A Comparison of Women of Color and Non-Hispanic White Women on Factors Related to Leaving a Violent Relationship

This study compares women of color and non-Hispanic White women regarding the influence of socioeconomic status, family investment, and psychological abuse on leaving a violent relationship. It was found that most women who left stayed away for less than a month. Women of color and non-Hispanic White women did not differ in their length or rate of leaving, although women of color left more frequently when they did leave. Factors associated with leaving for both groups were threat with a weapon, psychological abuse, being single, and having fewer adults in the household. Women of color with higher socioeconomic status were less likely to leave, which was not the case for non-Hispanic White women. Non-Hispanic White women were more likely to leave if they had lived with their partners less than 5 years and had children at home.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90886/1/Lacey-Saunders-Zhang 2011-Women of color vs white women - factors in leaving violent relationahip JIV .pd

What Attracts Men Who Batter to Their Partners? An Exploratory Study

Men who batter, because of particular personality traits and sense of entitlement, may select partners whom they perceive will be dependent on them, meet their emotional needs, or be “objects” of physical attractiveness. During treatment intake, 181 offenders responded to the question, “What attracted you to her (your partner)?” We explored whether men who mentioned their own needs or her physical traits would engage in more frequent and severe violence and would have specific forms of personality disorder dimensions or personality traits. Six categories of attraction, including “her physical traits” and “his needs,” were derived from the men’s responses. The results showed that men who focused on their partners’ physical attractiveness were more likely to be violent after treatment. Men who cited their own needs for their attraction had higher scores on borderline personality, alcohol abuse, and psychotic thinking and lower scores on compulsive-conformingPeer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/89970/1/Saunders-Kurko-Barlow-Crane 2011 What Attracts Men Who Batter to Their Partners JIV.pd

Reduction of quartz to silicon monoxide by methane-hydrogen mixtures

The reduction of quartz was studied isothermally in a fluidized bed reactor using continuously flowing methane-hydrogen gas mixture in the temperature range from 1623 K to 1773 K (1350 °C to 1500 °C). The CO content in the off-gas was measured online using an infrared gas analyzer. The main phases of the reduced samples identified by XRD analysis were quartz and cristobalite. Significant weight loss in the reduction process indicated that the reduction products were SiO and CO. Reduction of SiO2 to SiO by methane starts with adsorption and dissociation of CH4 on the silica surface. The high carbon activity in the CH4-H2 gas mixture provided a strongly reducing condition. At 1623 K (1350 °C), the reduction was very slow. The rate and extent of reduction increased with the increasing temperature to 1723 K (1450 °C). A further increase in temperature to 1773 K (1500 °C) resulted in a decrease in the rate and extent of reduction. An increase in the gas flow rate from 0.4 to 0.8 NL/min and an increase in the methane content in the CH4-H2 gas mixture from 0 to 5 vol pct facilitated the reduction. Methane content in the gas mixture should be maintained at less than 5 vol pct in order to suppress methane cracking

De geprotocolleerde Interapy-behandeling van depressie via het internet; resultaten van een gerandomiseerde trial

Psychologische behandelingen via internet bieden een nieuwe mogelijkheid voor de geestelijke gezondheidszorg. In samenwerking met de Stichting Mentrum ggz Amsterdam heeft Interapy een behandeling voor depressie via internet opgezet. De behandeling bestaat uit cognitief-gedragstherapeutische interventies, zoals psycho-educatie, schrijfopdrachten, registratie, activatie, het uitdagen van negatieve automatische gedachten en terugvalpreventie. Dit artikel beschrijft de procedure, de behandeling en de resultaten van een vergelijkende studie onder cliënten die matig tot ernstig depressief waren. De cliënten die direct actief werden behandeld (N = 32) verbeterden significant meer dan de cliënten in de psycho-educatieconditie (N = 14). Deze tweede groep kreeg de actieve behandeling ongeveer twaalf weken later. De effecten waren groot. In de actief behandelde groep liet 75 procent van de cliënten klinisch relevante verbetering zien, in de psycho-educatieconditie was dat percentage 36. Uit de follow-up na zes weken bleek dat de verbeteringen standhielden

Mitochondrial Release of Caspase-2 and -9 during the Apoptotic Process

The barrier function of mitochondrial membranes is perturbed early during the apoptotic process. Here we show that the mitochondria contain a caspase-like enzymatic activity cleaving the caspase substrate Z-VAD.afc, in addition to three biological activities previously suggested to participate in the apoptotic process: (a) cytochrome c; (b) an apoptosis-inducing factor (AIF) which causes isolated nuclei to undergo apoptosis in vitro; and (c) a DNAse activity. All of these factors, which are biochemically distinct, are released upon opening of the permeability transition (PT) pore in a coordinate, Bcl-2–inhibitable fashion. Caspase inhibitors fully neutralize the Z-VAD.afc–cleaving activity, have a limited effect on the AIF activity, and have no effect at all on the DNase activities. Purification of proteins reacting with the biotinylated caspase substrate Z-VAD, immunodetection, and immunodepletion experiments reveal the presence of procaspase-2 and -9 in mitochondria. Upon induction of PT pore opening, these procaspases are released from purified mitochondria and become activated. Similarly, upon induction of apoptosis, both procaspases redistribute from the mitochondrion to the cytosol and are processed to generate enzymatically active caspases. This redistribution is inhibited by Bcl-2. Recombinant caspase-2 and -9 suffice to provoke full-blown apoptosis upon microinjection into cells. Altogether, these data suggest that caspase-2 and -9 zymogens are essentially localized in mitochondria and that the disruption of the outer mitochondrial membrane occurring early during apoptosis may be critical for their subcellular redistribution and activation

Wnt signalling and cancer stem cells

[Abstract] Intracellular signalling mediated by secreted Wnt proteins is essential for the establishment of cell fates and proper tissue patterning during embryo development and for the regulation of tissue homeostasis and stem cell function in adult tissues. Aberrant activation of Wnt signalling pathways has been directly linked to the genesis of different tumours. Here, the components and molecular mechanisms implicated in the transduction of Wnt signal, along with important results supporting a central role for this signalling pathway in stem cell function regulation and carcinogenesis will be briefly reviewed.Ministerio de Ciencia e Innovación; SAF2008-0060