Association of hypoadiponectemia with smokeless/dipping tobacco use in young men

Background: Low levels of adiponectin, an adipocytokine with anti-diabetic, antiatherogenic and cardioprotective properties, is associated with increased risk of coronary disease in young men. Previous studies have demonstrated that smokeless tobacco is linked with a reduction of plasma adiponectin levels. However, the influence of smokeless tobacco (dipping tobacco) on plasma adiponectin levels still remains unknown. This study was conducted to assess the plasma adiponectin levels in young men who were using dipping tobacco. Methods: This was a community based study, which consisted of 186 young lean healthy males aged 20 to 35 years. Among these, 96 men were dipping tobacco users (BMI = 23.07 ± 2.68) and 90 were non-dipping tobacco users (BMI = 23.67 ± 1.46). Serum adiponectin levels were assessed by Enzyme Linked ImmunoSorbent Assay (ELISA). Results: A statistically significant difference in the mean adiponectin level between tobacco dipper and non-dipper groups was observed (p = 0.0001). A significant difference between the two groups was also observed in baseline parameters including triglyceride and random blood sugar levels (p < 0.05). However, no significant difference was observed between the two groups in other clinical parameters. Conclusions: Findings of this study suggest that dipping tobacco use was significantly associated with low level of adiponetin in community dwelling young males. This emphasizes the importance of developing community intervention to reduce the use of dipping tobacco, which will reduce the tobacco associated disease burden in the community and will improve public health

Assessment of Hearing Loss by Audiometry - Our Experience at Tertiary Care Hospital

Objective: To analyze the results of pure tone audiometry in the terms of age, sex, and type of hearing loss attending the hospital with the complaint of hearing loss. Materials and Methods: In this descriptive study, patients attending Benazir Bhutto hospital with complaints of hearing loss were included. The data analysis was done under the terms of age, sex and unilateral/bilateral, and type of loss after pure tone audiometry of every case. The type of hearing loss was determined as conductive, SNHL, and mixed hearing loss. Results: There were 47 patients. Males were 34 (72.34%) outnumbering13females 13(27.66). Adults were44 (93.61%) and children were 3(6.34%). Mixed hearing loss was28 (59.57%)% compared to conductive hearing loss 15 (31.91) and SNHL4 (8.51%). Conclusion: Hearing loss is more common in adults and more prevalent in males. It is mostly bilateral. Mixed hearing loss is more common as compared to conductive and SNHL respectively. Sociacusis is to be taken seriously. &nbsp

Mitigating potential of polystyrene microplastics on bioavailability, uptake, and toxicity of copper in maize (Zea mays L.)

Acknowledgments This study received no grant from funding organizations in the public, private, or not-for-profit sectors.Peer reviewe

Mechanical performance of concrete reinforced with polypropylene fibers (PPFs)

[EN] Fibers are one of the most prevalent methods to enhance the tensile capacity of concrete. Most researchers focus on steel fiber reinforced concrete which is costly and easily corroded. This study aims to examine the performance of polypropylene fiber reinforced concrete through different tests. PPFs were added into concrete blends in a percentage of 1.0%, 2.0%, 3.0%, and 4.0% by weight of cement to offset its objectionable brittle nature and improve its tensile capacity. The fresh property was evaluated through slump cone test and while mechanical strength was evaluated through compressive strength, split tensile strength flexure strength, and flexure cracking behaviors after 7-, 14-, and 28-days curing. Results indicate that slump decrease with the addition of PPFs while fresh density increase up to 2.0% in addition to PPFs and then decreases. Similarly, strength (compressive strength; split tensile strength, and flexure strength) was increased up to 2.0% addition of PPFs and then decrease gradually. It also suggests that Ductility; first crack load, maximum crack width, and load-deflection inter-relations were considerably improved due to incorporations of PPFs.SIThe author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: Deanship of Scientific Research at King Khalid University for funding this work through group research program under grant number RGP. 2 /71/42

Prevalence and Molecular Diagnosis of Fasciola hepatica in Sheep and Goats in Different Districts of Punjab, Pakistan

A study was conducted to determine the prevalence and molecular diagnosis of fasciolosis in Lohi sheep and Beetal goats in Okara, Sahiwal and Lahore districts of Punjab province. A total of 800 samples including 200 fecal and 200 bile, each from Lohi sheep and Beetal goats were collected and processed for microscopic examination of Fasciola eggs as well as its confirmation through polymerase chain reaction (PCR). Of the fecal samples, 3.5 and 2% samples whereas from bile samples, 6.5 and 4% bile samples from sheep and goats were found microscopically positive for Fasciola hepatica, respectively. By PCR, 4.5 and 3.5% fecal samples and 8.5 and 5% bile samples from sheep and goats, respectively were confirmed for F. hepatica. Statistically sheep and goats species were found equally likely acquiring the F. hepatica diagnosed by either source of material (fecal and bile samples) similarly fecal and bile samples were equally likely showing fasciolosis in either of sheep and goats

Mechanical properties and durability assessment of nylon fiber reinforced self-compacting concrete

[EN] The higher paste volume in Self Compacting Concrete (SCC) makes it susceptible to have a higher creep coefficient and cracking and has brittle nature. This brittle nature of concrete is unacceptable for any construction industry. The addition of fibers is one of the most prevalent methods to enhance the ductile and tensile behavior of concrete. Fibers reduce the cracking phenomena and improve the energy absorption capacity of the structure. Conversely, the addition of fibers has a negative impact on the workability of fresh concrete. In this research work, a detailed investigation of the influence of Nylon fibers (NFs) on fresh properties, durability, and mechanical properties of SCC was carried out. NFs were added into concrete mixes in a proportion of 0.5%, 1%, 1.5%, and 2% by weight of cement to achieve the research objectives. Durability assessment of modified SCC having Nylon fibers was performed using water absorption, permeability, carbonation resistance, and acid attack resistant. Mechanical tests (compressive and tensile) were conducted for modified as well as control mix. Test results indicate that the passing and filling ability decreased while segregation and bleeding resistance increased with NFs. Furthermore, test results showed a significant increase in strength up to 1.5% addition of nylon fibers and then strength decreases gradually. Durability parameters were significantly improved with the incorporation of NFs relative to the control mix. Overall, this study demonstrated the potential of using nylon fibers in self-compacting concrete with improved durability and mechanical properties.SIThe author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: The authors extend their appreciation to the Deanship of Scientific Research at King Khalid University for funding this work through group research program under grant number RGP. 1/100/42 and Taif University Researchers Supporting Project (number TURSP- 2020/276), Taif University, Taif, Saudi Arabi

Suitability of various plant derived gelling agents as agar substitute in microbiological growth media

Eleven putative gelling agents were investigated as agar substitutes. These included arrowroot (Maranta arundinaceae), coconut powder (Cocos nucifera), corn flour (Zea mays var. amylacea), gel rite (a water-soluble polysaccharide produced by Sphingomonas elodea), glue (Cyanoacrylates), katira gum (Cochlospermum religiosum), guar gum (Cyamopsis tetragonolobus L.), isubgol husk (Plantago ovata), pectin and rice (Oryza sativa L.) powder. Among these, guar gum was found a promising alternate candidate for agar. Media solidified with 2.8% guar gum was transparent and supportive for the growth of three test fungi (Trichoderma harzianum, Alternaria alternata and Alternaria solani) as good as agar. Guar gum also excelled in terms of cost benefit ratio when compared with agar. Guar gum fortified media was found to cost $0.005/L as compared to agar supplemented media costing$ 1.17/L. Further, guar gum is easily available and can be added with ease thereby serving as a suitable and inexpensive substitute of agar and thus, can be adopted for routine microbiological testing in resource poor countries.Key words: Guar gum, media, agar, gelling agents

Friction and wear performance evaluation of bio-lubricants and DLC coatings on cam/tappet interface of internal combustion engines

The environmental concerns associated with artificially formulated engine oils have forced a shift towards bio-based lubricants. The deposition of hard coatings on engine components and migrating to environmentally friendly green lubricants can help in this regard. Chemically modified forms of vegetable oils, with better low-temperature characteristics and enhanced thermo-oxidative stability, are suitable substitutes to conventional lubricant base oils. The research presented in this manuscript was undertaken to experimentally investigate the wear and friction performance of a possible future generation of an environmentally friendly bio-based lubricant as a potential replacement for conventional engine lubricants. In order to quantify the tribological benefits which can be gained by the deposition of DLC coatings, (an (a-C:H) hydrogenated DLC coating and an (a-C:H:W) tungsten-doped DLC coating) were applied on the cam/tappet interface of a direct acting valve train assembly of an internal combustion engine. The tribological correlation between DLC-coated engine components, lubricant base oils and lubricant additives have been thoroughly investigated in this study using actual engine operating conditions. Two additive-free base oils (polyalphaolefines (PAO) and chemically-modified palm oil (TMP)) and two multi-additive-containing lubricants were used in this investigation. Real-time drive torque was measured to determine the friction force, detailed post-test analysis was performed, which involved the use of a specialized jig to measure camlobe wear. An optical profilometer was used to measure the wear on the tappet, high-resolution scanning electron microscopy was employed to study the wear mechanism and energy-dispersive X-ray spectroscopy was performed on the tested samples to qualitatively access the degradation of the coating. When using additive-free TMP, a low friction coefficient was observed for the cam/tappet interface. The presence of additives further improved the friction characteristics of TMP, resulting in reduced average friction torque values. A tremendous enhancement in wear performance was recorded with a-C:H-coated parts and the coating was able to withstand the test conditions with little or no delamination

Friction and Wear Performance Evaluation of Bio-Lubricants and DLC Coatings on Cam/Tappet Interface of Internal Combustion Engines

The environmental concerns associated with artificially formulated engine oils have forced a shift towards bio-based lubricants. The deposition of hard coatings on engine components and migrating to environmentally friendly green lubricants can help in this regard. Chemically modified forms of vegetable oils, with better low-temperature characteristics and enhanced thermo-oxidative stability, are suitable substitutes to conventional lubricant base oils. The research presented in this manuscript was undertaken to experimentally investigate the wear and friction performance of a possible future generation of an environmentally friendly bio-based lubricant as a potential replacement for conventional engine lubricants. In order to quantify the tribological benefits which can be gained by the deposition of DLC coatings, (an (a-C:H) hydrogenated DLC coating and an (a-C:H:W) tungsten-doped DLC coating) were applied on the cam/tappet interface of a direct acting valve train assembly of an internal combustion engine. The tribological correlation between DLC-coated engine components, lubricant base oils and lubricant additives have been thoroughly investigated in this study using actual engine operating conditions. Two additive-free base oils (polyalphaolefines (PAO) and chemically-modified palm oil (TMP)) and two multi-additive-containing lubricants were used in this investigation. Real-time drive torque was measured to determine the friction force, detailed post-test analysis was performed, which involved the use of a specialized jig to measure camlobe wear. An optical profilometer was used to measure the wear on the tappet, high-resolution scanning electron microscopy was employed to study the wear mechanism and energy-dispersive X-ray spectroscopy was performed on the tested samples to qualitatively access the degradation of the coating. When using additive-free TMP, a low friction coefficient was observed for the cam/tappet interface. The presence of additives further improved the friction characteristics of TMP, resulting in reduced average friction torque values. A tremendous enhancement in wear performance was recorded with a-C:H-coated parts and the coating was able to withstand the test conditions with little or no delamination