103 research outputs found
Fine structure of Vavilov-Cherenkov radiation near the Cherenkov threshold
We analyze the Vavilov-Cherenkov radiation (VCR) in a dispersive
nontransparent dielectric air-like medium both below and above the Cherenkov
threshold, in the framework of classical electrodynamics. It is shown that the
transition to the subthreshold energies leads to the destruction of
electromagnetic shock waves and to the sharp reduction of the frequency domain
where VCR is emitted. The fine wake-like structure of the Vavilov-Cherenkov
radiation survives and manifests the existence of the subthreshold radiation in
the domain of anomalous dispersion. These domains can approximately be defined
by the two phenomenological parameters of the medium, namely, the effective
frequency of oscillators and the damping describing an interaction with the
other degrees of freedom.Comment: 9 pages, 6 figure
Antecedents and outcomes of consumer environmentally friendly attitudes and behaviour
With the intensification of problems relating to the environment, a growing number of consumers are becoming more ecologically conscious in their preferences and purchases of goods. This paper presents the results of a study conducted among 500 Cypriot consumers, focusing on the factors that shape consumer environmental attitudes and behaviour, as well as on the resulting outcomes. The findings confirmed that both the inward and outward environmental attitudes of a consumer are positively influenced by his/her degree of collectivism, long-term orientation, political involvement, deontology, and law obedience, but have no connection with liberalism. The adoption of an inward environmental attitude was also found to be conducive to green purchasing behaviour that ultimately leads to high product satisfaction. On the other hand, an outward environmental attitude facilitates the adoption of a general environmental behaviour, which is responsible for greater satisfaction with life. The findings of the study have important implications for shaping effective company offerings to consumers in target markets, as well as formulating appropriate policies at the governmental level to enhance environmental sensitivity among citizens
Development and external validation study of a melanoma risk prediction model incorporating clinically assessed naevi and solar lentigines
Background:
Melanoma risk prediction models could be useful for matching preventive interventions to patients’ risk.
Objectives:
To develop and validate a model for incident first‐primary cutaneous melanoma using clinically assessed risk factors.
Methods:
We used unconditional logistic regression with backward selection from the Australian Melanoma Family Study (461 cases and 329 controls) in which age, sex and city of recruitment were kept in each step, and we externally validated it using the Leeds Melanoma Case–Control Study (960 cases and 513 controls). Candidate predictors included clinically assessed whole‐body naevi and solar lentigines, and self‐assessed pigmentation phenotype, sun exposure, family history and history of keratinocyte cancer. We evaluated the predictive strength and discrimination of the model risk factors using odds per age‐ and sex‐adjusted SD (OPERA) and the area under curve (AUC), and calibration using the Hosmer–Lemeshow test.
Results:
The final model included the number of naevi ≥ 2 mm in diameter on the whole body, solar lentigines on the upper back (a six‐level scale), hair colour at age 18 years and personal history of keratinocyte cancer. Naevi was the strongest risk factor; the OPERA was 3·51 [95% confidence interval (CI) 2·71–4·54] in the Australian study and 2·56 (95% CI 2·23–2·95) in the Leeds study. The AUC was 0·79 (95% CI 0·76–0·83) in the Australian study and 0·73 (95% CI 0·70–0·75) in the Leeds study. The Hosmer–Lemeshow test P‐value was 0·30 in the Australian study and < 0·001 in the Leeds study.
Conclusions:
This model had good discrimination and could be used by clinicians to stratify patients by melanoma risk for the targeting of preventive interventions.
What's already known about this topic?
Melanoma risk prediction models may be useful in prevention by tailoring interventions to personalized risk levels.
For reasons of feasibility, time and cost many melanoma prediction models use self‐assessed risk factors. However, individuals tend to underestimate their naevus numbers.
What does this study add?
We present a melanoma risk prediction model, which includes clinically‐assessed whole‐body naevi and solar lentigines, and self‐assessed risk factors including pigmentation phenotype and history of keratinocyte cancer.
This model performs well on discrimination, the model's ability to distinguish between individuals with and without melanoma, and may assist clinicians to stratify patients by melanoma risk for targeted preventive interventions
The artificial intelligence-based model ANORAK improves histopathological grading of lung adenocarcinoma
The introduction of the International Association for the Study of Lung Cancer grading system has furthered interest in histopathological grading for risk stratification in lung adenocarcinoma. Complex morphology and high intratumoral heterogeneity present challenges to pathologists, prompting the development of artificial intelligence (AI) methods. Here we developed ANORAK (pyrAmid pooliNg crOss stReam Attention networK), encoding multiresolution inputs with an attention mechanism, to delineate growth patterns from hematoxylin and eosin-stained slides. In 1,372 lung adenocarcinomas across four independent cohorts, AI-based grading was prognostic of disease-free survival, and further assisted pathologists by consistently improving prognostication in stage I tumors. Tumors with discrepant patterns between AI and pathologists had notably higher intratumoral heterogeneity. Furthermore, ANORAK facilitates the morphological and spatial assessment of the acinar pattern, capturing acinus variations with pattern transition. Collectively, our AI method enabled the precision quantification and morphology investigation of growth patterns, reflecting intratumoral histological transitions in lung adenocarcinoma
Predicting land suitability classes The example of irrigated sugar-cane at Bacita Estate in Nigeria
Incl. 11 mapsAvailable from British Library Document Supply Centre- DSC:D67340/86 / BLDSC - British Library Document Supply CentreSIGLEGBUnited Kingdo
A directory of dental services for the disabled
Abstract— A directory of dental services for the disabled has facilitated more appropriate patient referral at the local level. It has also provided a broad analysis of the available dental services throughout the State. The directory is in a form which periodically can be brought up to date. 1984 Australian Dental Associatio
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