolerance

    Molecular chaperone Hsp90 stabilizes Pih1/Nop17 to maintain R2TP complex activity that regulates snoRNA accumulation

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    Hsp90 is a highly conserved molecular chaperone that is involved in modulating a multitude of cellular processes. In this study, we identify a function for the chaperone in RNA processing and maintenance. This functionality of Hsp90 involves two recently identified interactors of the chaperone: Tah1 and Pih1/Nop17. Tah1 is a small protein containing tetratricopeptide repeats, whereas Pih1 is found to be an unstable protein. Tah1 and Pih1 bind to the essential helicases Rvb1 and Rvb2 to form the R2TP complex, which we demonstrate is required for the correct accumulation of box C/D small nucleolar ribonucleoproteins. Together with the Tah1 cofactor, Hsp90 functions to stabilize Pih1. As a consequence, the chaperone is shown to affect box C/D accumulation and maintenance, especially under stress conditions. Hsp90 and R2TP proteins are also involved in the proper accumulation of box H/ACA small nucleolar RNAs

    Risk of Recurrence of Resected Stage I Non-small Cell Lung Cancer in Elderly Patients as Compared with Younger Patients

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    Half of all patients with non-small cell lung cancer (NSCLC) are 70 years or older at the time of diagnosis. Surgery is an option for fit elderly patients with early stage disease, but rates of disease recurrence after surgical resection are not well described. We report the outcomes in elderly patients (70 years or older) with stage I NSCLC after surgical resection.We conducted a retrospective study of patients diagnosed with stage I NSCLC after surgical resection at Washington University School of Medicine-Alvin J. Siteman Cancer Center from 1990 to 2000. Demographic, pathologic, treatment, and follow-up data were collected. Recurrence rates and overall survival were calculated by the Kaplan-Meier method. Multivariate Cox proportional hazards models were used to detect associations between potential prognostic factors and survival and recurrence.Of the 715 patients with stage I NSCLC, 286 were 70 years or older at diagnosis. In this elderly cohort, the median age was 74 years (range, 70–89 years) and 140 of them were women (49%). Lobectomy was performed in 237 patients (83%) whereas 43 patients (15%) had a wedge or segmental resection, and six patients (2%) underwent pneumonectomy. Clinical and pathologic characteristics were not statistically different between the elderly and younger cohorts, with the exception that older patients were more likely to be white (90% versus 80%, p = 0.0003) and less likely to be smokers (88% versus 95%, p = 0.019) compared with the younger cohort. With a median follow-up of 4.6 years, the overall 5-year survival rate was 52% with a 5-year recurrence rate of 24%. In comparison, the patients younger than 70 years had a 5-year survival rate of 67% (p < 0.001) and a 5-year recurrence rate of 24%.Although overall survival was worse in elderly patients, estimated disease recurrence rates after resection were identical
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