Les enjeux identitaires de l’humain dans le débat philosophique sur la robotique humanoïde et l’amélioration humaine

ArticleLes représentations identitaires de l’humain (identité humaine, distinction naturel/artificiel) font-elles encore sens dans le contexte du développement de la robotique humanoïde (par l’humanisation du robot) et de l’amélioration humaine (par la robotisation de l’humain)? Le problème est que des philosophes critiques, comme Lin et Allhoff qui ont fondé la revue NanoEthics, remettent en question ces représentations identitaires de l’humain, comme si le discours de l’évaluation éthique fondée sur ces représentations était caduc quant aux deux questions qu’ils posent dans Ethics of Human Enhancement: 25 Questions and Answers en 2009: « Does the notion of human dignity suffer with human enhancements? » et « Is the natural-artificial distinction morally significant in this debate? » Le but du présent article sera de montrer, à partir de différents textes publiés, qui constituent notre cadre d’analyse des arguments moraux, la portée et l’insuffisance des arguments critiques que Lin et Allhoff utilisent pour répondre à ces deux questions. Mais, en appliquant à ces auteurs ce cadre de référence, nous pourrons aussi montrer en quoi la question de l’identité humaine ou la distinction naturel/artificiel fait encore sens dans l’évaluation éthique.Do human identity representations (human identity, natural/artificial distinction) still make sense in the context of the development of humanoid robotics (humanizing the robot) and human enhancement (automation of the human)? The problem is that critical philosophers, like Lin and Allhoff who founded the journal NanoEthics, challenge these representations of human identity, as if the discussion of the ethical evaluation of these representations was exhausted with regards to the two issues that they raise in 2009 in Ethics of Human Enhancement: 25 Questions and Answers, i.e.: “Does the notion of human dignity suffer with human enhancements?” and “Is the natural-artificial distinction morally significant in this debate?” The purpose of this article is to show – in light of various texts that constitute our framework for analyzing moral arguments – the limits of the scope and insufficiency of the critical arguments that Lin and Allhoff use to answer these two questions. But in applying our framework to these authors, we will also show how the question of human identity or the natural/artificial distinction still makes sense in the ethical evaluation

Premium food for offspring? Black-backed Woodpecker (Picoides arcticus) diet during breeding season in eastern Canada

Knowledge on the diet of the Black-backed Woodpecker (Picoides arcticus Swainson, 1832) is fragmentary and relies on a limited number of studies. Gaps remain in our understanding of the plasticity of its diet, particularly in the eastern part of its range. The main objective of this study was to assess the diet of Black-backed Woodpeckers in burned and unburned habitats and among sexes and ages in Québec. We collected feces and fecal bags from unburned and burned habitats in the Central Laurentians ecoregion of the eastern boreal shield ecozone and assessed diets based on identified prey items. Buprestidae and Cerambycidae of the sub-family Lamiinae were the predominant prey for adult Black-backed Woodpeckers in burned habitats, and the Pythidae Pytho niger (Kirby, 1837) and Lamiinae were the most prevalent prey in unburned habitats. Lamiinae were the most predominant prey items provisioned to nestling in burned habitat, while P. niger was their predominant food in unburned habitat, followed by Cerambycidae (without Lamiinae) and Lamiinae. Our results present new insights into Black-backed Woodpecker diet where parents feed their offspring with the largest prey available, potentially providing higher fitness for their offspring. Furthermore, our study confirms that Black-backed Woodpeckers, at least in the eastern part of its range, are not restricted to feed on Lamiinae but are rather opportunistic in taking advantage from resource–pulse interactions provided by recently disturbed habitats, especially from recently burned habitats

Impact of ultraviolet radiation on marine crustacean zooplankton and ichthyoplankton: a synthesis of results from the estuary and Gulf of St. Lawrence, Canada

The objectives of the research program reported upon here were (1) to measure ambient levels of UV radiation and determine whichvariables most strongly affected its attenuation in the waters of the estuary and Gulf of St. Lawrence, Canada; and (2) to investigate the potential direct impacts of W radiation on species of crustacean zooplankton and fish whose early life stages are planktonic. In this geographic region, productivity-determining biophysical interactions occur in the upper 0 to 30 m of the water column. Measurements of the diffuse attenuation coefficients for ultraviolet-B radiation (W-B, 280 to 320 nm) at various locations in this region indicated maximum 10% depths (the depth to which 10% of the surface energy penetrates at a given wavelength) of 3 to 4 m at a wavelength of 310 nm. Organisms residing in this layer-including the eggs and larvae of Calanus finmarchicus and Atlantic cod Gadus morhua-are exposed to biologically damaging levels of W radiation. As a result of these physical and biological characteristics, this system offered a relevant opportunity to assess the impacts of UV on subarctic marine ecosystems. Eggs of C. finmarchicus were incubated under the sun, with and without the W-B and/or UV-A (320 to 400 nm) wavebands. W-exposed eggs exhibited low percent hatchmg compared to those protected from W : W radiation had a strong negative impact on C. finmarchicus eggs. Further, percent hatching in W-B-exposed eggs was not significantly lower than that in eggs exposed to UV-A only: under natural sunlight, UV-A radiation appeared to be more detrimental to C. finmarchicus embryos than was UV-B. In analogous experiments with Atlantic cod eggs, exposure to UV-B produced a significant negative effect. However, UV-A had no negative effect on cod eggs. Additional experiments using a solar simulator (SS) revealed high wavelength-dependent mortality in both C. finmarchicus and cod embryos exposed to UV. The strongest effects occurred under exposures to wavelengths below 312 nm. At the shorter wavelengths (<305 nm) UV-B-induced mortality was strongly dose-dependent, but (for both C. finmarchicus and cod) not significantly influenced by dose-rate. Thus, at least within the limits of the exposures under which the biological weighting functions (BWFs) were generated, reciprocity held. The BWFs derived for UV-B-induced mortality in C. finmarchicus and cod eggs were similar in shape to the action spectrum for UV-B effects on naked DNA. Further, the wavelengthdependence of DNA damage was similar to that for the mortality effect. These observations suggest that W-induced mortality in C. finmarchicus and cod eggs is a direct result of DNA damage. There was no evidence of a detrimental effect of UV-A radiation in these SS-derived results. A mathematical model that includes the BWFs, vertical mixing of eggs, meteorological and hydrographic conditions, and ozone depletion, indicates that W-induced mortality in the C. finmarchicus egg population could be as high as 32.5 %, while the impact on the cod egg population was no more than 1.2%. Variability in cloud cover, water transparency (and the variables that affect it), and vertical distribution and displacement of planktonic organisms within the mixed layer can all have a greater effect on the flux of UV-B radiation to which they are exposed than will ozone layer depletion at these latitudes. Our observations indicate that C, finmarchicus and cod eggs present in the first meter of the water column (likely only a small percentage of the total egg populations) are susceptible to W radiation. However, although exposure to UV can negatively impact crustacean zooplankton and ichthyoplankton populations, these direct effects are likely minimal within the context of all the other environmental factors that produce the very high levels of mortality typically observed in their planktonic early life stages. The impact of indnect effects-which may well be of much greater import-has yet to be evaluated

The 20S proteasome core, active within apoptotic exosome-like vesicles, induces autoantibody production and accelerates rejection

Autoantibodies to components of apoptotic cells, such as anti-perlecan antibodies, contribute to rejection in organ transplant recipients. However, mechanisms of immunization to apoptotic components remain largely uncharacterized. We used large-scale proteomics, with validation by electron microscopy and biochemical methods, to compare the protein profiles of apoptotic bodies and apoptotic exosome-like vesicles, smaller extracellular vesicles released by endothelial cells downstream of caspase-3 activation. We identified apoptotic exosome-like vesicles as a central trigger for production of anti-perlecan antibodies and acceleration of rejection. Unlike apoptotic bodies, apoptotic exosome-like vesicles triggered the production of anti-perlecan antibodies in naïve mice and enhanced anti-perlecan antibody production and allograft inflammation in mice transplanted with an MHC (major histocompatibility complex)–incompatible aortic graft. The 20S proteasome core was active within apoptotic exosome-like vesicles and controlled their immunogenic activity. Finally, we showed that proteasome activity in circulating exosome-like vesicles increased after vascular injury in mice. These findings open new avenues for predicting and controlling maladaptive humoral responses to apoptotic cell components that enhance the risk of rejection after transplantation

The Social and Ethical Acceptability of NBICs for Purposes of Human Enhancement: Why Does the Debate Remain Mired in Impasse?

The emergence and development of convergent technologies for the purpose of improving human performance, including nanotechnology, biotechnology, information sciences, and cognitive science (NBICs), open up new horizons in the debates and moral arguments that must be engaged by philosophers who hope to take seriously the question of the ethical and social acceptability of these technologies. This article advances an analysis of the factors that contribute to confusion and discord on the topic, in order to help in understanding why arguments that form a part of the debate between transhumanism and humanism result in a philosophical and ethical impasse: 1. The lack of clarity that emerges from the fact that any given argument deployed (arguments based on nature and human nature, dignity, the good life) can serve as the basis for both the positive and the negative evaluation of NBICs. 2. The impossibility of providing these arguments with foundations that will enable others to deem them acceptable. 3. The difficulty of applying these same arguments to a specific situation. 4. The ineffectiveness of moral argument in a democratic society. The present effort at communication about the difficulties of the argumentation process is intended as a necessary first step towards developing an interdisciplinary response to those difficulties

L’intelligence artificielle : un levier permettant de restaurer l’égalité?

The international conference “Pour des intelligences artificielles au service du corps vulnérable&nbsp;: Les contreforts de l’éthique et du droit” held in December 2021 at the Université catholique de Lyon, in France, explored whether artificial intelligence (AI) be a lever to restore equality between poor and rich, women and men, the disabled, the elderly? In the context of the Covid-19 pandemic, this question is being asked everywhere, including various international bodies, such as the United Nations (UN) and the International Communications Union (ICU). This question requires an impact analysis (leverage) of AI that can generate more social justice (reduction of inequalities). How can we produce such an analysis so that AI can benefit everyone without excluding citizens from marginalized communities? The difficult ethical problem to solve is the following: how far does the impact of AI maximize justice by reducing inequalities? Here the analysis relies on knowledge of AI features that can have a real or negative impact. The purpose of this paper will be to show, based on our framework for analyzing technology impacts and various published texts, the strengths and weaknesses of AI, to answer this question. Applying this framework, we proceed as follows: 1) situate the complex problem of inequalities: those that are generational and socio-economic in nature to which AI has little impact; inequalities to which AI can have an impact, including digital inclusion and social inequalities; 2) situate the terminology of AI: weak (algorithms) or complete (decisional and autonomous) AI; 3) do an analysis of inequalities: digital inclusion and social inequalities showing the strengths and weaknesses of AI.Le Journée d’étude «&nbsp;Pour des intelligences artificielles au service du corps vulnérable&nbsp;: Les contreforts de l’éthique et du droit » tenu en décembre 2021 à l’Université catholique de Lyon, en France, a permis d’explorer si l’intelligence artificielle (IA) pouvait être un levier permettant de restaurer l’égalité entre les pauvres et les riches, les femmes et les hommes, les handicapés, les sujets âgés? En contexte de pandémie Covid-19, cette question se pose partout, incluant diverses instances internationales, comme les Nations Unies (ONU) et l’Union internationale des communications (UTI). Cette question nécessite de faire une analyse d’impact (levier) de l’IA pouvant engendrer plus de justice sociale (réduction des inégalités). Comment produire une telle analyse pour que l’IA puisse bénéficier à toutes et à tous sans exclure des citoyennes et citoyens de communautés marginalisées? Le problème éthique difficile à résoudre est le suivant : jusqu’où l’impact de l’IA maximise-t-il la justice en réduisant les inégalités? Ici l’analyse repose sur la connaissance des dispositifs de l’IA pouvant avoir un impact réel ou négatif. Le but de cette présentation sera de montrer, à partir de notre cadre d’analyse d’impacts des technologies et de différents textes publiés, les forces et faiblesses de l’IA, pour répondre à cette question. En appliquant ce cadre de référence, nous procédons de la façon suivante : 1) situer le problème complexe des inégalités: celles qui sont de nature générationnelle et socioéconomique auxquelles l’IA n’a que peu d’impacts; des inégalités auxquelles l’IA peut avoir des impacts, dont l’inclusion numérique et les inégalités sociales; 2) situer la terminologie de l’IA : IA faible (algorithmes) ou complète (décisionnelle et autonome); 3) faire une analyse des inégalités : inclusion numérique et inégalités sociales montrant les forces et faiblesses de l’IA

Introduire le changement dans les systèmes de soins au Québec : comment tirer profit de l'expérimentation sociale ?

Introducing change in health care Systems from Quebec: how to benefit from social experimentation? Based on an implementation analysis of an experimentation of a System of integrated care for frail elderly (in the province of Quebec, Canada), this paper initiates reflections about the introduction of reforms in health care Systems. It highlights the advantages of decentralized, participatory change stratégies, based on social experimentation. Theses strategies are particularly interesting in the case of complex changes, in which they in fact allow the autonomy necessary for learning. In conclusion, we propose some hypotheses concerning factors which make these social experimentations successful.Résumé. En s'appuyant sur l'évaluation de l'implantation d'un réseau de services intégrés pour personnes âgées en perte d'autonomie dans deux secteurs de Montréal (Québec), cet article se propose d'amorcer une réflexion sur l'introduction de réformes dans les systèmes de soins. Il montre l'intérêt des stratégies de changement décentralisées et participatives, basées sur l'expérimentation sociale, plus particulièrement lorsque le changement en question est complexe. En effet, cette modalité de changement confère l'autonomie nécessaire à l'initiation d'un processus d'apprentissage. En conclusion, nous formulons certaines hypothèses concernant les facteurs de succès de ces expérimentations sociales.Introducir el cambio en los sistemas de asistencia en Québec: comó obtener beneficios de la experimentación social ? Este artículo se propone iniciar una reflexión sobre la introducción de reformas en los sistemas asistenciales basándose en la evaluación de de una red de servicios integrados para ancianos que van perdiendo la autonomia, implantada en dos sectores de Montréal (Québec). Muestra la importacia de las estrategias descentralizadas y participativas, basadas en la experimentación social, en particular cuando el cambio en cuestión es complejo. En efecto, esta modalidad de cambio confiere la autonomia necesaria para el comienzo de un proceso de aprendizaje. En conclusión, formulamos ciertas hipótesis en relación a los factores de éxito de estas experimentaciones sociales.Touati Nasséra, Denis Jean-Louis, Contandriopoulos André-Pierre, Béland François. Introduire le changement dans les systèmes de soins au Québec : comment tirer profit de l'expérimentation sociale ?. In: Sciences sociales et santé. Volume 23, n°2, 2005. pp. 75-102