24,758 research outputs found

    Evolutionary game of coalition building under external pressure

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    We study the fragmentation-coagulation (or merging and splitting) evolutionary control model as introduced recently by one of the authors, where NN small players can form coalitions to resist to the pressure exerted by the principal. It is a Markov chain in continuous time and the players have a common reward to optimize. We study the behavior as NN grows and show that the problem converges to a (one player) deterministic optimization problem in continuous time, in the infinite dimensional state space

    Climate and soil moisture content during development ofthe frst palaeosol in the southern Loess Plateau

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    The scientific problems concerning Quaternary soil water content and the water cycle have not been researched. This study examined the soil water content and depth of distribution of gravitational water in the south Loess Plateau during development of the first palaeosol layer (S1) by methods such as field investigation, electron microscopy, energy spectrum analysis, chemical analysis, and so on. The purpose was to reveal the climate, water balance and vegetation type at the time when S1 developed. The depth of migration of CaCO3 and Sr were 4.2 m below the upper boundary of the S1 palaeosol, and the depth of weathered loess beneath the argillic horizon was 4.0 m. Ferri‐argillans developed well in the argillic horizon and their depth of migration was 1 m below the argillic horizon. These findings suggest that the climate during the last interglacial was subtropical and humid, and the soil‐water balance was positive. Gravitational water was present to a depth of least 4.2 m from the top of S1, and the water content was adequate for tree growth. The chemical weathering index showed that this palaeosol has been moderately weathered

    Multiple Ca2+ signaling pathways regulate intracellular Ca 2+ activity in human cardiac fibroblasts

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    Ca2+ signaling pathways are well studied in cardiac myocytes, but not in cardiac fibroblasts. The aim of the present study is to characterize Ca2+ signaling pathways in cultured human cardiac fibroblasts using confocal scanning microscope and RT-PCR techniques. It was found that spontaneous intracellular Ca2+ (Cai 2+) oscillations were present in about 29% of human cardiac fibroblasts, and the number of cells with Cai 2+ oscillations was increased to 57.3% by application of 3% fetal bovine serum. Cai 2+ oscillations were dependent on Ca2+ entry. Cai2+ oscillations were abolished by the store-operated Ca2+ (SOC) entry channel blocker La3+, the phospholipase C inhibitor U-73122, and the inositol trisphosphate receptors (IP3Rs) inhibitor 2-aminoethoxydiphenyl borate, but not by ryanodine. The IP3R agonist thimerosal enhanced Ca2+ i oscillations. Inhibition of plasma membrane Ca2+ pump (PMCA) and Na+-Ca2+ exchanger (NCX) also suppressed Ca i 2+ oscillations. In addition, the frequency of Ca i 2+ oscillations was reduced by nifedipine, and increased by Bay K8644 in cells with spontaneous Cai 2+ oscillations. RT-PCR revealed that mRNAs for IP3R1-3, SERCA1-3, CaV1.2, NCX3, PMCA1,3,4, TRPC1,3,4,6, STIM1, and Orai1-3, were readily detectable, but not RyRs. Our results demonstrate for the first time that spontaneous Cai 2+ oscillations are present in cultured human cardiac fibroblasts and are regulated by multiple Ca2+ pathways, which are not identical to those of the well-studied contractile cardiomyocytes. This study provides a base for future investigations into how Ca2+ signals regulate biological activity in human cardiac fibroblasts and cardiac remodeling under pathological conditions. © 2009 Wiley-Liss, Inc.postprin

    Anomaly and a QCD-like phase diagram with massive bosonic baryons

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    We study a strongly coupled Z2Z_2 lattice gauge theory with two flavors of quarks, invariant under an exact SU(2)×SU(2)×UA(1)×UB(1)\mathrm{SU}(2)\times \mathrm{SU}(2) \times \mathrm{U}_A(1) \times \mathrm{U}_B(1) symmetry which is the same as QCD with two flavors of quarks without an anomaly. The model also contains a coupling that can be used to break the UA(1)\mathrm{U}_A(1) symmetry and thus mimic the QCD anomaly. At low temperatures TT and small baryon chemical potential μB\mu_B the model contains massless pions and massive bosonic baryons similar to QCD with an even number of colors. In this work we study the TμBT-\mu_B phase diagram of the model and show that it contains three phases : (1) A chirally broken phase at low TT and μB\mu_B, (2) a chirally symmetric baryon superfluid phase at low TT and high μB\mu_B, and (3) a symmetric phase at high TT. We find that the nature of the finite temperature chiral phase transition and in particular the location of the tricritical point that seperates the first order line from the second order line is affected significantly by the anomaly.Comment: 22 pages, 16 figures, 5 tables, references adde

    An invisibility cloak using silver nanowires

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    In this paper, we use the parameter retrieval method together with an analytical effective medium approach to design a well-performed invisible cloak, which is based on an empirical revised version of the reduced cloak. The designed cloak can be implemented by silver nanowires with elliptical cross-sections embedded in a polymethyl methacrylate host. This cloak is numerically proved to be robust for both the inner hidden object as well as incoming detecting waves, and is much simpler thus easier to manufacture when compared with the earlier proposed one [Nat. Photon. 1, 224 (2007)].Comment: 7 pages, 4 figures, 2 table
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