A Conductometric Study of The Influence of Concentration And Temperature On The Reaction Velocity of 2,4-Dinitrochlorobenzene With Piperidine in 95 Per Cent Ethanol

The reaction kinetics of 2,4-dinitrochlorobenzene and piperidine in 95 per cent ethanol were determined by a Kohlrausch conductometric technique. A 1000 cps audiofrequency oscillator was used with both headphones and oscilloscope employed as null-point detectors. Three temperatures and concentrations were used with average specific rate constants of 0.3188, 1.744, and 4.423 liters mole-1 minute-1 at 0.2°C, 25°C, and 40°C respectively. The change in entropy was -21.84 cal. deg.-1 mole-1 and the activitation energy was 10.58 Kcal

Stability Ball Sitting Versus Chair Sitting During Sub-maximal Arm Ergometry

Purpose: It was predicted that sitting on a stability ball during arm ergometry would elevate cardiovascular parameters when compared to sitting on a chair and that this would be associated with greater recruitment of trunk and leg skeletal muscles. Methods: Open-circuit spirometry, video taping, blood pressure, heart rate, and EMG were conducted during rest and four minute stages of 15 W, 30 W, and 45 W using a Monark arm ergometer. Twenty-six apparently healthy adults exercised twice, once sitting on a stability ball and the other sitting on a chair (order randomized), with 45 to 60 minutes of rest between. ANOVA for repeated measures and paired-t testing were used for analysis. Results: Oxygen consumption was significantly 10 to 16% higher during exercise while sitting on the stability ball. There were no significant differences between sitting modes for heart rate, SBP, and DBP. Also, resting and exercise rectus femoris and 45 W external oblique EMGs were significantly higher on the stability ball. Finally, the knee was significantly more extended with the feet farther apart and more forward on the stability ball. Conclusion: The stability ball significantly elevates oxygen consumption during sub-maximal arm cranking without significantly increasing heart rate or blood pressure and this is associated with increased thigh muscle activation and lower leg repositioning

Predispositions and the Political Behavior of American Economic Elites: Evidence from Technology Entrepreneurs

Economic elites regularly seek to exert political influence. But what policies do they support? Many accounts implicitly assume economic elites are homogeneous and that increases in their political power will increase inequality. We shed new light on heterogeneity in economic elites' political preferences, arguing that economic elites from an industry can share distinctive preferences due in part to sharing distinctive predispositions. Consequently, how increases in economic elites' influence affect inequality depends on which industry's elites are gaining influence and which policy issues are at stake. We demonstrate our argument with four original surveys, including the two largest political surveys of American economic elites to date: one of technology entrepreneurs—whose influence is burgeoning—and another of campaign donors. We show that technology entrepreneurs support liberal redistributive, social, and globalistic policies but conservative regulatory policies—a bundle of preferences rare among other economic elites. These differences appear to arise partly from their distinctive predispositions

The Strain-Encoded Relationship between PrPSc Replication, Stability and Processing in Neurons is Predictive of the Incubation Period of Disease

Prion strains are characterized by differences in the outcome of disease, most notably incubation period and neuropathological features. While it is established that the disease specific isoform of the prion protein, PrPSc, is an essential component of the infectious agent, the strain-specific relationship between PrPSc properties and the biological features of the resulting disease is not clear. To investigate this relationship, we examined the amplification efficiency and conformational stability of PrPSc from eight hamster-adapted prion strains and compared it to the resulting incubation period of disease and processing of PrPSc in neurons and glia. We found that short incubation period strains were characterized by more efficient PrPSc amplification and higher PrPSc conformational stabilities compared to long incubation period strains. In the CNS, the short incubation period strains were characterized by the accumulation of N-terminally truncated PrPSc in the soma of neurons, astrocytes and microglia in contrast to long incubation period strains where PrPSc did not accumulate to detectable levels in the soma of neurons but was detected in glia similar to short incubation period strains. These results are inconsistent with the hypothesis that a decrease in conformational stability results in a corresponding increase in replication efficiency and suggest that glia mediated neurodegeneration results in longer survival times compared to direct replication of PrPSc in neurons

Press Release - Senator Edmund S. Muskie Disputes a Story of Deadlock on Drug Abuse Legislation

Senators Javits, Percy, Gurney, Ribicoff, Hughes, and Muskie issued a statement disputing a New York Times news report which asserted that a deadlock existed between the Congress and the White House over pending drug abuse control legislation

Establishment of \u3cem\u3eLeucaena leucocephala\u3c/em\u3e cv. Tarramba in Eastern Indonesia

The adaptability and productive value of Leucaena leucocephala cv. Tarramba (Tarramba) in eastern Indonesia has been observed since 2001 (Nulik et al. 2004), with many farmers and other stakeholders currently requesting seed for planting. Tarramba has greater forage and timber production, and psyllid tolerance than other commercial cultivars and locally grown leucaena. The variability of soils and climate in eastern Indonesia means that establishment techniques specific to the region are required to achieve maximum adoption and utilisation of Tarramba

Radiostereometric Analysis of Tantalum vs. Titanium Acetabular Shells in Young THR Patients

Introduction: In the active total hip replacement (THR) population, maintaining acetabular component stability and limiting polyethylene wear are crucial components to preventing premature implant failure. Titanium with Co/Cr/Mo fiber metal coating is among the most common materials used in cementless THR. Trabecular metal, composed of porous tantalum, has a metallic strut design resembling trabecular bone, designed to improve tissue infiltration and limit migration. This study assesses the stability and clinical outcomes of tantalum versus titanium acetabular shells using radiostereometric analysis (RSA) technology. Methods: In this IRB approved, prospective, randomized, blinded study, 46 patients received a primary THR by a single surgeon (DCA). Each patient was randomized to receive a titanium (23) (Trilogy, Zimmer) or tantalum (23) (Modular tantalum shell, Zimmer) uncemented hemispheric cup and either a highly-crosslinked or conventional polyethylene liner. Tantalum RSA markers were implanted around the liner periphery, femur, and periacetabular bone in each patient. RSA examinations, Harris Hip, UCLA, WOMAC, SF-36 scores were obtained at 10 days, 6 months, and annually with the furthest patients evaluated through 5 years. Results: Median translation was greater at all time points for the tantalum mesh cups except for the 3-year follow-up, however due to large standard errors, there was no significant difference between the two designs (p\u3e0.05). These large standard errors were predominantly caused by two outliers, neither of which had clinical evidence of loosening at 5 years follow-up. Mean UCLA, WOMAC, Harris Hip, and SF-36 PCS and MCS scores improved similarly in both groups. Conclusions: In this young THR population, both titanium and tantalum acetabular shells demonstrated excellent stability at five years follow up. Tantalum shells demonstrated slightly greater micromotion, but there was no statistically significant difference in shell migration. Outstanding clinical outcomes with statistically significant improvements in function and pain relief were observed in both groups