258 research outputs found

    City-Assisted Evacuation Plan Participant Survey Report

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    The survey of participants in the City Assisted Evacuation Program (CAEP) indicated a variety of perceptions about their evacuation experience during and after Hurricane Gustav. While the CAEP was generally regarded by most participants as successful, there are some aspects that were identified as needing improvement. Some of these can be improved by the city; some improvements are under the purview of the state or the federal government. Some can be fixed expeditiously; some will require a long-term commitment

    City-Assisted Evacuation Plan Participant Survey Report

    Get PDF
    The survey of participants in the City Assisted Evacuation Program (CAEP) indicated a variety of perceptions about their evacuation experience during and after Hurricane Gustav. While the CAEP was generally regarded by most participants as successful, there are some aspects that were identified as needing improvement. Some of these can be improved by the city; some improvements are under the purview of the state or the federal government. Some can be fixed expeditiously; some will require a long-term commitment

    Achieving Successful Long-Term Recovery and Safety from a Catastrophe: The Federal Role

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    Our task, reflected in this report, was to assess the government’s role in achieving long-term, safe recovery of the Gulf coast communities from the catastrophic disaster of Hurricanes Katrina and Rita in the early fall of 2005. The focus is on its catastrophic nature and the ability of our society to deal with such. This report offers our analysis with a focus on the federal government, per the national policy interests of the Ford Foundation. A companion book from the research is under preparation; it will consider the same question with the state and local government focus added to the federal response

    Patients’ and partners’ views of care and treatment provided for metastatic castrate resistant prostate cancer in the UK

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    Objective Documentations of the experiences of patients with advanced prostate cancer and their partners are sparse. Views of care and treatment received for metastatic castrate resistant prostate cancer (mCRPC) are presented here. Methods Structured interviews conducted within 14 days of a systemic therapy for mCRPC starting and 3 months later explored: treatment decisions, information provision, perceived benefits and harms of treatment, and effects of these on patients’ and partners’ lives. Results Thirty-seven patients and 33 partners recruited from UK cancer centres participated. The majority of patients (46%) reported pain was their worst symptom and many wanted to discuss its management (baseline-50%; 3 months-33%). Patients and partners believed treatment would: delay progression (>75%), improve wellbeing (33%), alleviate pain (≈12%) and extend life (15% -patients, 36% -partners). At 3 months most men (42%) said fatigue was the worst treatment-related side effect (SE), 27% experienced unexpected SEs, and 54% needed help with SEs. Most patients received SE information (85% written; 75% verbally); many additionally searched the internet (33%-patients; 55%-partners). Only 54% of patients said nurse support was accessible. Conclusion Pain and other symptom management is not optimal. Increased specialist nurse provision and earlier palliative care links are needed. Dedicated clinics may be justified

    Recombinant anticoccidial vaccines - a cup half full?

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    Eimeria species parasites can cause the disease coccidiosis, most notably in chickens. The occurrence of coccidiosis is currently controlled through a combination of good husbandry, chemoprophylaxis and/or live parasite vaccination; however, scalable, cost-effective subunit or recombinant vaccines are required. Many antigens have been proposed for use in novel anticoccidial vaccines, supported by the capacity to reduce disease severity or parasite replication, increase body weight gain in the face of challenge or improve feed conversion under experimental conditions, but none has reached commercial development. Nonetheless, the protection against challenge induced by some antigens has been within the lower range described for the ionophores against susceptible isolates or current live vaccines prior to oocyst recycling. With such levels of efficacy it may be that combinations of anticoccidial antigens already described are sufficient for development as novel multi-valent vaccines, pending identification of optimal delivery systems. Selection of the best antigens to be included in such vaccines can be informed by knowledge defining the natural occurrence of specific antigenic diversity, with relevance to the risk of immediate vaccine breakthrough, and the rate at which parasite genomes can evolve new diversity. For Eimeria, such data are now becoming available for antigens such as apical membrane antigen 1 (AMA1) and immune mapped protein 1 (IMP1) and more are anticipated as high-capacity, high-throughput sequencing technologies become increasingly accessible
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