After the negotiations: assessing the impact of free trade agreements in Southern Africa

After protracted and difficult negotiations, agreement was recently reached on the dimensions of a South African-EU free trade deal. Because of South Africa's prominence in the sub-region, implementation of this agreement will have an impact not only on South Africa, but on all the SADC economies. This paper traces how this impact may be felt over time, using a multi-region model constructed to focus on the determination of sectoral and geographic trade patterns. By separatelymodeling South Africa and the rest of southern Africa, the model can be used to evaluate how alternative SADC regional trade strategies can influence how the EU deal affects the region's economies; by distinguishing among major trading partners (EU, North America, East Asia), the simulations can help illuminate how the trade deal will likely affect current trade patterns The empirical results lead to a number of conclusions: (1) trade creation dominates trade diversion for the region under all FTA arrangements; (2) the rest of southern Africa benefits from an FTA between the EU and South Africa — the recently signed bilateral agreement is not a “beggar thy neighbor” policy; (3) the rest of southern Africa gains more from zero-tariff access to EU markets than from a partial (50 percent) reduction in global tariffs; and (4) the South African economy is not large enough to serve as a growth pole for the region. Access to EU markets provides substantially bigger gains for the rest of southern Africa than does access to South Africa.Trade policy Africa., Free trade., South Africa.,

First-principles study of symmetry lowering in relaxed BaTiO3/SrTiO3 superlattices

The crystal structure and local spontaneous polarization of (BaTiO3)m/(SrTiO3)n superlattices is calculated using a first-principles density functional theory method. The in-plane lattice constant is 1% larger than the SrTiO3 substrate to imitate the relaxed superlattice structure and the symmetry is lowered to monoclinic space group Cm which allows polarization to develop along the [110] and [001] directions. The polarization component in the [110] direction is found to develop only in the SrTiO3 layers and falls to zero in the BaTiO3 layers, whereas the polarization in the [001] direction is approximately uniform throughout the superlattice. These findings are consistent with recent experimental data and first-principles results for epitaxially strained BT and ST.Comment: 4 pages, 2 figure

SHAPA: An interactive software tool for protocol analysis applied to aircrew communications and workload

As modern transport environments become increasingly complex, issues such as crew communication, interaction with automation, and workload management have become crucial. Much research is being focused on holistic aspects of social and cognitive behavior, such as the strategies used to handle workload, the flow of information, the scheduling of tasks, the verbal and non-verbal interactions between crew members. Traditional laboratory performance measures no longer sufficiently meet the needs of researchers addressing these issues. However observational techniques are better equipped to capture the type of data needed and to build models of the requisite level of sophistication. Presented here is SHAPA, an interactive software tool for performing both verbal and non-verbal protocol analysis. It has been developed with the idea of affording the researchers the closest possible degree of engagement with protocol data. The researcher can configure SHAPA to encode protocols using any theoretical framework or encoding vocabulary that is desired. SHAPA allows protocol analysis to be performed at any level of analysis, and it supplies a wide variety of tools for data aggregation, manipulation. The output generated by SHAPA can be used alone or in combination with other performance variables to get a rich picture of the influences on sequences of verbal or nonverbal behavior

Identification of novel chondroitin proteoglycans in Caenorhabditis elegans: embryonic cell division depends on CPG-1 and CPG-2.

Vertebrates produce multiple chondroitin sulfate proteoglycans that play important roles in development and tissue mechanics. In the nematode Caenorhabditis elegans, the chondroitin chains lack sulfate but nevertheless play essential roles in embryonic development and vulval morphogenesis. However, assignment of these functions to specific proteoglycans has been limited by the lack of identified core proteins. We used a combination of biochemical purification, Western blotting, and mass spectrometry to identify nine C. elegans chondroitin proteoglycan core proteins, none of which have homologues in vertebrates or other invertebrates such as Drosophila melanogaster or Hydra vulgaris. CPG-1/CEJ-1 and CPG-2 are expressed during embryonic development and bind chitin, suggesting a structural role in the egg. RNA interference (RNAi) depletion of individual CPGs had no effect on embryonic viability, but simultaneous depletion of CPG-1/CEJ-1 and CPG-2 resulted in multinucleated single-cell embryos. This embryonic lethality phenocopies RNAi depletion of the SQV-5 chondroitin synthase, suggesting that chondroitin chains on these two proteoglycans are required for cytokinesis

Melissa officinalis Extract Inhibits Herpes Simplex Virus-I Glycoprotein B Interaction with Heparin Sulfate

Herpes simplex virus 1, HSV1, is the primary cause of herpes labialis in humans. Drugslikeacycloviranditsderivativesareavailablefortreatment,butwithincreased use and the number of immune compromised patients, the development of resistance to these drugsisincreasing. Extracts of the botanical, Melissa officinalis, have previously been reported to contain antiviral activity toward HSV1. Our initial studies confirmed earlier results that constituents of Melissa officinalis interacted directly with the virus and inhibited HSV1 binding to cells during the initiation of infection. Further studies demonstrated that a component in Melissa officinalis bound specifically to the viral glycoprotein B. Virion structure was shown to be stable at low concentrations of Melissa officinalis, however at a ten-fold higher concentration than that which inhibited binding, virion structure was completely disrupted suggesting a second, virucidal, mode of inhibition. Melissa officinalis was shown to inhibit other alpha herpes viruses as well as having intermediate inhibitory activity against other viruses from the adenoviridae, poxviridae, papovaviridae, and rhabdoviridae families

Tongue Movements in Feeding and Speech

The position of the tongue relative to the upper and lower jaws is regulated in part by the position of the hyoid bone, which, with the anterior and posterior suprahyoid muscles, controls the angulation and length of the floor of the mouth on which the tongue body \u27rides\u27. The instantaneous shape of the tongue is controlled by the \u27extrinsic muscles \u27 acting in concert with the \u27intrinsic \u27 muscles. Recent anatomical research in non-human mammals has shown that the intrinsic muscles can best be regarded as a \u27laminated segmental system \u27 with tightly packed layers of the \u27transverse\u27, \u27longitudinal\u27, and \u27vertical\u27 muscle fibers. Each segment receives separate innervation from branches of the hypoglosssal nerve. These new anatomical findings are contributing to the development of functional models of the tongue, many based on increasingly refined finite element modeling techniques. They also begin to explain the observed behavior of the jaw-hyoid-tongue complex, or the hyomandibular \u27kinetic chain\u27, in feeding and consecutive speech. Similarly, major efforts, involving many imaging techniques (cinefluorography, ultrasound, electro-palatography, NMRI, and others), have examined the spatial and temporal relationships of the tongue surface in sound production. The feeding literature shows localized tongue-surface change as the process progresses. The speech literature shows extensive change in tongue shape between classes of vowels and consonants. Although there is a fundamental dichotomy between the referential framework and the methodological approach to studies of the orofacial complex in feeding and speech, it is clear that many of the shapes adopted by the tongue in speaking are seen in feeding. It is suggested that the range of shapes used in feeding is the matrix for both behaviors

Exploring the Relationship between AVID Professional Development and Teacher Leadership

Classroom teachers receive various forms of professional development throughout their careers with the intent of improving their teaching practices and ultimately, student performance. However, professional development can also have an impact on teacher leadership activities outside of the classroom as well. The purpose of this study is to assess whether professional development received from the Advancement Via Individual Determination (AVID) program has an effect on AVID elective teachers’ level of teacher leadership within their schools. Teachers from middle schools and high schools implementing, or planning to implement, AVID were examined in order to answer the following research questions: 1) Is teacher leadership affected by the quantity of professional development received from AVID Summer Institutes? 2) Is there a relationship between teacher leadership and teaching experience, as defined by the number of years teaching? 3) Are certain demographic variables, such as gender and level of education, associated with teacher leadership

Demonstration of Active Combustion Control

The primary objective of this effort was to demonstrate active control of combustion instabilities in a direct-injection gas turbine combustor that accurately simulates engine operating conditions and reproduces an engine-type instability. This report documents the second phase of a two-phase effort. The first phase involved the analysis of an instability observed in a developmental aeroengine and the design of a single-nozzle test rig to replicate that phenomenon. This was successfully completed in 2001 and is documented in the Phase I report. This second phase was directed toward demonstration of active control strategies to mitigate this instability and thereby demonstrate the viability of active control for aircraft engine combustors. This involved development of high-speed actuator technology, testing and analysis of how the actuation system was integrated with the combustion system, control algorithm development, and demonstration testing in the single-nozzle test rig. A 30 percent reduction in the amplitude of the high-frequency (570 Hz) instability was achieved using actuation systems and control algorithms developed within this effort. Even larger reductions were shown with a low-frequency (270 Hz) instability. This represents a unique achievement in the development and practical demonstration of active combustion control systems for gas turbine applications