Indigenous and Non-Indigenous Paraprofessionals: An Empirical Comparison

This paper provides a comparative description of indigenous and nonindigenous paraprofessionals who were employed in a social service capacity in a large urban setting. Personal interviews were conducted with 88 paraprofessionals employed by the Fulton County Department of Family and Children Servives (Atlanta, Ga.). The primary variables discussed include an assessment of the respondent\u27s background, their present employment situation, experience with and attitudes toward welfare and general attitudinal measures. The results provide a basic demographic profile of the indigenous and non-indigenous paraprofessional and indicate their differing characteristics. Briefly, the indigenous respondents were less anomic, felt more efficacious in terms of helping clients, had a less favorable stance toward welfare, had less training and were considerably more more satisfied with their job than were their non-indigenous counterparts. Additionally, the implications of these findings and considerations which need to be explored in future research are discussed

Leadership Strategies for Sustaining Membership in Southern Baptist Churches

Church membership is declining, and the number of Americans identifying as having no religious affiliation is increasing. Church members can provide for a community’s spiritual and financial needs and promote the growth of evangelical believers and biblical stewardship. However, some pastors, ministerial staff, and ministry leaders lack effective leadership strategies to sustain membership. Grounded in transformational leadership theory, the purpose of this qualitative multiple case study was to explore leadership strategies Southern Baptist church leaders from three churches in Pennsylvania use to sustain membership. Participants were three church leaders who sustained church membership for 3 years or longer. Data were collected through semi-structured interviews and church documents and analyzed using thematic analysis. Four themes emerged: (a) understanding the vision, pastoral training; (b) being relational, maintaining youth membership, technology; (c) understanding and providing for the needs of the community; and (d) following up with members and nonmembers. A key recommendation is for church leaders to involve church members in projects to help members become active and engaged in the church’s vision. The implications for positive social change include the potential to enhance education and civic and social involvement in individuals, families, and communities

Breeding Small Grains as a Forage, Silage and Cover Crop for the Southern Coastal Plain (USA) in a Changing Climatic Environment

Forage breeding of small grains in the southern Coastal Plains region of the U.S. mimic many other countries experiencing climate changes and breeding strategies should be similar for improving small grains grown for forage, silage or as cover crops. Significant focus on improvements in stress-adaptation has encouraged members of the SunGrains cooperative to cross, evaluate and develop experimental lines with inherent adaptation to climatic conditions including heat stress, drought tolerance, short-day and long-day forage production periods, and flooded conditions for events with storm-related, short-term durations. Many new cultivars, grown throughout the southeastern U.S. have resulted from breeding selection under abiotic and biotic stresses, adapted to climate change and related concerns, such as disease and insect pests

Paget's disease of the breast in a male with lymphomatoid papulosis: a case report

<p>Abstract</p> <p>Introduction</p> <p>Paget's disease is an eczematous skin change of the nipple that is usually associated with an underlying breast malignancy. Male breast cancer represents only 1-3% of all breast malignancies and Paget's disease remains very rare.</p> <p>Case presentation</p> <p>We present the case of a 67-year-old Caucasian man with lymphomatoid papulosis who was diagnosed with Paget's disease of the nipple and who was treated successfully with surgery alone. We discuss the presentation, investigations, management and pathogenesis of Paget's disease of the nipple.</p> <p>Conclusion</p> <p>The case highlights the need to be vigilant when new skin lesions arise in the context of an underlying chronic skin disorder.</p

Soil bacterial and fungal communities of six bahiagrass cultivars

Background Cultivars of bahiagrass (Paspalum notatum Flüggé) are widely used for pasture in the Southeastern USA. Soil microbial communities are unexplored in bahiagrass and they may be cultivar-dependent, as previously proven for other grass species. Understanding the influence of cultivar selection on soil microbial communities is crucial as microbiome taxa have repeatedly been shown to be directly linked to plant performance. Objectives This study aimed to determine whether different bahiagrass cultivars interactively influence soil bacterial and fungal communities. Methods Six bahiagrass cultivars (‘Argentine’, ‘Pensacola’, ‘Sand Mountain’, ‘Tifton 9’, ‘TifQuik’, and ‘UF-Riata’) were grown in a randomized complete block design with four replicate plots of 4.6 × 1.8 m per cultivar in a Rhodic Kandiudults soil in Northwest Florida, USA. Three soil subsamples per replicate plot were randomly collected. Soil DNA was extracted and bacterial 16S ribosomal RNA and fungal ribosomal internal transcribed spacer 1 genes were amplified and sequenced with one Illumina Miseq Nano. Results The soil bacterial and fungal community across bahiagrass cultivars showed similarities with communities recovered from other grassland ecosystems. Few differences in community composition and diversity of soil bacteria among cultivars were detected; none were detected for soil fungi. The relative abundance of sequences assigned to nitrite-oxidizing Nitrospira was greater under ‘Sand Mountain’ than ‘UF-Riata’. Indicator species analysis revealed that several bacterial and fungal indicators associated with either a single cultivar or a combination of cultivars are likely to be plant pathogens or antagonists. Conclusions Our results suggest a low impact of plant cultivar choice on the soil bacterial community composition, whereas the soil fungal community was unaffected. Shifts in the relative abundance of Nitrospira members in response to cultivar choice may have implications for soil N dynamics. The cultivars associated with presumptive plant pathogens or antagonists indicates that the ability of bahiagrass to control plant pathogens may be cultivar-dependent, however, physiological studies on plant-microbe interactions are required to confirm this presumption. We therefore suggest that future studies should explore the potential of different bahiagrass cultivars on plant pathogen control, particularly in sod-based crop rotation

Do female association preferences predict the likelihood of reproduction?

Sexual selection acting on male traits through female mate choice is commonly inferred from female association preferences in dichotomous mate choice experiments. However, there are surprisingly few empirical demonstrations that such association preferences predict the likelihood of females reproducing with a particular male. This information is essential to confirm association preferences as good predictors of mate choice. We used green swordtails (&lt;i&gt;Xiphophorus helleri&lt;/i&gt;) to test whether association preferences predict the likelihood of a female reproducing with a male. Females were tested for a preference for long- or short-sworded males in a standard dichotomous choice experiment and then allowed free access to either their preferred or non-preferred male. If females subsequently failed to produce fry, they were provided a second unfamiliar male with similar sword length to the first male. Females were more likely to reproduce with preferred than non-preferred males, but for those that reproduced, neither the status (preferred/non-preferred) nor the sword length (long/short) of the male had an effect on brood size or relative investment in growth by the female. There was no overall preference based on sword length in this study, but male sword length did affect likelihood of reproduction, with females more likely to reproduce with long- than short-sworded males (independent of preference for such males in earlier choice tests). These results suggest that female association preferences are good indicators of female mate choice but that ornament characteristics of the male are also important

Release of a New Forage Bermudagrass Cultivar from the USDA-NPGS Cynodon Collection

Warm-season perennial grasses are the backbone of the pasture-based livestock industry in the southeastern USA. In Florida specifically, bahiagrass (Paspalum notatum Flugge) and bermudagrass (Cynodon spp.) support 1 million head of cattle and 15,000 beef cattle operations. Bermudagrass is the most widely planted forage species in the southeastern USA, planted in approximately 15 million ha and used for grazing, hay and silage. The genus Cynodon is native to southern Africa and germplasm collections have revealed a high degree of genetic variability within the genus. The United States Department of Agriculture National Plant Germplasm System (USDA-NPGS) maintains a collection of bermudagrass plant introduction (PIs) in Griffin, GA, USA and the USDA Georgia Coastal Plains Experiment Station, Tifton, GA, maintains additional forage germplasm. Multi-location trials were established in 2014 in four states (FL, GA, NC and OK) to screen the collection for herbage accumulation (HA) and nutritive value (NV). Due to the large genotype by environment interaction for HA across states, we focused on selecting accessions adapted to South Georgia and Florida. Several PIs showed improved HA and NV compared to ‘Tifton 85’ across several trials and years. Particularly, PI 316510 produced high HA in Citra, FL and Tifton, GA, had improved NV traits, and faster establishment compared to Tifton 85. We confirmed that PI 316510 is tetraploid by chromosome counts and flow cytometry. The PI 316510 has been released by the University of Florida under the name “Newell”

A Modern Mode of Activation for Nucleic Acid Enzymes

Through evolution, enzymes have developed subtle modes of activation in order to ensure the sufficiently high substrate specificity required by modern cellular metabolism. One of these modes is the use of a target-dependent module (i.e. a docking domain) such as those found in signalling kinases. Upon the binding of the target to a docking domain, the substrate is positioned within the catalytic site. The prodomain acts as a target-dependent module switching the kinase from an off state to an on state. As compared to the allosteric mode of activation, there is no need for the presence of a third partner. None of the ribozymes discovered to date have such a mode of activation, nor does any other known RNA. Starting from a specific on/off adaptor for the hepatitis delta virus ribozyme, that differs but has a mechanism reminiscent of this signalling kinase, we have adapted this mode of activation, using the techniques of molecular engineering, to both catalytic RNAs and DNAs exhibiting various activities. Specifically, we adapted three cleaving ribozymes (hepatitis delta virus, hammerhead and hairpin ribozymes), a cleaving 10-23 deoxyribozyme, a ligating hairpin ribozyme and an artificially selected capping ribozyme. In each case, there was a significant gain in terms of substrate specificity. Even if this mode of control is unreported for natural catalytic nucleic acids, its use needs not be limited to proteinous enzymes. We suggest that the complexity of the modern cellular metabolism might have been an important selective pressure in this evolutionary process

p16 Mutation Spectrum in the Premalignant Condition Barrett's Esophagus

Background: Mutation, promoter hypermethylation and loss of heterozygosity involving the tumor suppressor gene p16 (CDKN2a/INK4a) have been detected in a wide variety of human cancers, but much less is known concerning the frequency and spectrum of p16 mutations in premalignant conditions. Methods and Findings: We have determined the p16 mutation spectrum for a cohort of 304 patients with Barrett’s esophagus, a premalignant condition that predisposes to the development of esophageal adenocarcinoma. Forty seven mutations were detected by sequencing of p16 exon 2 in 44 BE patients (14.5%) with a mutation spectrum consistent with that caused by oxidative damage and chronic inflammation. The percentage of patients with p16 mutations increased with increasing histologic grade. In addition, samples from 3 out of 19 patients (15.8%) who underwent esophagectomy were found to have mutations. Conclusions: The results of this study suggest the environment of the esophagus in BE patients can both generate an