Ignition and structure of a laminar diffusion flame in the field of a vortex

The distortion of flames in flows with vortical motion is examined via asymptotic analysis and numerical simulation. The model consists of a constant density, one step, irreversible Arrhenius reaction between initially unmixed species occupying adjacent half-planes which are then allowed to mix and react in the presence of a vortex. The evolution in time of the temperature and mass fraction fields is followed. Emphasis is placed on the ignition time and location as a function of vortex Reynolds number and initial temperature differences of the reacting species. The study brings out the influence of the vortex on the chemical reaction. In all phases, good agreement is observed between asymptotic analysis and the full numerical solution of the model equations

Role of acoustics in flame/vortex interactions

The role of acoustics in flame/vortex interactions is examined via asymptotic analysis and numerical simulation. The model consists of a one-step, irreversible Arrhenius reaction between initially unmixed species occupying adjacent half-planes which are allowed to mix and react by convection and diffusion in the presence of an acoustic field or a time-varying pressure field of small amplitude. The main emphasis is on the influence of the acoustics on the ignition time and flame structure as a function of vortex Reynolds number and initial temperature differences of the reactants

The Effects of the Get Off Your Rocker Exercise Class on Balance for Patients following a CVA: A Case Study Approach

Background and Purpose: Cerebral vascular accident (CV A) is the leading cause of serious, long-term disability and the third leading cause of death in the United States. It is estimated that approximately 75% of people who have a stroke survive, many of whom live with some level of impairments that impact their activities of daily living and quality of life. One of the results of these impairments can be decreased balance. Limitations in balance may impact an individual\u27s risk of falls, ability to ambulate, and performance of functional activities. Exercises emphasizing balance training playa significant role in improving postural control. The purpose of this study is to determine if the six -week Get Off Your Rocker balance exercise class improves balance and quality of life in people who have had a CV A and who live in the community. If the Get Off Your Rocker exercise class is found to be effective for this population, it can be an additional tool for physical therapists in improving balance. Subjects: The two subjects who participated in the study had a neurological diagnosis of CVA. Both subjects were older than 20 years of age, lived in the community, and ambulated independently. Methods: Four measures were used to gather data regarding balance and quality of life. During the initial testing session, subjects completed the Timed Up and Go, Functional Reach, Berg Balance Measure, and Short Form 36 Health Survey. Subjects then participated in the Get Off Your Rocker balance exercise class three times a week for six consecutive weeks. Following the exercise class, the assessment measures were repeated. Results: Subjects demonstrated both quantitative and qualitative improvements. Both participants showed improvements on all four of the measures. Conclusion: Following participation in the six-week Get Off Your Rocker balance exercise class, we concluded that it was beneficial in improving balance for people following a CVA. This class can be an effective tool for balance training and increasing functional capacities leading to enhanced quality of life

Hipopituitarismo e síndrome amenorreia-galactorreia causados por trombose de aneurisma carotídeo e da artéria carótida no pescoço: relato de caso

Giant intra and parasellar aneurysm with a spontaneous thrombosis of internal carotid artery is rare. We report the case of a 34 years old woman presenting a unique giant sellar and parasellar aneurysm associated with hypopituitarism and amenorrhea-galactorrhea syndrome. Computed tomographic scans and magnetic resonance images were suggestive of a sellar tumor with a cystic component. Digital cerebral angiography showed spontaneous thrombosis of a intrasellar and parasellar carotid artery aneurysm and left internal carotid artery in the neck. A transseptal endoscopic biopsy was done and confirmed a thrombosed aneurysm. No other surgical treatment was required in this patient but permanent endocrinological treatment was necessary.Aneurismas selares e paraselares gigantes com trombose da artéria carótida cervical e intracraniana são raros. Apresentamos o caso de mulher de 34 anos apresentando hipopituitarismo e síndrome amenorréia-galactorréia. A tomografia computadorizada craniana e a ressonância magnética foram sugestivas de tumor selar com componente cístico. Angiografia digital cerebral mostrou aneurisma único gigante selar e parasselar e trombose completa da artéria carótida comum esquerda no pescoço. A biopsia transeptal endoscópica da lesão mostrou tratar-se de aneurisma carotídeo trombosado. Não foi realizado nenhum outro tratamento cirúrgico na paciente, mas apenas tratamento endocrinológico de reposição.Fortaleza General Hospital Department of NeuroendocrinologyUniversidade Federal de São Paulo (UNIFESP), Escola Paulista de Medicina (EPM)Federal University of Ceará Department of AnesthesiologyFortaleza General Hospital Department of Neck and Head SurgeryUNIFESP, EPMSciEL

Wagging the Dogma Tissue-Specific Cell Cycle Control in the Mouse Embryo

AbstractThe family of cyclin-dependent kinases (Cdks) lies at the core of the machinery that drives the cell division cycle. Studies in cultured mammalian cells have provided insight into the cellular functions of many Cdks. Recent Cdk and cyclin knockouts in the mouse show that the functions of G1 cell cycle regulatory genes are often essential only in specific cell types, pointing to our limited understanding of tissue-specific expression, redundancy, and compensating mechanisms in the Cdk network

Relação entre pressão intra-selar e volume de tumor de hipófise

OBJECTIVE: To determine if there was a relationship between intrassellar pressure (ISP) and pituitary tumor volume. METHOD: Between August 2002 and May 2004, 60 patients aged between 13 and 75 years old (39 males), having a pituitary adenoma were submitted to an endoscope transseptal approach. During the surgery and before tumor resection, 2 mm of the sella s floor were removed and a 1.5 mm dural opening made to place a transducer into the pituitary adenoma. The transducer was connected to a pressure monitor. RESULTS: The intrasellar pressure, ranged from 2-51 mmHg and was measured based on the classification of Hardy-Vezina. The most elevated was in the type II macro adenomas with 32.6 mmHg, sharply superior to the value of a normal intracranial pressure. CONCLUSION: These values showed that the macroadenomas confined to the sella, without destruction of the floor and integrity of the diaphragm, type II of Hardy-Vezina, presented a value of ISP much higher than intra-extrasellar macroadenoma s.OBJETIVO: Determinar se existia uma relação entre a pressão intraselar (ISP) e o volume de tumor de hipófise. MÉTODO: Entre agosto de 2002 e maio de 2004, 60 pacientes com idades variando entre 13 e 75 anos (39 homens), portadores de adenoma hipofisários foram operados por via transesfenoidal. Durante o ato cirúrgico e antes da resseção do tumor, uma osteotomia de 2 mm foi realizada no assoalho selar e uma abertura de 1,5 mm na duramater para a introdução de um transdutor dentro do tumor. O transdutor foi conectado a um monitor de pressão e esta foi medida por 2 minutos. RESULTADOS: A pressão intra-selar variou entre 2-51 mmHg e a correlação entre tamanho do tumor e ISP foi baseada na classificação de Hardy-Vezina. A média da ISP mais elevada foi encontrada nos macroadenomas tipo II com 32,6 mmHg, nitidamente superior a pressão intra selar normal. CONCLUSÃO: Estes valores mostram que os macroadenomas confinados a sela sem destruição do assoalho selar e com integridade do diafragma, classificados como tipo II de Hardy-Vezina, apresentam uma ISP muito superior aos outros adenomas.Hospital of Fortaleza Neurosurgery Department GeneralFederal University of São Paulo Neurosurgery ServiceFederal University of CearáUNIFESP, Neurosurgery ServiceSciEL