Log-normal distributions of suspended particles in the open ocean

A scanning electron microscope-electron microprobe technique was used to chemically distinguish and size particles as fine as 0.2/µm on GEOSECS suspended matter filters from the open ocean…

Diagnosis of focal liver lesions from ultrasound using deep learning

PURPOSE: The purpose of this study was to create an algorithm that simultaneously detects and characterizes (benign vs. malignant) focal liver lesion (FLL) using deep learning. MATERIALS AND METHODS: We trained our algorithm on a dataset proposed during a data challenge organized at the 2018 Journées Francophones de Radiologie. The dataset was composed of 367 two-dimensional ultrasound images from 367 individual livers, captured at various institutions. The algorithm was guided using an attention mechanism with annotations made by a radiologist. The algorithm was then tested on a new data set from 177 patients. RESULTS: The models reached mean ROC-AUC scores of 0.935 for FLL detection and 0.916 for FLL characterization over three shuffled three-fold cross-validations performed with the training data. On the new dataset of 177 patients, our models reached a weighted mean ROC-AUC scores of 0.891 for seven different tasks. CONCLUSION: This study that uses a supervised-attention mechanism focused on FLL detection and characterization from liver ultrasound images. This method could prove to be highly relevant for medical imaging once validated on a larger independent cohort

Joint EANM/SIOPE/RAPNO practice guidelines/SNMMI procedure standards for imaging of paediatric gliomas using PET with radiolabelled amino acids and [¹⁸F]FDG: version 1.0

Positron emission tomography (PET) has been widely used in paediatric oncology. 2-Deoxy-2-[18F]fluoro-D-glucose ([18F]FDG) is the most commonly used radiopharmaceutical for PET imaging. For oncological brain imaging, different amino acid PET radiopharmaceuticals have been introduced in the last years. The purpose of this document is to provide imaging specialists and clinicians guidelines for indication, acquisition, and interpretation of [18F]FDG and radiolabelled amino acid PET in paediatric patients affected by brain gliomas. There is no high level of evidence for all recommendations suggested in this paper. These recommendations represent instead the consensus opinion of experienced leaders in the field. Further studies are needed to reach evidence-based recommendations for the applications of [18F]FDG and radiolabelled amino acid PET in paediatric neuro-oncology. These recommendations are not intended to be a substitute for national and international legal or regulatory provisions and should be considered in the context of good practice in nuclear medicine. The present guidelines/standards were developed collaboratively by the EANM and SNMMI with the European Society for Paediatric Oncology (SIOPE) Brain Tumour Group and the Response Assessment in Paediatric Neuro-Oncology (RAPNO) working group. They summarize also the views of the Neuroimaging and Oncology and Theranostics Committees of the EANM and reflect recommendations for which the EANM and other societies cannot be held responsible

Non-planar four-mirror optical cavity for high intensity gamma ray flux production by pulsed laser beam Compton scattering off GeV-electrons

As part of the R&D toward the production of high flux of polarised Gamma-rays we have designed and built a non-planar four-mirror optical cavity with a high finesse and operated it at a particle accelerator. We report on the main challenges of such cavity, such as the design of a suitable laser based on fiber technology, the mechanical difficulties of having a high tunability and a high mechanical stability in an accelerator environment and the active stabilization of such cavity by implementing a double feedback loop in a FPGA

Production of gamma rays by pulsed laser beam Compton scattering off GeV-electrons using a non-planar four-mirror optical cavity

As part of the positron source R&D for future $e^+-e^-$ colliders and Compton based compact light sources, a high finesse non-planar four-mirror Fabry-Perot cavity has recently been installed at the ATF (KEK, Tsukuba, Japan). The first measurements of the gamma ray flux produced with a such cavity using a pulsed laser is presented here. We demonstrate the production of a flux of 2.7 $\pm$ 0.2 gamma rays per bunch crossing ($\sim3\times10^6$ gammas per second) during the commissioning

CC9 Livestock-Associated Staphylococcus aureus Emerges in Bloodstream Infections in French Patients Unconnected With Animal Farming

We report 4 bloodstream infections associated with CC9 agr type II Staphylococcus aureus in individuals without animal exposure. We demonstrate, by microarray analysis, the presence of egc cluster, fnbA, cap operon, lukS, set2, set12, splE, splD, sak, epiD, and can, genomic features associated with a high virulence potential in human

The ThomX project status

Work supported by the French Agence Nationale de la recherche as part of the program EQUIPEX under reference ANR-10-EQPX-51, the Ile de France region, CNRS-IN2P3 and Université Paris Sud XI - http://accelconf.web.cern.ch/AccelConf/IPAC2014/papers/wepro052.pdfA collaboration of seven research institutes and an industry has been set up for the ThomX project, a compact Compton Backscattering Source (CBS) based in Orsay - France. After a period of study and definition of the machine performance, a full description of all the systems has been provided. The infrastructure work has been started and the main systems are in the call for tender phase. In this paper we will illustrate the definitive machine parameters and components characteristics. We will also update the results of the different technical and experimental activities on optical resonators, RF power supplies and on the electron gun

Pulsed Green Laser Wire System for Effective Inverse Compton Scattering

TUCYB2Laser-Compton scattering has become an important technique for beam diagnostics of the latest accelerators. In order to develop technologies for low emittance beams, an Accelerator Test facility (ATF) was built at KEK. It consists of an electron linac, a damping ring in which beam emittance is reduced, and an extraction line. For emittance measurement we are developing a new type of beam profile monitor which works on the principle of inverse Compton scattering between electron and laser light. In order to achieve effective collision of photon and electron, a pulsed and very thin size laser is required. Laser wire is one technique of measuring a small beam size. With green lasers, which are converted to second harmonics from IR pulsed laser, minimumbeam waist is half of the beam waist obtained using infrared (IR) laser oscillator. Therefore, it is possible to obtain beam waist less than 5 &m using green laser pulse, which is required for effective photon-electron collision. First, pulsed IR seed laser is amplified with 1.5 meter long PCF based amplifier system. This pulsed IR laser is converted to second harmonics with a non-linear crystal. Pulsed green laser is injected inside four mirror optical cavity to obtain very small beam waist at interaction point (IP). Using a pulsed compact laser wire, we can measure 10 um electron beams in vertical directions. We report the development of the pulsed green laser and parameters of compact four mirror optical cavity for effective inverse Compton scattering