Anne Logan, Feminism and Criminal Justice. A Historical Perspective

Far from emerging in academic departments in the 1970s/80s, Anne Logan’s book demonstrates extremely convincingly that what can be termed a feminist criminological critique was alive, kicking and increasingly influential in England from the mid-nineteenth century onwards. It was located in women’s associational culture and its social significance lay in the real successes achieved by its campaigns for criminal justice reform. The origins of this movement are of course well-charted; Logan’s in..

Martin J. Wiener, Men of Blood: Violence, Manliness and Criminal Justice in Victorian England

Whilst the study of Victorian masculinity has highlighted attempts to replace libertinism and pugilism with chivalric and heroic models, its significance for criminal justice history is only just beginning to be felt in published work. Historians of sexuality, such as Ed Cohen and Angus McClaren, have shown that the spectacle of the criminal trial constituted one arena in which normative heterosexual masculinities were contested, debated and reinforced in the late nineteenth century. Many sta..

Martin J. Wiener, Men of Blood: Violence, Manliness and Criminal Justice in Victorian England

Whilst the study of Victorian masculinity has highlighted attempts to replace libertinism and pugilism with chivalric and heroic models, its significance for criminal justice history is only just beginning to be felt in published work. Historians of sexuality, such as Ed Cohen and Angus McClaren, have shown that the spectacle of the criminal trial constituted one arena in which normative heterosexual masculinities were contested, debated and reinforced in the late nineteenth century. Many sta..

Anne Logan, Feminism and Criminal Justice. A Historical Perspective

Far from emerging in academic departments in the 1970s/80s, Anne Logan’s book demonstrates extremely convincingly that what can be termed a feminist criminological critique was alive, kicking and increasingly influential in England from the mid-nineteenth century onwards. It was located in women’s associational culture and its social significance lay in the real successes achieved by its campaigns for criminal justice reform. The origins of this movement are of course well-charted; Logan’s in..

Does directly administered antiretroviral therapy represent good value for money in sub-Saharan Africa? A cost-utility and value of information analysis

Successful antiretroviral therapy (ART) relies on the optimal level of ART adherence to achieve reliable viral suppression, avert HIV drug resistance, and prevent avoidable deaths. It has been shown that there are various groups of people living with HIV at high-risk of non-adherence to ART in sub-Saharan Africa. The objective of this study was to examine the cost effectiveness and value-of-information of directly administered antiretroviral therapy (DAART) versus self-administered ART among people living with HIV, at high risk of non-adherence to ART in sub-Saharan Africa. Methods and findings A Markov model was developed that describes the transition between HIV stages based on the CD4 count, along with direct costs, quality of life and the mortality rate associated with DAART in comparison with self-administered ART. Data used in the model were derived from the published literature. A health system perspective was employed using a life-time time horizon. Probabilistic sensitivity analysis was performed to determine the impact of parameter uncertainty. Value of information analysis was also conducted. The expected cost of self-administered ART and DAART were $5,200 and$15,500 and the expected QALYs gained were 8.52 and 9.75 respectively, giving an incremental cost effectiveness ratio of $8,400 per QALY gained. The analysis demonstrated that the annual cost DAART needs to be priced below$200 per patient to be cost-effective. The probability that DAART was cost-effective was 1% for a willingness to pay threshold of $5,096 for sub-Saharan Africa. The value of information associated with the cost of DAART and its effectiveness was substantial. Conclusions From the perspective of the health care payer in sub-Saharan Africa, DAART cannot be regarded as cost-effective based on current information. The value of information analysis showed that further research will be worthwhile and potentially cost-effective in resolving the uncertainty about whether or not to adopt DAART

Campaigning against workplace ‘sexual harassment’ in the UK:Law, discourse and the news press c. 1975 – 2005

This article examines how and in what ways workplace ‘sexual harassment’ achieved social and legal recognition in the UK news press following its importation from North America in the mid-1970s. It assesses the role of feminist campaigners working within institutions (trade unions, human rights advocacy, the Equal Opportunities Commission and journalism itself) in shifting public discourse and in using the media to educate and promote social change. We demonstrate that the trajectory was far from a linear progression. Initial hostility within the popular press in the early 1980s was replaced with sympathetic coverage across the party-political spectrum by 1990. However, this consensus broke down in the 1990s as a result of politicised and polarised coverage of a series of claims brought by women in the services and armed forces against the backdrop of debates about ‘compensation culture’ and membership of the European Union. Whilst change was effected at the level of employment law, formal practice and in the human resources policies of larger employers, ‘sexual harassment myths’ were resilient as a thread within ‘everyday cultural discourse’ and, by implication, within informal workplace cultures

Exploring the costs and outcomes of sexually transmitted infection (STI) screening interventions targeting men in football club settings: preliminary cost-consequence analysis of the SPORTSMART pilot randomised controlled trial

Background: The objective of this study was to compare the costs and outcomes of two sexually transmitted infection (STI) screening interventions targeted at men in football club settings in England, including screening promoted by team captains. Methods: A comparison of costs and outcomes was undertaken alongside a pilot cluster randomised control trial involving three trial arms: (1) captain-led and poster STI screening promotion; (2) sexual health advisor-led and poster STI screening promotion and (3) poster-only STI screening promotion (control/comparator). For all study arms, resource use and cost data were collected prospectively. Results: There was considerable variation in uptake rates between clubs, but results were broadly comparable across study arms with 50% of men accepting the screening offer in the captain-led arm, 67% in the sexual health advisor-led arm and 61% in the poster-only control arm. The overall costs associated with the intervention arms were similar. The average cost per player tested was comparable, with the average cost per player tested for the captain-led promotion estimated to be £88.99 compared with £88.33 for the sexual health advisor-led promotion and £81.87 for the poster-only (control) arm. Conclusions: Costs and outcomes were similar across intervention arms. The target sample size was not achieved, and we found a greater than anticipated variability between clubs in the acceptability of screening, which limited our ability to estimate acceptability for intervention arms. Further evidence is needed about the public health benefits associated with screening interventions in non-clinical settings so that their cost-effectiveness can be fully evaluated

The evolutionary dynamics of variant antigen genes in Babesia reveal a history of genomic innovation underlying host-parasite interaction

Babesia spp. are tick-borne, intraerythrocytic hemoparasites that use antigenic variation to resist host immunity, through sequential modification of the parasite-derived variant erythrocyte surface antigen (VESA) expressed on the infected red blood cell surface. We identified the genomic processes driving antigenic diversity in genes encoding VESA (ves1) through comparative analysis within and between three Babesia species, (B. bigemina, B. divergens and B. bovis). Ves1 structure diverges rapidly after speciation, notably through the evolution of shortened forms (ves2) from 5′ ends of canonical ves1 genes. Phylogenetic analyses show that ves1 genes are transposed between loci routinely, whereas ves2 genes are not. Similarly, analysis of sequence mosaicism shows that recombination drives variation in ves1 sequences, but less so for ves2, indicating the adoption of different mechanisms for variation of the two families. Proteomic analysis of the B. bigemina PR isolate shows that two dominant VESA1 proteins are expressed in the population, whereas numerous VESA2 proteins are co-expressed, consistent with differential transcriptional regulation of each family. Hence, VESA2 proteins are abundant and previously unrecognized elements of Babesia biology, with evolutionary dynamics consistently different to those of VESA1, suggesting that their functions are distinct

Mechanisms of Pacific Summer Water variability in the Arctic's Central Canada Basin

© The Author(s), 2014. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Journal of Geophysical Research: Oceans 119 (2014): 7523–7548, doi:10.1002/2014JC010273.Pacific Water flows northward through Bering Strait and penetrates the Arctic Ocean halocline throughout the Canadian Basin sector of the Arctic. In summer, Pacific Summer Water (PSW) is modified by surface buoyancy fluxes and mixing as it crosses the shallow Chukchi Sea before entering the deep ocean. Measurements from Ice-Tethered Profilers, moorings, and hydrographic surveys between 2003 and 2013 reveal spatial and temporal variability in the PSW component of the halocline in the Central Canada Basin with increasing trends in integrated heat and freshwater content, a consequence of PSW layer thickening as well as layer freshening and warming. It is shown here how properties in the Chukchi Sea in summer control the temperature-salinity properties of PSW in the interior by subduction at isopycnals that outcrop in the Chukchi Sea. Results of an ocean model, forced by idealized winds, provide support to the mechanism of surface ocean Ekman transport convergence maintaining PSW ventilation of the halocline.Funding was provided by the National Science Foundation Division of Polar Programs under award 1107623, 1313614, 1107412, 1107277, 1303644, and 0938137 and by Yale University. ICMMG model development was supported by the Russian Fund for Basic Research (14-05-00730A)