38 research outputs found
XO-5b: A Transiting Jupiter-sized Planet With A Four Day Period
The star XO-5 (GSC 02959-00729, V=12.1, G8V) hosts a Jupiter-sized,
Rp=1.15+/-0.12 Rjup, transiting extrasolar planet, XO-5b, with an orbital
period of P=4.187732+/-0.00002 days. The planet mass (Mp=1.15+/-0.08 Mjup) and
surface gravity (gp=22+/-5 m/s^2) are significantly larger than expected by
empirical Mp-P and Mp-P-[Fe/H] relationships. However, the deviation from the
Mp-P relationship for XO-5b is not large enough to suggest a distinct type of
planet as is suggested for GJ 436b, HAT-P-2b, and XO-3b. By coincidence XO-5
overlies the extreme H I plume that emanates from the interacting galaxy pair
NGC 2444/NGC 2445 (Arp 143).Comment: 10 pages, 9 Figures, Submitted to Ap
The XO Planetary Survey Project - Astrophysical False Positives
Searches for planetary transits find many astrophysical false positives as a
by-product. There are four main types analyzed in the literature: a
grazing-incidence eclipsing binary star, an eclipsing binary star with a small
radius companion star, a blend of one or more stars with an unrelated eclipsing
binary star, and a physical triple star system. We present a list of 69
astrophysical false positives that had been identified as candidates of
transiting planets of the on-going XO survey. This list may be useful in order
to avoid redundant observation and characterization of these particular
candidates independently identified by other wide-field searches for transiting
planets. The list may be useful for those modeling the yield of the XO survey
and surveys similar to it. Subsequent observations of some of the listed stars
may improve mass-radius relations, especially for low-mass stars. From the
candidates exhibiting eclipses, we report three new spectroscopic double-line
binaries and give mass function estimations for 15 single lined spectroscopic
binaries.Comment: 13 pages, 4 figures, accepted to ApJ
A Transiting Planet of a Sun-like Star
A planet transits an 11th magnitude, G1V star in the constellation Corona
Borealis. We designate the planet XO-1b, and the star, XO-1, also known as GSC
02041-01657. XO-1 lacks a trigonometric distance; we estimate it to be 200+-20
pc. Of the ten stars currently known to host extrasolar transiting planets, the
star XO-1 is the most similar to the Sun in its physical characteristics: its
radius is 1.0+-0.08 R_Sun, its mass is 1.0+-0.03 M_Sun, V sini < 3 km/s, and
its metallicity [Fe/H] is 0.015+-0.04. The orbital period of the planet XO-1b
is 3.941534+-0.000027 days, one of the longer ones known. The planetary mass is
0.90+-0.07 M_Jupiter, which is marginally larger than that of other transiting
planets with periods between 3 and 4 days. Both the planetary radius and the
inclination are functions of the spectroscopically determined stellar radius.
If the stellar radius is 1.0+-0.08 R_Sun, then the planetary radius is
1.30+-0.11 R_Jupiter and the inclination of the orbit is 87.7+-1.2 degrees. We
have demonstrated a productive international collaboration between professional
and amateur astronomers that was important to distinguishing this planet from
many other similar candidates.Comment: 31 pages, 9 figures, accepted for part 1 of Ap
XO-2b: Transiting Hot Jupiter in a Metal-rich Common Proper Motion Binary
We report on a V=11.2 early K dwarf, XO-2 (GSC 03413-00005), that hosts a
Rp=0.98+0.03/-0.01 Rjup, Mp=0.57+/-0.06 Mjup transiting extrasolar planet,
XO-2b, with an orbital period of 2.615857+/-0.000005 days. XO-2 has high
metallicity, [Fe/H]=0.45+/-0.02, high proper motion, mu_tot=157 mas/yr, and has
a common proper motion stellar companion with 31" separation. The two stars are
nearly identical twins, with very similar spectra and apparent magnitudes. Due
to the high metallicity, these early K dwarf stars have a mass and radius close
to solar, Ms=0.98+/-0.02 Msolar and Rs=0.97+0.02/-0.01 Rsolar. The high proper
motion of XO-2 results from an eccentric orbit (Galactic pericenter, Rper<4
kpc) well confined to the Galactic disk (Zmax~100 pc). In addition, the phase
space position of XO-2 is near the Hercules dynamical stream, which points to
an origin of XO-2 in the metal-rich, inner Thin Disk and subsequent dynamical
scattering into the solar neighborhood. We describe an efficient Markov Chain
Monte Carlo algorithm for calculating the Bayesian posterior probability of the
system parameters from a transit light curve.Comment: 14 pages, 10 Figures, Accepted in ApJ. Negligible changes to XO-2
system properties. Removed Chi^2 light curve analysis section, and simplified
MCMC light curve analysis discussio
XO-3b: A Massive Planet in an Eccentric Orbit Transiting an F5V Star
We report the discovery of a massive (Mpsini = 13.02 +/- 0.64 Mjup; total
mass 13.25 +/- 0.64 Mjup), large (1.95 +/- 0.16 Rjup) planet in a transiting,
eccentric orbit (e = 0.260 +/- 0.017) around a 10th magnitude F5V star in the
constellation Camelopardalis. We designate the planet XO-3b, and the star XO-3,
also known as GSC 03727-01064. The orbital period of XO-3b is 3.1915426 +/-
0.00014 days. XO-3 lacks a trigonometric distance; we estimate its distance to
be 260 +/- 23 pc. The radius of XO-3 is 2.13 +/- 0.21 Rsun, its mass is 1.41
+/- 0.08 Msun, its vsini = 18.54 +/- 0.17 km/s, and its metallicity is [Fe/H] =
-0.177 +/- 0.027. This system is unusual for a number of reasons. XO-3b is one
of the most massive planets discovered around any star for which the orbital
period is less than 10 days. The mass is near the deuterium burning limit of 13
Mjup, which is a proposed boundary between planets and brown dwarfs. Although
Burrows et al. (2001) propose that formation in a disk or formation in the
interstellar medium in a manner similar to stars is a more logical way to
differentiate planets and brown dwarfs, our current observations are not
adequate to address this distinction. XO-3b is also unusual in that its
eccentricity is large given its relatively short orbital period. Both the
planetary radius and the inclination are functions of the spectroscopically
determined stellar radius. Analysis of the transit light curve of XO-3b
suggests that the spectroscopically derived parameters may be over estimated.
Though relatively noisy, the light curves favor a smaller radius in order to
better match the steepness of the ingress and egress. The light curve fits
imply a planetary radius of 1.25 +/- 0.15 Rjup, which would correspond to a
mass of 12.03 +/- 0.46 Mjup.Comment: 26 pages, 10 figures. Accepted by ApJ. Current version has several
small corrections as a result of a bug in the fitting softwar
NICMOS Observations of the Transiting Hot Jupiter XO-1b
We refine the physical parameters of the transiting hot Jupiter planet XO-1b
and its stellar host XO-1 using HST NICMOS observations. XO-1b has a radius
Rp=1.21+/-0.03 RJup, and XO-1 has a radius Rs=0.94+/-0.02 RSun, where the
uncertainty in the mass of XO-1 dominates the uncertainty of Rp and Rs. There
are no significant differences in the XO-1 system properties between these
broad-band NIR observations and previous determinations based upon ground-based
optical observations. We measure two transit timings from these observations
with 9 s and 15 s precision. As a residual to a linear ephemeris model, there
is a 2.0 sigma timing difference between the two HST visits that are separated
by 3 transit events (11.8 days). These two transit timings and additional
timings from the literature are sufficient to rule out the presence of an Earth
mass planet orbiting in 2:1 mean motion resonance coplanar with XO-1b. We
identify and correct for poorly understood gain-like variations present in
NICMOS time series data. This correction reduces the effective noise in time
series photometry by a factor of two, for the case of XO-1.Comment: 13 pages, 8 figures, submitted to Ap
Integrating complex genomic datasets and tumour cell sensitivity profiles to address a 'simple' question: which patients should get this drug?
It is becoming increasingly apparent that cancer drug therapies can only reach their full potential through appropriate patient selection. Matching drugs and cancer patients has proven to be a complex challenge, due in large part to the substantial molecular heterogeneity inherent to human cancers. This is not only a major hurdle to the improvement of the use of current treatments but also for the development of novel therapies and the ability to steer them to the relevant clinical indications. In this commentary we discuss recent studies from Kuo et al., published this month in BMC Medicine, in which they used a panel of cancer cell lines as a model for capturing patient heterogeneity at the genomic and proteomic level in order to identify potential biomarkers for predicting the clinical activity of a novel candidate chemotherapeutic across a patient population. The findings highlight the ability of a 'systems approach' to develop a better understanding of the properties of novel candidate therapeutics and to guide clinical testing and application
BioGPS: an extensible and customizable portal for querying and organizing gene annotation resources
BioGPS is a community based customisable gene annotation portal bringing together gene annotation resources on to a single platform
Gene Set Enrichment in eQTL Data Identifies Novel Annotations and Pathway Regulators
Genome-wide gene expression profiling has been extensively used to generate biological hypotheses based on differential expression. Recently, many studies have used microarrays to measure gene expression levels across genetic mapping populations. These gene expression phenotypes have been used for genome-wide association analyses, an analysis referred to as expression QTL (eQTL) mapping. Here, eQTL analysis was performed in adipose tissue from 28 inbred strains of mice. We focused our analysis on âtrans-eQTL bandsâ, defined as instances in which the expression patterns of many genes were all associated to a common genetic locus. Genes comprising trans-eQTL bands were screened for enrichments in functional gene sets representing known biological pathways, and genes located at associated trans-eQTL band loci were considered candidate transcriptional modulators. We demonstrate that these patterns were enriched for previously characterized relationships between known upstream transcriptional regulators and their downstream target genes. Moreover, we used this strategy to identify both novel regulators and novel members of known pathways. Finally, based on a putative regulatory relationship identified in our analysis, we identified and validated a previously uncharacterized role for cyclin H in the regulation of oxidative phosphorylation. We believe that the specific molecular hypotheses generated in this study will reveal many additional pathway members and regulators, and that the analysis approaches described herein will be broadly applicable to other eQTL data sets