176 research outputs found
Leadership and the independent regulator
Being a utility regulator has perils because the independence of the regulator necessarily removes power from politicians, operators, and others. Furthermore, regulators are sometimes scapegoats for unpopular policies and unavoidably become involved in shaping the policies that they are supposed to implement. As a result of such frictions, regulators are sometimes removed from office or marginalized in some way. How can regulators not only survive in such an environment, but also thrive? Jamison describes a leadership concept called adaptive leadership that regulators can use to help their countries adapt to new policies and changing situations, while allowing the regulator to stay in the game. The first leadership skill he discusses is the ability to get on the balcony to see what is really going on with operators, politicians, consumers, and others. Once this perspective is obtained, then the regulator can engage stakeholders in an adaptive process in which people make necessary changes to traditions and expectations, while hanging on to the things that are truly important. Regulators can do this by bringing attention to problems that people want to ignore because they involve difficult tradeoffs, providing certainty and stability when tensions become too high for work to be done, and keeping attention focused on the work and the issues.
Effects of Industry Concentration on Quality Choices for Network Connectivity
I examine the effects of market concentration on connectivity in network
industries. Using Cournot interactions for a duopoly, each network
chooses quantity, quality for communications within the provider's own
network (internal quality), and quality for communications between the
provider's network and other networks (external quality). I find that
large networks choose higher internal quality than do small networks and
large networks choose higher internal quality than external quality. I
also find that providers prefer flexible technologies that allow them to
simultaneously choose outputs and qualities. Small networks prefer
higher external quality than internal quality except when they make
credible quality commitments before choosing output and have higher
marginal operating costs than large networks. Networks choose identical
external quality unless they have exogenously determined customer bases
Oust the Louse: Does Political Pressure Discipline Regulators?
We consider a possible determinant of regulatory decisions by public utility commissioners: the desire to remain in office. We examine regulatory exit, where a regulator leaves a commission during a term or is not re-appointed/re-elected. With data from US states, we empirically investigate several hypotheses motivated by a political agency model of regulatory decision-making. Our empirical results generally support the hypotheses, including that higher electricity prices lead to ousting, that ousting is less common where it is more costly for the principal to whom the regulator reports, and that ousting is more likely where regulators are more accountable or are more likely to share the principalâs preferences. Furthermore, the results provide limited evidence that regulatory exit is not due mainly to the revolving door. Ousting also appears to lower future electricity prices
Effects of Industry Concentration on Quality Choices for Network Connectivity
I examine the effects of market concentration on connectivity in network
industries. Using Cournot interactions for a duopoly, each network
chooses quantity, quality for communications within the provider's own
network (internal quality), and quality for communications between the
provider's network and other networks (external quality). I find that
large networks choose higher internal quality than do small networks and
large networks choose higher internal quality than external quality. I
also find that providers prefer flexible technologies that allow them to
simultaneously choose outputs and qualities. Small networks prefer
higher external quality than internal quality except when they make
credible quality commitments before choosing output and have higher
marginal operating costs than large networks. Networks choose identical
external quality unless they have exogenously determined customer bases
Complementâ induced activation of the cardiac NLRP3 inflammasome in sepsis
Cardiac dysfunction develops during sepsis in humans and rodents. In the model of polymicrobial sepsis induced by cecal ligation and puncture (CLP), we investigated the role of the NLRP3 inflammasome in the heart. Mouse heart homogenates from shamâ procedure mice contained high mRNA levels of NLRP3 and ILâ 1Ă². Usingthe inflamm a some protocol, exposure of cardiomyocytes (CMs) to LPS followed by ATP or nigericin caused release of mature ILâ 1Ă². Immuno staining of left ventricular frozen sections before and 8 h after CLP revealed the presence of NLRP3 and ILâ 1Ă² proteins inCMs. CLP caused substantial increases in mRNAs for ILâ 1Ă² and NLRP3 in CMs which are reduced in the absence of either C5aR1 or C5aR2. After CLP, NLRP32/2 mice showed reduced plasma levels of ILâ 1Ă²and ILâ 6. In vitro exposure of wildâ type CMs to recombinant C5a (rC5a) cause delevations in both cytosolic and nuclear/mitochondrial reactive oxygen species (ROS), which were C5aâ receptor dependent. Use of a selective NOX2 inhibitor prevented increased cytosolic and nuclear/mitochondrial ROS levels and release of ILâ 1Ă². Finally, NLRP32/2 mice had reduced defects in echo/Doppler parameters in heart afterCLP. These studies establish that the NLRP3 inflammasome contributes to the cardiomyopathy of polymicrobial sepsis.â Kalbitz, M., Fattahi, F., Grailer, J. J., Jajou, L., Malan, E. A., Zetoune, F. S., Huberâ Lang, M., Russell, M. W., Ward, P. A. Complementâ induced activation of the cardiac NLRP3 inflammasome in sepsis. FASEB J. 30, 3997â 4006 (2016). www.fasebj.orgPeer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/154362/1/fsb2fasebj30120728r.pd
Health gains and fi nancial risk protection aff orded by public fi nancing of selected interventions in Ethiopia: an extended cost-eff ectiveness analysis
Background The way in which a government chooses to fi nance a health intervention can aff ect the uptake of health
interventions and consequently the extent of health gains. In addition to health gains, some policies such as public
fi nance can insure against catastrophic health expenditures. We aimed to evaluate the health and fi nancial risk
protection benefi ts of selected interventions that could be publicly fi nanced by the government of Ethiopia.
Methods We used extended cost-eff ectiveness analysis to assess the health gains (deaths averted) and fi nancial risk
protection aff orded (cases of poverty averted) by a bundle of nine (among many other) interventions that the
Government of Ethiopia aims to make universally available. These nine interventions were measles vaccination,
rotavirus vaccination, pneumococcal conjugate vaccination, diarrhoea treatment, malaria treatment, pneumonia
treatment, caesarean section surgery, hypertension treatment, and tuberculosis treatment.
Findings Our analysis shows that, per dollar spent by the Ethiopian Government, the interventions that avert the most
deaths are measles vaccination (367 deaths averted per 100 000 spent), and caesarean section surgery (141 deaths averted per 100 000 spent), tuberculosis
treatment (96 cases averted per 100 000 spent).
Interpretation Our approach incorporates fi nancial risk protection into the economic evaluation of health interventions
and therefore provides information about the effi ciency of attainment of both major objectives of a health system:
improved health and fi nancial risk protection. One intervention might rank higher on one or both metrics than
another, which shows how intervention choiceâthe selection of a pathway to universal health coverageâmight
involve weighing up of sometimes competing objectives. This understanding can help policy makers to select
interventions to target specifi c policy goals (ie, improved health or fi nancial risk protection). It is especially relevant
for the design and sequencing of universal health coverage to meet the needs of poor populations
Near-island biological hotspots in barren ocean basins
Phytoplankton production drives marine ecosystem trophic-structure and global fisheries yields. Phytoplankton biomass is particularly influential near coral reef islands and atolls that span the oligotrophic tropical oceans. The paradoxical enhancement in phytoplankton near an island-reef ecosystemâIsland Mass Effect (IME)âwas first documented 60 years ago, yet much remains unknown about the prevalence and drivers of this ecologically important phenomenon. Here we provide the first basin-scale investigation of IME. We show that IME is a near-ubiquitous feature among a majority (91%) of coral reef ecosystems surveyed, creating near-island âhotspots' of phytoplankton biomass throughout the upper water column. Variations in IME strength are governed by geomorphic type (atoll vs island), bathymetric slope, reef area and local human impacts (for example, human-derived nutrient input). These ocean oases increase nearshore phytoplankton biomass by up to 86% over oceanic conditions, providing basal energetic resources to higher trophic levels that support subsistence-based human populations
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