Sharing the Burden of Collective Security in the European Union. Research Note

This article compares European Union (EU) burden-sharing in security governance distinguishing between assurance, prevention, protection, and compellence policies. We employ joint-product models and examine the variation in the level of publicness, the asymmetry of the distribution of costs and benefits, and aggregation technologies in each policy domain. Joint-product models predict equal burden sharing for protection and assurance because of their respective weakest-link and summation aggregation technologies with symmetric costs. Prevention is also characterized by the technology of summation, but asymmetry of costs implies uneven burden-sharing. Uneven burden-sharing is predicted for compellence because it has the largest asymmetry of costs and a best-shot aggregation technology. Evaluating burden-sharing relative to a country?s ability to contribute, Kendall tau-tests examine the rank-correlation between security burden and the capacity of EU member states. These tests show that the smaller EU members disproportionately shoulder the costs of assurance and protection; wealthier EU members carry a somewhat disproportionate burden in the provision of prevention, and larger EU members in the provision of compellence. When analyzing contributions relative to expected benefits, asymmetric marginal costs can largely explain uneven burden-sharing. The main conclusion is that the aggregated burden of collective security governance in the EU is shared quite evenly

Continuity and change in initial police training: A longitudinal case study.

This thesis, the fieldwork for which was undertaken between 2010 and 2012, examined an initial police training programme in one police force, ‘Ashton Police’ and of one cohort of 20 student officers, over a two year period. I conducted interviews with student officers and training staff, observations of classroom and operational training and documentary analysis to produce a longitudinal case study of initial police training and early career socialisation. Whilst this was a small-scale research project, its findings are applicable to initial training and policing more broadly as well as to current reforms. I found that many of the cohort of student officers in my study already had policing experience, some in Ashton Police itself. This meant that pre-existing features of police culture served to partially undermine some of the formal intentions of the programme, from the outset. Furthermore, I found that the different types of training were all problematic. Formal, classroom based training was insufficiently connected with operational police work. Supervised field training was overly reliant on the allocation of a single field trainer for the duration of that period and was adversely affected by organisational change. Informal training (as members of operational reliefs) became so attenuated from the training process, it resembled far more a period of work rather than of training. For these reasons student officers often appeared inadequately prepared for police work. I conclude that despite the introduction of a new programme (the Initial Police Learning and Development Programme) in 2006 in Ashton Police, intended to allow innovation in the way in which initial training was delivered, considerable continuity existed alongside change. This was particularly noticeable in the long-standing conflict between, on the one hand, legalistic and procedural approaches to initial training and on the other, a more humanistic approach. It appeared at times that the purpose of initial training was not clear. In relation to the wider arena of initial police training, I argue that many of its problems originate in the historical and socioeconomic context. The reforms of initial training and the new programme, from 2006, took place in politically contentious times for the police and so, carried too great an expectation of their impact. Some aspects of reform were possibly necessary to make but were not sufficient for long-term change. I argue that a social democratic perspective of the police that focuses on the detrimental impact on the police of social conditions in ‘liberal’ (rather than ‘social’) democracies provides a fuller understanding of the limits of these and future initial training reforms

NATO and the Ukraine Crisis: Collective Securitisation

AbstractIn securitisation theory (ST) little attention has been paid to how actors undertake securitisation collectively. The empirical focus of that theory has also, paradoxically, neglected the military-strategic sector and with it regional security organisations like NATO. Such an oversight is worth correcting for three reasons. First, NATO is constantly engaged in securitisation across a range of issues, a process that reflects an underappreciated recursive interaction between the Alliance and its member states. Second, the Ukraine crisis has resulted in Russia being explicitly identified as a source of threat and so has triggered a successful collective (re)securitisation by the Alliance. Third, a framework that demonstrates NATO’s standing as a securitising actor has potential relevance to other regional security organisations. This article discusses and amends ST in service of an approach that permits securitisation by actors other than the state, in this case NATO. A model of collective securitisation is presented and then applied empirically to the post-Cold War desecuritisation of Russia and its subsequent resecuritisation following the annexation of Crimea. The implications of resecuritisation for the emergence of a self-reinforcing security dilemma in NATO-Russia relations are also considered.</jats:p

A Novel Implantable Glaucoma Valve Using Ferrofluid

Purpose To present a novel design of an implantable glaucoma valve based on ferrofluidic nanoparticles and to compare it with a well-established FDA approved valve. Setting: Massachusetts Eye & Ear Infirmary, Boston, USA. Methods: A glaucoma valve was designed using soft lithography techniques utilizing a water-immiscible magnetic fluid (ferrofluid) as a pressure-sensitive barrier to aqueous flow. Two rare earth micro magnets were used to calibrate the opening and closing pressure. In-vitro flow measurements were performed to characterize the valve and to compare it to Ahmed™ glaucoma valve. The reliability and predictability of the new valve was verified by pressure/flow measurements over a period of three months and X-ray diffraction (XRD) analysis over a period of eight weeks. In vivo assessment was performed in three rabbits. Results: In the in vitro experiments, the opening and closing pressures of the valve were 10 and 7 mmHg, respectively. The measured flow/pressure response was linearly proportional and reproducible over a period of three months (1.8 µl/min at 12 mmHg; 4.3 µl/min at 16 mmHg; 7.6 µl/min at 21 mmHg). X-ray diffraction analysis did not show oxidization of the ferrofluid when exposed to water or air. Preliminary in vivo results suggest that the valve is biocompatible and can control the intraocular pressure in rabbits. Conclusions: The proposed valve utilizes ferrofluid as passive, tunable constriction element to provide highly predictable opening and closing pressures while maintaining ocular tone. The ferrofluid maintained its magnetic properties in the aqueous environment and provided linear flow to pressure response. Our in-vitro tests showed reliable and reproducible results over a study period of three months. Preliminary in-vivo results were very promising and currently more thorough investigation of this device is underway

Relationship Between Intraseasonal Oscillation and Subtropical Wind Maxima Over the South Pacific Ocean

The significance of tropical heat sources on higher latitude jet streams has been examined by numerous investigators. Hurrell and Vincent (1990) provide a summary of many of these investigations in their observational case study of the relationship between tropical heating and subtropical wind maxima in the Southern Hemisphere during SOP-1, FGGE. They showed that the divergent outflow from tropical heating associated with the South Pacific Convergence Zone (SPCZ), acted on by the coriolis force, was an important factor in maintaining the subtropical jet on the poleward side of the SPCZ during the period, 6-20 January 1979. They found a similar, but weaker relationship, over the southern Indian Ocean from 3-17 February 1979, a period when the SPCZ heating was greatly reduced and the jet was essentially non-existent. Since their findings were based on a case study and involved the use of the highly-specialized FGGE data set, the natural questions which arose were: (1) Is this relationship a regular feature of the circulation over the South Pacific? and, (2) If so, can it be detected with a routine data set? Another question posed by Hurrell and Vincent in their papers was:(3) How important was the intraseasonal oscillation in causing the enhanced heating and divergent outflow in the Pacific Ocean in January and southern Indian Ocean in February? The purpose of the present paper is to address the answer to these three questions. To accomplish this, some circulation features for an entire warm season in the Southern Hemisphere were examined. The year selected was 1984-85, and the warm season consisted of the 6-month period, 1 November 1984 - 30 April 1985. This period was chosen because there were numerous cases of the westerly wind maxima over the South Pacific and the intraseasonal oscillation was well documented

Temporal lobe epilepsy and surgery selectively alter the dorsal, not the ventral, default-mode network.

The default-mode network (DMN) is a major resting-state network. It can be divided in two distinct networks: one is composed of dorsal and anterior regions [referred to as the dorsal DMN (dDMN)], while the other involves the more posterior regions [referred to as the ventral DMN (vDMN)]. To date, no studies have investigated the potentially distinct impact of temporal lobe epilepsy (TLE) on these networks. In this context, we explored the effect of TLE and anterior temporal lobectomy (ATL) on the dDMN and vDMN. We utilized two resting-state fMRI sessions from left, right TLE patients (pre-/post-surgery) and normal controls (sessions 1/2). Using independent component analysis, we identified the two networks. We then evaluated for differences in spatial extent for each network between the groups, and across the scanning sessions. The results revealed that, pre-surgery, the dDMN showed larger differences between the three groups than the vDMN, and more particularly between right and left TLE than between the TLE patients and controls. In terms of change post-surgery, in both TLE groups, the dDMN also demonstrated larger changes than the vDMN. For the vDMN, the only changes involved the resected temporal lobe for each ATL group. For the dDMN, the left ATL group showed post-surgical increases in several regions outside the ictal temporal lobe. In contrast, the right ATL group displayed a large reduction in the frontal cortex. The results highlight that the two DMNs are not impacted by TLE and ATL in an equivalent fashion. Importantly, the dDMN was the more affected, with right ATL having a more deleterious effects than left ATL. We are the first to highlight that the dDMN more strongly bears the negative impact of TLE than the vDMN, suggesting there is an interaction between the side of pathology and DM sub-network activity. Our findings have implications for understanding the impact TLE and subsequent ATL on the functions implemented by the distinct DMNs

Spatial Genetic Structure of a Symbiotic Beetle-Fungal System: Toward Multi-Taxa Integrated Landscape Genetics

Spatial patterns of genetic variation in interacting species can identify shared features that are important to gene flow and can elucidate co-evolutionary relationships. We assessed concordance in spatial genetic variation between the mountain pine beetle (Dendroctonus ponderosae) and one of its fungal symbionts, Grosmanniaclavigera, in western Canada using neutral genetic markers. We examined how spatial heterogeneity affects genetic variation within beetles and fungi and developed a novel integrated landscape genetics approach to assess reciprocal genetic influences between species using constrained ordination. We also compared landscape genetic models built using Euclidean distances based on allele frequencies to traditional pair-wise Fst. Both beetles and fungi exhibited moderate levels of genetic structure over the total study area, low levels of structure in the south, and more pronounced fungal structure in the north. Beetle genetic variation was associated with geographic location while that of the fungus was not. Pinevolume and climate explained beetle genetic variation in the northern region of recent outbreak expansion. Reciprocal genetic relationships were only detectedin the south where there has been alonger history of beetle infestations. The Euclidean distance and Fst-based analyses resulted in similar models in the north and over the entire study area, but differences between methods in the south suggest that genetic distances measures should be selected based on ecological and evolutionary contexts. The integrated landscape genetics framework we present is powerful, general, and can be applied to other systems to quantify the biotic and abiotic determinants of spatial genetic variation within and among taxa

Theta and high-frequency activity mark spontaneous recall of episodic memories.

Humans possess the remarkable ability to search their memory, allowing specific past episodes to be re-experienced spontaneously. Here, we administered a free recall test to 114 neurosurgical patients and used intracranial theta and high-frequency activity (HFA) to identify the spatiotemporal pattern of neural activity underlying spontaneous episodic retrieval. We found that retrieval evolved in three electrophysiological stages composed of: (1) early theta oscillations in the right temporal cortex, (2) increased HFA in the left hemisphere including the medial temporal lobe (MTL), left inferior frontal gyrus, as well as the ventrolateral temporal cortex, and (3) motor/language activation during vocalization of the retrieved item. Of these responses, increased HFA in the left MTL predicted recall performance. These results suggest that spontaneous recall of verbal episodic memories involves a spatiotemporal pattern of spectral changes across the brain; however, high-frequency activity in the left MTL represents a final common pathway of episodic retrieval

CCR5AS lncRNA variation differentially regulates CCR5, influencing HIV disease outcome.

Multiple genome-wide studies have identified associations between outcome of human immunodeficiency virus (HIV) infection and polymorphisms in and around the gene encoding the HIV co-receptor CCR5, but the functional basis for the strongest of these associations, rs1015164A/G, is unknown. We found that rs1015164 marks variation in an activating transcription factor 1 binding site that controls expression of the antisense long noncoding RNA (lncRNA) CCR5AS. Knockdown or enhancement of CCR5AS expression resulted in a corresponding change in CCR5 expression on CD4+ T cells. CCR5AS interfered with interactions between the RNA-binding protein Raly and the CCR5 3' untranslated region, protecting CCR5 messenger RNA from Raly-mediated degradation. Reduction in CCR5 expression through inhibition of CCR5AS diminished infection of CD4+ T cells with CCR5-tropic HIV in vitro. These data represent a rare determination of the functional importance of a genome-wide disease association where expression of a lncRNA affects HIV infection and disease progression