1,980 research outputs found
YoeB toxin is activated during thermal stress.
Type II toxin-antitoxin (TA) modules are thought to mediate stress-responses by temporarily suppressing protein synthesis while cells redirect transcription to adapt to environmental change. Here, we show that YoeB, a ribosome-dependent mRNase toxin, is activated in Escherichia coli cells grown at elevated temperatures. YoeB activation is dependent on Lon protease, suggesting that thermal stress promotes increased degradation of the YefM antitoxin. Though YefM is efficiently degraded in response to Lon overproduction, we find that Lon antigen levels do not increase during heat shock, indicating that another mechanism accounts for temperature-induced YefM proteolysis. These observations suggest that YefM/YoeB functions in adaptation to temperature stress. However, this response is distinct from previously described models of TA function. First, YoeB mRNase activity is maintained over several hours of culture at 42°C, indicating that thermal activation is not transient. Moreover, heat-activated YoeB does not induce growth arrest nor does it suppress global protein synthesis. In fact, E. coli cells proliferate more rapidly at elevated temperatures and instantaneously accelerate their growth rate in response to acute heat shock. We propose that heat-activated YoeB may serve a quality control function, facilitating the recycling of stalled translation complexes through ribosome rescue pathways
Characteristics of Farm Reorganization Bankruptcy Filings
Although agricultural financial conditions and reorganization options have been analyzed extensively by agricultural economists, an analysis of actual Chapter 11 bankruptcy filing has not previously been completed. This study contains analysis of actual Chapter 11 bankruptcy filings has not previously been completed. This study contains analysis of 219 filings in South Dakota from 1980-85 and documents the financial characteristics of producers and creditors
Determinants of Salary Dispersion among Political Science Faculty: The Differential Effects of Where You Work (Institutional Characteristics) and What You Do (Negotiate and Publish)
We evaluate hypotheses about human capital and structural theory-based predictors of variation in academic salaries. We use standard statistical models to explore differences in salary among full-time political science faculty, while also utilizing selection models to control for factors that place individuals on different trajectories stemming from their graduate school experience. We report on several findings, one of which is the positive effect on salary associated with graduation from a highly ranked PhD program; a second being the negative effect on salary of a high undergraduate teaching load. Other findings are that negotiation positively affects salary for men, but not for women, and that journal publications increase salaries amongst women, but not men. At the associate professor level, we find a significant gender gap in salary, even with controls for human capital, structural factors, and productivity. We also find a significant effect of race on the salaries of male faculty
Pressure and Motion of Dry Sand -- Translation of Hagen's Paper from 1852
In a remarkable paper from 1852, Gotthilf Heinrich Ludwig Hagen measured and
explained two fundamental aspects of granular matter: The first effect is the
saturation of pressure with depth in a static granular system confined by silo
walls -- generally known as the Janssen effect. The second part of his paper
describes the dynamics observed during the flow out of the container -- today
often called the Beverloo law -- and forms the foundation of the hourglass
theory. The following is a translation of the original German paper from 1852.Comment: 4 pages, accepted for publication in Granular Matter, original
article (German) can be found under http://www.phy.duke.edu/~msperl/Janssen
Soil and crop response to stover removal from rainfed and irrigated corn
Excessive corn (Zea mays L.) stover removal for biofuel and other uses may adversely impact soil and crop production. We assessed the effects of stover removal at 0, 25, 50, 75, and 100% from continuous corn on water erosion, corn yield, and related soil properties during a 3-year study under irrigated and no-tillage management practice on a Ulysses silt loam at Colby, irrigated and strip till management practice on a Hugoton loam at Hugoton, and rainfed and no-tillage management practice on a Woodson silt loam at Ottawa in Kansas, USA. The slope of each soil was \u3c1%. One year after removal, complete (100%) stover removal resulted in increased losses of sediment by 0.36–0.47 Mg ha-1 at the irrigated sites, but, at the rainfed site, removal at rates as low as 50% resulted in increased sediment loss by 0.30 Mg ha-1 and sediment-associated carbon (C) by 0.29 kg ha-1. Complete stover removal reduced wet aggregate stability of the soil at the irrigated sites in the first year after removal, but, at the rainfed site, wet aggregate stability was reduced in all years. Stover removal at rates ≥ 50%resulted in reduced soil water content, increased soil temperature in summer by 3.5–6.8 °C, and reduced tem-perature in winter by about 0.5 °C. Soil C pool tended to decrease and crop yields tended to increase with an increase in stover removal, but 3 years after removal, differences were not significant. Overall, stover removal at rates ≥50% may enhance grain yield but may increase risks of water erosion and negatively affect soil water and temperature regimes in this region
An adaptive agent model for analysing co-evolution of management and policies in a complex rangeland system
This paper describes an adaptive agent model of rangelands based on concepts of complex adaptive systems. The behavioural and biological processes of pastoralists, regulators, livestock, grass and shrubs are modelled as well as the interactions between these components. The evolution of the rangeland system is studied under different policy and institutional regimes that affect the behaviour and learning of pastoralists, and hence the state of the ecological system. Adaptive agent models show that effective learning and effective ecosystem management do not necessarily coincide and can suggest potentially useful alternatives to the design of policies and institutions. (C) 2000 Elsevier Science B.V
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