Innovation and implementation of new technologies in organizations

Dybdebasert master, 120 studiepoeng. Spesialisering økonomi.Formålet med studien er å beskrive og forstå hvordan innovasjonsprosessen utfolder seg i en organisasjon, slik at vi kan danne grunnlag for å vurdere hvordan kontekstuelle variasjoner påvirker adopsjon og opplevelse hos brukere av en ny teknologi. Problemstillingen er derfor som følger: Hvordan kan kontekstuelle variasjoner virke hemmende eller fremmende for innovasjonsprosessen ved implementering av ny teknologi i organisasjoner? Gjennom en casestudie fikk vi tilgang til både prosjektprosessen, men også hvordan brukere av teknologien har opplevd design, utforming, implementering og bruk. Vi har gjennomført 14 semistrukturerte intervjuer, hvorav to med produktkteiere og 11 med brukere. I tillegg har vi fått tilgang til prosjektdokumentasjon. Vi identifiserte både adopters og non-adopters blant informantene, hvilket bidro til at vi kunne drøfte både enablers og barrierer for adopsjon. Samtidig fremkom det at IT-systemet i casen bestod av to ulike funksjoner, hvor vi fant ulik grad av adopsjon for de to bruksområdene. Dette åpnet ytterligere for å sammenligne og drøfte hvordan prosjekt- og utviklingsprosessen hadde påvirket adopsjon og brukeropplevelse. Vi har gjennomført den teoretiske analysen med bakgrunn i både Diffusion of Innovations og Innovations Translation Model. De to analytiske rammeverkene bidro til å belyse empirien med konfronterende perspektiver, hvilket har gitt et bredere bilde av hvilke forhold som påvirker adopsjon og bruk. Våre funn viser at en innovasjons egenskaper ikke kan forstås uten å samtidig se på hvilke kontekstuelle forutsetninger som danner grunnlaget for utvikling og bruk av IT-systemet. Dette kan forklares ved at samhandling mellom aktører varierer i tid og rom, slik at bruksmønster omgjøres i samspill med konteksten. Våre funn bekrefter at innovasjonsprosessen preges av interaksjon, informasjonsdeling, samarbeid, tilpasning og fleksibilitet.Abstract (engelsk sammendrag) The purpose of this study is to describe and to understand how the innovation process unfold in organizations, so that we can provide a basis for assessing how contextual variations affects the adoption and user experience regarding new technology. The study is based on the following research question: How can contextual variations act as enablers or barriers for the innovation process when implementing new technologies in organizations? Through a case study we gained access to both the project process, but also how the users experienced the design, configuration, implementation, and use of the technology. We have conducted 14 semi-structured interviews, two of which were conducted with product owners and 11 with users. In addition to this, we have accessed project documentation. We identified both adopters and non-adopters among the interviewees, which helped us discuss both enablers and barriers for adoption. The IT-system also consisted of two different functions, where we found different degrees of adoption among the two different user areas. This provided opportunity to further compare and discuss how the project- and development process had impacted adoption and user experience. We have conducted the theoretical analysis based on both Diffusion of Innovations, and Innovations Translation Model. The two analytical frameworks helped to illustrate empirical confrontational perspectives, providing a wider view of the aspects that affect adoption and usage. Our findings suggest that the characteristics of an innovation cannot be understood without simultaneously looking at the contextual assumptions that form the basis for both the development and the usage of the IT system. This can be explained by how interaction between actors varies in time and space, so that usage patterns are transformed in conjunction with the context. We confirm that the innovation process is characterized by interaction, information sharing, collaboration, adaptation, and flexibility

Plastic recycling plant as a point source of microplastics to sediment and macroinvertebrates in a remote stream

Microplastic is now ubiquitous in freshwater, sediment and biota, globally. This is as a consequence of inputs from, for example, waste mismanagement, effluents from wastewater treatment plants and surface runoff from agricultural areas. In this study, we investigated point source pollution of plastic to an upland stream, originating from a recycling plant that recycles polyethylene film in a remote area of Norway. Sediment (~2 kg) and macroinvertebrates (549 individuals in total) were sampled at one site upstream and two sites downstream of the recycling plant to study microplastic deposition and food web uptake. In total, 340 microplastic films were identified through a combination of visual and µFTIR analysis in the sediment samples. This corresponded to a concentration of 0.23 (± 0.057) items per g sediment upstream of the plastic recycling plant and 0.45 (± 0.017) and 0.58 (± 0.34) items per g downstream. The dominant plastic polymer was polyethylene, which increased significantly downstream of the plastic recycling plant. This indicates the role of the plastic recycling plant as a point source for microplastic in this catchment. Among the three sites investigated, a fairly constant concentration of polypropylene was found, indicating a diffuse source of polypropylene films across the catchment possibly relating to low-intensity agricultural land-use. Low levels of polyethylene were also observed upstream, which may be linked to either local or longer-distance atmospheric transport. Despite the considerable presence of microplastic in sediments, concentrations in macroinvertebrates were extremely low with only a single microplastic particle identified in the total of 549 macroinvertebrates—belonging to three different feeding groups—investigated. Our study suggests that: 1) microplastic pollution can be transferred to remote areas as unintended losses from recycling facilities, 2) remote areas with limited land-use pressure still have detectable levels of microplastic and 3) microplastic is only taken up by stream macroinvertebrates to a limited degree despite relatively high sediment concentrations, and thus there are no strong indications for ecological risks posed by microplastic to this ecological group at this location.publishedVersio

CSF neurofilament light chain predicts 10-year clinical and radiologic worsening in multiple sclerosis

Background Neurofilament light chain (NfL) is an attractive biomarker of disease activity and progression in MS, but there is a lack in long-term prognostic data. Objective To test the long-term clinical and radiological prognostic value of cerebrospinal fluid (CSF)-NfL among newly diagnosed patients with MS. Methods Newly diagnosed MS patients where followed prospectively with baseline CSF-NfL and repeated MRI and clinical assessments for up to 10 years. Associations between baseline CSF-NfL and longitudinal MRI and clinical assessments were found by Generalized Estimating Equations analysis. Results Forty-two participants were included. CSF-NfL at baseline was significantly associated with the rate of atrophy in globus pallidus (p = 0.009) and hippocampus (p = 0.001) as evaluated by MRI. Baseline volumes of thalamus (β −0.33; 95% CI −0.57 to −0.10, p = 0.006), T1 (β 0.28; 95% CI 0.11 to 0.44, p = 0.001) and T2 (β 0.16; 95% CI 0.04 to 0.27, p = 0.008) lesions and baseline levels of CSF-NfL (β 0.9; 95% CI 0.3 to 1.5, p = 0.002) significantly predicted EDSS worsening over 10 years. Baseline CSF-NfL gave a comparable prediction to the best MRI volumetric predictors. Conclusion CSF-NfL predicted the clinical and radiological course of newly diagnosed patients with MS over a 10-year period, underlining its prognostic role.publishedVersio

Exposure to environmental phenols and parabens, and relation to body mass index, eczema and respiratory outcomes in the Norwegian RHINESSA study

Background Many phenols and parabens are applied in cosmetics, pharmaceuticals and food, to prevent growth of bacteria and fungi. Whether these chemicals affect inflammatory diseases like allergies and overweight is largely unexplored. We aimed to assess the associations of use of personal care products with urine biomarkers levels of phenols and paraben exposure, and whether urine levels (reflecting body burden of this chemical exposures) are associated with eczema, rhinitis, asthma, specific IgE and body mass index. Methods Demographics, clinical variables, and self-report of personal care products use along with urine samples were collected concurrently from 496 adults (48% females, median age: 28 years) and 90 adolescents (10–17 years of age) from the RHINESSA study in Bergen, Norway. Urine biomarkers of triclosan (TCS), triclocarban (TCC), parabens and benzophenone-3, bisphenols and dichlorophenols (DCP) were quantified by mass spectrometry. Results Detection of the urine biomarkers varied according to chemical type and demographics. TCC was detected in 5% of adults and in 45% of adolescents, while propyl (PPB) and methyl (MPB) parabens were detected in 95% of adults and in 94% (PPB) and 99% (MPB) of adolescents. Women had higher median urine concentrations of phenolic chemicals and reported a higher frequency of use of personal care products than men. Urine concentration of MPB increased in a dose-dependent manner with increased frequency of use of several cosmetic products. Overall, urinary biomarker levels of parabens were lower in those with current eczema. The biomarker concentrations of bisphenol S was higher in participants with positive specific IgE and females with current asthma, but did not differ by eczema or rhinitis status. MPB, ethylparaben (EPB), 2,4-DCP and TCS were inversely related to BMI in adults; interaction by gender were not significant. Conclusions Reported frequency of use of personal care products correlated very well with urine biomarker levels of paraben and phenols. Several chemicals were inversley related to BMI, and lower levels of parabens was observed for participants with current eczema. There is a need for further studies of health effects of chemicals from personal care products, in particular in longitudinally designed studies.publishedVersio

Brain atrophy and clinical characteristics predicting SDMT performance in multiple sclerosis: A 10-year follow-up study

Objectives To identify Magnetic Resonance Imaging (MRI), clinical and demographic biomarkers predictive of worsening information processing speed (IPS) as measured by Symbol Digit Modalities Test (SDMT). Methods Demographic, clinical data and 1.5 T MRI scans were collected in 76 patients at time of inclusion, and after 5 and 10 years. Global and tissue-specific volumes were calculated at each time point. For the primary outcome of analysis, SDMT was used. Results Worsening SDMT at 5-year follow-up was predicted by baseline age, Expanded Disability Status Scale (EDSS), SDMT, whole brain volume (WBV) and T2 lesion volume (LV), explaining 30.2% of the variance of SDMT. At 10-year follow-up, age, EDSS, grey matter volume (GMV) and T1 LV explained 39.4% of the variance of SDMT change. Conclusion This longitudinal study shows that baseline MRI-markers, demographic and clinical data can help predict worsening IPS. Identification of patients at risk of IPS decline is of importance as follow-up, treatment and rehabilitation can be optimized.publishedVersio

Association of oral bacteria with oral hygiene habits and self-reported gingival bleeding

Aim To describe associations of gingival bacterial composition and diversity with self-reported gingival bleeding and oral hygiene habits in a Norwegian regional-based population. Materials and Methods We examined the microbiome composition of the gingival fluid (16S amplicon sequencing) in 484 adult participants (47% females; median age 28 years) in the Respiratory Health in Northern Europe, Spain and Australia (RHINESSA) study in Bergen, Norway. We explored bacterial diversity and abundance differences by the community periodontal index score, self-reported frequency of gingival bleeding, and oral hygiene habits. Results Gingival bacterial diversity increased with increasing frequency of self-reported gingival bleeding, with higher Shannon diversity index for “always” β = 0.51 and “often” β = 0.75 (p < .001) compared to “never” gingival bleeding. Frequent gingival bleeding was associated with higher abundance of several bacteria such as Porphyromonas endodontalis, Treponema denticola, and Fretibacterium spp., but lower abundance of bacteria within the gram-positive phyla Firmicutes and Actinobacteria. Flossing and rinsing with mouthwash twice daily were associated with higher total abundance of bacteria in the Proteobacteria phylum but with lower bacterial diversity compared to those who never flossed or never used mouthwash. Conclusions A high frequency of self-reported gingival bleeding was associated with higher bacterial diversity than found in participants reporting no gingival bleeding and with higher total abundance of known periodontal pathogens such as Porphyromonas spp., Treponema spp., and Bacteroides spp.publishedVersio

Poor feeding opportunities and reduced condition factor for salmon post-smolts in the Northeast Atlantic Ocean

During the last few decades, many wild Atlantic salmon populations have declined dramatically. One possible contributing factor for the decline is reduced prey availability at sea. Here, we examine post-smolt diet and investigate if post-smolts show signs of selective feeding based on 2546 post-smolts sampled from west of Ireland to the northern Norwegian Sea over a 25-year period. We also test for changes over time in stomach fullness, diet, condition factor and body length. There was a clear reduction in condition factor for post-smolts sampled in the Norwegian Sea in the period 2003–2012. The post-smolt stomach fullness was also reduced in the same period. The reduction in condition factor is partly explained by reduced stomach fullness, including a reduction of highly energetic fish larvae and Amphipoda in the diet. Feeding on other prey, such as meso-zooplankton and insects, cannot substitute the high-quality fish larvae and Amphipoda in the post-smolt diet. This is the first study to document how salmon post-smolts feeding in the Norwegian Sea are affected by reduced feeding conditions. Possible causes for the observed changes in post-smolt feeding are ocean warming, decreased primary productivity, and reduced recruitment of important fish larvae.publishedVersio