Increased Attention and Memory for Beloved-Related Information During Infatuation: Behavioral and Electrophysiological Data

Emotionally salient information is well attended and remembered. It has been shown that infatuated individuals have increased attention for their beloved. It is unknown whether this attention bias generalizes to information related to the beloved. Moreover, infatuated individuals report to remember trivial things about their beloved, but this has not yet been tested empirically. In two studies, we tested whether infatuated individuals have increased attention and memory for beloved-related information. In a passive viewing task (Study 1), the late positive potential, an event-related potential (ERP) component reflecting motivated attention, was enhanced for beloved-related vs friend-related words/phrases. In a recognition task (Study 2), memory performance and the frontal and parietal ERP old/new effects, reflecting familiarity and recollection, respectively, were not enhanced for beloved-related compared with friend-related words/phrases. In free recall tasks in both studies, memory was better for beloved-related than friend-related words/phrases. This research reveals that attention and memory are enhanced for beloved-related information. These attention and memory biases for beloved-related information were not due to valence, semantic relatedness, or experience, but to arousal. To conclude, romantic love has profound effects on cognition that play a clear role in daily life

The effects of anxiety and situation-specific context on perceptual–motor skill: a multi-level investigation

We examined the effects of anxiety and situation- specific contextual information on attentional, interpretational, and behavioural processes underpinning perceptual– motor performance as proposed by Nieuwenhuys and Oudejans (2012) using an in situ task. Twelve skilled cricket batsmen played against a skilled spin bowler under conditions manipulated to induce low and high levels of anxiety and the presence of low and high levels of situation-specific context. High anxiety decreased the number of good bat– ball contacts, while high levels of situation-specific context increased the number of times the ball was missed. When under high anxiety, participants employed significantly more fixations of shorter duration to more locations, but the effects of anxiety were restricted to the attentional level only. Situation-specific context affected performance and behavioural measures but not anxiety, cognitive load or perceptual–cognitive processes, suggesting that performance is influenced through different mechanisms from anxiety that are independent of working memory load

3D ultrasound reconstruction of sonographic callus:a novel imaging modality for early evaluation of fracture healing

AIMS: The aim of this study was to establish a reliable method for producing 3D reconstruction of sonographic callus. METHODS: A cohort of ten closed tibial shaft fractures managed with intramedullary nailing underwent ultrasound scanning at two, six, and 12 weeks post-surgery. Ultrasound capture was performed using infrared tracking technology to map each image to a 3D lattice. Using echo intensity, semi-automated mapping was performed to produce an anatomical 3D representation of the fracture site. Two reviewers independently performed 3D reconstructions and kappa coefficient was used to determine agreement. A further validation study was undertaken with ten reviewers to estimate the clinical application of this imaging technique using the intraclass correlation coefficient (ICC). RESULTS: Nine of the ten patients achieved union at six months. At six weeks, seven patients had bridging callus of ≥ one cortex on the 3D reconstruction and when present all achieved union. Compared to six-week radiographs, no bridging callus was present in any patient. Of the three patients lacking sonographic bridging callus, one went onto a nonunion (77.8% sensitive and 100% specific to predict union). At 12 weeks, nine patients had bridging callus at ≥ one cortex on 3D reconstruction (100%-sensitive and 100%-specific to predict union). Presence of sonographic bridging callus on 3D reconstruction demonstrated excellent reviewer agreement on ICC at 0.87 (95% confidence interval 0.74 to 0.96). CONCLUSION: 3D fracture reconstruction can be created using multiple ultrasound images in order to evaluate the presence of bridging callus. This imaging modality has the potential to enhance the usability and accuracy of identification of early fracture healing. Cite this article: Bone Joint Res 2021;10(12):759–766

Examining the importance of local and global patterns for familiarity detection in soccer action sequences

Pattern recognition is a defining characteristic of expertise across multiple domains. Given the dynamic interactions at local and global levels, team sports can provide a vehicle for investigating skilled pattern recognition. The aims of this study were to investigate whether global patterns could be recognised on the basis of localised relational information and if relations between certain display features were more important than others for successful pattern recognition. Elite (n = 20), skilled (n = 34), and less-skilled (n = 37) soccer players completed three recognition paradigms of stimuli presented in point-light-stimuli format across three counterbalanced conditions: ‘whole-part’; ‘part-whole’; and ‘whole-whole’. ‘Whole’ clips represented a 11v11 soccer match and ‘part’ clips presented the same passages of play with only two centre forwards or two peripheral players. Elite players recognised significantly more accurately than the skilled and less-skilled groups. Participants were significantly more accurate in the ‘whole-whole’ condition compared to others, and recognised stimuli featuring the two central attacking players significantly more accurately than those featuring peripheral players. Findings provide evidence that elite players can encode localised relations and then extrapolate this information to recognise more global macro patterns

Examining the importance of local and global patterns for familiarity detection in soccer action sequences

Pattern recognition is a defining characteristic of expertise across multiple domains. Given the dynamic interactions at local and global levels, team sports can provide a vehicle for investigating skilled pattern recognition. The aims of this study were to investigate whether global patterns could be recognised on the basis of localised relational information and if relations between certain display features were more important than others for successful pattern recognition. Elite (n = 20), skilled (n = 34), and less-skilled (n = 37) soccer players completed three recognition paradigms of stimuli presented in point-light-stimuli format across three counterbalanced conditions: ‘whole-part’; ‘part-whole’; and ‘whole-whole’. ‘Whole’ clips represented a 11v11 soccer match and ‘part’ clips presented the same passages of play with only two centre forwards or two peripheral players. Elite players recognised significantly more accurately than the skilled and less-skilled groups. Participants were significantly more accurate in the ‘whole-whole’ condition compared to others, and recognised stimuli featuring the two central attacking players significantly more accurately than those featuring peripheral players. Findings provide evidence that elite players can encode localised relations and then extrapolate this information to recognise more global macro patterns

Assessing the impact of drinking water and sanitation on diarrhoeal disease in low- and middle-income settings: Systematic review and meta-regression

Objective: To assess the impact of inadequate water and sanitation on diarrhoeal disease in low- and middle-income settings. Methods: The search strategy used Cochrane Library, MEDLINE & PubMed, Global Health, Embase and BIOSIS supplemented by screening of reference lists from previously published systematic reviews, to identify studies reporting on interventions examining the effect of drinking water and sanitation improvements in low- and middle-income settings published between 1970 and May 2013. Studies including randomised controlled trials, quasi-randomised trials with control group, observational studies using matching techniques and observational studies with a control group where the intervention was well defined were eligible. Risk of bias was assessed using a modified Ottawa-Newcastle scale. Study results were combined using meta-analysis and meta-regression to derive overall and intervention-specific risk estimates. Results: Of 6819 records identified for drinking water, 61 studies met the inclusion criteria, and of 12 515 records identified for sanitation, 11 studies were included. Overall, improvements in drinking water and sanitation were associated with decreased risks of diarrhoea. Specific improvements, such as the use of water filters, provision of high-quality piped water and sewer connections, were associated with greater reductions in diarrhoea compared with other interventions. Conclusions: The results show that inadequate water and sanitation are associated with considerable risks of diarrhoeal disease and that there are notable differences in illness reduction according to the type of improved water and sanitation implemented

Pattern recognition in soccer: perceptions of skilled players and experienced coaches

The ability to perceive and recognise patterns of play is important for skilled performance in sporting environments with strict spatiotemporal constraints. An extensive body of laboratory-based experimental research has examined pattern recognition, yet there has been a lack of qualitative investigations into pattern recognition underpinning skilled performance. We interviewed six skilled soccer defenders and seven experienced coaches to investigate the perceived importance of pattern recognition to ‘game reading’ in soccer and its development in practice. A two-stage reflexive thematic analysis identified seven higher-order and twenty-two lower-order themes relating to the contribution of pattern recognition to game reading in competition and practice. Participants reported that danger and distances, visual perception, anticipation, experience, opposition team, organisation and communication, and development in practice were deemed fundamental to performance in competition. Participants explained that developing pattern recognition skills in representative practice environments supported transfer of these skills into competition. Defenders and coaches emphasised the importance of distance between player and ball, as well as identifying ‘triggers’ which appear linked to a defender’s experience, positional awareness, and organisational skills. Providing defenders with representative scenarios during practice is recommended to stimulate problem-solving and promote familiarity with an opposition team’s patterns of play to support skilled performance

Antiplasmodial and trypanocidal activity of violacein and deoxyviolacein produced from synthetic operons.

BACKGROUND: Violacein is a deep violet compound that is produced by a number of bacterial species. It is synthesized from tryptophan by a pathway that involves the sequential action of 5 different enzymes (encoded by genes vioA to vioE). Violacein has antibacterial, antiparasitic, and antiviral activities, and also has the potential of inducing apoptosis in certain cancer cells. RESULTS: Here, we describe the construction of a series of plasmids harboring the complete or partial violacein biosynthesis operon and their use to enable production of violacein and deoxyviolacein in E.coli. We performed in vitro assays to determine the biological activity of these compounds against Plasmodium, Trypanosoma, and mammalian cells. We found that, while deoxyviolacein has a lower activity against parasites than violacein, its toxicity to mammalian cells is insignificant compared to that of violacein. CONCLUSIONS: We constructed E. coli strains capable of producing biologically active violacein and related compounds, and propose that deoxyviolacein might be a useful starting compound for the development of antiparasite drugs