An Incongruent Amalgamation: John Stuart Mill\u27s Utilitarianism on Naturalism

John Stuart Mill\u27s utilitarian principle of the greatest happiness for the greatest number, often surfaces in cultural debates in the contemporary West over the extent and foundations of moral duties. Given the drift from its historical Judeo-Christian moorings, naturalism now provides much of the epistemic grounding in Western culture in relation to moral duties. The amalgamation of Mill’s utilitarianism and naturalism has resulted in a cultural and epistemic disconnect. Naturalism is hard-pressed to provide consistent epistemic support for Mill’s utilitarian principle. This essay provides a number of suggestions as to why Mill’s utilitarianism may be inconsistent on naturalism

Addressing Barriers to Effective RTI through School Counselor Consultation: A Social Justice Approach

Response to Intervention (RTI) is a culturally responsive framework developed to provide targeted, evidence-based instruction to all students in regular education settings. A goal of RTI is to reduce the disproportionate number of students of color referred for special education services. However, numerous barriers often prevent teachers from effectively engaging in the RTI process and serve to impede the delivery of instruction. School counselors can provide rational emotive-social behavior (RE-SB) consultation for teachers to address psychosocial barriers and promote social justice. This article outlines RTI, barriers to implementation, and how school counselors can advocate for all students through RE-SB consultation

A Consensual Inquiry of Teachers’ Responses to Classroom Situations: Implications for School Counselors

Although often overlooked by school leaders, teacher emotions are key factors that impact classroom climate and therefore educational outcomes and student success. We use a framework grounded in rational emotive behavior therapy and social cognitive theory to explore teachers’ perceived thoughts, emotions, and behaviors in response to common classroom situations. The consensual qualitative research methodology was used to analyze data collected from 21 elementary school teachers. Findings suggest that psychosocial barriers exist among teachers who undermine effective instruction and classroom climate. Implications for school counselor practice are discussed

Mathematical analysis of a model for the growth of the bovine corpus luteum

The corpus luteum (CL) is an ovarian tissue that grows in the wound space created by follicular rupture. It produces the progesterone needed in the uterus to maintain pregnancy. Rapid growth of the CL and progesterone transport to the uterus require angiogenesis, the creation of new blood vessels from pre-existing ones, a process which is regulated by proteins that include fibroblast growth factor 2 (FGF2).\ud \ud In this paper we develop a system of time-dependent ordinary differential equations to model CL growth. The dependent variables represent FGF2, endothelial cells (ECs), luteal cells, and stromal cells (like pericytes), by assuming that the CL volume is a continuum of the three cell types. We assume that if the CL volume exceeds that of the ovulated follicle, then growth is inhibited. This threshold volume partitions the system dynamics into two regimes, so that the model may be classified as a Filippov (piecewise smooth) system.\ud \ud We show that normal CL growth requires an appropriate balance between the growth rates of luteal and stromal cells. We investigate how angiogenesis influences CL growth by considering how the system dynamics depend on the dimensionless EC proliferation rate, p5. We find that weak (low p5) or strong (high p5) angiogenesis leads to ‘pathological’ CL growth, since the loss of CL constituents compromises progesterone production or delivery. However, for intermediate values of p5, normal CL growth is predicted. The implications of these results for cow fertility are also discussed. For example, inadequate angiogenesis has been linked to infertility in dairy cows

Surface Brightness of Starbursts at Low and High Redshifts

Observations in the rest frame ultraviolet from various space missions are used to define the nearby starburst regions having the highest surface brightness on scales of several hundred pc. The bright limit is found to be 6x10^-16 ergs/cm^2-s-A-arcsec^2 for rest frame wavelength of 1830 A. Surface brightness in the brightest pixel is measured for 18 galaxies in the Hubble Deep Field having z > 2.2. After correcting for cosmological dimming, we find that the high redshift starbursts have intrinsic ultraviolet surface brightness that is typically four times brighter than low redshift starbursts. It is not possible to conclude whether this difference is caused by decreased dust obscuration in the high redshift starburst regions or by intrinsically more intense star formation. Surface brightness enhancement of starburst regions may be the primary factor for explaining the observed increase with redshift of the ultraviolet luminosity arising from star formation.Comment: accepted for publication in AJ; 11 pages text, 3 tables, 3 figures (embedded

Black Holes with a Massive Dilaton

The modifications of dilaton black holes which result when the dilaton acquires a mass are investigated. We derive some general constraints on the number of horizons of the black hole and argue that if the product of the black hole charge $Q$ and the dilaton mass $m$ satisfies $Q m < O(1)$ then the black hole has only one horizon. We also argue that for $Q m > O(1)$ there may exist solutions with three horizons and we discuss the causal structure of such solutions. We also investigate the possible structures of extremal solutions and the related problem of two-dimensional dilaton gravity with a massive dilaton.Comment: 36 pages with 5 figures (as uuencoded compressed tar file) (revised version has one major change in bound on mass for extremal solution and minor typos fixed), harvma

Treatment utilization and outcomes in elderly patients with locally advanced esophageal carcinoma: A review of the National Cancer Database

For elderly patients with locally advanced esophageal cancer, therapeutic approaches and outcomes in a modern cohort are not well characterized. Patients ≥70 years old with clinical stage II and III esophageal cancer diagnosed between 1998 and 2012 were identified from the National Cancer Database and stratified based on treatment type. Variables associated with treatment utilization were evaluated using logistic regression and survival evaluated using Cox proportional hazards analysis. Propensity matching (1:1) was performed to help account for selection bias. A total of 21,593 patients were identified. Median and maximum ages were 77 and 90, respectively. Treatment included palliative therapy (24.3%), chemoradiation (37.1%), trimodality therapy (10.0%), esophagectomy alone (5.6%), or no therapy (12.9%). Age ≥80 (OR 0.73), female gender (OR 0.81), Charlson-Deyo comorbidity score ≥2 (OR 0.82), and high-volume centers (OR 0.83) were associated with a decreased likelihood of palliative therapy versus no treatment. Age ≥80 (OR 0.79) and Clinical Stage III (OR 0.33) were associated with a decreased likelihood, while adenocarcinoma histology (OR 1.33) and nonacademic cancer centers (OR 3.9), an increased likelihood of esophagectomy alone compared to definitive chemoradiation. Age ≥80 (OR 0.15), female gender (OR 0.80), and non-Caucasian race (OR 0.63) were associated with a decreased likelihood, while adenocarcinoma histology (OR 2.10) and high-volume centers (OR 2.34), an increased likelihood of trimodality therapy compared to definitive chemoradiation. Each treatment type demonstrated improved survival compared to no therapy: palliative treatment (HR 0.49) to trimodality therapy (HR 0.25) with significance between all groups. Any therapy, including palliative care, was associated with improved survival; however, subsets of elderly patients with locally advanced esophageal cancer are less likely to receive aggressive therapy. Care should be taken to not unnecessarily deprive these individuals of treatment that may improve survival

Stereotactic body radiation therapy for the treatment of early-stage minimally invasive adenocarcinoma or adenocarcnioma in situ (formerly bronchioloalveolar carcinoma): A patterns of failure analysis

INTRODUCTION: Ongoing prospective trials exploring stereotactic body radiation therapy (SBRT) for early stage non-small cell lung cancer (NSCLC) often exclude minimally invasive adenocarcinoma or adenocarcnioma in situ, formerly bronchioloalveolar carcinoma (BAC), due to concerns for accurate target delineation on CT. We performed a patterns of failure analysis to compare outcomes between BAC and other NSCLC subtypes. METHODS: One hundred twenty patients with early stage NSCLC were treated with SBRT from 2004–2009. Pathologic confirmation of NSCLC was obtained in 97 patients. Radiotherapy was delivered according to RTOG guidelines. The log-rank test was used to compare outcomes between BAC and other NSCLC. RESULTS: Median follow-up was 29 months. The median SBRT dose was 5400 cGy. Thirteen patients had radiographically diagnosed BAC and five patients had biopsy confirmed BAC, of which two had both. The three-year local control was 100% for biopsy-proven or radiographically diagnosed BAC (n = 18) and 86% for all other NSCLC subtypes (n = 102) (p = 0.13). Likewise, no significant difference was detected between BAC and other NSCLC for 3-year regional failure (12% vs. 20%, p = 0.45), progression-free survival (57.6% vs. 53.5%, p = 0.84) or overall survival (35% vs. 47%, p = 0.66). There was a trend towards lower three-year rates of freedom from distant failure in patients with any diagnosis of BAC compared to those without (26% vs. 38%, p = 0.053). CONCLUSIONS: Compared to other NSCLC subtypes, BAC appears to have similar patterns of failure and survival after treatment with SBRT, however there may be an increased risk of distant metastases with BAC. RTOG guideline-based target delineation provides encouraging local control rates for patients with BAC

Addressing Barriers to Effective RTI through School Counselor Consultation: A Social Justice Approach

Response to Intervention (RTI) is a culturally responsive framework developed to provide targeted, evidence-based instruction to all students in regular education settings. A goal of RTI is to reduce the disproportionate number of students of color referred for special education services. However, numerous barriers often prevent teachers from effectively engaging in the RTI process and serve to impede the delivery of instruction. School counselors can provide rational emotive-social behavior (RE-SB) consultation for teachers to address psychosocial barriers and promote social justice. This article outlines RTI, barriers to implementation, and how school counselors can advocate for all students through RE-SB consultation