Proton Stripping to Stretched States in 26-Al, 52-Cr, and 60-Si

This research was sponsored by the National Science Foundation Grant NSF PHy 87-1440

Spectroscopy of A=12 at High Excitation

Supported by the National Science Foundation and Indiana Universit

Nonlinear Mixed-Effect Pharmacokinetic Modeling and Distribution of Doxycycline in Healthy Female Donkeys after Multiple Intragastric Dosing–Preliminary Investigation

Doxycycline (DXC) is a broad-spectrum antibacterial antimicrobial administered to horses for the treatment of bacterial infections which may also affect donkeys. Donkeys have a different metabolism than horses, leading to differences in the pharmacokinetics of drugs compared to horses. This study aimed to describe the population pharmacokinetics of DXC in donkeys. Five doses of DXC hyclate (10 mg/kg) were administered via a nasogastric tube, q12 h, to eight non-fasted, healthy, adult jennies. Serum, urine, synovial fluid and endometrium were collected for 72 h following the first administration. Doxycycline concentration was measured by competitive enzyme immunoassay. Serum concentrations versus time data were fitted simultaneously using the stochastic approximation expectation-maximization algorithm for nonlinear mixed effects. A one-compartment model with linear elimination and first-order absorption after intragastric administration, best described the available pharmacokinetic data. Final parameter estimates indicate that DXC has a high volume of distribution (108 L/kg) as well as high absorption (10.3 h-1) in donkeys. However, results suggest that oral DXC at 10 mg/kg q12 h in donkeys would not result in a therapeutic concentration in serum, urine, synovial fluid or endometrium by comparison to the minimum inhibitory concentration of common equine pathogens. Further studies are recommended to identify appropriate dosage and dosing intervals of oral DXC in donkeys

Economic Analysis of Using Mixing Equipment for Growing Heifers

Seventy-two Simmental cross and Charolais cross heifers (475 lb.) were utilized in a growing study to estimate the economic value of using a mixer wagon and feed scale to feed light cattle a high roughage diet. Cattle fed the mixed diet gained an additional 22.6 lb. on 61.2 lb. less dry matter over the 133-day trial than did cattle fed the unmixed diet. Annual ownership and repair costs were assumed to equal $2356. If yearling feeder cattle sold for$8O/cwt and if corn, hay and corn silage were worth $90,$80 and $25 per ton, respectively, it would take a minimum of 114 head on feed for 133 days each year to pay annual costs for the wagon. The economic analysis of the data from this trial suggests that even relatively small cattle feeding operations should strongly consider investing in a mixer wagon with a scale

Método preliminar para la evaluación de la calidad de superficies ecuestres

Las superficies ecuestres de arena y césped propuestas para la competencia o entrenamiento deben cumplir requisitos funcionales para asegurar calidad de la performance, bienestar animal y seguridad del jinete1. La FEI2 definió las características de las superficies ecuestres. Firmeza, amortiguación, rebote, agarre, uniformidad y consistencia. En las superficies donde se realizan competencias a nivel nacional e internacional como también en las superficies de entrenamiento es necesario monitorear los aspectos críticos de la respuesta de la superficie3. El objetivo del ensayo diseñar un método de evaluación que permita crear un protocolo de aplicación en certificación de competencias deportivas. El experimento consistió en relevar diversas superficies existentes en establecimientos ecuestres de distinto objetivo. Se realizaron mediciones mediante cuadrículas de 5x5 o de 10x10, de acuerdo al tamaño de la superficie. En cada estación se realizaron mediciones de espesor de amortiguación, test de Impacto, con un dispositivo similar al Clegg Hammer. La tracción longitudinal, se midió utilizando un dispositivo según norma ASTM F2333-04, además se utilizó el dispositivo denominado Going Stick. Se realizaron ensayos de caracterización gravimétrica de la arena y los materiales adicionados. El Contenido Volumétrico de Humedad4 se monitoreó con TDR. Los datos obtenidos se analizaron mediante ANVA y test de Tuckey. Las conclusiones preliminares indican que el método permite establecer con un grado de confianza las diferencias en uniformidad en distintos sectores de una superficie. Estas diferencias permiten diagnosticar el estado de la superficie y de este modo proceder con la práctica adecuada para su restauración. Repetir el método luego de las prácticas de restauración permiten monitorear la evolución de los parámetros medidos y se esperaría que signifiquen una mejora en las propiedades funcionales. Este método podría ser utilizado como protocolo de certificación de superficies ecuestres en competencias deportivas

Measurement of CP violation at a Neutrino Factory

The prospects of measuring CP violation in the leptonic sector using the intense neutrino beams arising from muon decay in the straight sections of a muon accumulator ring (the so-called neutrino factory) are discussed.Comment: Invited talk given at the CP2000 Conference in Ferrara, September, 200

The Centurion 18 telescope of the Wise Observatory

We describe the second telescope of the Wise Observatory, a 0.46-m Centurion 18 (C18) installed in 2005, which enhances significantly the observing possibilities. The telescope operates from a small dome and is equipped with a large-format CCD camera. In the last two years this telescope was intensively used in a variety of monitoring projects. The operation of the C18 is now automatic, requiring only start-up at the beginning of a night and close-down at dawn. The observations are mostly performed remotely from the Tel Aviv campus or even from the observer's home. The entire facility was erected for a component cost of about 70k$ and a labor investment of a total of one man-year. We describe three types of projects undertaken with this new facility: the measurement of asteroid light variability with the purpose of determining physical parameters and binarity, the following-up of transiting extrasolar planets, and the study of AGN variability. The successful implementation of the C18 demonstrates the viability of small telescopes in an age of huge light-collectors, provided the operation of such facilities is very efficient.Comment: 16 pages, 13 figures, some figures quality was degraded, accepted for publication in Astrophysics and Space Scienc