Efficiency of Higher Order Finite Elements for the Analysis of Seismic Wave Propagation

The analysis of wave propagation problems in linear damped media must take into account both propagation features and attenuation process. To perform accurate numerical investigations by the finite differences or finite element method, one must consider a specific problem known as the numerical dispersion of waves. Numerical dispersion may increase the numerical error during the propagation process as the wave velocity (phase and group) depends on the features of the numerical model. In this paper, the numerical modelling of wave propagation by the finite element method is thus analyzed and dis-cussed for linear constitutive laws. Numerical dispersion is analyzed herein through 1D computations investigating the accuracy of higher order 15-node finite elements towards numerical dispersion. Concerning the numerical analy-sis of wave attenuation, a rheological interpretation of the classical Rayleigh assumption has for instance been previously proposed in this journal

Seismic site effects in a deep alluvial basin: numerical analysis by the boundary element method

The main purpose of the paper is the numerical analysis of seismic site effects in Caracas (Venezuela). The analysis is performed considering the boundary element method in the frequency domain. A numerical model including a part of the local topography is considered, it involves a deep alluvial deposit on an elastic bedrock. The amplification of seismic motion (SH-waves, weak motion) is analyzed in terms of level, occurring frequency and location. In this specific site of Caracas, the amplification factor is found to reach a maximum value of 25. Site effects occur in the thickest part of the basin for low frequencies (below 1.0 Hz) and in two intermediate thinner areas for frequencies above 1.0 Hz. The influence of both incidence and shear wave velocities is also investigated. A comparison with microtremor recordings is presented afterwards. The results of both numerical and experimental approaches are in good agreement in terms of fundamental frequencies in the deepest part of the basin. The boundary element method appears to be a reliable and efficient approach for the analysis of seismic site effects

Local amplification of deep mining induced vibrations - Part.2: Simulation of the ground motion in a coal basin

This work investigates the impact of deep coal mining induced vibrations on surface constructions using numerical tools. An experimental study of the geological site amplification and of its influence on mining induced vibrations has already been published in a previous paper (Part 1: Experimental evidence for site effects in a coal basin). Measurements have shown the existence of an amplification area in the southern part of the basin where drilling data have shown the presence of particularly fractured and soft stratigraphic units. The present study, using the Boundary Element Method (BEM) in the frequency domain, first investigates canonical geological structures in order to get general results for various sites. The amplification level at the surface is given as a function of the shape of the basin and of the velocity contrast with the bedrock. Next, the particular coal basin previously studied experimentally (Driad-Lebeau et al., 2009) is modeled numerically by BEM. The amplification phenomena characterized numerically for the induced vibrations are found to be compatible with the experimental findings: amplification level, frequency range, location. Finally, the whole work was necessary to fully assess the propagation and amplification of mine induced vibrations. The numerical results quantifying amplification can also be used to study other coal basins or various types of alluvial sites

Dynamic soil response for strong earthquakes: a simplified non-linear constitutive model

International audienc

Effects of irradiation on Plasmodium falciparum sporozoite hepatic development: implications for the design of pre-erythrocytic malaria vaccines.

Immunization with irradiation-attenuated Plasmodium sporozoites confer protection against live sporozoite challenge. Protection relies primarily on cytotoxic lymphocyte activity against infected hepatocytes, and is suppressed when sporozoites are over-irradiated. Here, we demonstrate that over-irradiated (25-30 krad) Plasmodium falciparum sporozoites invade human hepatocytes and transform into uninucleate liver-trophozoites with the same efficiency as non-irradiated and irradiation-attenuated (12-15 krad) sporozoites. Since hepatocytes infected with over-irradiated non-protective sporozoites are likely to express sporozoite-derived peptide/major histocompatibility complex class I molecules on their surface, our results strongly suggest that sporozoite proteins are not the main immunogens involved in protection, and thus may not per se constitute proper malaria vaccine candidates