11 research outputs found

    Las implicaciones políticas de la relación China-América Latina: el Consenso Asiático como red de poder global y el caso brasileño (Tema Central)

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    This paper analyzes the People’s Republic of China economic and political ascendance in the 21st century, focusing on the evolution of its sui géneris economic development model and its significance for the relationship between China and the developing countries of the peripheral ‘Global South.’ The objective of this article is to analyze the relationship between China and Latin America in the 21st century, characterizing it as a new Center-periphery global power network based on trade and investment, which is often referred to as the ‘Asian Consensus’. The article will give special attention to the Brazilian case.Este artículo pretende analizar la ascensión económica y política de la República Popular de China (RPC) en el siglo XXI enfocando, específicamente, la evolución de su modelo de desarrollo sui géneris y sus implicaciones en los países periféricos del sistema capitalista, o del “Sur Global”. El objetivo de este artículo es analizar la relación China-América Latina en el siglo XXI como conformación de una nueva red de poder global basada en la interdependencia comercial y de inversiones, cuyo resultado es la ‘relocalización’ de América Latina en la división internacional del trabajo y la producción, constituyendo una reformulación de una relación centro-periferia que denominamos: ‘Consenso Asiático’. El artículo realizará un especial enfoque en el caso de Brasil

    Brazil's role in Latin America's regionalism unilateral and lonely international engagement

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    At the beginning of the twenty-first century, Brazil became a crucial player as the principal advocate of South American integration. To Mercado Común del Sur (Mercosur) was added the Union of South American Nations (UNASUR), reaffirming regional policies around the idea of "South America."Today, however, the withdrawal of Brazilian leadership along with the reversals and loss of focus in UNASUR and Mercosur have damaged the credibility of the region's initiatives, as well as finding South America's common voice. Despite this, this article argues that Brazil has not entirely disengaged from the region or abandoned the principle of regionalism. Recognition of Latin America's distinctive history the authors to construct a model that incorporates complexity and disorder in which Brazil's institutional political development will have significant repercussions for the future of the region.Fil: Vadell, Javier A.. Pontifícia Universidade Católica de Minas Gerais; BrasilFil: Giaccaglia, Clarisa. Universidad Nacional de Córdoba. Facultad de Cs.politicas y Rel.internacionales; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario; Argentin

    Combined in Vitro Cell-Based/in Silico Screening of Naturally Occurring Flavonoids and Phenolic Compounds as Potential Anti-Alzheimer Drugs

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    Alzheimer’s disease (AD) is the main cause of dementia in people over 65 years. One of the major culprits in AD is the self-aggregation of amyloid-β peptide (Aβ), which has stimulated the search for small molecules able to inhibit Aβ aggregation. In this context, we recently reported a simple, but effective in vitro cell-based assay to evaluate the potential antiaggregation activity of putative Aβ aggregation inhibitors. In this work this assay was used together with docking and molecular dynamics simulations to analyze the anti-Aβ aggregation activity of several naturally occurring flavonoids and phenolic compounds. The results showed that rosmarinic acid, melatonin, and <i>o</i>-vanillin displayed zero or low inhibitory capacity, curcumin was found to have an intermediate inhibitory potency, and apigenin and quercetin showed potent antiaggregation activity. Finally, the suitability of the combined in vitro cell-based/in silico approach to distinguish between active and inactive compounds was further assessed for an additional set of flavonols and dihydroflavonols
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