267 research outputs found

    Bostonia

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    Founded in 1900, Bostonia magazine is Boston University's main alumni publication, which covers alumni and student life, as well as university activities, events, and programs

    Behavioral Marital Therapy: An Evaluation of Treatment Effects Across High and Low Risk Settings

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    The present study examined the generalization of treatment effects of a cognitive- behavioral treatment program for marital distress. Following a baseline phase, each of four couples received two phases of marital therapy within a multiple baseline across subject design. The first phase of treatment was behavioral marital therapy (BMT) focusing on communication and problem solving skills. The second phase was cognitive- behavioral marital therapy (CBMT) which focused on conflict management skills in high risk interactive settings at home. Couples’ communication was assessed in a training setting in the clinic and each of two generalization probe settings at home (a low risk and a high risk) setting. The BMT phase produced a clear reduction in communication negativity in the training setting which generalized to both the low and the high risk setting. The CMBT phase produced little additional changes in communication, however, it was associated with changes on a measure of positive and negative partner- referent thoughts

    Bedrock geology of Vergennes Quadrangle, Perry and Jackson Counties, Illinois

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    Relief shown by contours and spot heightsIncludes location map and index to adjoining quadranglesIncludes bibliographical references (p. 8-9 of pamphlet

    Bedrock topography of Murphysboro Quadrangle, Jackson County, Illinois

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    Relief shown by contours and spot heights"Geology based on field work by Russell J. Jacobsen, F. Brett Denny, and Gary W. Griffith, 2006-2007.""Digital cartography by Jane E.J. Domier, Shannon M. Geegan, and Steve M. Radil, Illinois State Geological Survey.""Base map compiled by Illinois State Geological Survey ... ."Includes location map and index to adjoining quadrangle

    Bedrock geology of Murphysboro Quadrangle, Jackson County, Illinois

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    Relief shown by contours and spot heights"Geology based on field work by R. Jacobsen, B. Denny, and G. Griffith, 2006-2007.""Digital cartography by J. Domier, S. Geegan, and S. Radil, Illinois State Geological Survey.""Base map compiled by Illinois State Geological Survey ... ."Sheet 2 includes 1 stratigraphic column, 1 cross section, and 10 sectionsIncludes location map and index to adjoining quadrangle

    Bedrock geology of Valmeyer quadrangle, Monroe County, Illinois

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    "Geology based on field work by F. Brett Denny and Russel[l] J. Jacobson, 2001-2002."Relief shown by contours and spot heights"Ã 2009 University of Illinois Board of Trustees.""Digital cartography by Jane E.J. Domier, Steven M. Radil, and Alex J. Beata, Illinois State Geological Survey."Includes index to adjoining quadrangles and location mapData sheet includes text, 1 stratigraphic column, and 1 cross sectionIncludes bibliographical references (data sheet

    Effect of analgesic therapy on clinical outcome measures in a randomized controlled trial using client-owned dogs with hip osteoarthritis

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    BACKGROUND: Pain and impaired mobility because of osteoarthritis (OA) is common in dogs and humans. Efficacy studies of analgesic drug treatment of dogs with naturally occurring OA may be challenging, as a caregiver placebo effect is typically evident. However, little is known about effect sizes of common outcome-measures in canine clinical trials evaluating treatment of OA pain. Forty-nine client-owned dogs with hip OA were enrolled in a randomized, double-blinded placebo-controlled prospective trial. After a 1 week baseline period, dogs were randomly assigned to a treatment (ABT-116 – transient receptor potential vanilloid 1 (TRPV1) antagonist, Carprofen – non-steroidal anti-inflammatory drug (NSAID), Tramadol - synthetic opiate, or Placebo) for 2 weeks. Outcome-measures included physical examination parameters, owner questionnaire, activity monitoring, gait analysis, and use of rescue medication. RESULTS: Acute hyperthermia developed after ABT-116 treatment (P < 0.001). Treatment with carprofen (P ≤ 0.01) and tramadol (P ≤ 0.001) led to improved mobility assessed by owner questionnaire. Nighttime activity was increased after ABT-116 treatment (P = 0.01). Kinetic gait analysis did not reveal significant treatment effects. Use of rescue treatment decreased with treatment in the ABT-116 and Carprofen groups (P < 0.001). Questionnaire score and activity count at the end of treatment were correlated with age, clinical severity at trial entry, and outcome measure baseline status (S(R) ≥ ±0.40, P ≤ 0.005). Placebo treatment effects were evident with all variables studied. CONCLUSION: Treatment of hip OA in client-owned dogs is associated with a placebo effect for all variables that are commonly used for efficacy studies of analgesic drugs. This likely reflects caregiver bias or the phenomenon of regression to the mean. In the present study, outcome measures with significant effects also varied between groups, highlighting the value of using multiple outcome measures, as well as an a priori analysis of effect size associated with each measure. Effect size data from the present study could be used to inform design of future trials studying analgesic treatment of canine OA. Our results suggest that analgesic treatment with ABT-116 is not as effective as carprofen or tramadol for treatment of hip arthritis pain in client-owned dogs

    Black Hole Final State Conspiracies

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    The principle that unitarity must be preserved in all processes, no matter how exotic, has led to deep insights into boundary conditions in cosmology and black hole theory. In the case of black hole evaporation, Horowitz and Maldacena were led to propose that unitarity preservation can be understood in terms of a restriction imposed on the wave function at the singularity. Gottesman and Preskill showed that this natural idea only works if one postulates the presence of "conspiracies" between systems just inside the event horizon and states at much later times, near the singularity. We argue that some AdS black holes have unusual internal thermodynamics, and that this may permit the required "conspiracies" if real black holes are described by some kind of sum over all AdS black holes having the same entropy.Comment: Various minor improvements, references added, 25 page

    De Sitter and Schwarzschild-De Sitter According to Schwarzschild and De Sitter

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    When de Sitter first introduced his celebrated spacetime, he claimed, following Schwarzschild, that its spatial sections have the topology of the real projective space RP^3 (that is, the topology of the group manifold SO(3)) rather than, as is almost universally assumed today, that of the sphere S^3. (In modern language, Schwarzschild was disturbed by the non-local correlations enforced by S^3 geometry.) Thus, what we today call "de Sitter space" would not have been accepted as such by de Sitter. There is no real basis within classical cosmology for preferring S^3 to RP^3, but the general feeling appears to be that the distinction is in any case of little importance. We wish to argue that, in the light of current concerns about the nature of de Sitter space, this is a mistake. In particular, we argue that the difference between "dS(S^3)" and "dS(RP^3)" may be very important in attacking the problem of understanding horizon entropies. In the approach to de Sitter entropy via Schwarzschild-de Sitter spacetime, we find that the apparently trivial difference between RP^3 and S^3 actually leads to very different perspectives on this major question of quantum cosmology.Comment: 26 pages, 8 figures, typos fixed, references added, equation numbers finally fixed, JHEP versio
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