423 research outputs found
Dynamic interfacial trapping of flexural waves in structured plates
The paper presents new results on the localization and transmission of flexural waves in a structured plate containing a semi-infinite two-dimensional array of rigid pins. In particular, localized waves are identified and studied at the interface boundary between the homogeneous part of the flexural plate and the part occupied by rigid pins. A formal connection has been made with the dispersion properties of flexural Bloch waves in an infinite doubly periodic array of rigid pins. Special attention is given to regimes corresponding to standing waves of different types as well as Dirac-like points that may occur on the dispersion surfaces. A single half-grating problem, hitherto unreported in the literature, is also shown to bring interesting solutions
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Underwriting Apophenia and Cryptids: Are Cycles Statistical Figments of our Imagination?
This paper re-examines the evidence in favour of the existence of underwriting cycles in property and casualty insurance and their economical significance. Using a meta-analysis of published papers in the area of insurance economics, we show that the evidence supporting the existence of underwriting cycles is misleading. There is, in fact, little evidence in favour of insurance cycles with a linear autoregressive character. This means that any cyclicality in firm profitability in the property and casualty insurance industry is not predictable in a classical econometric framework. It follows that pricing in the property and casualty insurance industry is not incompatible with that of a competitive market
Comparison of the Full Outline of UnResponsiveness and Glasgow Liege Scale/Glasgow Coma Scale in an Intensive Care Unit Population.
peer reviewedBACKGROUND: The Full Outline of UnResponsiveness (FOUR) has been proposed as an alternative for the Glasgow Coma Scale (GCS)/Glasgow Liege Scale (GLS) in the evaluation of consciousness in severely brain-damaged patients. We compared the FOUR and GLS/GCS in intensive care unit patients who were admitted in a comatose state. METHODS: FOUR and GLS evaluations were performed in randomized order in 176 acutely (<1 month) brain-damaged patients. GLS scores were transformed in GCS scores by removing the GLS brainstem component. Inter-rater agreement was assessed in 20% of the studied population (N = 35). A logistic regression analysis adjusted for age, and etiology was performed to assess the link between the studied scores and the outcome 3 months after injury (N = 136). RESULTS: GLS/GCS verbal component was scored 1 in 146 patients, among these 131 were intubated. We found that the inter-rater reliability was good for the FOUR score, the GLS/GCS. FOUR, GLS/GCS total scores predicted functional outcome with and without adjustment for age and etiology. 71 patients were considered as being in a vegetative/unresponsive state based on the GLS/GCS. The FOUR score identified 8 of these 71 patients as being minimally conscious given that these patients showed visual pursuit. CONCLUSIONS: The FOUR score is a valid tool with good inter-rater reliability that is comparable to the GLS/GCS in predicting outcome. It offers the advantage to be performable in intubated patients and to identify non-verbal signs of consciousness by assessing visual pursuit, and hence minimal signs of consciousness (11% in this study), not assessed by GLS/GCS scales
Formalization of Transform Methods using HOL Light
Transform methods, like Laplace and Fourier, are frequently used for
analyzing the dynamical behaviour of engineering and physical systems, based on
their transfer function, and frequency response or the solutions of their
corresponding differential equations. In this paper, we present an ongoing
project, which focuses on the higher-order logic formalization of transform
methods using HOL Light theorem prover. In particular, we present the
motivation of the formalization, which is followed by the related work. Next,
we present the task completed so far while highlighting some of the challenges
faced during the formalization. Finally, we present a roadmap to achieve our
objectives, the current status and the future goals for this project.Comment: 15 Pages, CICM 201
Thermodynamic analysis of black hole solutions in gravitating nonlinear electrodynamics
We perform a general study of the thermodynamic properties of static
electrically charged black hole solutions of nonlinear electrodynamics
minimally coupled to gravitation in three space dimensions. The Lagrangian
densities governing the dynamics of these models in flat space are defined as
arbitrary functions of the gauge field invariants, constrained by some
requirements for physical admissibility. The exhaustive classification of these
theories in flat space, in terms of the behaviour of the Lagrangian densities
in vacuum and on the boundary of their domain of definition, defines twelve
families of admissible models. When these models are coupled to gravity, the
flat space classification leads to a complete characterization of the
associated sets of gravitating electrostatic spherically symmetric solutions by
their central and asymptotic behaviours. We focus on nine of these families,
which support asymptotically Schwarzschild-like black hole configurations, for
which the thermodynamic analysis is possible and pertinent. In this way, the
thermodynamic laws are extended to the sets of black hole solutions of these
families, for which the generic behaviours of the relevant state variables are
classified and thoroughly analyzed in terms of the aforementioned boundary
properties of the Lagrangians. Moreover, we find universal scaling laws (which
hold and are the same for all the black hole solutions of models belonging to
any of the nine families) running the thermodynamic variables with the electric
charge and the horizon radius. These scale transformations form a one-parameter
multiplicative group, leading to universal "renormalization group"-like
first-order differential equations. The beams of characteristics of these
equations generate the full set of black hole states associated to any of these
gravitating nonlinear electrodynamics...Comment: 51 single column pages, 19 postscript figures, 2 tables, GRG tex
style; minor corrections added; final version appearing in General Relativity
and Gravitatio
Liquid-infiltrated photonic crystals - enhanced light-matter interactions for lab-on-a-chip applications
Optical techniques are finding widespread use in analytical chemistry for
chemical and bio-chemical analysis. During the past decade, there has been an
increasing emphasis on miniaturization of chemical analysis systems and
naturally this has stimulated a large effort in integrating microfluidics and
optics in lab-on-a-chip microsystems. This development is partly defining the
emerging field of optofluidics. Scaling analysis and experiments have
demonstrated the advantage of micro-scale devices over their macroscopic
counterparts for a number of chemical applications. However, from an optical
point of view, miniaturized devices suffer dramatically from the reduced
optical path compared to macroscale experiments, e.g. in a cuvette. Obviously,
the reduced optical path complicates the application of optical techniques in
lab-on-a-chip systems. In this paper we theoretically discuss how a strongly
dispersive photonic crystal environment may be used to enhance the light-matter
interactions, thus potentially compensating for the reduced optical path in
lab-on-a-chip systems. Combining electromagnetic perturbation theory with
full-wave electromagnetic simulations we address the prospects for achieving
slow-light enhancement of Beer-Lambert-Bouguer absorption, photonic band-gap
based refractometry, and high-Q cavity sensing.Comment: Invited paper accepted for the "Optofluidics" special issue to appear
in Microfluidics and Nanofluidics (ed. Prof. David Erickson). 11 pages
including 8 figure
Combining Feature Selection and Integration—A Neural Model for MT Motion Selectivity
Background: The computation of pattern motion in visual area MT based on motion input from area V1 has been investigated in many experiments and models attempting to replicate the main mechanisms. Two different core conceptual approaches were developed to explain the findings. In integrationist models the key mechanism to achieve pattern selectivity is the nonlinear integration of V1 motion activity. In contrast, selectionist models focus on the motion computation at positions with 2D features. Methodology/Principal Findings: Recent experiments revealed that neither of the two concepts alone is sufficient to explain all experimental data and that most of the existing models cannot account for the complex behaviour found. MT pattern selectivity changes over time for stimuli like type II plaids from vector average to the direction computed with an intersection of constraint rule or by feature tracking. Also, the spatial arrangement of the stimulus within the receptive field of a MT cell plays a crucial role. We propose a recurrent neural model showing how feature integration and selection can be combined into one common architecture to explain these findings. The key features of the model are the computation of 1D and 2D motion in model area V1 subpopulations that are integrated in model MT cells using feedforward and feedback processing. Our results are also in line with findings concerning the solution of the aperture problem. Conclusions/Significance: We propose a new neural model for MT pattern computation and motion disambiguation that i
Application of the PM6 method to modeling the solid state
The applicability of the recently developed PM6 method for modeling various properties of a wide range of organic and inorganic crystalline solids has been investigated. Although the geometries of most systems examined were reproduced with good accuracy, severe errors were found in the predicted structures of a small number of solids. The origin of these errors was investigated, and a strategy for improving the method proposed
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