Assessing the feasibility of adaptation options: methodological advancements and directions for climate adaptation research and practice

The Paris Agreement put adaptation prominently on the global climate action agenda. Despite a surge in research and praxis-based knowledge on adaptation, a critical policy roadblock is synthesizing and assessing this burgeoning evidence. We develop an approach to assess the multidimensional feasibility of adaptation options in a robust and transparent manner, providing direction for global climate policy and identifying knowledge gaps to further future climate research. The approach, which was tested in the IPCC Special Report on 1.5 °C (SR1.5) to assess 23 adaptation options, is underpinned by a systematic review of recent literature, expert elicitation, and iterative peer review. It responds to the challenge of limited agreement on adaptation indicators, lack of fine-scale adaptation data, and challenges of assessing synergies and trade-offs with mitigation. The findings offer methodological insights into how future assessments such as the IPCC Assessment Report (AR) six and regional, national, and sectoral assessment exercises could assess adaptation feasibility and synthesize the growing body of knowledge on climate change adaptation

Platinum compounds and sodium metabolism in children with diencephalic glioma

In this brief report we have described eight children affected by optic pathway/hypothalamus gliomas and treated with carboplatin and/or cisplatin, which developed a derangement of sodium and water metabolism, due to diabetes insipidus (DI) or to syndrome of inappropriate antidiuretic hormone secretion (SIADH) after surgical resection. In four out of these eight patients the treatment with platinum compounds produced prolonged haematological toxicity and in five out of them it caused neurosensorial bilateral hypoacusia. In addition cisplatin worsened electrolytes disturbances. Hence children with DI or SIADH should be carefully monitored before, during and after the treatment with platinum compounds

Spatial Narratives in Museums and Online : The Birth of the Digital Object Itinerary

Museums represent complex layers of place. From carefully managed curatorial spaces, to exhibition environments, to the layout of display cases, to the representation of distant parts embodied in the collections of the great encyclopedic collections, the negotiation, representation and presentation of place has always been central to the mission of any museum. This chapter will examine the history of how museums (especially museum catalogues) present place, from early origins to the Internet. A set of case studies will be examined as a means of exploring how, where and in what form art objects and artefacts first began to be transported from non-Western to Western nations for display in the museums of Western capitals, thus representing the origins of what Cuno has called our “basic and inevitable cultural interrelatedness”; and what others have called “object itineraries” or “object biographies”. A comparison will be made of the same museums’ online representation of the same places today. It will thus be possible to present a framework for considering object itineraries – historic and modern - as a subject of both history and historiography.ancient itineraries, funded by the Getty Foundatio