A longitudinal study on the promotion of acquisition processes in the EFL classroom: theoretical proposals and practical implications

The framework that Relevance Theory offers for the description of the internal processes involved in comprehension, and its incorporation into SLA studies by Haidl (1993), enable this author to present a range of innovatory methodological guidelines aiming to achieve acquisition in the FL classroom. Following these guidelines, the longitudinal study which we report here aims to test the development of acquisition in that context. The results show the practicality of the project and reveal the possible incompatibility of combining acquisition and learning processes in the classroom if it is not approached from a consistent theoretical basis.El marco que ofrece la Teoría de la Relevancia para describir los procesos internos que intervienen en la comprensión y su incorporación a los estudios de ASL por Haidl (1993) permiten a este autor presentar una serie de orientaciones metodológicas para generar adquisición en el aula de LE. Siguiéndolas, el estudio longitudinal que aquí comentamos intenta desarrollar adquisición en el aula de la ESO. Los resultados muestran la practicidad del proyecto y revelan la posible incompatibilidad de combinar en el aula procesos de adquisición y aprendizaje si el recurso a la reflexión consciente no se aborda desde bases teóricas consecuentes

Vitamin D3 Receptor (VDR) Gene rs2228570 (Fok1) and rs731236 (Taq1) Variants Are Not Associated with the Risk for Multiple Sclerosis: Results of a New Study and a Meta-Analysis

Background: Some epidemiological, genetic, and experimental data suggest a possible role of vitamin D in the pathogenesis of multiple sclerosis (MS) and in experimental autoimmune encephalomyelitis. Data on the possible contribution of several single nucleotide polymorphisms (SNP) in the vitamin D receptor (VDR) gene to the risk for MS are controversial. Several studies suggested an interaction between some SNPs in the VDR gene and HLADRB1*1501 in the risk for MS. Objectives: The aim of this study was to investigate a possible influence of the SNPs rs2228570 and rs731236 in the VDR gene in the risk for MS. A secondary objective was to address the possible interactions between VDR genes and HLADRB1*1501. Methods: We analyzed the allelic and genotype frequency of VDR rs2228570, rs731236, and HLADRB1*1501 (rs3135388) in 303 patients with MS and 310 healthy controls, using TaqMan Assays. We also conducted a meta-analysis, that was carried out by using the software Meta-Disc 1.1.1 (http://www.hrc.es/investigacion/metadisc.html; Unit of Clinical Statistics, Hospital Ramon y Cajal, Madrid, Spain). Heterogeneity between studies in terms of degree of association was tested using the Q-statistic. Results: VDR rs2228570 and rs731236 allelic and genotype frequencies did not differ significantly between MS patients and controls, and were unrelated with the age of onset of MS, gender, and course of MS. HLADRB1*1501 showed a high association with the risk of developing MS 4.76(95% C. I. = 3.14-7.27; p<0.0001). The meta-analysis, after excluding data of one study that was responsible of heterogeneity for rs731236 polymorphism, showed lack of relation of both SNPs with the risk for MS. HLADRB1*1501 showed lack of interaction with VDR rs2228570 and rs731236 in increasing MS risk. Conclusions: These results suggest that VDR rs2228570 and rs731236 polymorphisms are not related with the risk for MS, and did not confirm interaction between these VDR SNPs and HLADRB1 in the risk for MS.This work was supported in part by Grants FIS PS09/00943, PS09/00469, and RETICS RD07/0064/0016 from Fondo de Investigación Sanitaria, Instituto de Salud Carlos III, Spain, and GR10068 from Junta de Extremadura, Spain.Peer Reviewe

Con ganas de matar

“Con ganas de matar” se trata de una historia de rutina y de cómo esta puede ser muy peligrosa. La rutina rompe parejas, enfría relaciones, nos aburre e incluso, en ocasiones muy extremas, alimentan las ganas de matar.Universidad de Sevilla. Máster en Guión, Narrativa y Creatividad Audiovisua

Ajedrez medieval y la figura de la dama en Repetición de amores y arte de ajedrez en 150 juegos de partido de Luis Ramírez de Lucena

Trabajo de fin de Grado. Grado en Filología Hispánica. Curso académico 2021-2022Este trabajo se centra en el incunable de Luis Ramírez de Lucena, ajedrecista y autor de Repetición de amores y Arte de ajedrez en 150 juegos de partido, dando un contexto histórico general sobre el ajedrez durante la Edad Media, la mujer medieval y el ajedrez, y la aparición por primera vez de un tratado de ajedrez moderno.This paper focuses on the incunabulum of Luis Ramírez de Lucena, chess player and author of Repetición de amores y Arte de ajedrez en 150 juegos de partido, giving a general historical context about chess during the Middle Ages, medieval women and chess, and the appearance for the first time of a modern chess treatise

Coordinating heterogeneous IoT devices by means of the centralized vision of the SDN controller

The IoT (Internet of Things) has become a reality during recent years. The desire of having everything connected to the Internet results in clearly identified benefits that will impact on socio economic development. However, the exponential growth in the number of IoT devices and their heterogeneity open new challenges that must be carefully studied. Coordination among devices to adapt them to their users' context usually requires high volumes of data to be exchanged with the cloud. In order to reduce unnecessary communications and network overhead, this paper proposes a novel network architecture based on the Software-Defined Networking paradigm that allows IoT devices coordinate and adapt them within the scope of a particular context.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Analysis of the relationship between coastal development and the alteration of beach shorelines: a retrospective view based on spatial indicators

The construction of port infrastructures in urbanized coastal territories causes a great impact in the short and long term. The analysis of this impact is a very complex field due to the high number of variables involved. The criteria for analyzing these phenomena are usually based on the characteristics of the infrastructure to be built, but in the case of highly urbanized areas, there are other variables that are not normally taken into account. With the aim of giving an alternative approach to traditional analysis methods and relating the maximum number of possible variables, our study is given a multiparametric and retrospective approach based on GIS indicators. For this, the coastal area of the southeast of Spain is analyzed with the cartographic information that we have from the last 50 years. The changes suffered in the coastline caused by the construction of ports are analyzed in two dimensions and the statistical correlation of the different variables studied and the impact suffered on the coast are studied, such as the formation of tombolos and hemitombolos or salients, as well as coastal regression, even generation of sludge due to imbalances in sedimentary dynamics. The results can be used to enrich and improve the traditional analysis models for singular cases such as those studied

Thr105Ile (rs11558538) polymorphism in the histamine N-methyltransferase (HNMT) gene and risk for Parkinson disease A PRISMA-compliant systematic review and meta-analysis

Background/aims: Several neuropathological, biochemical, and pharmacological data suggested a possible role of histamine in the etiopathogenesis of Parkinson disease (PD). The single nucleotide polymorphism (SNP) rs11558538 in the histamine Nmethyltransferase (HNMT) gene has been associated with the risk of developing PD by several studies but not by some others. We carried out a systematic review that included all the studies published on PD risk related to the rs11558538 SNP, and we conducted a meta-analysis following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Methods: We used several databases to perform the systematic review, the software Meta-DiSc 1.1.1 to perform the metaanalysis of the eligible studies, and the Q-statistic to test heterogeneity between studies. Results: The meta-analysis included 4 eligible case–control association studies for the HNMT rs11558538 SNP and the risk for PD (2108 patients, 2158 controls). The frequency of the minor allele positivity showed a statistically significant association with a decreased risk for PD, both in the total series and in Caucasians. Although homozygosity for the minor allele did not reach statistical significance, the test for trend indicates the occurrence of a gene–dose effect. Global diagnostic odds ratios (95% confidence intervals) for rs11558538T were 0.61 (0.46–0.81) for the total group, and 0.63 (0.45–0.88) for Caucasian patients. Conclusion: The present meta-analysis confirms published evidence suggesting that the HNMT rs11558538 minor allele is related to a reduced risk of developing PD.Trabajo financiado por: Instituto de Salud Carlos III. Fondo de Investigación Sanitaria. Ayudas PI12/00241, PI12/00324, PI15/00303 y RETICS RD12/0013/0002 Junta de Extremadura y Fondos FEDER. Ayuda GR15026peerReviewe

Análisis de respuestas libres en los cuestionarios. El método de las especificidades

Frente a las cuestiones cerradas, el empleo de preguntas abiertas en los cuestionarios ofrece el problema de la dificultad en el análisis de las respuestas. Generalmente, el análisis que suele realizarse de éstas se basa en procesos de postcodificación, que conllevan un considerable coste en esfuerzo y tiempo, además de suponer una reducción de la información y estar afectados por la subjetividad del codificador. Como alternativa, en este artículo presentamos el método de las especificidades, una técnica enmarcada en el contexto de la estadística textual, que permite el análisis de respuestas libres de manera rápida y eficaz. Ilustramos este método aplicándolo al análisis de los datos obtenidos mediante un cuestionario en el que se incluía una pregunta abierta junto a varias cuestiones cerradas.Faced to the closed questions, the use of open-end questions in the questionnaires show the problem of difficulty in the analysis of date. Generally, the analysis is based on postcodification process, wich imply an important cost on time and effort. It will also suppose a reduction of information and if could be affected by the analyst subjectivity. As alternative, we show the calculation of lexical specifications. It is a technique included in the context of the textual statistics, for processing answers to open-end questions in a fast and effective way. We apply this method to the analysis of the data obtained trough a questionnaire in which an openend question follow-up to closed question