463 research outputs found

    Extrapolation Theory and the Pricing of REIT Stocks

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    This paper is the winner of the best paper on Real Estate Investment Trusts award (sponsored by the National Association of Real Estate Investment Trusts (NAREIT)] presented at the 2005 American Real Estate Society Annual Meeting. This study evaluates the investment prospects of value stocks in the real estate investment trust (REIT) market. Value stocks are defined as those that carry low prices relative to their earnings, dividends, book assets, or other measures of fundamental value. The empirical results show that from 1990 onwards, value REITs provide superior returns without exposing investors to higher risks. The evidence is consistent with the extrapolation theory, which attributes the mispricing to investors over extrapolating past corporate results into the future. Interestingly, the findings reveal that such extrapolation is asymmetric in the REIT market. While value REITs are underpriced in accordance with the extrapolation theory, no evidence is found that growth REITs are overpriced. The value anomaly also exhibited several temporal traits. Firstly, the value premium varies over time. Secondly, the magnitude of the premium is inversely associated with the market performance. Finally, the value anomaly is not evident in the pricing of REITs in the 1980s.

    Biophysical Analysis of Nucleic Acids

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    This overview unit provides a thorough overview of biophysical methods used for structure analysis, including X‐ray diffraction, nuclear magnetic resonance, optical spectroscopy, theoretical and computational methods, and single‐molecule methods. Advantages and disadvantages of the methods are compared.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/143731/1/cpnc0701.pd

    NMR Determination of Oligonucleotide Structure

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    This unit provides an overview of the use of NMR to determine oligonucleotide structure. It covers basic NMR spectral properties, acquisition of interproton distance restraints and torsion angle restraints, structure refinement, assessment of the quality of the structure obtained. Software programs used in the process are also described.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/143742/1/cpnc0702.pd

    Antiphospholipid Antibody Syndrome In The Thrombophilia Pilot Project

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/106074/1/jth01382.pd

    Cassini VIMS observations of H3+ emission on the nightside of Jupiter

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    We present the first detailed analysis of H3+ nightside emission from Jupiter, using Visual and Infrared Mapping Spectrometer (VIMS) data from the Cassini flyby in 2000–2001, producing the first Jovian maps of nightside H3+ emission, temperature, and column density. Using these, we identify and characterize regions of H3+ nightside emission, compared against past observations of H3+ emission on the dayside. We focus our investigation on the region previously described as “mid-to-low latitude emission,” the source for which has been controversial. We find that the brightest of this emission is generated at Jovigraphic latitudes similar to the most equatorward extent of the main auroral emission but concentrated at longitudes eastward of this emission. The emission is produced by enhanced H3+ density, with temperatures dropping away in this region. This emission has a loose association with the predicted location of diffuse aurora produced by pitch angle scattering in the north, but not in the south. This emission also lays in the path of subrotating winds flowing from the aurora, suggesting a transport origin. Some differences are seen between dayside and nightside subauroral emissions, with dayside emission extending more equatorward, perhaps caused by the lack of sunlight ionization on the nightside, and unmeasured changes in temperature. Ionospheric temperatures are hotter in the polar region (~1100–1500 K), dropping away toward the equator (as low as 750 K), broadly similar to values on the dayside, highlighting the dominance of auroral effects in the polar region. No equatorial emission is observed, suggesting that very little particle precipitation occurs away from the polar regions

    Improving sleep quality leads to better mental health: A meta-analysis of randomised controlled trials.

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    The extent to which sleep is causally related to mental health is unclear. One way to test the causal link is to evaluate the extent to which interventions that improve sleep quality also improve mental health. We conducted a meta-analysis of randomised controlled trials that reported the effects of an intervention that improved sleep on composite mental health, as well as on seven specific mental health difficulties. 65 trials comprising 72 interventions and N = 8608 participants were included. Improving sleep led to a significant medium-sized effect on composite mental health (g+ = −0.53), depression (g+ = −0.63), anxiety (g+ = −0.51), and rumination (g+ = −0.49), as well as significant small-to-medium sized effects on stress (g+ = −0.42), and finally small significant effects on positive psychosis symptoms (g+ = −0.26). We also found a dose response relationship, in that greater improvements in sleep quality led to greater improvements in mental health. Our findings suggest that sleep is causally related to the experience of mental health difficulties. Future research might consider how interventions that improve sleep could be incorporated into mental health services, as well as the mechanisms of action that explain how sleep exerts an effect on mental health

    Modeling DNA Structure, Elasticity and Deformations at the Base-pair Level

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    We present a generic model for DNA at the base-pair level. We use a variant of the Gay-Berne potential to represent the stacking energy between neighboring base-pairs. The sugar-phosphate backbones are taken into account by semi-rigid harmonic springs with a non-zero spring length. The competition of these two interactions and the introduction of a simple geometrical constraint leads to a stacked right-handed B-DNA-like conformation. The mapping of the presented model to the Marko-Siggia and the Stack-of-Plates model enables us to optimize the free model parameters so as to reproduce the experimentally known observables such as persistence lengths, mean and mean squared base-pair step parameters. For the optimized model parameters we measured the critical force where the transition from B- to S-DNA occurs to be approximately 140pN140{pN}. We observe an overstretched S-DNA conformation with highly inclined bases that partially preserves the stacking of successive base-pairs.Comment: 15 pages, 25 figures. submitted to PR
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