973 research outputs found
Linear and nonlinear optical spectroscopy of a strongly-coupled microdisk-quantum dot system
A fiber taper waveguide is used to perform direct optical spectroscopy of a
microdisk-quantum-dot system, exciting the system through the photonic (light)
channel rather than the excitonic (matter) channel. Strong coupling, the regime
of coherent quantum interactions, is demonstrated through observation of vacuum
Rabi splitting in the transmitted and reflected signals from the cavity. The
fiber coupling method also allows the examination of the system's steady-state
nonlinear properties, where saturation of the cavity-QD response is observed
for less than one intracavity photon.Comment: adjusted references, added minor clarification
Non-resonant dot-cavity coupling and its applications in resonant quantum dot spectroscopy
We present experimental investigations on the non-resonant dot-cavity
coupling of a single quantum dot inside a micro-pillar where the dot has been
resonantly excited in the s-shell, thereby avoiding the generation of
additional charges in the QD and its surrounding. As a direct proof of the pure
single dot-cavity system, strong photon anti-bunching is consistently observed
in the autocorrelation functions of the QD and the mode emission, as well as in
the cross-correlation function between the dot and mode signals. Strong Stokes
and anti-Stokes-like emission is observed for energetic QD-mode detunings of up
to ~100 times the QD linewidth. Furthermore, we demonstrate that non-resonant
dot-cavity coupling can be utilized to directly monitor and study relevant QD
s-shell properties like fine-structure splittings, emission saturation and
power broadening, as well as photon statistics with negligible background
contributions. Our results open a new perspective on the understanding and
implementation of dot-cavity systems for single-photon sources, single and
multiple quantum dot lasers, semiconductor cavity quantum electrodynamics, and
their implementation, e.g. in quantum information technology.Comment: 17 pages, 4 figure
Climbing the Jaynes-Cummings Ladder and Observing its Sqrt(n) Nonlinearity in a Cavity QED System
The already very active field of cavity quantum electrodynamics (QED),
traditionally studied in atomic systems, has recently gained additional
momentum by the advent of experiments with semiconducting and superconducting
systems. In these solid state implementations, novel quantum optics experiments
are enabled by the possibility to engineer many of the characteristic
parameters at will. In cavity QED, the observation of the vacuum Rabi mode
splitting is a hallmark experiment aimed at probing the nature of matter-light
interaction on the level of a single quantum. However, this effect can, at
least in principle, be explained classically as the normal mode splitting of
two coupled linear oscillators. It has been suggested that an observation of
the scaling of the resonant atom-photon coupling strength in the
Jaynes-Cummings energy ladder with the square root of photon number n is
sufficient to prove that the system is quantum mechanical in nature. Here we
report a direct spectroscopic observation of this characteristic quantum
nonlinearity. Measuring the photonic degree of freedom of the coupled system,
our measurements provide unambiguous, long sought for spectroscopic evidence
for the quantum nature of the resonant atom-field interaction in cavity QED. We
explore atom-photon superposition states involving up to two photons, using a
spectroscopic pump and probe technique. The experiments have been performed in
a circuit QED setup, in which ultra strong coupling is realized by the large
dipole coupling strength and the long coherence time of a superconducting qubit
embedded in a high quality on-chip microwave cavity.Comment: ArXiv version of manuscript published in Nature in July 2008, 5
pages, 5 figures, hi-res version at
http://www.finkjohannes.com/SqrtNArxivPreprint.pd
Quantum nature of a strongly-coupled single quantum dot-cavity system
Cavity quantum electrodynamics (QED) studies the interaction between a
quantum emitter and a single radiation-field mode. When an atom is in strong
coupling with a cavity mode1,2, it is possible to realize key quantum
information processing (QIP) tasks, such as controlled coherent coupling and
entanglement of distinguishable quantum systems. Realizing these tasks in the
solid state is clearly desirable, and coupling semiconductor self-assembled
quantum dots (QDs) to monolithic optical cavities is a promising route to this
end. However, validating the efficacy of QDs in QIP applications requires
confirmation of the quantum nature of the QD-cavity system in the strong
coupling regime. Here we find a confirmation by observing quantum correlations
in photoluminescence (PL) from a photonic crystal (PC) nanocavity3-5
interacting with one, and only one, QD located precisely at the cavity electric
field maximum. When off-resonance, photon emission from the cavity mode and QD
excitons is anti-correlated at the level of single quanta, proving that the
mode is driven solely by the QD despite an energy mis-match between cavity and
excitons. When tuned into resonance, the exciton and photon enter the
strong-coupling regime of cavity-QED and the QD lifetime reduces by a factor of
120. The photon stream from the cavity becomes anti-bunched, proving that the
coupled exciton/photon system is in the quantum anharmonic regime. Our
observations unequivocally show that QIP tasks requiring the quantum nonlinear
regime are achievable in the solid state.Comment: 14 pages 4 figure
Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer
INTRODUCTION
Breast cancer remains a significant scientific, clinical and societal challenge. This gap analysis has reviewed and critically assessed enduring issues and new challenges emerging from recent research, and proposes strategies for translating solutions into practice.
METHODS
More than 100 internationally recognised specialist breast cancer scientists, clinicians and healthcare professionals collaborated to address nine thematic areas: genetics, epigenetics and epidemiology; molecular pathology and cell biology; hormonal influences and endocrine therapy; imaging, detection and screening; current/novel therapies and biomarkers; drug resistance; metastasis, angiogenesis, circulating tumour cells, cancer 'stem' cells; risk and prevention; living with and managing breast cancer and its treatment. The groups developed summary papers through an iterative process which, following further appraisal from experts and patients, were melded into this summary account.
RESULTS
The 10 major gaps identified were: (1) understanding the functions and contextual interactions of genetic and epigenetic changes in normal breast development and during malignant transformation; (2) how to implement sustainable lifestyle changes (diet, exercise and weight) and chemopreventive strategies; (3) the need for tailored screening approaches including clinically actionable tests; (4) enhancing knowledge of molecular drivers behind breast cancer subtypes, progression and metastasis; (5) understanding the molecular mechanisms of tumour heterogeneity, dormancy, de novo or acquired resistance and how to target key nodes in these dynamic processes; (6) developing validated markers for chemosensitivity and radiosensitivity; (7) understanding the optimal duration, sequencing and rational combinations of treatment for improved personalised therapy; (8) validating multimodality imaging biomarkers for minimally invasive diagnosis and monitoring of responses in primary and metastatic disease; (9) developing interventions and support to improve the survivorship experience; (10) a continuing need for clinical material for translational research derived from normal breast, blood, primary, relapsed, metastatic and drug-resistant cancers with expert bioinformatics support to maximise its utility. The proposed infrastructural enablers include enhanced resources to support clinically relevant in vitro and in vivo tumour models; improved access to appropriate, fully annotated clinical samples; extended biomarker discovery, validation and standardisation; and facilitated cross-discipline working.
CONCLUSIONS
With resources to conduct further high-quality targeted research focusing on the gaps identified, increased knowledge translating into improved clinical care should be achievable within five years
Light hadron, Charmonium(-like) and Bottomonium(-like) states
Hadron physics represents the study of strongly interacting matter in all its
manifestations and the understanding of its properties and interactions. The
interest on this field has been revitalized by the discovery of new light
hadrons, charmonium- and bottomonium-like states. I review the most recent
experimental results from different experiments.Comment: Presented at Lepton-Photon 2011, Mumbai, India; 21 pages, 18 figures;
add more references; some correctio
Engineering of quantum dot photon sources via electro-elastic fields
The possibility to generate and manipulate non-classical light using the
tools of mature semiconductor technology carries great promise for the
implementation of quantum communication science. This is indeed one of the main
driving forces behind ongoing research on the study of semiconductor quantum
dots. Often referred to as artificial atoms, quantum dots can generate single
and entangled photons on demand and, unlike their natural counterpart, can be
easily integrated into well-established optoelectronic devices. However, the
inherent random nature of the quantum dot growth processes results in a lack of
control of their emission properties. This represents a major roadblock towards
the exploitation of these quantum emitters in the foreseen applications. This
chapter describes a novel class of quantum dot devices that uses the combined
action of strain and electric fields to reshape the emission properties of
single quantum dots. The resulting electro-elastic fields allow for control of
emission and binding energies, charge states, and energy level splittings and
are suitable to correct for the quantum dot structural asymmetries that usually
prevent these semiconductor nanostructures from emitting polarization-entangled
photons. Key experiments in this field are presented and future directions are
discussed.Comment: to appear as a book chapter in a compilation "Engineering the
Atom-Photon Interaction" published by Springer in 2015, edited by A.
Predojevic and M. W. Mitchel
Precision Measurement of the Mass of the h_c(1P1) State of Charmonium
A precision measurement of the mass of the h_c(1P1) state of charmonium has
been made using a sample of 24.5 million psi(2S) events produced in e+e-
annihilation at CESR. The reaction used was psi(2S) -> pi0 h_c, pi0 -> gamma
gamma, h_c -> gamma eta_c, and the reaction products were detected in the
CLEO-c detector.
Data have been analyzed both for the inclusive reaction and for the exclusive
reactions in which eta_c decays are reconstructed in fifteen hadronic decay
channels. Consistent results are obtained in the two analyses. The averaged
results of the present measurements are M(h_c)=3525.28+-0.19 (stat)+-0.12(syst)
MeV, and B(psi(2S) -> pi0 h_c)xB(h_c -> gamma eta_c)= (4.19+-0.32+-0.45)x10^-4.
Using the 3PJ centroid mass, Delta M_hf(1P)= - M(h_c) =
+0.02+-0.19+-0.13 MeV.Comment: 9 pages, available through http://www.lns.cornell.edu/public/CLNS/,
submitted to PR
Precision Measurement of B(D+ -> mu+ nu) and the Pseudoscalar Decay Constant fD+
We measure the branching ratio of the purely leptonic decay of the D+ meson
with unprecedented precision as B(D+ -> mu+ nu) = (3.82 +/- 0.32 +/-
0.09)x10^(-4), using 818/pb of data taken on the psi(3770) resonance with the
CLEO-c detector at the CESR collider. We use this determination to derive a
value for the pseudoscalar decay constant fD+, combining with measurements of
the D+ lifetime and assuming |Vcd| = |Vus|. We find fD+ = (205.8 +/- 8.5 +/-
2.5) MeV. The decay rate asymmetry [B(D+ -> mu+ nu)-B(D- -> mu- nu)]/[B(D+ ->
mu+ nu)+B(D- -> mu- nu)] = 0.08 +/- 0.08, consistent with no CP violation. We
also set 90% confidence level upper limits on B(D+ -> tau+ nu) < 1.2x10^(-3)
and B(D+ -> e+ nu) < 8.8x10^(-6).Comment: 24 pages, 11 figures and 6 tables, v2 replaced some figure vertical
axis scales, v3 corrections from PRD revie
Measurement of the Absolute Branching Fraction of D_s^+ --> tau^+ nu_tau Decay
Using a sample of tagged D_s decays collected near the D^*_s D_s peak
production energy in e+e- collisions with the CLEO-c detector, we study the
leptonic decay D^+_s to tau^+ nu_tau via the decay channel tau^+ to e^+ nu_e
bar{nu}_tau. We measure B(D^+_s to tau^+ nu_tau) = (6.17 +- 0.71 +- 0.34) %,
where the first error is statistical and the second systematic. Combining this
result with our measurements of D^+_s to mu^+ nu_mu and D^+_s to tau^+ nu_tau
(via tau^+ to pi^+ bar{nu}_tau), we determine f_{D_s} = (274 +- 10 +- 5) MeV.Comment: 9 pages, postscript also available through
http://www.lns.cornell.edu/public/CLNS/2007/, revise
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