Child survival in a rural area in Zimbabwe: are we winning?

A research paper on efforts and programmes initiated to promote child health in rural Zimbabwe.Health teams in a rural district in Zimbabwe have been implementing child survival programmes since 1984. A prospective study of the causes of morbidity and mortality in under-five children was done. Community based surveys assessing nutrition status, immunization coverage and knowledge and use of sugar and salt solution for diarrhoea were carried out. Malnutrition, acute respiratory infections and diarrnoea accounted for 69,7 pc of the 902 undcr-fives admissions while 33 (67,4 pc) of the hospital deaths were undcr-fives. The mortality pattern parallelled that of morbidity. Malnutrition was more common in the dry communal areas and on the commercial estates. Full immunization coverage rates in the 12 23-monih-olds increased from 44,3 pc in 1984 to 70 pc in 1989; and up to 69 pc of the mothers correctly prepared and used sugar and salt solution for diarrhoea management. Although there appears to have been little impact on malnutrition, respiratory infections and diarrhoea, the study shows that a lot can be achieved even in a remote rural district given political will, community involvement, and dedicated staff

A method for evaluating the mechanical performance of thin-walled titanium tubes

A method which was developed to compare the stress-strain properties of three types of thin-walled, commercially pure titanium tubes is presented. The tubes were of types intended for use in large heat-exchanger applications and were to be subjected to significant plastic deformation during subsequent assembly processes. It had been anticipated that small differences in chemical composition and tube-drawing treatment would produce quite different characteristics. It is known that the properties of titanium can exhibit considerable degrees of anisotropy, especially for wrought products; although axial properties of the materials could be evaluated using standard test equipment and procedures, a novel testing system had to be designed to allow the circumferential properties to be assessed. Significant differences between tube types were observed and anisotropic material behaviour was apparent

Gaussian limits for multidimensional random sequential packing at saturation (extended version)

Consider the random sequential packing model with infinite input and in any dimension. When the input consists of non-zero volume convex solids we show that the total number of solids accepted over cubes of volume $\lambda$ is asymptotically normal as $\lambda \to \infty$. We provide a rate of approximation to the normal and show that the finite dimensional distributions of the packing measures converge to those of a mean zero generalized Gaussian field. The method of proof involves showing that the collection of accepted solids satisfies the weak spatial dependence condition known as stabilization.Comment: 31 page

H-dibaryons and Primordial Nucleosynthesis

The apparent discrepancy between abundances of light nuclides predicted by the standard Big-Bang and observational data is explained, by assuming the presence of metastable H dibaryons at the nucleosynthesis era. These dibaryons could be formed out of a small fraction of strange quarks at the moment of the confinement transition. For a primordial deuterium abundance of the order of 3 10^{-5}, the measured differences in the 4He abundances requires a relative abundance of H dibaryons of the order of n_H/n_B = 0.07, decaying in a timescale of the order of 10^5 s.Comment: Latex, 5 pages, to appear in PR

Adsorption of Line Segments on a Square Lattice

We study the deposition of line segments on a two-dimensional square lattice. The estimates for the coverage at jamming obtained by Monte-Carlo simulations and by $7^{th}$-order time-series expansion are successfully compared. The non-trivial limit of adsorption of infinitely long segments is studied, and the lattice coverage is consistently obtained using these two approaches.Comment: 19 pages in Latex+5 postscript files sent upon request ; PTB93_

Bortezomib maintenance after R-CHOP, cytarabine and autologous stem cell transplantation in newly diagnosed patients with mantle cell lymphoma, results of a randomised phase II HOVON trial

Rituximab-containing induction followed by autologous stem cell transplantation (ASCT) is the standard first-line treatment for young mantle cell lymphoma patients. However, most patients relapse after ASCT. We investigated in a randomised phase II study the outcome of a chemo-immuno regimen and ASCT with or without maintenance therapy with bortezomib. Induction consisted of three cycles R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, prednisone), two cycles high-dose cytarabine, BEAM (carmustine, etoposide, cytarabine, melphalan) and ASCT. Patients responding were randomised between bortezomib maintenance (1·3 mg/m2 intravenously once every 2 weeks, for 2 years) and observation. Of 135 eligible patients, 115 (85%) proceeded to ASCT, 60 (44%) were randomised. With a median follow-up of 77·5 months for patients still alive, 5-year event-free survival (EFS) was 51% (95% CI 42–59%); 5-year overall survival (OS) was 73% (95% CI 65–80%). The median follow-up of randomised patients still alive was 71·5 months. Patients with bortezomib maintenance had a 5-year EFS of 63% (95% CI 44–78%) and 5-year OS of 90% (95% CI 72–97%). The patients randomised to observation had 5-year PFS of 60% (95% CI, 40–75%) and OS of 90% (95% CI 72–97%). In conclusion, in this phase II study we found no indication of a positive effect of bortezomib maintenance after ASCT

On the mechanisms governing gas penetration into a tokamak plasma during a massive gas injection

A new 1D radial fluid code, IMAGINE, is used to simulate the penetration of gas into a tokamak plasma during a massive gas injection (MGI). The main result is that the gas is in general strongly braked as it reaches the plasma, due to mechanisms related to charge exchange and (to a smaller extent) recombination. As a result, only a fraction of the gas penetrates into the plasma. Also, a shock wave is created in the gas which propagates away from the plasma, braking and compressing the incoming gas. Simulation results are quantitatively consistent, at least in terms of orders of magnitude, with experimental data for a D 2 MGI into a JET Ohmic plasma. Simulations of MGI into the background plasma surrounding a runaway electron beam show that if the background electron density is too high, the gas may not penetrate, suggesting a possible explanation for the recent results of Reux et al in JET (2015 Nucl. Fusion 55 093013)

Velocity-space sensitivity of the time-of-flight neutron spectrometer at JET

The velocity-space sensitivities of fast-ion diagnostics are often described by so-called weight functions. Recently, we formulated weight functions showing the velocity-space sensitivity of the often dominant beam-target part of neutron energy spectra. These weight functions for neutron emission spectrometry (NES) are independent of the particular NES diagnostic. Here we apply these NES weight functions to the time-of-flight spectrometer TOFOR at JET. By taking the instrumental response function of TOFOR into account, we calculate time-of-flight NES weight functions that enable us to directly determine the velocity-space sensitivity of a given part of a measured time-of-flight spectrum from TOFOR

Track A Basic Science

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/138319/1/jia218438.pd