107 research outputs found

    Observational validation of the diffusive convection flux laws in the Amundsen Basin, Arctic Ocean

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    The low levels of mechanically driven mixing in many regions of the Arctic Ocean make double diffusive convection virtually the only mechanism for moving heat up from the core of Atlantic Water towards the surface. In an attempt to quantify double diffusive heat fluxes in the Arctic Ocean, a temperature microstructure experiment was performed as a part of the North Pole Environmental Observatory (NPEO) 2013 field season from the drifting ice station Barneo located in the Amundsen Basin near the Lomonosov Ridge (89.58N, 758W). A diffusive convective thermohaline staircase was present between 150 and 250 m in nearly all of the profiles. Typical vertical heat fluxes across the high-gradient interfaces were consistently small, O(1021 )Wm22 . Our experiment was designed to resolve the staircase and differed from earlier Arctic studies that utilized inadequate instrumentation or sampling. Our measured fluxes from temperature microstructure agree well with the laboratory derived flux laws compared to previous studies, which could find agreement only to within a factor of two to four. Correlations between measured and parameterized heat fluxes are slightly higher when using the more recent Flanagan et al. [2013] laboratory derivation than the more commonly used derivation presented in Kelley [1990]. Nusselt versus Rayleigh number scaling reveals the convective exponent, g, to be closer to 0.29 as predicted by recent numerical simulations of single-component convection rather than the canonical 1/3 assumed for double diffusion. However, the exponent appears to be sensitive to how convective layer height is defined.publishedVersio

    Diffusive vertical heat flux in the Canada Basin of the Arctic Ocean inferred from moored instruments

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    Author Posting. © American Geophysical Union, 2014. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Journal of Geophysical Research: Oceans 119 (2014): 496-508, doi:10.1002/2013JC009346.Observational studies have shown that an unprecedented warm anomaly has recently affected the temperature of the Atlantic Water (AW) layer lying at intermediate depth in the Arctic Ocean. Using observations from four profiling moorings, deployed in the interior of the Canada Basin between 2003 and 2011, the upward diffusive vertical heat flux from this layer is quantified. Vertical diffusivity is first estimated from a fine-scale parameterization method based on CTD and velocity profiles. Resulting diffusive vertical heat fluxes from the AW are in the range 0.1–0.2 W m−2 on average. Although large over the period considered, the variations of the AW temperature maximum yields small variations for the temperature gradient and thus the vertical diffusive heat flux. In most areas, variations in upward diffusive vertical heat flux from the AW have only a limited effect on temperature variations of the overlying layer. However, the presence of eddies might be an effective mechanism to enhance vertical heat transfer, although the small number of eddies sampled by the moorings suggest that this mechanism remains limited and intermittent in space and time. Finally, our results suggest that computing diffusive vertical heat flux with a constant vertical diffusivity of ∼2 × 10−6 m2 s−1 provides a reasonable estimate of the upward diffusive heat transfer from the AW layer, although this approximation breaks down in the presence of eddies.C. Lique acknowledge support from JISAO and the Program on Climate Change of the University of Washington. J. Guthrie and J. Morison are supported by National Science Foundation grants ARC-0909408 and ARC-0856330. M. Steele is supported by the Office of Naval Researches Arctic and Global Prediction Program, by NSFs Division of Polar Programs, and by NASAs Cryosphere and Physical Oceanography programs. Support for the BGOS program and R. Krishfield was provided by the National Science Foundation (under grants ARC-0806115, ARC-0631951, ARC-0806306, and ARC-0856531) and Woods Hole Oceanographic Institution internal funding. For A. Proshutinsky, this research is supported by the National Science Foundation Office of Polar Programs, awards ARC-1203720 and ARC-0856531.2014-07-2

    Voice and Agency: Empowering women and girls for shared prosperity

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    This document presents Voice and Agency: Empowering women and girls for shared prosperity is a major new report by the World Bank that shines a spotlight on the value of voice and agency, the patterns of constraints that limit their realization, and the associated costs, not only to individual women but to their families, communities, and societies. It highlights promising policies and interventions, and it identifies priority areas where further research and more and better data and evidence are needed. Underlining that agency has both intrinsic and instrumental, concrete value, this report puts advancing women's voice and agency squarely on the international development agenda

    Snowpack measurements suggest role for multi-year sea ice regions in Arctic atmospheric bromine and chlorine chemistry

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    As sources of reactive halogens, snowpacks in sea ice regions control the oxidative capacity of the Arctic atmosphere. However, measurements of snowpack halide concentrations remain sparse, particularly in the high Arctic, limiting our understanding of and ability to parameterize snowpack participation in tropospheric halogen chemistry. To address this gap, we measured concentrations of chloride, bromide, and sodium in snow samples collected during polar spring above remote multi-year sea ice (MYI) and first-year sea ice (FYI) north of Greenland and Alaska, as well as in the central Arctic, and compared these measurements to a larger dataset collected in the Alaskan coastal Arctic by Krnavek et al. (2012). Regardless of sea ice region, these surface snow samples generally featured lower salinities, compared to coastal snow. Surface snow in FYI regions was typically enriched in bromide and chloride compared to seawater, indicating snowpack deposition of bromine and chlorine-containing trace gases and an ability of the snowpack to participate further in bromine and chlorine activation processes. In contrast, surface snow in MYI regions was more often depleted in bromide, indicating it served as a source of bromine-containing trace gases to the atmosphere prior to sampling. Measurements at various snow depths indicate that the deposition of sea salt aerosols and halogen-containing trace gases to the snowpack surface played a larger role in determining surface snow halide concentrations compared to upward brine migration from sea ice. Calculated enrichment factors for bromide and chloride, relative to sodium, in the MYI snow samples suggests that MYI regions, in addition to FYI regions, have the potential to play an active role in Arctic boundary layer bromine and chlorine chemistry. The ability of MYI regions to participate in springtime atmospheric halogen chemistry should be considered in regional modeling of halogen activation and interpretation of satellite-based tropospheric bromine monoxide column measurements

    Role of Condom Negotiation on Condom use among Women of Reproductive Age in three Districts in Tanzania.

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    ABSTRACT: BACKGROUND: HIV/AIDS remains being a disease of great public health concern worldwide. In regions such as sub-Saharan Africa (SSA) where women are disproportionately infected with HIV, women are reportedly less likely capable of negotiating condom use. However, while knowledge of condom use for HIV prevention is extensive among men and women in many countries including Tanzania, evidence is limited about the role of condom negotiation on condom use among women in rural Tanzania. METHODS: Data originate from a cross-sectional survey of random households conducted in 2011 in Rufiji, Kilombero and Ulanga districts in Tanzania. The survey assessed health-seeking behaviour among women and children using a structured interviewer-administered questionnaire. A total of 2,614 women who were sexually experienced and aged 15--49 years were extracted from the main database for the current analysis. Linkage between condom negotiation and condom use at the last sexual intercourse was assessed using multivariate logistic regression. RESULTS: Prevalence of condom use at the last sexual intercourse was 22.2% overall, ranging from12.2% among married women to 54.9% among unmarried (single) women. Majority of the women (73.4%) reported being confident to negotiate condom use, and these women were significantly more likely than those who were not confident to have used a condom at the last sexual intercourse (OR = 3.13, 95% CI 2.22-4.41). This effect was controlled for marital status, age, education, religion, number of sexual partners, household wealth and knowledge of HIV prevention by condom use. CONCLUSION: Confidence to negotiate condom use is a significant predictor of actual condom use among women in rural Tanzania. Women especially unmarried ones or those in multiple partnerships should be empowered with condom negotiation skills to enhance their sexual and reproductive health outcomes

    SNP Array Karyotyping Allows for the Detection of Uniparental Disomy and Cryptic Chromosomal Abnormalities in MDS/MPD-U and MPD

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    We applied single nucleotide polymorphism arrays (SNP-A) to study karyotypic abnormalities in patients with atypical myeloproliferative syndromes (MPD), including myeloproliferative/myelodysplastic syndrome overlap both positive and negative for the JAK2 V617F mutation and secondary acute myeloid leukemia (AML). In typical MPD cases (N = 8), which served as a control group, those with a homozygous V617F mutation showed clear uniparental disomy (UPD) of 9p using SNP-A. Consistent with possible genomic instability, in 19/30 MDS/MPD-U patients, we found additional lesions not identified by metaphase cytogenetics. In addition to UPD9p, we also have detected UPD affecting other chromosomes, including 1 (2/30), 11 (4/30), 12 (1/30) and 22 (1/30). Transformation to AML was observed in 8/30 patients. In 5 V617F+ patients who progressed to AML, we show that SNP-A can allow for the detection of two modes of transformation: leukemic blasts evolving from either a wild-type jak2 precursor carrying other acquired chromosomal defects, or from a V617F+ mutant progenitor characterized by UPD9p. SNP-A-based detection of cryptic lesions in MDS/MPD-U may help explain the clinical heterogeneity of this disorder

    Genome-Wide Analysis Reveals a Complex Pattern of Genomic Imprinting in Mice

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    Parent-of-origin–dependent gene expression resulting from genomic imprinting plays an important role in modulating complex traits ranging from developmental processes to cognitive abilities and associated disorders. However, while gene-targeting techniques have allowed for the identification of imprinted loci, very little is known about the contribution of imprinting to quantitative variation in complex traits. Most studies, furthermore, assume a simple pattern of imprinting, resulting in either paternal or maternal gene expression; yet, more complex patterns of effects also exist. As a result, the distribution and number of different imprinting patterns across the genome remain largely unexplored. We address these unresolved issues using a genome-wide scan for imprinted quantitative trait loci (iQTL) affecting body weight and growth in mice using a novel three-generation design. We identified ten iQTL that display much more complex and diverse effect patterns than previously assumed, including four loci with effects similar to the callipyge mutation found in sheep. Three loci display a new phenotypic pattern that we refer to as bipolar dominance, where the two heterozygotes are different from each other while the two homozygotes are identical to each other. Our study furthermore detected a paternally expressed iQTL on Chromosome 7 in a region containing a known imprinting cluster with many paternally expressed genes. Surprisingly, the effects of the iQTL were mostly restricted to traits expressed after weaning. Our results imply that the quantitative effects of an imprinted allele at a locus depend both on its parent of origin and the allele it is paired with. Our findings also show that the imprinting pattern of a locus can be variable over ontogenetic time and, in contrast to current views, may often be stronger at later stages in life
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