2,590 research outputs found

    On finite-temperature holographic QCD in the Veneziano limit

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    Holographic models in the T=0 universality class of QCD in the limit of large number N_c of colors and N_f massless fermion flavors, but constant ratio x_f=N_f/N_c, are analyzed at finite temperature. The models contain a 5-dimensional metric and two scalars, a dilaton sourcing TrF^2 and a tachyon dual to \bar qq. The phase structure on the T,x_f plane is computed and various 1st order, 2nd order transitions and crossovers with their chiral symmetry properties are identified. For each x_f, the temperature dependence of p/T^4 and the quark-antiquark -condensate is computed. In the simplest case, we find that for x_f up to the critical x_c\sim 4 there is a 1st order transition on which chiral symmetry is broken and the energy density jumps. In the conformal window x_c<x_f<11/2, there is only a continuous crossover between two conformal phases. When approaching x_c from below, x_f\to x_c, temperature scales approach zero as specified by Miransky scaling.Comment: 66 pages, 29 figure

    Stellar activity as noise in exoplanet detection I. Methods and application to solar-like stars and activity cycles

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    The detection of exoplanets using any method is prone to confusion due to the intrinsic variability of the host star. We investigate the effect of cool starspots on the detectability of the exoplanets around solar-like stars using the radial velocity method. For investigating this activity-caused "jitter" we calculate synthetic spectra using radiative transfer, known stellar atomic and molecular lines, different surface spot configurations, and an added planetary signal. Here, the methods are described in detail, tested and compared to previously published studies. The methods are also applied to investigate the activity jitter in old and young solar-like stars, and over a solar-like activity cycles. We find that the mean full jitter amplitude obtained from the spot surfaces mimicking the solar activity varies during the cycle approximately between 1 m/s and 9 m/s. With a realistic observing frequency a Neptune mass planet on a one year orbit can be reliably recovered. On the other hand, the recovery of an Earth mass planet on a similar orbit is not feasible with high significance. The methods developed in this study have a great potential for doing statistical studies of planet detectability, and also for investigating the effect of stellar activity on recovered planetary parameters.Comment: Accepted to MNRA

    Matrix representations, linear transformations, and kernels for disambiguation in natural language

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    In the application of machine learning methods with natural language inputs, the words and their positions in the input text are some of the most important features. In this article, we introduce a framework based on a word-position matrix representation of text, linear feature transformations of the word-position matrices, and kernel functions constructed from the transformations. We consider two categories of transformations, one based on word similarities and the second on their positions, which can be applied simultaneously in the framework in an elegant way. We show how word and positional similarities obtained by applying previously proposed techniques, such as latent semantic analysis, can be incorporated as transformations in the framework. We also introduce novel ways to determine word and positional similarities. We further present efficient algorithms for computing kernel functions incorporating the transformations on the word-position matrices, and, more importantly, introduce a highly efficient method for prediction. The framework is particularly suitable to natural language disambiguation tasks where the aim is to select for a single word a particular property from a set of candidates based on the context of the word. We demonstrate the applicability of the framework to this type of tasks using context-sensitive spelling error correction on the Reuters News corpus as a model problem

    An efficient algorithm for learning to rank from preference graphs

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    In this paper, we introduce a framework for regularized least-squares (RLS) type of ranking cost functions and we propose three such cost functions. Further, we propose a kernel-based preference learning algorithm, which we call RankRLS, for minimizing these functions. It is shown that RankRLS has many computational advantages compared to the ranking algorithms that are based on minimizing other types of costs, such as the hinge cost. In particular, we present efficient algorithms for training, parameter selection, multiple output learning, cross-validation, and large-scale learning. Circumstances under which these computational benefits make RankRLS preferable to RankSVM are considered. We evaluate RankRLS on four different types of ranking tasks using RankSVM and the standard RLS regression as the baselines. RankRLS outperforms the standard RLS regression and its performance is very similar to that of RankSVM, while RankRLS has several computational benefits over RankSVM

    Clinical findings in relation to mortality in non-tuberculous mycobacterial infections : patients with Mycobacterium avium complex have better survival than patients with other mycobacteria

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    We compared the clinical findings and survival in patients with Mycobacterium avium complex (MAC) and other non-tuberculous mycobacteria (NTM). A total of 167 adult non-human immunodeficiency virus (HIV) patients with at least one positive culture for NTM were included. Medical records were reviewed. The patients were categorised according to the 2007 American Thoracic Society (ATS) criteria. MAC comprised 59 % of all NTM findings. MAC patients were more often female (70 % vs. 34 %, p <0.001) and had less fatal underlying diseases (23 % vs. 47 %, p = 0.001) as compared to other NTM patients. Symptoms compatible with NTM infection had lasted for less than a year in 34 % of MAC patients but in 54 % of other NTM patients (p = 0.037). Pulmonary MAC patients had a significantly lower risk of death compared to pulmonary other NTM (hazard ratio [HR] 0.50, 95 % confidence interval [CI] 0.33-0.77, p = 0.002) or subgroup of other slowly growing NTM (HR 0.55, 95 % CI 0.31-0.99, p = 0.048) or as rapidly growing NTM (HR 0.47, 95 % CI 0.25-0.87, p = 0.02). The median survival time was 13.0 years (95 % CI 5.9-20.1) for pulmonary MAC but 4.6 years (95 % CI 3.4-5.9) for pulmonary other NTM. Serious underlying diseases (HR 3.21, 95 % CI 2.05-5.01, p <0.001) and age (HR 1.07, 95 % CI 1.04-1.09, p <0.001) were the significant predictors of mortality and female sex was a predictor of survival (HR 0.38, 95 % CI 0.24-0.59, p <0.001) in the multivariate analysis. Pulmonary MAC patients had better prognosis than pulmonary other NTM patients. The symptom onset suggests a fairly rapid disease course.Peer reviewe

    Treatment of keloid scars with intralesional triamcinolone and 5-fluorouracil injections - a randomized controlled trial

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    Keloids have high recurrence rates. Current first-line therapy is triamcinolone (TAC) injection, but it has been suggested that approximately 50% of keloids are steroid resistant. We compared the efficacy of intralesional 5-fluorouracil (5-FU) and triamcinalone injections in a double-blind randomized controlled trial. Forty-three patients with 50 keloid scars were treated with either intralesional TAC or 5-FU-injections over 6 months. There was no statistically significant difference in the remission rate at 6 months between the 5-FU and TAC groups (46% vs 60%, respectively). Local adverse effects were higher in the TAC group compared to the 5-FU group. Occurrence of skin atrophy in TAC group was 44% and in the 5-FU group 8% (p <0.05). Also the occurrence of telangiectasia in the TAC group was 50% and in the 5-FU 21% (p <0.05). Vascularity of the keloids, assessed by spectral imaging and immunohistochemical staining for blood vessels, after treatment decreased in the TAC group, but not in the 5-FU group (p <0.05). Fibroblast proliferation evaluated by Ki-67 staining significantly decreased in the TAC group (p <0.05) but increased in the 5-FU group (p <0.05). TAC and 5-FU injections did not differ in their clinical effectivity in this randomized study, but 5-FU injections lead to increased proliferation rate and did not affect vascular density in histological assessment. Due to the greater number of adverse effects observed after TAC treatment, 5-FU injections may be preferable for cosmetically sensitive skin areas. (C) 2018 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.Peer reviewe
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