Combined electronic nose and tongue for a flavour sensing system

We present a novel, smart sensing system developed for the flavour analysis of liquids. The system comprises both a so-called "electronic tongue" based on shear horizontal surface acoustic wave (SH-SAW) sensors analysing the liquid phase and a so-called "electronic nose" based on chemFET sensors analysing the gaseous phase. Flavour is generally understood to be the overall experience from the combination of oral and nasal stimulation and is principally derived from a combination of the human senses of taste (gustation) and smell (olfaction). Thus, by combining two types of microsensors, an artificial flavour sensing system has been developed. Initial tests conducted with different liquid samples, i.e. water, orange juice and milk (of different fat content), resulted in 100% discrimination using principal components analysis; although it was found that there was little contribution from the electronic nose. Therefore further flavour experiments were designed to demonstrate the potential of the combined electronic nose/tongue flavour system. Consequently, experiments were conducted on low vapour pressure taste-biased solutions and high vapour pressure, smell-biased solutions. Only the combined flavour analysis system could achieve 100% discrimination between all the different liquids. We believe that this is the first report of a SAW-based analysis system that determines flavour through the combination of both liquid and headspace analysis

Assessing the Early Impact of School of One: Evidence from Three School-Wide Pilots

For more than 150 years, education has been organized around classrooms in which one teacher attempts to meet the needs of a large group of students who have a wide range of prior experiences, knowledge, and ways of learning. This structure makes it exceedingly difficult to ensure that all students meet the same standards of performance. School of One (SO1) is an innovative, technology-enhanced math program that seeks to "meet students where they are," by creating individual learning plans, offering multiple teaching strategies, and using daily assessments to monitor progress and adapt lessons as needed. This report evaluates SO1's impact on students' state test scores during the first year of school-wide implementation in three New York City middle schools. It also presents exploratory analysis examining whether exposure to more SO1 material, or mastery of SO1 skills, is associated with improved math performance. Given the early stage of the program's development, the authors caution that the evaluation should not be interpreted as a definitive assessment of SO1's effectiveness. Rather, the findings provide a preliminary assessment of SO1's initial impact on students' math achievement and offer insights that may contribute to the program's development and inform future research

Koinonia

In This IssueVocation and an Integrated Christian Worldview: Reprint from Love Your God with All Your Mind: The Role of Reason in the Life of the Soul by J.P. Moreland SWOT, MBO, and Other Life Perils, James Kanning Contemporary Christian Music Challenges Activity Directors to Assess Campus Spiritual Climate, Melissa J. Schermer In The FieldAnticipatory Consciousness: A Learning Paradigm for College Students, Eileen Hulme Around CampusUsing Technology in Wellness Programming, Kadi Cole Regular FeaturesPresident\u27s Corner Editor\u27s Disk Annual Conference: Sunny Southern California Welcomes ACSD 1999 News from the Regions: Spotlight on the Lake Region Coalition of Christian College Activities (CoCCA): Hot Ideas Book Review: Virtual Faith: The Irreverent Spiritual Quest of Generation X Perspective: Tales of a First Year RDhttps://pillars.taylor.edu/acsd_koinonia/1030/thumbnail.jp

Aspidoscelis laredoensis and A. gularis hybridization.

13 pages : illustrations (some color) ; 26 cm.Karyotypes and allozyme data for 32 genetic loci overwhelmingly support the conclusion that Aspidoscelis laredoensis is a diploid all-female species that had a hybrid origin between A. gularis x A. sexlineatus. Comparisons of allozymes in individuals representing three mother-to-daughter generations raised in the laboratory suggest that they reproduce by parthenogenetic cloning. In addition to two previously described morphotypes (pattern classes A and B) that occur in southern Texas, we report the existence of three all-female clonal lineages based on allozymes. Individuals of at least one of these lineages occasionally hybridize in nature with males of A. gularis, producing viable and healthy triploid offspring that can grow to adulthood, one of which herself produced an offspring in the laboratory and could have represented a new, clonal triploid species. The possibility exists that cloned offspring of triploid hybrids are present in South Texas and/or northern Mexico, awaiting discovery. These would represent a new species that would appear to be very similar to A. laredoensis

Comparison of data acquisition methods for the identification and quantification of histone post-translational modifications on a Q Exactive HF hybrid quadrupole Orbitrap mass spectrometer.

RATIONALE: Histone PTMs play key roles in regulating eukaryotic gene expression. Mass spectrometry (MS) has emerged as a powerful method to characterize and quantify histone PTMs as it allows unbiased identification and quantification of multiple histone PTMs including combinations of the modifications present. METHODS: In this study we compared a range of data acquisition methods for the identification and quantification of the histone PTMs using a Q Exactive HF Orbitrap. We compared three different data-dependent analysis (DDA) methods with MS2 resolutions of 120K, 60K, 30K. We also compared a range of data-independent analysis (DIA) methods using MS2 isolation windows of 20 m/z and DIAvw to identify and quantify histone PTMs in Chinese Hamster Ovary (CHO) cells. RESULTS: The increased number of MS2 scans afforded by the lower resolution methods resulted in a higher number of queries, peptide sequence matches (PSMs) and a higher number of peptide proteoforms with a Mascot Ion score greater than 46. No difference in the proportion of peptide proteoforms with Delta scores >17 was observed. Comparing the data acquisition methods increased repeatability in terms of lower CVs afforded by DIA MS1 60K MS2 30K 20m/z isolation windows was observed. CONCLUSION: We observed that DIA which offers advantages in flexibility and identification of isobaric peptide proteoforms performs as well as DDA in the analysis of histone PTMs. We were able to identify 71 modified histone peptides for histone H3 and H4 and quantified 64 across each of the different acquisition methods

Winner loses all: The 2015 French regional elections

The French regional elections of 2015 presented two contrasting images of France: in the first round, a political landscape divided into three major blocs with the far-right Front National (FN) the dominant force; in the second round, a landscape as bipolarized between centre-right and centre-left as at any time under the Fifth Republic and with the FN a distant third. This article explores these two representations of political France and analyses the elections in relation to the wider French political context. It discusses the electoral dynamics that enabled the traditional parties to preserve their duopoly of regional power despite the increasingly intrusive challenge to their hegemony mounted by an ever more electorally potent FN

Linkage Between SecA Dimerization and Ligand Binding

Abstract. Introduction and Objectives:. There have, yet, been only few attempts to phonetically characterize the vocalizations of pain, although there is wide agreement that moaning, groaning, or other nonverbal utterance can be indicative of pain. We studied the production of vowels “u,” “a,” “i”, and “schwa” (central vowel, sounding like a darker “e” as in hesitations like “ehm”)—as experimental approximations to natural vocalizations. Methods:. In 50 students vowel production and self-report ratings were assessed during painful and nonpainful heat stimulation (hot water immersion) as well as during baseline (no-stimulation). The phonetic parameters extracted were pitch (mean F0), phonatory fluctuations (range F0) and loudness (acoustic energy level). Results:. Only for the vowels “u” and “schwa,” which might be considered best approximations to moaning and groaning, did pitch and loudness increase during pain. Furthermore, changes from nonpainful to painful stimulations in these parameters also significantly predicted concurrent changes in pain ratings. Conclusion:. Vocalization characteristics of pain seem to be best described by an increase in pitch and in loudness. Future studies using more specific and comprehensive phonetic analyses will surely help to provide an even more precise characterization of vocalizations because of pain