Coherent manipulation of three-qubit states in a molecular single-ion magnet

We study the quantum spin dynamics of nearly isotropic Gd3+ ions entrapped in polyoxometalate molecules and diluted in crystals of a diamagnetic Y3+ derivative. The full energy-level spectrum and the orientations of the magnetic anisotropy axes have been determined by means of continuous-wave electron paramagnetic resonance experiments, using X-band (9-10 GHz) cavities and on-chip superconducting waveguides and 1.5-GHz resonators. The results show that seven allowed transitions between the 2S+1 spin states can be separately addressed. Spin coherence T2 and spin-lattice relaxation T1 rates have been measured for each of these transitions in properly oriented single crystals. The results suggest that quantum spin coherence is limited by residual dipolar interactions with neighbor electronic spins. Coherent Rabi oscillations have been observed for all transitions. The Rabi frequencies increase with microwave power and agree quantitatively with predictions based on the spin Hamiltonian of the molecular spin. We argue that the spin states of each Gd3+ ion can be mapped onto the states of three addressable qubits (or, alternatively, of a d=8-level "qudit"), for which the seven allowed transitions form a universal set of operations. Within this scheme, one of the coherent oscillations observed experimentally provides an implementation of a controlled-controlled-NOT (or Toffoli) three-qubit gate

Structural and solution speciation studies on selected [Cu(NN)(OO)] complexes and an investigation of their biomimetic activity, ROS generation and their cytotoxicity in normoxic, hypoxic and anoxic environments in MCF-7 breast cancer-derived cells

Reactive oxygen species(ROS) generation with subsequent DNA damage is one of the principle mechanisms of action assigned to copper-based anticancer complexes. The efficacy of this type of chemotherapeutic may be reduced in the low oxygen environment of tumours. In this study the cytotoxicity of three complexes, [Cu(dips)(phen)] (1), [Cu(ph)(phen)]·2H2O (2) and [Cu(ph)(bpy)]·H2O (3) (disp: 3,5-diisopropylsalicylate, phen: 1,10- phenanthroline, ph: phthalate, bpy: 2,2′-bipyridyl) were assessed for anticancer activity in the breast-cancer derived MCF-7 line under normoxic, hypoxic and anoxic conditions. In an immortalised keratinocyte HaCaT cell line, the cytotoxicity of complexes 2 and 3 was significantly reduced under both normoxic and hypoxic conditions, whilst the cytotoxicity of complex 1 was increased under hypoxic conditions. The ability of the complexes to generate ROS in the MCF-7 cell line was evaluated as was their ability to act as superoxide dismutase(SOD) and catalase mimics using a yeast cell assay. ROS generation was significant for complexes 2 and 3, less so for complex 1 though all three complexes had SOD mimetic ability. Given the ternary nature of the complexes, solution speciation studies were undertaken but were only successful for complex 3, due to solubility issues with the other two complexes. The concentration distribution of various species, formed in aqueous solution, was evaluated as a function of pH and confirmed that complex 3 is the dominant species at physiological pH in the mM concentration range. However, as its concentration diminishes, it experiences a progressive dissociation, leading to the formation of binary complexes of bpy alongside unbound phthalate. © 2023 The Author

Precise limits from lepton flavour violating processes on the Littlest Higgs model with T-parity

We recalculate the leading one-loop contributions to mu > e gamma and mu -> eee in the Littlest Higgs model with T-parity, recovering previous results for the former. When all the Goldstone interactions are taken into account, the latter is also ultraviolet finite. The present experimental limits on these processes require a somewhat heavy effective scale ~2.5 TeV, or the flavour alignment of the Yukawa couplings of light and heavy leptons at the ~10% level, or the splitting of heavy lepton masses to a similar precision. Present limits on tau decays set no bounds on the corresponding parameters involving the tau leptonComment: 41 pages, 11 figures; v3: matches published version in JHE

Insights into Nuclear Clusters in 28^{28}Si via Resonant Radiative Capture Measurements

International audienceThe heavyion radiative capture reaction 12C(16O,$\gamma$)28Si has been studied at three energies on( ELab = 20.0 and 21.2 MeV) and off( ELab = 20.7 MeV) resonance at Triumf (Vancouver) using the stateoftheart Dragon 0° spectrometer and its very efficient associated BGO $\gamma$ array. Intermediate states around Ex = 11.5 MeV, carrying a large part of the resonant flux have been observed for the first time in this system. The nature of those doorway states is discussed in terms of recently calculated cluster bands in 28Si. The results are compared to a recent similar investigation of the 12C(12C,$\gamma$)24Mg reaction

User guide BGS Coastal Vulnerability Index version 1

Coastal vulnerability indexing is a GIS-based analysis tool for indicating multi-hazards and interdependencies within the coastal zone of Great Britain (GB). The mainland of Great Britain is surrounded by over 11 000 miles of coastline. It is a very diverse coastline both in terms of geology and geomorphology, ranging from the high chalk cliffs of Sussex to the flat expanses of The Wash and Morecambe Bay. The coast has been shaped by the continual forces of erosion from the wind, waves and tide and the characteristics and composition of the coastline dictate the degree of its vulnerability. The winter storms of 2013-14 starkly demonstrated the vulnerability of the GB coastline to erosion and overtopping but during media enquiries it became clear that a national picture of the sections of coastline susceptible to erosion didn’t exist. The Coastal Vulnerability Index (CVI) has been created to bring together a suite of data to fill this knowledge gap. With climate change forecasts of an increase in the frequency and intensity of winter storms, BGS has developed a coastal vulnerability index (CVI), drawing on existing BGS datasets and expertise, and we intend to work in collaboration with other organisations to help manage these changes in the future. The CVI will offer anyone with assets or an interest in the coastline around Great Britain access to easy-to use indexes linked to geohazard data. This will allow users to interpret potential interdependencies in terms of erosion, flooding, habitat and other vulnerabilities. Version 1 of the CVI represents the natural geological coastline (around the mainland of GB only) as if no coastal defences or made ground are present. Due to their complex geometry, the coastlines of N and W Scotland have not been included in version 1. This will be of particular value in areas where coastal defences are no longer maintained. Future versions of the CVI will include all coastal defences and made ground

Identification and mitigation of a vibrational telescope systematic with application to spitzer

We observed Proxima Centauri with the Spitzer Space Telescope Infrared Array Camera five times in 2016 and 2017 to search for transits of Proxima Centauri b. Following standard analysis procedures, we found three asymmetric, transit-like events that are now understood to be vibrational systematics. This systematic is correlated with the width of the point-response function (PRF), which we measure with rotated and nonrotated-Gaussian fits with respect to the detector array. We show that the systematic can be removed with a novel application of an adaptive elliptical-aperture photometry technique, and compare the performance of this technique with fixed and variable circular-aperture photometry, using both BiLinearly Interpolated Subpixel Sensitivity (BLISS) maps and nonbinned Pixel-Level Decorrelation (PLD). With BLISS maps, elliptical photometry results in a lower standard deviation of normalized residuals, and reduced or similar correlated noise when compared to circular apertures. PLD prefers variable, circular apertures, but generally results in more correlated noise than BLISS. This vibrational effect is likely present in other telescopes and Spitzer observations, where correction could improve results. Our elliptical apertures can be applied to any photometry observations, and may be even more effective when applied to more circular PRFs than Spitzer's.The authors acknowledge support from the following: CATA-Basal/Chile PB06 Conicyt and Fondecyt/Chile project #1161218 (J.S.J.). Spanish MINECO programs AYA2016-79245-C03-03-P, ESP2017-87676-C05-02-R (E.R.), ESP2016-80435-C2-2-R (E.P.) and through the “Centre of Excellence Severo Ochoa” award SEV-2017-0709 (P.J.A.,C.R.-L., E.R.). STFC Consolidated Grant ST/P000592/1 (G.A.E.). NASA Planetary Atmospheres Program grant NNX12AI69G and NASA Astrophysics Data Analysis Program grant NNX13AF38G (R.C., J.H., K.M., M.H.). Spanish Ministry of Science, Innovation and Universities and the Fondo Europeo de Desarrollo Regional (FEDER) through grant ESP2016-80435-C2-1-R and PGC2018-098153-B-C33 (I.R.)

Decay of a Jπ=36+J^{\pi}=36^+ Resonance in the 24Mg+24Mg^{24}Mg + ^{24}Mg Reaction

The narrow ($\Gamma$=170 keV) and high spin ($J^{\pi}=36^+$) resonance in the $^{24}$Mg + $^{24}$Mg reaction at E$_{CM}$= 45.7 MeV has been associated with a hyperdeformed molecular state in $^{48}$Cr. Such a description has important consequences for the resonance decay into the favored inelastic channels. Through fragment- $\gamma$ coincidence measurements performed ON and OFF resonance using the PRISMA-CLARA array, we have identified the $^{24}$Mg states selectively populated: the $2^+$ and $4^+$ members of the ground state band

Observation of exclusive DVCS in polarized electron beam asymmetry measurements

We report the first results of the beam spin asymmetry measured in the reaction e + p -> e + p + gamma at a beam energy of 4.25 GeV. A large asymmetry with a sin(phi) modulation is observed, as predicted for the interference term of Deeply Virtual Compton Scattering and the Bethe-Heitler process. The amplitude of this modulation is alpha = 0.202 +/- 0.028. In leading-order and leading-twist pQCD, the alpha is directly proportional to the imaginary part of the DVCS amplitude.Comment: 6 pages, 5 figure

A Bayesian analysis of pentaquark signals from CLAS data

We examine the results of two measurements by the CLAS collaboration, one of which claimed evidence for a $\Theta^{+}$ pentaquark, whilst the other found no such evidence. The unique feature of these two experiments was that they were performed with the same experimental setup. Using a Bayesian analysis we find that the results of the two experiments are in fact compatible with each other, but that the first measurement did not contain sufficient information to determine unambiguously the existence of a $\Theta^{+}$. Further, we suggest a means by which the existence of a new candidate particle can be tested in a rigorous manner.Comment: 5 pages, 3 figure