983 research outputs found
Use of remotely-derived bathymetry for modelling biomass in marine environments
The paper presents results on the influence of geometric attributes of satellite-derived raster bathymetric data, namely the General Bathymetric Charts of the Oceans, on spatial statistical modelling of marine biomass. In the initial experiment, both the resolution and projection of the raster dataset are taken into account. It was found that, independently of the equal-area projection chosen for the analysis, the calculated areas are very similar, and the differences between them are insignificant. Likewise, any variation in the raster resolution did not change the computed area. Although the differences were shown to be insignificant, for the subsequent analysis we selected the cylindrical equal area projection, as it implies rectangular spatial extent, along with the automatically derived resolution. Then, in the second experiment, we focused on demersal fish biomass data acquired from trawl samples taken from the western parts of ICES Sub-area VII, near the sea floor. The aforementioned investigation into processing bathymetric data allowed us to build various statistical models that account for a relationship between biomass, sea floor topography and geographic location. We fitted a set of generalised additive models and generalised additive mixed models to combinations of trawl data of the roundnose grenadier (Coryphaenoides rupestris) and bathymetry. Using standard statistical techniques—such as analysis of variance, Akaike information criterion, root mean squared error, mean absolute error and cross-validation—we compared the performance of the models and found that depth and latitude may serve as statistically significant explanatory variables for biomass of roundnose grenadier in the study area. However, the results should be interpreted with caution as sampling locations may have an impact on the biomass–depth relationship
Kinetic Predictions Concerning the Long-Term Stability of TKX-50 and Other Common Explosives Using the NETZSCH Kinetics Neo Software
Explosives are used in both military and civilian applications all over the world. Sufficient longevity and good thermal stability are therefore essential for safe handling and safe storage of energetic materials. In this work, five well-known compounds, TKX-50, RDX, HMX, CL-20 and PETN, were investigated by means of different kinetic models, in order to make predictions about their long-term stability. For this purpose, the compounds were synthesized according to literature-known procedures and thermogravimetric (TG) measurements were performed. The TG plots were analyzed using the Ozawa-Flynn-Wall, Friedman and ASTM E698 kinetic models with the NETZSCH Kinetics Neo software and the activation energy and isothermal long-term stability were determined. Moreover, various climatic predictions of different countries were made
Natural supramolecular protein assemblies
Supramolecular protein assemblies are an emerging area within the chemical sciences, which combine the topological structures of the field of supramolecular chemistry and the state-of-the-art chemical biology approaches to unravel the formation and function of protein assemblies. Recent chemical and biological studies on natural multimeric protein structures, including fibers, rings, tubes, catenanes, knots, and cages, have shown that the quaternary structures of proteins are a prerequisite for their highly specific biological functions. In this review, we illustrate that a striking structural diversity of protein assemblies is present in nature. Furthermore, we describe structure–function relationship studies for selected classes of protein architectures, and we highlight the techniques that enable the characterisation of supramolecular protein structures
Impact of Pacific white shrimp culture on wild population of Tiger shrimp in Andhra Pradesh
Andhra Pradesh is the leading producer of shrimp
through aquaculture in India where production was
279727 t in 2014-2015 (MPEDA). The bulk of it
(276077 t) came from the Pacific white shrimp,
Litopenaeus vannamei production. This species is a
relative new comer to the aquaculture scenario of
Andhra Pradesh with official recorded production
starting from 2009 onwards
Characterization and Optimization of a Conical Corona Reactor for Seed Treatment of Rapeseed
Plasma agriculture is a growing field that combines interdisciplinary areas with the aim of researching alternative solutions for increasing food production. In this field, plasma sources are used for the treatment of different agricultural goods in pre-and post-harvest. With the big variety of possible treatment targets, studied reactors must be carefully investigated and characterized for specific goals. Therefore, in the present study, a cone-shaped corona reactor working with argon was adapted for the treatment of small seeds, and its basic properties were investigated. The treatment of rapeseed using different voltage duty cycles led to an increase in surface wettability, possibly contributing to the accelerated germination (27% for 90% duty cycle). The discharge produced by the conical reactor was able to provide an environment abundant with reactive oxygen species that makes the process suitable for seeds treatment. However, operating in direct treatment configuration, large numbers of seeds placed in the reactor start impairing the discharge homogeneity
Lithium‐ion mobility in Li6B18(Li3N) and Li vacancy tuning in the solid solution Li6B18(Li3N)1−x(Li2O)x
All-solid-state batteries are promising candidates for safe energy-storage systems due to non-flammable solid electrolytes and the possibility to use metallic lithium as an anode. Thus, there is a challenge to design new solid electrolytes and to understand the principles of ion conduction on an atomic scale. We report on a new concept for compounds with high lithium ion mobility based on a rigid open-framework boron structure. The host–guest structure Li6B18(Li3N) comprises large hexagonal pores filled with urn:x-wiley:14337851:media:anie202213962:anie202213962-math-0001 Li7N] strands that represent a perfect cutout from the structure of α-Li3N. Variable-temperature 7Li NMR spectroscopy reveals a very high Li mobility in the template phase with a remarkably low activation energy below 19 kJ mol−1 and thus much lower than pristine Li3N. The formation of the solid solution of Li6B18(Li3N) and Li6B18(Li2O) over the complete compositional range allows the tuning of lithium defects in the template structure that is not possible for pristine Li3N and Li2O
On the experimental verification of quantum complexity in linear optics
The first quantum technologies to solve computational problems that are
beyond the capabilities of classical computers are likely to be devices that
exploit characteristics inherent to a particular physical system, to tackle a
bespoke problem suited to those characteristics. Evidence implies that the
detection of ensembles of photons, which have propagated through a linear
optical circuit, is equivalent to sampling from a probability distribution that
is intractable to classical simulation. However, it is probable that the
complexity of this type of sampling problem means that its solution is
classically unverifiable within a feasible number of trials, and the task of
establishing correct operation becomes one of gathering sufficiently convincing
circumstantial evidence. Here, we develop scalable methods to experimentally
establish correct operation for this class of sampling algorithm, which we
implement with two different types of optical circuits for 3, 4, and 5 photons,
on Hilbert spaces of up to 50,000 dimensions. With only a small number of
trials, we establish a confidence >99% that we are not sampling from a uniform
distribution or a classical distribution, and we demonstrate a unitary specific
witness that functions robustly for small amounts of data. Like the algorithmic
operations they endorse, our methods exploit the characteristics native to the
quantum system in question. Here we observe and make an application of a
"bosonic clouding" phenomenon, interesting in its own right, where photons are
found in local groups of modes superposed across two locations. Our broad
approach is likely to be practical for all architectures for quantum
technologies where formal verification methods for quantum algorithms are
either intractable or unknown.Comment: Comments welcom
Cul3 regulates cytoskeleton protein homeostasis and cell migration during a critical window of brain development
De novo loss of function mutations in the ubiquitin ligase-encoding gene Cullin3 (CUL3) lead to autism spectrum disorder (ASD). Here, we used Cul3 mouse models to evaluate the consequences of Cul3 mutations in vivo. Our results show that Cul3 haploinsufficient mice exhibit deficits in motor coordination as well as ASD-relevant social and cognitive impairments. Cul3 mutant brain displays cortical lamination abnormalities due to defective neuronal migration and reduced numbers of excitatory and inhibitory neurons. In line with the observed abnormal columnar organization, Cul3 haploinsufficiency is associated with decreased spontaneous excitatory and inhibitory activity in the cortex. At the molecular level, employing a quantitative proteomic approach, we show that Cul3 regulates cytoskeletal and adhesion protein abundance in mouse embryos. Abnormal regulation of cytoskeletal proteins in Cul3 mutant neuronal cells results in atypical organization of the actin mesh at the cell leading edge, likely causing the observed migration deficits. In contrast to these important functions early in development, Cul3 deficiency appears less relevant at adult stages. In fact, induction of Cul3 haploinsufficiency in adult mice does not result in the behavioral defects observed in constitutive Cul3 haploinsufficient animals. Taken together, our data indicate that Cul3 has a critical role in the regulation of cytoskeletal proteins and neuronal migration and that ASD-associated defects and behavioral abnormalities are primarily due to Cul3 functions at early developmental stages
Mechanism of biomolecular recognition of trimethyllysine by the fluorinated aromatic cage of KDM5A PHD3 finger
The understanding of biomolecular recognition of posttranslationally modified histone proteins is centrally important to the histone code hypothesis. Despite extensive binding and structural studies on the readout of histones, the molecular language by which posttranslational modifications on histone proteins are read remains poorly understood. Here we report physical-organic chemistry studies on the recognition of the positively charged trimethyllysine by the electron-rich aromatic cage containing PHD3 finger of KDM5A. The aromatic character of two tryptophan residues that solely constitute the aromatic cage of KDM5A was fine-tuned by the incorporation of fluorine substituents. Our thermodynamic analyses reveal that the wild-type and fluorinated KDM5A PHD3 fingers associate equally well with trimethyllysine. This work demonstrates that the biomolecular recognition of trimethyllysine by fluorinated aromatic cages is associated with weaker cation-π interactions that are compensated by the energetically more favourable trimethyllysine-mediated release of high-energy water molecules that occupy the aromatic cage
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