64 research outputs found
Estrangeirismos e moda – exemplos das revistas e das páginas web portuguesas e polacas
Borrowings and fashion – examples from Portuguese and Polish magazines and web sites The main objective of this following paper is to present the loan words from Portuguese and Polish fashion magazines and websites. We are trying to describe the main characteristics of the vocabulary of fashion, with particular emphasis on loan words. Analyzing the women’s press articles and websites, we find a variety of borrowings, primarily from English. There are many words which have already integrated with Portuguese and Polish language well in the material we gathered. On the other hand there are words which are in the first phase of adoption as well as those which are used only once mostly because of their style. There are some cases where loan words are very difficult for readers
Empréstimos do inglês na língua cabo-verdiana no presente e no passado
The main objective of the present study is to observe the influence of English on the Cape Verdean language, taking into account the historical events and the linguistic contacts between the languages in question. It is intended to observe how Anglicisms have been introduced in different contexts, especially in recent times, therefore, without forgetting the British and American influence in Cape Verde in past centuries and its impact on the lexicon. The semantic fields covered include, among others, new technologies, sports and music (rap kriol). The present descriptive research is based mainly on digital sources, such as social networks, online press, dictionaries available online and song texts. In conclusion, the analysis carried out proves the constant presence of Anglicisms in Cape Verdean reality, as well as their flow related to the emergence of new phenomena that need to be named.The main objective of the present study is to observe the influence of English on the Cape Verdean language, taking into account the historical events and the linguistic contacts between the languages in question. It is intended to observe how Anglicisms have been introduced in different contexts, especially in recent times, therefore, without forgetting the British and American influence in Cape Verde in past centuries and its impact on the lexicon. The semantic fields covered include, among others, new technologies, sports and music (rap kriol). The present descriptive research is based mainly on digital sources, such as social networks, online press, dictionaries available online and song texts. In conclusion, the analysis carried out proves the constant presence of Anglicisms in Cape Verdean reality, as well as their flow related to the emergence of new phenomena that need to be named
Survivin antiapoptotic gene expression as a prognostic factor in non-small cell lung cancer: in situ hybridization study.
Survivin is an inhibitor of apoptosis that plays a significant role in cell cycle regulation and is important for survival prognosis in many neoplasms. Survivin expression was assessed by in situ hybridization (ISH) in 60 consecutive patients (54 males and 4 females) with NSCLC treated between 1993 and 1997. The examined patients had IIB and IIIA stage according to TNM system. In all cases the chemotherapy with cisplatin and etoposide (2 cycles) was administered prior the surgery; in patients responding to the therapy one more cycle was applied. Survivin gene overexpression was observed in 35 patients (58.3%). There was no correlation between survivin mRNA level and histological type of tumor, stage of cell differentiation, stage of disease according to TNM classification, performance status according to WHO and number of chemotherapy regimens administered (p > 0.05). However, the correlation between survivin gene expression and response to the chemotherapy was statistically significant (p = 0.04). Statistical analysis showed that median survival in patients with survivin gene overexpression was shorter (14.0 months) as compared to patients with no expression (60.0 months; p = 0.00002). In survival assessment by means of Kaplan-Meier test, 14.3% of five-year survival was achieved in the former group versus 60% in the latter (p = 0.00003). Univariate analysis (log-rank test) showed that significant independent prognostic factors in NSCLC included: stage of the disease according to TNM classification (p = 0.006), response to chemotherapy (p = 0.005) and pattern of survivin gene expression (p = 0.00003). Multivariate analysis utilizing Cox's model showed that for survival assessment the stage according to TNM, response to the chemotherapy and survivin expression estimated by means of ISH are of statistical significance (p=0.00001). The calculated predictive values showed that ISH technique was quite accurate in assessment of five-year survival. Our data show that survivin expression may be used as a prognostic factor and a target for therapy
242. Analiza ekspresji EGFR i angiogenezv w utkaniu niedrobnokomórkowego raka płuc oraz związku z czasem przeżycia pacjentów w stadiach zaawansowania klinicznego I-IIIA
Cel pracyWciąż niezadowalające wskaźniki przeżycia pacjentów z rakiem płuca, mimo radykalnego leczenia operacyjnego, skłaniają do poszukiwań nowych czynników prognostycznych. Wiadomym jest, że receptor naskórkowego czynnika wzrostu (EGFR) wpływa na wzrost komórek guza i jego progresję, jak również tworzenie przerzutów – głównie poprzez oddziaływanie na tworzenie nowych naczyń krwionośnych. Jego prognostyczna rola u pacjentów z niedrobnokomórkowym rakiem płuca (NRP) jest niejasna. Natomiast gęstość naczyń krwionośnych (GNK), będąca miernikiem angiogenezy w guzie, jest podawana jako marker prognostyczny w wielu nowotworach. Celem naszego badania była ocena zależności między ekspresją EGFR i GNK w utkaniu guza nowotworowego a przeżyciem pacjentów z NRP.Materiał i metodyBadaniem objęto 75 pacjentów z NRP w stadiach zaawansowania klinicznego I-IIIA. Wycinki z guza pobierano z materiału operacyjnego, utrwalonego w formalinie. Na uzyskanych skrawkach parafinowych wykonywano odczyny immunohistochemiczne z zastosowaniem monoklonalnego przeciwciała przeciw receptorowi naskórkowego czynnika wzrostu oraz monoklonalnego przeciwciała przeciw CD31.WynikiWśród 75 pacjentów było 5 kobiet (6.7%) i 70 mężczyzn (93.3%) w wieku od 42 lat do 74 lat (średnio 59 lat). W badanej grupie chorych stwierdzono raka płaskonabłonkowego u 53 pacjentów (70.7%), gruczolakoraka u 11 chorych (14.7%) i raka wielkokomórkowego także u 11 pacjentów. Analizując uzyskane dane nie stwierdzono istotności statystycznej między ekspresją EGFR i czasem przeżycia pacjentów. Również GNK nie miała istotnego wpływu na przeżycie pacjentów. Jedynie stan węzłów chłonnych (cecha N; p<0.05), typ histologiczny raka (p<0.001) oraz wiek (p<0.05) w badanej grupie chorych miały istotny statystycznie wpływ na czas przeżycia.WnioskiUzyskane w tym badaniu wyniki nie są zgodne z wynikami innych doniesień mówiących o tym, że ekspresja EGFR i GNK w NRP mogą być traktowane jako czynniki prognostyczne. Należy jednak podkreślić, że analizowana grupa pacjentów była mała, a większość chorych (59 pacjentów, 78.7%) znajdowała się w stadium znacznego zaawansowania nowotworu
Carcinoid of the small intestine as a rare cause of gastrointestinal bleeding diagnosed with angio-CT examination of the abdominal cavity - case report
In this report a rare case of a bleeding carcinoid located in the ileum and diagnosed with an angio-CT
examination of the abdominal cavity is presented. An angio-CT examination of the abdominal cavity may
be an effective method of imaging diagnostics in cases of negative results of endoscopy and colonoscopy
examinations and, at the same time, a shortage of accessibility to double-balloon enteroscopy and capsule
endoscopy. It is possible to visualize bleeding lesions on condition that the outflow of the blood into the
digestive tract is above 1 ml per minute. The patient concerned was operated on in a scheduled course
following proper preparation. The perioperative course was uneventful and after a three-year follow-up
no features of the recurrence of neoplastic disease have been observed.W pracy przedstawiono rzadki przypadek krwawiącego rakowiaka jelita krętego rozpoznanego przy użyciu
angio-TK jamy brzusznej. Przy ujemnym wyniku panendoskopii i kolonoskopii oraz braku dostępności
enteroskopii dwubalonowej bądź kapsułki endoskopowej, angio-TK jamy brzusznej może być skuteczną
metodą diagnostyki obrazowej. Warunkiem uwidocznienia krwawiącej zmiany jest zachowany
wypływ krwi do przewodu pokarmowego powyżej 1 ml/min. Po przygotowaniu pacjentkę zoperowano
w trybie planowym. Przebieg okołooperacyjny był niepowikłany, a po trzyletnim okresie obserwacji nie
stwierdzono cech wznowy choroby nowotworowej
Operacja plastyczna przepukliny pachwinowej i resekcja wola guzowatego powikłane zespołem paciorkowcowego wstrząsu toksycznego (STSS) wywołanym przez Streptococcus pyogenes - opis dwóch przypadków
W niniejszej pracy przedstawiono dwa przypadki zespołu paciorkowcowego wstrząsu toksycznego (STSS)
po zabiegach plastyki przepukliny pachwinowej i subtotalnej resekcji wola guzowatego obojętnego. Oba
poważne powikłania leczenia chirurgicznego leczono na oddziale intensywnej terapii. W dochodzeniu
epidemiologicznym nie wykazano źródła zakażenia. Wdrożenie szeregu procedur profilaktycznych doprowadziło
do eliminacji tego typu zakażeń.This paper presents two cases of streptococcal toxic shock syndrome (STSS) after an inguinal hernioplasty
and a goiter subtotal resection. These serious complications of surgery were treated in our Intensive
Care Ward. An epidemiological investigation did not reveal the source of infection. STSS elimination
was achieved by antimicrobial procedures and prophylaxis
Brain iron accumulation in Wilson disease: a post-mortem 7 Tesla MRI - histopathological study
Aims: In Wilson disease (WD), T2/T2*-weighted (T2*w) MRI frequently shows hypointensity in the basal ganglia that is suggestive of paramagnetic deposits. It is currently unknown whether this hypointensity is related to copper or iron deposition. We examined the neuropathological correlate of this MRI pattern, particularly in relation to iron and copper concentrations. Methods: Brain slices from nine WD and six control cases were investigated using a 7T-MRI system. High resolution T2*w images were acquired and R2* parametric maps were reconstructed using a multi-gradient recalled echo sequence. R2* was measured in the globus pallidus (GP) and the putamen. Corresponding histopathological sections containing the lentiform nucleus were examined using Turnbull iron staining, and double staining combining Turnbull with immunohistochemistry for macrophages or astrocytes. Quantitative densitometry of the iron staining as well as copper and iron concentrations were measured in the GP and putamen and correlated to R2* values. Results: T2*w hypointensity in the GP and/or putamen was apparent in WD cases and R2* values correlated with quantitative densitometry of iron staining. In WD, iron and copper concentrations were increased in the putamen compared to controls. R2* was correlated with the iron concentration in the GP and putamen whereas no correlation was observed for the copper concentration. Patients with more pronounced pathological severity in the putamen displayed increased iron concentration, which correlated with an elevated number of iron-containing macrophages. Conclusions: T2/T2*w hypointensity observed in vivo in the basal ganglia of WD patients is related to iron rather than copper deposits
Neurochemical and Behavioral Characteristics of Toxic Milk Mice: An Animal Model of Wilson’s Disease
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