Can we detect quantum gravity with compact binary inspirals?

Treating general relativity as an effective field theory, we compute the leading-order quantum corrections to the orbits and gravitational-wave emission of astrophysical compact binaries. These corrections are independent of the (unknown) nature of quantum gravity at high energies, and generate a phase shift and amplitude increase in the observed gravitational-wave signal. Unfortunately (but unsurprisingly), these corrections are undetectably small, even in the most optimistic observational scenarios.Comment: 7 pages, 0 figures; version 2 has additional discussion of our approach and 5 additional reference

The reported use and effectiveness of Hypericum (St John’s wort) on affective symptoms in a depression self-help group

A recent meta-analysis suggested that Hypericum perforatum (St John’s wort) is an effective treatment for mild to moderate depression and may have a superior side-effect profile to some antidepressant drugs. The aim of this study was to assess the use of herbal remedies in treating depressive and anxiety symptoms, as reported by members of the UK self-help organization Depression Alliance using self-completed questionnaires. More than 50% of the 452 respondents reported using Hypericum, onequarter of whom also reported concurrent use of traditional antidepressants. Most of the sample reported sufficient symptoms for warranting a diagnosis of major depression, with the majority also describing symptoms suggestive of co-morbid psychiatric conditions. One-half of the Hypericum users experienced symptom improvement, which for most occurred within the first 4 weeks of use. Response was better for those with mild as compared to severe symptoms and poorer for those taking Hypericum alongside other antidepressants. The responders were generally older than non-responders. Adverse effects were reported by one-quarter of users and were mostly psychological in nature. This retrospective survey indicated that use of herbal remedies was common in this population. Although often helpful in relieving symptoms, particularly in those with mild depression, there is a risk of adverse events and drug interaction

Explicit representation and parametrised impacts of under ice shelf seas in the z∗ coordinate ocean model NEMO 3.6

Ice-shelf-ocean interactions are a major source of freshwater on the Antarctic continental shelf and have a strong impact on ocean properties, ocean circulation and sea ice. However, climate models based on the ocean-sea ice model NEMO (Nucleus for European Modelling of the Ocean) currently do not include these interactions in any detail. The capability of explicitly simulating the circulation beneath ice shelves is introduced in the non-linear free surface model NEMO. Its implementation into the NEMO framework and its assessment in an idealised and realistic circum-Antarctic configuration is described in this study. Compared with the current prescription of ice shelf melting (i.e. at the surface), inclusion of open sub-ice-shelf cavities leads to a decrease in sea ice thickness along the coast, a weakening of the ocean stratification on the shelf, a decrease in salinity of high-salinity shelf water on the Ross and Weddell sea shelves and an increase in the strength of the gyres that circulate within the over-deepened basins on the West Antarctic continental shelf. Mimicking the overturning circulation under the ice shelves by introducing a prescribed meltwater flux over the depth range of the ice shelf base, rather than at the surface, is also assessed. It yields similar improvements in the simulated ocean properties and circulation over the Antarctic continental shelf to those from the explicit ice shelf cavity representation. With the ice shelf cavities opened, the widely used "three equation" ice shelf melting formulation, which enables an interactive computation of melting, is tested. Comparison with observational estimates of ice shelf melting indicates realistic results for most ice shelves. However, melting rates for the Amery, Getz and George VI ice shelves are considerably overestimated

Aspects of Nucleon Chiral Perturbation Theory

I review recent progress made in the calculation of nucleon properties in the framework of heavy baryon CHPT. Topics include: Compton scattering, $\pi N$ scattering, the anatomy of a low-energy constant and the induced pseudoscalar form factor.Comment: plain TeX (macro included), 12pp, lecture delivered at the workshop on "Chiral Dynamics: Theory and Experiments", MIT, July 25-29, 199

On the structure of large N cancellations in baryon chiral perturbation theory

We show how to compute loop graphs in heavy baryon chiral perturbation theory including the full functional dependence on the ratio of the Delta--nucleon mass difference to the pion mass, while at the same time automatically incorporating the 1/N cancellations that follow from the large-N spin-flavor symmetry of baryons in QCD. The one-loop renormalization of the baryon axial vector current is studied to demonstrate the procedure. A new cancellation is identified in the one-loop contribution to the baryon axial vector current. We show that loop corrections to the axial vector currents are exceptionally sensitive to deviations of the ratios of baryon-pion axial couplings from SU(6) values

Fracture clinic redesign reduces the cost of outpatient orthopaedic trauma care

Objectives: “Virtual fracture clinics” have been reported as a safe and effective alternative to the traditional fracture clinic. Robust protocols are used to identify cases that do not require further review, with the remainder triaged to the most appropriate subspecialist at the optimum time for review. The objective of this study was to perform a “top-down” analysis of the cost effectiveness of this virtual fracture clinic pathway. Methods: National Health Service financial returns relating to our institution were examined for the time period 2009 to 2014 which spanned the service redesign. Results: The total staffing costs rose by 4% over the time period (from £1 744 933 to £1 811 301) compared with a national increase of 16%. The total outpatient department rate of attendance fell by 15% compared with a national fall of 5%. Had our local costs increased in line with the national average, an excess expenditure of £212 705 would have been required for staffing costs. Conclusions: The virtual fracture clinic system was associated with less overall use of staff resources in comparison to national cost data. Adoption of this system nationally may have the potential to achieve significant cost savings

One-loop vertex integrals in heavy-particle effective theories

We give a complete analytical computation of three-point one-loop integrals with one heavy propagator, up to the third tensor rank, for arbitrary values of external momenta and masses.Comment: 10 pages, Latex, to appear in J. Phys.

Bosonic Operator Methods for the Quark Model

Quark model matrix elements can be computed using bosonic operators and the holomorphic representation for the harmonic oscillator. The technique is illustrated for normal and exotic baryons for an arbitrary number of colors. The computations are much simpler than those using conventional quark model wavefunctions

TDIR: Time-Delay Interferometric Ranging for Space-Borne Gravitational-Wave Detectors

Space-borne interferometric gravitational-wave detectors, sensitive in the low-frequency (mHz) band, will fly in the next decade. In these detectors, the spacecraft-to-spacecraft light-travel times will necessarily be unequal and time-varying, and (because of aberration) will have different values on up- and down-links. In such unequal-armlength interferometers, laser phase noise will be canceled by taking linear combinations of the laser-phase observables measured between pairs of spacecraft, appropriately time-shifted by the light propagation times along the corresponding arms. This procedure, known as time-delay interferometry (TDI), requires an accurate knowledge of the light-time delays as functions of time. Here we propose a high-accuracy technique to estimate these time delays and study its use in the context of the Laser Interferometer Space Antenna (LISA) mission. We refer to this ranging technique, which relies on the TDI combinations themselves, as Time-Delay Interferometric Ranging (TDIR). For every TDI combination, we show that, by minimizing the rms power in that combination (averaged over integration times $\sim 10^4$ s) with respect to the time-delay parameters, we obtain estimates of the time delays accurate enough to cancel laser noise to a level well below the secondary noises. Thus TDIR allows the implementation of TDI without the use of dedicated inter-spacecraft ranging systems, with a potential simplification of the LISA design. In this paper we define the TDIR procedure formally, and we characterize its expected performance via simulations with the \textit{Synthetic LISA} software package.Comment: 5 pages, 2 figure