Modelling of Electric Traction Vehicles with Regard to the Power Quality and Dynamics of Operation

The article deals with modelling of traction vehicles being operated in the Czech Republic in the 25 kV/50 Hz power system with respect to their consumption quality and power consumption. Models of typical locomotive categories, sorted according to their electrical equipment and typical power quality, were created in PSCAD . The models are able to simulate the locomotives dynamical operation up to the detail of power quality

Using component ensembles for modeling autonomic component collaboration in smart farming

Smart systems have become key solutions for many application areas including autonomous farming. The trend we can see now in the smart systems is that they shift from single isolated autonomic and self-adaptive components to larger ecosystems of heavily cooperating components. This increases the reliability and often the cost-effectiveness of the system by replacing one big costly device with a number of smaller and cheaper ones. In this paper, we demonstrate the effect of synergistic collaboration among autonomic components in the domain of smart farming---in particular, the use-case we employ in the demonstration stems from the AFarCloud EU project. We exploit the concept of autonomic component ensembles to describe situation-dependent collaboration groups (so called ensembles). The paper shows how the autonomic component ensembles can easily capture complex collaboration rules and how they can include both controllable autonomic components (i.e. drones) and non-controllable environment agents (flocks of birds in our case). As part of the demonstration, we provide an open-source implementation that covers both the specification of the autonomic components and ensembles of the use case, and the discrete event simulation and real-time visualization of the use case. We believe this is useful not only to demonstrate the effectiveness of architectures of collaborative autonomic components for dealing with real-life tasks, but also to build further experiments in the domain.This is the authors' version of the paper: P. Hnětynka, T. Bureš, I. Gerostathopoulos, J. Pacovský: Using Component Ensembles for Modeling Autonomic Component Collaboration in Smart Farming, in Proceedings of SEAMS 2020, Seoul, Korea, 2020. The final published version can be found at https://doi.org/10.1145/3387939.339159

Architectural Optimization for Confidentiality Under Structural Uncertainty

More and more connected systems gather and exchange data. This allows building smarter, more efficient and overall better systems. However, the exchange of data also leads to questions regarding the confidentiality of these systems. Design notions such as Security by Design or Privacy by Design help to build secure and confidential systems by considering confidentiality already at the design-time. During the design-time, different analyses can support the architect. However, essential properties that impact confidentiality, such as the deployment, might be unknown during the design-time, leading to structural uncertainty about the architecture and its confidentiality. Structural uncertainty in the software architecture represents unknown properties about the structure of the software architecture. This can be, for instance, the deployment or the actual implementation of a component. For handling this uncertainty, we combine a design space exploration and optimization approach with a dataflow-based confidentiality analysis. This helps to estimate the confidentiality of an architecture under structural uncertainty. We evaluated our approach on four application examples. The results indicate a high accuracy regarding the found confidentiality violations

Role of S100 Proteins in Colorectal Carcinogenesis

The family of S100 proteins represents 25 relatively small (9–13 kD) calcium binding proteins. These proteins possess a broad spectrum of important intracellular and extracellular functions. Colorectal cancer is the third most common cancer in men (after lung and prostate cancer) and the second most frequent cancer in women (after breast cancer) worldwide. S100 proteins are involved in the colorectal carcinogenesis through different mechanisms: they enable proliferation, invasion, and migration of the tumour cells; furthermore, S100 proteins increase angiogenesis and activate NF-κβ signaling pathway, which plays a key role in the molecular pathogenesis especially of colitis-associated carcinoma. The expression of S100 proteins in the cancerous tissue and serum levels of S100 proteins might be used as a precise diagnostic and prognostic marker in patients with suspected or already diagnosed colorectal neoplasia. Possibly, in the future, S100 proteins will be a therapeutic target for tailored anticancer therapy

spatial navigation deficit in the Morris water maze after single high dose of neonatal X-ray irradiation

ABSTRACT Ambiguous spatial behavior deficits induced in adult rats by different types of dentate gyrus lesions were examined by subjecting neonatal rats to x-ray irradiation, which reduces the granule cell population in fascia dentata without affecting the number of hilar neurons and pyramidal cells of Ammon's horn. Three-to six-month-old irradiated and intact male Long-Evans rats were tested in the Morris water maze. Four experiments were done. (i) Rats were trained to find an invisible escape platform, when started from any of four equidistant points at the circumference of the pool. (ii) The same rats then were trained to find a visible platform in the same pool. Poor performance of irradiated rats in both experiments suggested a visual deficit. (iii) Navigation in the absence of visual cues was studied in other rats trained in total darkness to find the escape platform under conditions of fixed start-fixed goal geometry. (iv) Contribution of nonvisual allocentric cues and egocentric path integration mechanisms to spatial performance of the above rats was tested in darkness after rotating both the start and goal positions by 90؇ clockwise. Impairment of irradiated rats in Exp. 3 and 4 and histological examination of their brains support the conclusion that 60-70% reduction of granule cells in the dorsal hippocampus causes significant deterioration in both allocentric and egocentric orientation

Modelling of Electric Traction Vehicles with Regard to the Power Quality and Dynamics of Operation

The article deals with modelling of traction vehicles being operated in the Czech Republic in the 25 kV/50 Hz power system with respect to their consumption quality and power consumption. Models of typical locomotive categories, sorted according to their electrical equipment and typical power quality, were created in PSCAD . The models are able to simulate the locomotives dynamical operation up to the detail of power quality