Movement pattern components and mastery of an object control skill with error-reduced learning

Objectives: This paper reports the effects of error-reduced learning on movement components and mastery of overhand throwing in children with and without intellectual disability. Methods: Secondary data analysis was performed on two samples of children (typically developing, TD; intellectual disability, ID) who practiced overhand throwing in either an error-reduced (ER) or error-strewn (ES) condition. Movement pattern components were assessed using a sub-skill of Test of Gross Motor Development-2. Results: In TD participants, ER learners displayed improved follow-through while ES learners did not. Among children with ID, ER learners displayed greater improvements of hip/shoulder rotation and follow-through, than ES learners. Discriminant function analysis confirmed that changes in these components differentiated learning groups. Greater percentage of ER, compared to ES, participants progressed to mastery. Conclusions: With suppressed errors, the follow-through component of overhand throwing is likely to emerge, particularly in children with inferior abilities, and cognitive limitations. Error-reduced learning facilitates mastery

In vitro evaluation of antibiotics' combinations for empirical therapy of suspected methicillin resistant Staphylococcus aureus severe respiratory infections

<p>Abstract</p> <p>Background</p> <p>Methicillin resistant <it>Staphylococcus aureus </it>(MRSA) is an increasingly common cause of nosocomial infections, causing severe morbidity and mortality worldwide, and accounting in some hospitals for more than 50% of all <it>S. aureus </it>diseases. Treatment of infections caused by resistant bacterial pathogens mainly relies on two therapeutic modalities: development of new antimicrobials and use of combinations of available antibiotics.</p> <p>Combinations of antibiotics used in the empiric treatment of infections with suspected methicillin resistant <it>Staphylococcus aureus </it>etiology were investigated.</p> <p>Methods</p> <p>Double (vancomycin or teicoplanin with either levofloxacin or cefotaxime) and triple (vancomycin or teicoplanin + levofloxacin + one among amikacin, ceftazidime, cefepime, imipenem, piperacillin/tazobactam) combinations were evaluated by means of checkerboard assay and time kill curves. Mutational rates of single and combined drugs at antimicrobial concentrations equal to the resistance breakpoints were also calculated.</p> <p>Results</p> <p>Vancomycin or teicoplanin + levofloxacin showed synergy in 16/50 and in 9/50 strains respectively, while vancomycin or teicoplanin + cefotaxime resulted synergic for 43/50 and 23/50 strains, respectively. Triple combinations, involving teicoplanin, levofloxacin and ceftazidime or piperacillin/tazobactam gave synergy in 20/25 strains. Teicoplanin + levofloxacin gave synergy in triple combinations more frequently than vancomycin + levofloxacin.</p> <p>For single antibiotics, mutational frequencies ranged between 10^-5and <10^-9for levofloxacin, cefotaxime, amikacin and imipenem, and <10^-9for vancomycin and teicoplanin. When tested in combinations, mutational frequencies fell below 10^-9for all the combinations.</p> <p>Conclusion</p> <p><it>In vitro </it>evidence of synergy between glycopeptides, fluoroquinolones (levofloxacin) and β-lactams and of reduction of mutational frequencies by combinations are suggestive for a potential role in empirical therapy of severe pneumonia with suspected MRSA etiology.</p

Reduction of errors during practice facilitates fundamental movement skill learning in children with intellectual disabilities

Background Children with intellectual disabilities (ID) have been found to have inferior motor proficiencies in fundamental movement skills (FMS). This study examined the effects of training the FMS of overhand throwing by manipulating the amount of practice errors. Methods Participants included 39 children with ID aged 4-11 years who were allocated into either an error-reduced (ER) training programme or a more typical programme in which errors were frequent (error-strewn, ES). Throwing movement form, throwing accuracy, and throwing frequency during free play were evaluated. Results The ER programme improved movement form, and increased throwing activity during free play to a greater extent than the ES programme. Furthermore, ER learners were found to be capable of engaging in a secondary cognitive task while manifesting robust throwing accuracy performance. Conclusions The findings support the use of movement skills training programmes that constrain practice errors in children with ID, suggesting that such approach results in improved performance and heightened movement engagement in free play. © 2012 The Authors. Journal of Intellectual Disability Research © 2012 Blackwell Publishing Ltd.link_to_subscribed_fulltex

Reduced errors in overhand throwing practice of children with and without disability: analysis of movement components

Poster Displays Saturday Session - Paediatrics (PO-38-Sat2): no. RR-PO-17-24-Sat.The Conference program's website is located at http://www.wcpt.org/sites/wcpt.org/files/files/wpt15/WCPT2015_Programme_FINAL_lores.pd

Safety, Ergonomics and Human Factors in Reconfigurable Manufacturing Systems

In the recent years, the adoption of reconfigurable systems represents a primary strategy to improving flexibility, elasticity and efficiency in both manufacturing and assembly. Global markets, the increasing need for customization, high quality standards, dynamic batches and short life cycles are the key factors driving the transition from traditional to reconfigurable manufacturing systems (RMSs). Despite their automation level, such systems still require actions by human operators, e.g. material handling, WIP load/unload, tool setup, etc. These operations rise safety issues because of the human–machine interaction and cooperation. Particularly, RMSs require changes of auxiliary modules and tools, based on the manual intervention, to achieve effective system configurations enlarging the produced mix. In this field, embracing the emerging Industry 4.0 technology, a lack of procedures and reference approaches exists to supporting companies and practitioners in analysing the impact on safety and ergonomics coming from the switch from standard to RMSs. This chapter, after revising the literature, standards and reference guidelines, converges to an innovative methodological and operative framework supporting and spreading the integration of safety, ergonomics and human factors in the emerging reconfigurable systems. Deep attention is paid to best-in-class examples, from industry, to strengthen the industrial perspective and applicability