5,954 research outputs found
Efficacy and safety of the long-term oral administration of carprofen in the treatment of osteoarthritis in dogs
The aim of this study conducted in France was to confirm the efficacy and safety of the oral administration of carprofen (RimadylÂź) at 4 mg/kg once a day during four months in the treatment of clinically chronic osteoarthritis in dogs. One hundred and ten dogs with chronic clinical signs of osteoarthritis were enrolled. The overall severity of the osteoarthritis condition and the clinical signs of osteoarthritis were assessed using visual analogue scales (VAS) on days 0, 5, 30, 60, 90 and 120. During the same visits, owners were asked to perform their own efficacy assessment through the grading of seven parameters using categorical scales. Hematological analyses were performed on days 0 and 120. Clinical blood chemistry evaluations were performed on days 0, 5, 60 and 120. The percentage of dogs showing a positive treatment effect increased from 12% on day 5 to 74% on day 120. The mean VAS scores significantly decreased throughout the study (P â€0.05). Gastrointestinal undesirable effects likely to be related to carprofen but with no harmful consequences were observed in 5% of treated dogs. No detrimental effects of the treatment on haematological, renal and hepatic parameters were observed. These results show that carprofen at 4 mg/kg once daily can be safely used over a 4 month period in the treatment of osteoarthritis in dogs and provides a steadily increasing improvement of the clinical signs
The effect of ambipolar diffusion on low-density molecular ISM filaments
The filamentary structure of the molecular interstellar medium and the
potential link of this morphology to star formation have been brought into
focus recently by high resolution observational surveys. An especially puzzling
matter is that local interstellar filaments appear to have the same thickness,
independent of their column density. This requires a theoretical understanding
of their formation process and the physics that governs their evolution. In
this work we explore a scenario in which filaments are dissipative structures
of the large-scale interstellar turbulence cascade and ion-neutral friction
(also called ambipolar diffusion) is affecting their sizes by preventing
small-scale compressions. We employ high-resolution, 3D MHD simulations,
performed with the grid code RAMSES, to investigate non-ideal MHD turbulence as
a filament formation mechanism. We focus the analysis on the mass and thickness
distributions of the resulting filamentary structures. Simulations of both
driven and decaying MHD turbulence show that the morphologies of the density
and the magnetic field are different when ambipolar diffusion is included in
the models. In particular, the densest structures are broader and more massive
as an effect of ion-neutral friction and the power spectra of both the velocity
and the density steepen at a smaller wavenumber. The comparison between ideal
and non-ideal MHD simulations shows that ambipolar diffusion causes a shift of
the filament thickness distribution towards higher values. However, none of the
distributions exhibit the pronounced peak found in the observed local
filaments. Limitations in dynamical range and the absence of self-gravity in
these numerical experiments do not allow us to conclude at this time whether
this is due to the different filament selection or due to the physics inherent
of the filament formation.Comment: A&A accepte
Lâautonomie des commissions permanentes de lâAssemblĂ©e nationale et la discipline de parti de 1984 Ă 1991
DĂšs le dĂ©but des annĂ©es soixante sâest posĂ©e la question de la revalorisation du rĂŽle du dĂ©putĂ© quĂ©bĂ©cois. Les commissions parlementaires ont Ă©tĂ© considĂ©rĂ©es, dĂšs cette Ă©poque, comme un bon moyen pour augmenter lâinfluence du dĂ©putĂ© et favoriser lâautonomie du pouvoir lĂ©gislatif face au pouvoir exĂ©cutif. Cet article veut prĂ©cisĂ©ment cerner le degrĂ© dâautonomie reconnu aux commissions permanentes depuis la derniĂšre grande rĂ©forme parlementaire Ă lâAssemblĂ©e nationale du QuĂ©bec, en 1984. AprĂšs avoir examinĂ© trois types dâautonomie, on est amenĂ© Ă conclure quâune faible partie du travail des commissions est assumĂ©e dâune maniĂšre autonome, soit essentiellement le travail rĂ©alisĂ© dans le cadre des « mandats dâinitiative » et des mandats de surveillance des organismes publics.In the early sixties, the idea to increase the powers of National Assembly members became an issue in QuĂ©bec. At that time (and still now) parliamentary committees were seen as a good way to extend members' influence and render the legislative power more autonomous in relation to the Executive Council. The aim of this paper is to study the degree of autonomy given to the standing committees since the last extensive parliamentary reform, in 1984. We will consider three levels of autonomy which will lead us to conclude that committee activities are essentially free of the Executive Council's control when committees work on self-appointed mandates or exercise their mandate to supervise public bodies
On Algorithms Based on Joint Estimation of Currents and Contrast in Microwave Tomography
This paper deals with improvements to the contrast source inversion method
which is widely used in microwave tomography. First, the method is reviewed and
weaknesses of both the criterion form and the optimization strategy are
underlined. Then, two new algorithms are proposed. Both of them are based on
the same criterion, similar but more robust than the one used in contrast
source inversion. The first technique keeps the main characteristics of the
contrast source inversion optimization scheme but is based on a better
exploitation of the conjugate gradient algorithm. The second technique is based
on a preconditioned conjugate gradient algorithm and performs simultaneous
updates of sets of unknowns that are normally processed sequentially. Both
techniques are shown to be more efficient than original contrast source
inversion.Comment: 12 pages, 12 figures, 5 table
Contribution à l'étude des culicidés d'Afrique occidentale : description d'Aedes (Aedimorphus) mattinglyi sp. n., Aedes (Banksinella) jamoti sp. n., notes complémentaires sur Aedes (Aedimorphus) stokesi Evans, Aedes(Banksinella) bolensis Edwards
Possibilities of establishing export industries in the Associated African and Malagasy States. Processing of wood and manufacture of articles of wood: First stage of processing; sawing, peeling, rotary cutting, slicing; Second stage of processing: profiles, mouldings, plywood, panels; finished products: for building purposes and furniture. Summary report. VIII/227/(74)-E
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